Thalidomide-SH
Thalidomide-SH is an E3 ubiquitin ligase cereblon (CRBN) ligand that recruits cereblon protein. Thalidomide-SH is a Thalidomide (HY-14658) derivative. Thalidomide-SH can be linked to a target protein ligand via a linker to form a PROTAC, such as SIAIS056 (HY-180969).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 2378582-97-7
- 화학식: C13H10N2O4S
- 분자량:290.29
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2378582-97-7
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분자량 290.29
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화학식 C13H10N2O4S
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SMILES
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3S)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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