Polymyxin T1
Polymyxin T1 is an antibiotic found in Bacillus polymyxa E-12. Polymyxin T1 has an effect against Gram-negative bacteria and a weak effect against Gram-positive bacteria.
For research use only. We do not sell to patients.
- CAS No.: 63700-39-0
- Formula: C58H102N16O12
- Molecular Weight:1215.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
Chemical Information
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CAS No. 63700-39-0
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Molecular Weight 1215.53
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Formula C58H102N16O12
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SMILES
CCC(CCCCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CCNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](NC([C@@H](NC1=O)CCN)=O)CC2=CC=CC=C2)=O)CC(C)C)=O)CCN)=O)CCN)=O)CC(C)C)=O)=O)CCN)=O)[C@H](O)C)=O)CCN)=O)C
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Sequence
6-Methyloctanoic acid-Dab-Thr-Dab-cyclo(Dab-Dab-DPhe-Leu-Dab-Dab-Leu)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Polymyxin T1 Related Classifications
HY-N15120 Related Classifications
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