PI3K-IN-26
PI3K-IN-26 is a potent PI3K inhibitor with an IC50 of 36 nM for SU-DHL-6 cells (WO2016066142A1, compound 1).
For research use only. We do not sell to patients.
- CAS No.: 1918151-65-1
- Formula: C21H18N6OS
- Molecular Weight:402.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| SU-DHL-6 | IC50 |
36 nM
Compound: 32
|
Cytotoxicity against human SU-DHL6 cells
Cytotoxicity against human SU-DHL6 cells
|
[PMID: 30582813] |
Chemical Information
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CAS No. 1918151-65-1
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Molecular Weight 402.47
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Formula C21H18N6OS
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SMILES
O=C1C(C2=CC=CC=C2)=C(C(NC3=C4N=CNC4=NC=N3)C)C=C5N1C(C)=CS5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)