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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10652 Results for "
WERI-Rb1 cells
" in MedChemExpress (MCE) Product Catalog:
Products (10652)
10652 Results for "WERI-Rb1 cells" in MCE Product Catalog:
156
156 Cited Publications
Synonyms: Streptozocin; NSC-85998; U 9889
149
149 Cited Publications
Synonyms: N-Acetyl-5-methoxytryptamine
138
138 Cited Publications
Referencia número: HY-W090090
No. CAS: 121207-31-6
Synonyms: Pyrromethene 546
135
127
126
126 Cited Publications
Referencia número: HY-D0938
No. CAS: 150347-59-4
Synonyms: CFSE; 5(6)-CaRboxyfluorescein diacetate succinimidyl ester; 5(6)-CFDA N-succinmidyl ester
126
126 Cited Publications
Synonyms: RAD001; SDZ-RAD
Áreas de investigación:
Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective, orally active, blood-brain barrier-permeable mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities [1] .
124
124
117
117 Cited Publications
Target:
Áreas de investigación:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
PX-478 is a multifunctional HIF-1α inhibitor with properties including radiosensitization, autophagy activation, and lipid accumulation inhibition. PX-478 also blocks hypoxia-induced VEGF production and regulates β-cell phenotypes under hypoxic conditions. PX-478 induces cell cycle arrest and DNA damage, restores autophagic function, reduces foam cell formation, and maintains glucose homeostasis. PX-478 is widely used in research on related diseases such as human tumors (e.g., prostate cancer), type 2 diabetes, and atherosclerosis [1] .
115
115 Cited Publications
Target:
Áreas de investigación:
S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor with a Kd of 0.19 nM for human MCL1 [1].
114
114 Cited Publications
Synonyms: BIBW 2992
Afatinib (BIBW 2992) is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR wt, EGFR L858R, EGFR L858R/T790M and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer [1] .
114
114 Cited Publications
Synonyms: BIBW 2992MA2
Afatinib (BIBW 2992) dimaleate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR wt, EGFR L858R, EGFR L858R/T790M and HER2, respectively. Afatinib dimaleate can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer [1] .
108
Category:
Disease Research Antibacterial Other Antibiotics Microorganisms Plant Cell Culture Antibiotics Phenols Polyphenols Disease Research Fields Cancer
Target:
108
108
108
106
106 Cited Publications
Synonyms: Cytosine β-D-arabinofuranoside hydrochloride; Cytosine Arabinoside hydrochloride; Ara-C hydrochloride
Cytarabine hydrochloride, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine hydrochloride has antiviral effects against HSV.
105
105 Cited Publications
Synonyms: Pifithrin hydrobromide; PFTα hydrobromide
Áreas de investigación:
Pifithrin-α hydrobromide is a p53 inhibitor which blocks its transcriptional activity and prevents cells from apoptosis. Pifithrin-α hydrobromide is also an aryl hydrocarbon receptor (AhR) agonist.
104
104 Cited Publications
Referencia número: HY-N6682
No. CAS: 22144-77-0
Synonyms: Zygosporin A; NSC 209835
Target:
-
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
