918 Results for "

N2

" in MedChemExpress (MCE) Product Catalog:
Products (918)

918 Results for "N2" in MCE Product Catalog:

Cat. No.: HY-N17963
CAS No.: 229483-41-4
Cappariloside A is a larvicide that exhibits larvicidal activity against Aedes aegypti larvae and reduces larval glutathione-S-transferase activity. Cappariloside A also possesses antiviral activity, decreases the level of phosphorylated STAT1 in cells, inhibits the replication of influenza viruses H1N1, H3N2, PIV3 and ADV, and downregulates the expression of IL-6, IP-10, MIG, RANTES/CCL-5, IFN-β and IL-29. Cappariloside A suppresses the inflammatory response induced by mouse lung-adapted influenza virus strains. Cappariloside A can be used in studies related to larvicidal applications and influenza virus infection [2].
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Cat. No.: HY-Y1010
CAS No.: 556-52-5
Synonyms: Glycidol
Target:  

Drug Isomer

Research Areas:  

Cancer

Oxiran-2-ylmethanol (Glycidol) is an ester product. Oxiran-2-ylmethanol induces base pair point mutations in bacterial strains and structural chromosome aberrations in cultured cells. Oxiran-2-ylmethanol forms N-(2,3-dihydroxypropyl)valine hemoglobin adducts. Oxiran-2-ylmethanol acts as an animal carcinogen but does not significantly induce micronucleated immature erythrocytes in animal bone marrow. Oxiran-2-ylmethanol enables anionic polymerization to produce linear poly(glycidol). Oxiran-2-ylmethanol can be used for cancer-related research [2] .
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Cat. No.: HY-P71816
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DPYSL2; ULIP-2; Dihydropyrimidinase Like 2; ULIP2; DRP-2; N2A3; CRMP2; Collapsin Response Mediator Protein HCRMP-2; Dihydropyrimidinase-Related Protein 2; Collapsin Response Mediator Protein 2; DHPRP2; Dihydropyrimidinase-Like 2 Short Form; DRP2; Dihydrop
Species:  
Human
Source:  
P. pastoris
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Cat. No.: HY-103658R
CAS No.: 15809-19-5
Synonyms: Miramistin (Standard)
Myramistin (Miramistin) (Standard) is the analytical standard of Myramistin (HY-103658). This product is intended for research and analytical applications. Myramistin is a cationic surfactant and disinfectant preservative. Myramistin exhibits high bactericidal activity against Staphylococcus aureus and Escherichia coli, shows lower activity against yeasts and fungi, and is active against HIV, measles virus, mumps virus, as well as influenza viruses of the H3N2 and H5N1 subtypes. Myramistin adsorbs to the negatively charged microbial cell membrane, leading to increased membrane permeability and disruption of membrane integrity, which ultimately results in leakage of intracellular contents, enzyme inactivation, and the death of bacteria/fungi/enveloped viruses [2] .
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Cat. No.: HY-136820S1
Taurultam-d2 hydrochloride is the d2-labeled Taurultam (HY-136820) hydrochloride. Taurultam is the major active hydrolytic metabolite of Taurolidine (HY-W011522), which selectively activates hTRPA1 to trigger effects in sensory neurons. Taurultam exhibits activity against SARS-CoV-2 variants, influenza A viruses (H1N1, H3N2) and influenza B viruses. Taurultam induces mild tracheal sensory nerve stimulation and CGRP release in mice. Taurultam can be used in studies related to SARS-CoV-2 infection, influenza virus infection, and co-infection with SARS-CoV-2 and influenza A virus. [2]
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Cat. No.: HY-143494
CAS No.: 2395007-81-3
Target:  

RSV Influenza Virus

Research Areas:  

