NLRP3-IN-69
NLRP3-IN-69 (Compound 23) inhibits the activation of NF-κB p65 and the formation of NLRP3 inflammasome. NLRP3-IN-69 inhibits LPS (HY-D1056)-induced overexpression of IL-1β, iNOS and COX-2, inhibits NO generation (IC50=5.66 μM), thereby exhibiting anti-inflammatory activity.
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- CAS. Nr.: 3027608-60-9
- Formel: C25H24O7
- Molecular Weight:436.45
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 3027608-60-9
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Molecular Weight 436.45
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Formel C25H24O7
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SMILES
COC1=C(OC)C(OC)=CC(/C=C/C(OC2=CC(C=CC([C@@H](C(O)=O)C)=C3)=C3C=C2)=O)=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
NLRP3-IN-69 Related Classifications
HY-170836 Related Classifications
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