Lck Inhibitor III
Lck Inhibitor III is a Lck inhibitor with an IC50 of 867 nM. Lck Inhibitor III inhibits the production of interleukin-2 (IL-2). Lck Inhibitor III can be used in the study of autoimmune diseases.
For research use only. We do not sell to patients.
- CAS No.: 1188890-30-3
- Formula: C25H30N6O4
- Molecular Weight:478.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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Lck 867 nM (IC50) |
IL-2 1.270 μM (IC50) |
In Vitro
Lck Inhibitor III (Compound 12h) inhibits purified lymphocyte-specific kinase (Lck) with an IC50 of 867 nM[1].
The intrinsic clearance of Lck Inhibitor III (1 μM; 1 h) in cryopreserved rat hepatocyte suspensions is 48 mL/min kg[1].
Lck Inhibitor III inhibits IL-2 production in Jurkat cells with an IC50 of 1.270 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1188890-30-3
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Molecular Weight 478.54
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Formula C25H30N6O4
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SMILES
CC1=CC=C(C=C1NC2=NC(N3C4=CC=CC=C4N=C3)=NC(OCCN5CCOCC5)=C2)OC.O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lck Inhibitor III Related Classifications
HY-112335 Related Classifications
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