Perfluoroenanthic acid-¹³C₄  (Synonyms: Perfluoroheptanoic acid-¹³C₄; Tridecafluoroheptanoic acid-¹³C₄; PFHpA-¹³C₄)

Perfluoroenanthic acid-¹³C₄ (Perfluoroheptanoic acid-¹³C₄) is the ¹³C-labeled Perfluoroenanthic acid (HY-21197). Perfluoroenanthic acid (Perfluoroheptanoic acid) is a type of perfluoroalkyl substance (PFAS) that can negatively impact the development of seminiferous tubules and m6A RNA methylation in the testes of offspring mice when exposed during pregnancy, consequently disrupting spermatogenesis and leading to reproductive toxicity. Perfluoroenanthic acid alters the morphology of dendritic spines and synaptic formation in primary cortical neuron cultures, enhancing neuronal activity and synaptic transmission, and increasing the expression of excitatory synapse-related proteins Synaptophysin and PSD95^[1][2].

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

368.03

C₃¹³C₄HF₁₃O₂

2328024-55-9

375-85-9

FC(F)(F)C(F)(F)C(F)(F)[13C](F)(F)[13C](F)(F)[13C](F)(F)[13C](O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.