LY53857
LY53857 is a potent antagonist of vasoconstriction and serotonin-mediated 5-HT2 receptors. LY53857 did not reduce mean arterial blood pressure in spontaneously hypertensive rats (SHR) at doses that blocked the depressor response to serotonin and blocked central serotonin receptors. In addition, LY53857 was able to enhance neurotransmitter release in rat vas deferens and guinea pig ileal nerves.
For research use only. We do not sell to patients.
- CAS No.: 60634-51-7
- Formula: C27H36N2O7
- Molecular Weight:500.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 5-HT Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 60634-51-7
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Molecular Weight 500.58
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Formula C27H36N2O7
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SMILES
OC(/C=C\C(O)=O)=O.CC(N1C2=C3C([C@]4([H])[C@@](N(C[C@@H](C4)C(OC(C)C(O)C)=O)C)([H])CC3=C1)=CC=C2)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)