Pomalidomide-5-O-CH3
Pomalidomide-5-O-CH3 is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-O-CH3 can be connected to the ligand for protein by a linker to form PROTAC.
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- CAS 番号: 1547163-02-9
- 分子式: C14H13N3O5
- 分子量:303.27
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1547163-02-9
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分子量 303.27
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分子式 C14H13N3O5
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SMILES
O=C1C2=CC=C(C(N)=C2C(N1C3C(NC(CC3)=O)=O)=O)OC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)