MI-217
Based on 1 Customer Validation
MI-217 is a potent SIRT3 inhibitor. MI-217 induces MDA-MB-231 apoptosis. MI-217 can be used in the study of breast cancer.
For research use only. We do not sell to patients.
- Purity: 99.52%
- CAS No.: 301202-06-2
- Formula: C10H12N4O2S
- Molecular Weight:252.29
-
Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Vero | IC50 |
0.5 mM
Compound: 2h
|
Compound tested on intracellular parasites Toxoplasma gondii in vero cells after 24 h
Compound tested on intracellular parasites Toxoplasma gondii in vero cells after 24 h
|
[PMID: 15863319] |
| Vero | IC50 |
2.5 mM
Compound: 2h
|
Compound tested on vero cells infected with Toxoplasma gondii after 24 h
Compound tested on vero cells infected with Toxoplasma gondii after 24 h
|
[PMID: 15863319] |
Chemical Information
-
CAS No. 301202-06-2
-
Appearance Solid
-
Molecular Weight 252.29
-
Formula C10H12N4O2S
-
Color Light yellow to yellow
-
SMILES
S=C(N/N=C/C1=CC=C([N+]([O-])=O)C=C1)NCC
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (396.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (265 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9637 mL | 19.8185 mL | 39.6369 mL | 99.0923 mL |
| 5 mM | 0.7927 mL | 3.9637 mL | 7.9274 mL | 19.8185 mL | |
| 10 mM | 0.3964 mL | 1.9818 mL | 3.9637 mL | 9.9092 mL | |
| 15 mM | 0.2642 mL | 1.3212 mL | 2.6425 mL | 6.6062 mL | |
| 20 mM | 0.1982 mL | 0.9909 mL | 1.9818 mL | 4.9546 mL | |
| 25 mM | 0.1585 mL | 0.7927 mL | 1.5855 mL | 3.9637 mL | |
| 30 mM | 0.1321 mL | 0.6606 mL | 1.3212 mL | 3.3031 mL | |
| 40 mM | 0.0991 mL | 0.4955 mL | 0.9909 mL | 2.4773 mL | |
| 50 mM | 0.0793 mL | 0.3964 mL | 0.7927 mL | 1.9818 mL | |
| 60 mM | 0.0661 mL | 0.3303 mL | 0.6606 mL | 1.6515 mL | |
| 80 mM | 0.0495 mL | 0.2477 mL | 0.4955 mL | 1.2387 mL | |
| 100 mM | 0.0396 mL | 0.1982 mL | 0.3964 mL | 0.9909 mL |
MI-217 Related Classifications
HY-163676 Related Classifications
Powered by Bioz