1. Metabolic Enzyme/Protease
  2. Thrombin
  3. Melagatran

Melagatran 

Cat. No.: HY-129056
Handling Instructions

Melagatran is a direct and orally active inhibitor of thrombin, without interacting with any other enzymes in the coagulation cascade or fibrinolytic enzymes aside from thrombin. Melagatran does not require endogenous co-factors for its antithrombin effect and may help to alleviate some of the damaging effects of endotoxemia. Melagatran has the potential to provide a rational approach in the prevention of arterial occlusion.

For research use only. We do not sell to patients.

Melagatran Chemical Structure

Melagatran Chemical Structure

CAS No. : 159776-70-2

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Description

Melagatran is a direct and orally active inhibitor of thrombin, without interacting with any other enzymes in the coagulation cascade or fibrinolytic enzymes aside from thrombin. Melagatran does not require endogenous co-factors for its antithrombin effect and may help to alleviate some of the damaging effects of endotoxemia[1]. Melagatran has the potential to provide a rational approach in the prevention of arterial occlusion[2].

IC50 & Target

Thrombin[1]

Molecular Weight

429.51

Formula

C₂₂H₃₁N₅O₄

CAS No.

159776-70-2

SMILES

NC(C(C=C1)=CC=C1CNC([[email protected]@H]2CCN2C([[email protected]@H](C3CCCCC3)NCC(O)=O)=O)=O)=N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

MelagatranThrombinInhibitorinhibitorinhibit

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