Lavoltidine
Lavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist. Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia.
For research use only. We do not sell to patients.
- CAS No.: 76956-02-0
- Formula: C19H29N5O2
- Molecular Weight:359.47
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Histamine Receptor Isoforms
More
Biological Activity
|
H2 Receptor |
Lavoltidine treatment for 6 months inhibits gastric tumors in H felis-infected INS-GAS mice[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Male hypergastrinemic mice (INS-GAS mice) infected with Helicobacter felis[1]
-
Dosage:0.5 g/L
-
Administration:Orally (drinking water); changed weekly; for 3 months
-
Result:Showed partial suppression of both gastric acid secretion and progression to neoplasia.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 76956-02-0
-
Molecular Weight 359.47
-
Formula C19H29N5O2
-
SMILES
OCC1=NN(C(NCCCOC2=CC=CC(CN3CCCCC3)=C2)=N1)C
-
Synonyms
Loxtidine; AH-234844
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lavoltidine Related Classifications
HY-121450 Related Classifications
Powered by Bioz