1. MAPK/ERK Pathway
  2. JNK
  3. (-)-Zuonin A

(-)-Zuonin A (Synonyms: D-Epigalbacin)

Cat. No.: HY-N7394A Purity: 99.84%
Handling Instructions

(-)-Zuonin A (D-Epigalbacin), a naturally occurring lignin, is a potent, selective JNKs inhibitor, with IC50s of 1.7 μM, 2.9 μM and 1.74 μM for JNK1, JNK2 and JNK3, respectively.

For research use only. We do not sell to patients.

(-)-Zuonin A Chemical Structure

(-)-Zuonin A Chemical Structure

CAS No. : 84709-25-1

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1 mg USD 200 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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(-)-Zuonin A (D-Epigalbacin), a naturally occurring lignin, is a potent, selective JNKs inhibitor, with IC50s of 1.7 μM, 2.9 μM and 1.74 μM for JNK1, JNK2 and JNK3, respectively[1].

IC50 & Target[1]


1.7 μM (IC50)


2.9 μM (IC50)


1.74 μM (IC50)

In Vitro

(−)-zuonin A binds the D-recruitment site (DRS) of JNK, a recruitment site utilized by substrates and other substrates to dock onto and recognize MAPKs[1].
(−)-zuonin A inhibits the activation and phosphorylation of JNK by MKK4 and MKK7[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight





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Structure Classification

Room temperature in continental US; may vary elsewhere.


4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (293.80 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9380 mL 14.6899 mL 29.3798 mL
5 mM 0.5876 mL 2.9380 mL 5.8760 mL
10 mM 0.2938 mL 1.4690 mL 2.9380 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
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