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NF-κB-IN-14

NF-κB-IN-14 (compound 5e) significantly inhibits nitric oxide production in LPS-induced macrophages (IC50: 6.4 μM). NF-κB-IN-14 disrupts the TLR4-MyD88 protein interaction, leading to the suppression of the NF-κB signaling pathway suppression. NF-κB-IN-14 reduces ear edema and inflammation in an atopic dermatitis mouse model.

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  • CAS No.: 3019972-01-8
  • Formula: C15H12Cl2N4
  • Molecular Weight:319.19
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • NF-κB-IN-14 Chemical Structure
    NF-κB-IN-14 Chemical Structure
CAS No.: 3019972-01-8
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All NF-κB Isoforms

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All Toll-like Receptor (TLR) Isoforms

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100 mg

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  • NF-κB-IN-14