PROTAC STAT6 degrader-3
Based on 1 Customer Validation
PROTAC STAT6 degrader-3 is a potent STAT6 PROTAC degrader with a DC50 of less than 1 nM. PROTAC STAT6 degrader-3 can be used for research on allergic/inflammatory diseases and cancer.
For research use only. We do not sell to patients.
- Purity: 98.66%
- CAS No.: 3077385-98-6
- Formula: C44H45F4N9O5
- Molecular Weight:855.88
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All PROTACs Isoforms
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Biological Activity
Chemical Information
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CAS No. 3077385-98-6
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Appearance Solid
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Molecular Weight 855.88
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Formula C44H45F4N9O5
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Color White to off-white
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SMILES
O=C(N(C)C)C(N1)=CC2=C1C(F)=C(C3=CCCN(C(CCN4N=CC=C4)=O)C3)C=C2C5=C(F)C(F)=C(N6CCN(C7=C(F)C=C(NC8CCC(NC8=O)=O)C(OC)=C7)CC6)C=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (58.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1684 mL | 5.8419 mL | 11.6839 mL | 29.2097 mL |
| 5 mM | 0.2337 mL | 1.1684 mL | 2.3368 mL | 5.8419 mL | |
| 10 mM | 0.1168 mL | 0.5842 mL | 1.1684 mL | 2.9210 mL | |
| 15 mM | 0.0779 mL | 0.3895 mL | 0.7789 mL | 1.9473 mL | |
| 20 mM | 0.0584 mL | 0.2921 mL | 0.5842 mL | 1.4605 mL | |
| 25 mM | 0.0467 mL | 0.2337 mL | 0.4674 mL | 1.1684 mL | |
| 30 mM | 0.0389 mL | 0.1947 mL | 0.3895 mL | 0.9737 mL | |
| 40 mM | 0.0292 mL | 0.1460 mL | 0.2921 mL | 0.7302 mL | |
| 50 mM | 0.0234 mL | 0.1168 mL | 0.2337 mL | 0.5842 mL |