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Cat. No.: HY-14337

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MS 245

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

MS 245 is an antagonist of the 5-HT₆ receptor wih an K_i value of 1.5 nM.

For research use only. We do not sell to patients.

CAS No.: 263384-65-2
Formula: C₁₉H₂₂N₂O₃S
Molecular Weight:358.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

MS 245 Chemical Structure

CAS No.: 263384-65-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Publications (1)
Purity & Documentation
References
Calculators
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Bioz

Biological Activity

Description

MS 245 is an antagonist of the 5-HT₆ receptor wih an K_i value of 1.5 nM^[1].

IC₅₀ & Target

5-HT₆ Receptor

1.5 nM (Ki)

All 5-HT Receptor Isoforms :

Chemical Information

CAS No. 263384-65-2
Molecular Weight 358.45
Formula C₁₉H₂₂N₂O₃S
SMILES

O=S(N(C1=CC=C(OC)C=C21)C=C2CCN(C)C)(C3=CC=CC=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Food Res Int

Disruption of the gut microbiota induces the LCA/TRPV6 signalling axis, impairing desmosome junctions in vitamin A-deficient rats. [Abstract]

2025 Dec;222(Pt 1):117656. PMID: 41267264

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Manik Pullagurla, et al. Modulation of the stimulus effects of (+)amphetamine by the 5-HT6 antagonist MS-245. Modulation of the stimulus effects of (+)amphetamine by the 5-HT6 antagonist MS-245. Pharmacol Biochem Behav. 2004 Jun;78(2):263-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Publications (1)
Purity & Documentation
References

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MS 245

Publications Citing Use of MedChemExpress (MCE) MS 245

All 5-HT Receptor Isoforms