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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10652 Results for "
WERI-Rb1 cells
" in MedChemExpress (MCE) Product Catalog:
Products (10652)
10652 Results for "WERI-Rb1 cells" in MCE Product Catalog:
103
103 Cited Publications
Target:
Forschungsgebiete:
Dynasore is a cell-permeable dynamin inhibitor with an IC50 of 15 μM. Dynasore blocks cell migration.
102
102 Cited Publications
Art. -Nr.: HY-K1006
MCE Penicillin-Streptomycin (100×), Sterile is used to prevent bacterial contamination of cell culture due to their effective combined action against gram-positive and gram-negative bacteria, which contains 10,000 units/mL of penicillin and 10 mg/mL of streptomycin.
100
100 Cited Publications
Art. -Nr.: HY-128868
CAS. Nr.: 60842-46-8
100
100 Cited Publications
Art. -Nr.: HY-128868A
CAS. Nr.: 60842-46-8
99
Target:
Forschungsgebiete:
4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 [1].
99
Forschungsgebiete:
Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent.
97
Target:
Forschungsgebiete:
Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities [1] .
96
96 Cited Publications
Art. -Nr.: HY-W303895
CAS. Nr.: 6113-16-2
Luteolin (monohydrate) is the monohydrate of Luteolin. Luteolin (Luteoline), a flavonoid, is also a potent Nrf2 inhibitor. Luteolin has anti-inflammatory and anticancer properties, induces apoptosis and cell cycle arrest in multiple human cancer cell lines, including non-small lung cancer cells, and inhibits cell metastasis and angiogenesis [1].
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96 Cited Publications
Synonyms: Luteoline; Luteolol; Digitoflavone
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96 Cited Publications
Synonyms: E64d; E64c ethyl ester
Forschungsgebiete:
Aloxistatin (E64d) is a cell-permeable and irreversible broad-spectrum cysteine protease inhibitor. Aloxistatin (E64d) exhibits entry-blocking effect for MERS-CoV.
94
Category:
Anti-aging Leguminosae Extract Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Microorganisms Glycine max (L.) merr Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer Isoflavones
Target:
93
93 Cited Publications
Art. -Nr.: HY-K0206
MCE Anti-c-Myc Magnetic Beads are used for immunoprecipitation (IP) of specific c-Myc-tagged proteins expressed in bacterial and mammalian cells and in vitro expression systems. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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92 Cited Publications
Art. -Nr.: HY-D0041
CAS. Nr.: 148504-34-1
Synonyms: Calcein acetoxymethyl ester
90
90 Cited Publications
Synonyms: LBH589; NVP-LBH589; MTX 110
Panobinostat (LBH589; NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities [1] . Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells . Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma .
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89 Cited Publications
Art. -Nr.: HY-K1073
MCE Annexin V-FITC/PI Apoptosis Detection Kit provides a rapid and convenient method to detect cell apoptosis and necrosis. After staining, live cells show little or no fluorescence (Annexin V-/PI-), early apoptosis cells show green fluorescence(Annexin V+/PI-), late apoptosis cells and necrosis cells show red and green fluorescence (Annexin V+/PI+).
88
88 Cited Publications
Synonyms: Amethopterin hydrate; CL14377 hydrate; WR19039 hydrate
Methotrexate hydrate (Amethopterin hydrate; CL14377 hydrate; WR19039 hydrate) is an orally active antifolate (Antifolate). Methotrexate hydrate inhibits dihydrofolate reductase (DHFR), blocks tetrahydrofolate production, suppresses purine/pyrimidine synthesis and transmethylation, and causes intracellular accumulation of AICAR. Methotrexate hydrate promotes extracellular adenosine release, regulates the cytokine network, and inhibits the alarmin function of HMGB1. Methotrexate hydrate induces apoptosis and cytotoxicity, upregulates the expression of iNOS and COX-2, suppresses hippocampal neurogenesis, and induces pulmonary fibrosis. Methotrexate hydrate is used in the research of various immune and inflammation-related diseases such as arthritis, psoriasis, systemic lupus erythematosus, as well as pulmonary fibrosis and breast cancer [1] .
88
88 Cited Publications
Synonyms: Dimethyloxallyl Glycine
Target:
Forschungsgebiete:
DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1α stabilisation and accmulation in vitro and in vivo [1]. DMOG is an α-ketoglutarate analogue and inhibits α-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal . DMOG induces cell autophagy .
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87 Cited Publications
Art. -Nr.: HY-D0985A
CAS. Nr.: 115532-52-0
Synonyms: Tetramethylrhodamine ethyl ester perchlorate
87
87 Cited Publications
Synonyms: BrdU; 5-Bromo-2'-deoxyuridine; Bromodeoxyuridine
Forschungsgebiete:
5-BrdU (BrdU) is a nucleoside analog that competes with thymidine for incorporation into DNA. 5-BrdU is commonly used in the detection of proliferating cells.
85
85 Cited Publications
Synonyms: Kempferol; Robigenin
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
