Pipercide

Cat. No.: HY-N10743 Purity: 99.59%: Data Sheet
COA

SDS
Handling Instructions
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Pipercide is an amide of piper nigrum fruits. Pipercide has larvicidal activity to mosquito. Pipercide acts on the nervous system and induces repetitive discharge on the central nerve cord. Pipercide can be used as an insecticide.

For research use only. We do not sell to patients.

Pipercide Chemical Structure

CAS No. : 54794-74-0

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	> 40 μM Compound: 16	Antiproliferative activity against human A549 cells after 3 days by SRB assay Antiproliferative activity against human A549 cells after 3 days by SRB assay	[PMID: 25241925]
DU-145	IC₅₀	> 40 μM Compound: 16	Antiproliferative activity against human DU145 cells after 3 days by SRB assay Antiproliferative activity against human DU145 cells after 3 days by SRB assay	[PMID: 25241925]
HepG2	IC₅₀	3.7 μM Compound: Pipercide	Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate addition measured after 25 mins by liquid scintillation counting analysis Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate addition measured after 25 mins by liquid scintillation counting analysis	[PMID: 23419736]
Hepatocyte	IC₅₀	2.6 μM Compound: 27, retrofractamide B	Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cytotoxicity after 20 hrs by MTT assay relative to untreated control Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cytotoxicity after 20 hrs by MTT assay relative to untreated control	[PMID: 19775895]
KB	IC₅₀	> 40 μM Compound: 16	Antiproliferative activity against human KB cells after 3 days by SRB assay Antiproliferative activity against human KB cells after 3 days by SRB assay	[PMID: 25241925]
MCF7	IC₅₀	> 40 μM Compound: 16	Antiproliferative activity against human MCF7 cells after 3 days by SRB assay Antiproliferative activity against human MCF7 cells after 3 days by SRB assay	[PMID: 25241925]
MDA-MB-231	IC₅₀	> 40 μM Compound: 16	Antiproliferative activity against human MDA-MB-231 cells after 3 days by SRB assay Antiproliferative activity against human MDA-MB-231 cells after 3 days by SRB assay	[PMID: 25241925]
SK-BR-3	IC₅₀	> 40 μM Compound: 16	Antiproliferative activity against human SK-BR-3 cells after 3 days by SRB assay Antiproliferative activity against human SK-BR-3 cells after 3 days by SRB assay	[PMID: 25241925]
WI-38	IC₅₀	2 μM Compound: 4	Induction of senescence in human WI-38 cells Induction of senescence in human WI-38 cells	[PMID: 38436272]
ZR-75-1	IC₅₀	> 40 μM Compound: 16	Antiproliferative activity against human ZR-75-1 cells after 3 days by SRB assay Antiproliferative activity against human ZR-75-1 cells after 3 days by SRB assay	[PMID: 25241925]

Molecular Weight

355.47

Formula

C₂₂H₂₉NO₃

CAS No.

54794-74-0

Appearance

Solid

Color

White to off-white

SMILES

CC(C)CNC(/C=C/C=C/CCCC/C=C/C1=CC=C(OCO2)C2=C1)=O

Structure Classification

Others

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL (70.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8132 mL	14.0659 mL	28.1318 mL
5 mM	0.5626 mL	2.8132 mL	5.6264 mL
10 mM	0.2813 mL	1.4066 mL	2.8132 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.59%

Select Batch:

Data Sheet (264 KB) SDS (252 KB)

COA (241 KB) HNMR (267 KB) LCMS (102 KB)

Handling Instructions (2659 KB)

References

[1]. Park IK, et al. Larvicidal activity of isobutylamides identified in Piper nigrum fruits against three mosquito species. J Agric Food Chem. 2002 Mar 27;50(7):1866-70. [Content Brief]

[2]. Makoto HATAKOSHI, et al. The Knockdown Activity an Nervous Effect of Piercide against American Cockroach, Periplaneta Americana. Applied Entomology and Zoology. 1984 Volume 19 Issue 3 Pages 288-292.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.8132 mL	14.0659 mL	28.1318 mL	70.3294 mL
	5 mM	0.5626 mL	2.8132 mL	5.6264 mL	14.0659 mL
	10 mM	0.2813 mL	1.4066 mL	2.8132 mL	7.0329 mL
	15 mM	0.1875 mL	0.9377 mL	1.8755 mL	4.6886 mL
	20 mM	0.1407 mL	0.7033 mL	1.4066 mL	3.5165 mL
	25 mM	0.1125 mL	0.5626 mL	1.1253 mL	2.8132 mL
	30 mM	0.0938 mL	0.4689 mL	0.9377 mL	2.3443 mL
	40 mM	0.0703 mL	0.3516 mL	0.7033 mL	1.7582 mL
	50 mM	0.0563 mL	0.2813 mL	0.5626 mL	1.4066 mL
	60 mM	0.0469 mL	0.2344 mL	0.4689 mL	1.1722 mL

Pipercide Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pipercide54794-74-0Parasiteamidemosquitoinsecticidenervous systemInhibitorinhibitorinhibit

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Pipercide

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Pipercide Related Antibodies

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Complete Stock Solution Preparation Table

Pipercide Related Classifications

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