10819 Results for "

rat conditioned taste aversion

" in MedChemExpress (MCE) Product Catalog:
Products (10819)

10819 Results for "rat conditioned taste aversion" in MCE Product Catalog:

21
21 Cited Publications
Cat. No.: HY-16210
CAS No.: 209799-67-7
Synonyms: BCX-1777; Immucillin-H
Research Areas:  

Cancer

Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels .
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20
20 Cited Publications
Cat. No.: HY-A0119
CAS No.: 13755-38-9
Synonyms: Sodium nitroprusside dihydrate; Sodium Nitroferricyanide(III) Dihydrate
Target:  

Autophagy

Research Areas:  

Cardiovascular Disease Cancer

Nitroprusside disodium dehydrate (Sodium nitroprusside dihydrate) is a vasodilator that available for the research of acute hypertension, heart failure. Nitroprusside disodium dehydrate induces autophagy in glutathione-depleted osteoblasts. Nitroprusside disodium dehydrate acts as a nitric oxide (NO) donor in a rat intestinal ischemia reperfusion model .
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19
19 Cited Publications
Cat. No.: HY-R04602
Target:  

MicroRNA

Research Areas:  

Cancer

MicroRNA Mimic Negative Control is a miRNA mimic of 21-nucleotides, and can be used as a negative control. The sequence of MicroRNA Mimic Negative Control is derived from cel-mir-239b. It has minimal sequence identity with miRNAs in human, mouse, and rat.
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17
17 Cited Publications
Cat. No.: HY-50697
CAS No.: 861393-28-4
Target:  

P2X Receptor

Research Areas:  

Neurological Disease

A-740003 is a potent, selective and competitive P2X7 receptor antagonist with IC50 values are 18 and 40 nM for rat and human P2X7 receptors, respectively.
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17
17 Cited Publications
Cat. No.: HY-14595
CAS No.: 491-80-5
Purity:  99.29%
Synonyms: 4-Methylgenistein; Olmelin
Biochanin A is a naturally occurring fatty acid amide hydrolase (FAAH) inhibitor, which inhibits FAAH with IC50s of 1.8, 1.4 and 2.4 μM for mouse, rat, and human FAAH, respectively.
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16
16 Cited Publications
Cat. No.: HY-108463
CAS No.: 1170613-55-4
Purity:  99.30%
Target:  

TRP Channel

A-967079 is a selective TRPA1 receptor antagonist with IC50s of 67 nM and 289 nM at human and rat TRPA1 receptors, respectively, and has good penetration into the blood-brain barrier .
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15
15 Cited Publications
Cat. No.: HY-130246
CAS No.: 2380230-73-7
Purity:  99.92%
Target:  

Succinate Receptor 1

Research Areas:  

Inflammation/Immunology

NF-56-EJ40 is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM .
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15
15 Cited Publications
Cat. No.: HY-130246A
CAS No.: 2728500-80-7
Target:  

Succinate Receptor 1

Research Areas:  

Inflammation/Immunology

NF-56-EJ40 hydrochloride is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 hydrochloride has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM .
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15
15 Cited Publications
Cat. No.: HY-14394
CAS No.: 17374-26-4
Purity:  98.54%
Synonyms: NSC 231634; Casein Kinase II Inhibitor I
Target:  

Casein Kinase

Research Areas:  

Cancer

TBB is a cell-permeable and ATP-competitive CK2 inhibitor with an IC50 of 0.15 μM for rat liver CK2.
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15
15 Cited Publications
Cat. No.: HY-P1010
CAS No.: 210345-04-3
Target:  

Caspase Apoptosis

Research Areas:  

Neurological Disease Cancer

Z-LEHD-FMK is a selective and irreversible inhibitor of caspase-9, protects against lethal reperfusion injury and attenuates apoptosis. Z-LEHD-FMK exhibits the neuroprotective effect in a rat model of spinal cord trauma .
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15
15 Cited Publications
Cat. No.: HY-P7116A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BDNF; Abrineurin; Brain Derived Neurotrophic Factor; Brain-Derived Neurotrophic Factor Preproprotein Isoform 2; ProBDNF; Brain-Derived Neurotrophic Factor Isoform 1; Neurotrophic Factor BDNF Precursor Form; ANON2; Brain-Derived Neurotrophic Factor; BULN2
Species:  
Mouse Rat Human
Source:  
E. coli
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14
14 Cited Publications
Cat. No.: HY-111341
CAS No.: 618913-30-7
Purity:  99.93%
Research Areas:  

Neurological Disease

AZD5904 is a selective and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat.
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14
14 Cited Publications
Cat. No.: HY-108682
CAS No.: 680590-49-2
Purity:  99.92%
Research Areas:  

