Meliaceae Extract

Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. Lyoniresinol has radical scavenging activities against DPPH with an IC₅₀ of 82.4 μM.

Nimonol (Nimocinol) is a tetranortriterpenoid limonoid present in the leaves of Azadirachta indica, and it undergoes photolysis to generate Nimonolide. Nimonol interferes with insect growth processes, exerts antifeedant and insecticidal effects, and exhibits insecticidal toxicity against the fourth-instar larvae of Aedes aegypti. Nimonol is used in research related to pest control.

Nimolicinol is a tetranortriterpenoid compound. Nimolicinol binds to the ephrinB2 interaction interface of the Nipah virus attachment glycoprotein, interfering with virus-host cell adhesion, and exhibits anti-Plasmodium, anti-SARS-CoV-2, and larvicidal activities. Nimolicinol can be used in research on Nipah virus infection, malaria, COVID-19, and filariasis.

Meliatoosenin O is a limonoid found in the fruits of Melia toosendan. Meliatoosenin O inhibits TNF-α-induced NF-κB luciferase activation in HepG2-NF-κB-Luc cells.

Meliatoosenin R is a ring C-seco limonoid that can be found in the fruits of Melia toosendan. Meliatoosenin R can be used in studies related to limonoid chemistry, lung cancer, and leukemia.

Azedarachin B is a tetranortriterpenoid limonoid analog that is isolated and extracted from the root bark of Melia toosendan and the roots of Melia azedarach. Azedarachin B exhibits potent insecticidal activity and tumor cytotoxicity. Azedarachin B can be used in research on cancer and biopesticides.

Meliatoosenin Q is a ring C-seco limonoid that can be found in the fruits of Melia toosendan. Meliatoosenin Q is used in studies related to limonoid chemistry, lung cancer, and leukemia.

12α-Hydroxymeliatoosenin I is a limonoid compound found in the roots of Trichilia sinensis. In the MTT assay, 12α-Hydroxymeliatoosenin I exhibits no significant growth inhibitory activity against K562, SGC-7901, and BEL-7402 cells, with all IC₅₀ values exceeding 40 μM. 12α-Hydroxymeliatoosenin I is applicable to studies related to limonoid natural products and tumor cell growth.

6-Deacetyloxy-7-deacetylchisocheton is a limonoid compound found in the bark of Melia azedarach. 6-Deacetyloxy-7-deacetylchisocheton exhibits cytotoxicity against cancer cells. 6-Deacetyloxy-7-deacetylchisocheton can be used in cancer research.

Amoorastatin is a limonoid tetranortriterpene that is isolated from the seeds of Aphanamixis grandifolia. Amoorastatin exhibits antitumor activity and exerts its inhibitory effects through alkylation of amine and thiol sites on biopolymers via its 14,15β-epoxide. Amoorastatin can be used for research on lymphocytic leukemia.

Toosendanin (Standard) is the analytical standard of Toosendanin. This product is intended for research and analytical applications. Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities.

Toona sinensis polysaccharide is a polysaccharide derived from Toona sinensis.

Corosin (Vismiaefolic acid) is a triterpenoid compound that can be isolated from Chisocheton paniculatus.

Trichilin B is a limonoid compound found in the twigs and leaves of Trichilia connaroides. Trichilin B exhibits no in vitro cytotoxic activity against tumor cell lines.

21-Hydroxyisoohchininolide is a salannin-type limonoid. 21-Hydroxyisoohchininolide inhibits lipopolysaccharide (LPS, HY-D1056)-induced nitric oxide production in mouse macrophages. 21-Hydroxyisoohchininolide exhibits cytotoxic activity against leukemia cells and breast cancer cells. 21-Hydroxyisoohchininolide suppresses phorbol 12-myristate 13-acetate (PMA) (HY-18739)-induced activation of Epstein-Barr virus early antigen in lymphocytes. 21-Hydroxyisoohchininolide can be used for the research of leukemia, breast cancer and inflammatory diseases.