1. Protein Tyrosine Kinase/RTK Immunology/Inflammation
  2. Src Interleukin Related
  3. Lck Inhibitor III

Lck Inhibitor III (compound 12h) is a potent Lck inhibitor, with an IC50 of 867 nM. Lck Inhibitor III inhibits IL-2 synthesis in Jurkat cells, with an IC50 of 1.270 μM.

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Lck Inhibitor III Chemical Structure

Lck Inhibitor III Chemical Structure

CAS No. : 1188890-30-3

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Description

Lck Inhibitor III (compound 12h) is a potent Lck inhibitor, with an IC50 of 867 nM. Lck Inhibitor III inhibits IL-2 synthesis in Jurkat cells, with an IC50 of 1.270 μM[1].

IC50 & Target

IL-2

 

Lck

867 nM (IC50)

Molecular Weight

478.54

Formula

C25H30N6O4

CAS No.
SMILES

CC1=CC=C(OC)C=C1NC2=NC(N3C4=CC=CC=C4N=C3)=NC(OCCN5CCOCC5)=C2.O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Lck Inhibitor III
Cat. No.:
HY-112335
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