Neurological Disease

EMPA is a high-affinity, reversible and selective orexin OX2 receptor antagonist. [ 3H]EMPA binds to human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively .
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14
14 Cited Publications
Cat. No.: HY-B0199A
CAS No.: 116680-01-4
Synonyms: RS 61443 hydrochloride; TM-MMF hydrochloride
Mycophenolate mofetil (RS 61443; TM-MMF) hydrochloride is an orally active antimetabolic immunosuppressant with antiproliferative and anti-inflammatory properties. Mycophenolate mofetil hydrochloride significantly inhibits the production of B, T lymphocytes and the proliferation of smooth muscle cells by selectively blocking the de novo purine synthesis pathway. Mycophenolate mofetil hydrochloride effectively reduces adventitial inflammation, medial necrosis and intimal thickening in rat aortic allografts, and decreases the number of lymphocytes expressing the IL-2 receptor, thereby delaying xenograft rejection. Mycophenolate mofetil hydrochloride shows certain toxicity in a hamster-to-rat limb xenotransplantation model when used in combination with FK506 (HY-13756). Mycophenolate mofetil hydrochloride is widely used in studies related to allograft arteriosclerosis (chronic rejection) .
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14
14 Cited Publications
Cat. No.: HY-RI04602
Target:  

MicroRNA

Research Areas:  

Others

MicroRNA Inhibitor Negative Control is a full-length nucleotide 2'-methoxy modified oligonucleotide, and can be used as a negative control. The sequence of MicroRNA Inhibitor Negative Control is derived from cel-mir-239b. It has minimal sequence identity with miRNAs in human, mouse, and rat.
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14
14 Cited Publications
Cat. No.: HY-13104
CAS No.: 711019-86-2
Purity:  98.15%
Target:  

P2Y Receptor Apoptosis

Research Areas:  

Cardiovascular Disease

MRS 2578 is a selective and potent P2Y6 receptor antagonist with IC50s of 37 nM (human) and 98 nM (rat). MRS 2578 exhibits insignificant activity at P2Y1, P2Y2, P2Y4, and P2Y11 receptors .
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14
14 Cited Publications
Cat. No.: HY-13290
CAS No.: 127191-97-3
Purity:  99.45%
Target:  

CaMK P2X Receptor

Research Areas:  

Metabolic Disease Cancer

KN-62 is a selective and reversible inhibitor of calmodulin-dependent protein kinase II (CaMK-II) with a Ki of 0.9 μM for rat brain CaMK-II. KN-62 directly binds to the calmodulin binding site of CaMK-II. KN-62 displays noncompetitive antagonism at P2X7 receptors in HEK293 cells, with an IC50 value of approximately 15 nM.
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13
13 Cited Publications
Cat. No.: HY-106224
CAS No.: 205640-90-0
Purity:  99.93%
Synonyms: Hypocretin-1 (human, rat, mouse)
Research Areas:  

Neurological Disease

Orexin A (human, rat, mouse) (Hypocretin-1 (human, rat, mouse)), a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. Orexin A (human, rat, mouse) binds and activates two types of G protein-coupled receptors, the orexin-1 receptor (OX1R) and the orexin-2 receptor (OX2R). Orexin A (human, rat, mouse) has a role in the regulation of feeding behavior. Orexin A (human, rat, mouse) is an effective anti-nociceptive and anti-hyperalgesic agent in mice and rats .
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13
13 Cited Publications
Cat. No.: HY-106224A
Purity:  97.13%
Synonyms: Hypocretin-1 (human, rat, mouse) TFA
Research Areas:  

Neurological Disease

Orexin A (human, rat, mouse) (Hypocretin-1 (human, rat, mouse)) TFA, a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. Orexin A (human, rat, mouse) TFA binds and activates two types of G protein-coupled receptors, the orexin-1 receptor (OX1R) and the orexin-2 receptor (OX2R). Orexin A (human, rat, mouse) TFA has a role in the regulation of feeding behavior. Orexin A (human, rat, mouse) TFA is an effective anti-nociceptive and anti-hyperalgesic agent in mice and rats .
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13
13 Cited Publications
Cat. No.: HY-106224B
Purity:  99.93%
Synonyms: Hypocretin-1 (human, rat, mouse) acetate
Research Areas:  

Neurological Disease

Orexin A (Hypocretin-1) (human, rat, mouse) acetate is a hypothalamic neuropeptide with analgesic properties (crosses the blood-brain barrier). Orexin A (human, rat, mouse) acetate binds and activates two types of G protein-coupled receptors, the orexin-1 receptor (OX1R) and the orexin-2 receptor (OX2R). Orexin A (human, rat, mouse) acetate can be used in studies of appetite regulation, neurodegenerative diseases and modulation of injurious messaging .
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