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Cat. No.: HY-103404

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PNU-96415E

PNU-96415E is a selective D₄/5-HT_2A antagonist. PNU-96415E may have potential antipsychotic efficacy.

For research use only. We do not sell to patients.

CAS No.: 170856-41-4
Formula: C₂₁H₂₇Cl₂FN₂O
Molecular Weight:413.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

PNU-96415E Chemical Structure

CAS No.: 170856-41-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

PNU-96415E is a selective D₄/5-HT_2A antagonist. PNU-96415E may have potential antipsychotic efficacy^[1].

IC₅₀ & Target^[1]

D₄ Receptor

5-HT_2A Receptor

All Dopamine Receptor Isoforms :

All 5-HT Receptor Isoforms :

In Vivo

PNU-96415E blockes 5-HTP-induced bead twitches in mice and stereotypic behaviours produced by high doses of amphetamine and methylphenidate^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 170856-41-4
Molecular Weight 413.36
Formula C₂₁H₂₇Cl₂FN₂O
SMILES

FC1=CC=C(N2CCN(CCC3C4=CC=CC=C4CCO3)CC2)C=C1.[H]Cl.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kulkarni SK, et al. Dopamine D4 receptors and development of newer antipsychotic drugs. Fundam Clin Pharmacol. 2000;14(6):529-539. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Purity & Documentation
References

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PNU-96415E

All Dopamine Receptor Isoforms

All 5-HT Receptor Isoforms