Infection

RSV/IAV-IN-3 (compound 14'i) is a dual inhibitor of respiratory syncytial virus (RSV) and influenza A virus (IAV) with EC50 values of 2.92 µM and 1.90 µM,respectively. RSV/IAV-IN-3 has antiviral effect against H1N1 and H3N2 with EC50 values of 3.25 µM and 1.50 µM in MDCK cells, respectively. RSV/IAV-IN-3 significantly inhibits the activity of luciferase in a dose-dependent manner, with an EC50 of 3.89 µM. RSV/IAV-IN-3 inhibits IAV infectivity and RdRp activity. RSV/IAV-IN-3 inhibits IAV and RSV replication at the post-entry stage .
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Cat. No.: HY-N0638R
CAS No.: 2115-91-5
Dendrobine (Standard) is the analytical standard of Dendrobine. This product is intended for research and analytical applications. Dendrobine is an alkaloid isolated from Dendrobium nobile. Dendrobine possesses antiviral activity against influenza A viruses, with IC50s of 3.39 μM, 2.16 μM and 5.32 μM for A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1) and A/Aichi/2/68 (H3N2), respectively. Dendrobine activates the JNK/p38/Nrf2 signaling pathway. Dendrobine exhibits antiviral, antitumor, anti-inflammatory, and neuroprotective properties [2] .
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Cat. No.: HY-P702064
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UBE2L5; Ubiquitin Conjugating Enzyme E2 L5; UBE2L5P; Ubiquitin-Conjugating Enzyme E2 L5; Ubiquitin-Protein Ligase L5; Ubiquitin Conjugating Enzyme E2L 5 (Pseudogene); Ubiquitin Conjugating Enzyme E2 L5, Pseudogene; UBCH7N2
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P702066
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UBE2L5; Ubiquitin Conjugating Enzyme E2 L5; UBE2L5P; Ubiquitin-Conjugating Enzyme E2 L5; Ubiquitin-Protein Ligase L5; Ubiquitin Conjugating Enzyme E2L 5 (Pseudogene); Ubiquitin Conjugating Enzyme E2 L5, Pseudogene; UBCH7N2
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P5377
CAS No.: 221055-89-6
Synonyms: Cathepsin K substrate
Target:  

Ser/Thr Protease

Research Areas:  

Others

Abz-HPGGPQ-EDDnp (Cathepsin K substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin K is the lysosomal cysteine protease involved in bone remodeling and resorption. It has potential as a drug target in autoimmune diseases and osteoporosis.This FRET peptide can be used to monitor selectively cathepsin K activity in physiological fluids and cell lysates. Abz-HPGGPQ-EDDnp [where Abz represents o-aminobenzoic acid and EDDnp represents N -(2, 4-dinitrophenyl)-ethylenediamine], a substrate initially developed for trypanosomal enzymes, is efficiently cleaved at the Gly-Gly bond by cathepsin K. This peptide is resistant to hydrolysis by cathepsins B, F, H, L, S and V, Ex/Em=340 nm/420 nm.)
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Cat. No.: HY-P992482
VIR-2482 is a monoclonal antibody targeting influenza A hemagglutinin (HA). VIR-2482 is generated by introducing LS mutations (M428L/N434S) into the Fc region of MEDI8852 (HY-P991446). VIR-2482 binds to the conserved HA stem epitope across all 18 influenza A HA subtypes, neutralizes a broad spectrum of H1N1 and H3N2 strains, binds to FcγRIIIa, FcγRIIa and C1q, and induces antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. VIR-2482 reduces morbidity and mortality caused by seasonal influenza A strains and provides prophylactic protection in mice. VIR-2482 can be used in research related to influenza A disease [2] .
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Cat. No.: HY-Y1010R
CAS No.: 556-52-5
Synonyms: Glycidol (Standard)
Research Areas:  

Cancer

Oxiran-2-ylmethanol (Standard) is the analytical standard of Oxiran-2-ylmethanol (Glycidol) (HY-Y1010). This product is intended for research and analytical applications. Oxiran-2-ylmethanol is an ester product. Oxiran-2-ylmethanol induces base pair point mutations in bacterial strains and structural chromosome aberrations in cultured cells. Oxiran-2-ylmethanol forms N-(2,3-dihydroxypropyl)valine hemoglobin adducts. Oxiran-2-ylmethanol acts as an animal carcinogen but does not significantly induce micronucleated immature erythrocytes in animal bone marrow. Oxiran-2-ylmethanol enables anionic polymerization to produce linear poly(glycidol). Oxiran-2-ylmethanol can be used for cancer-related research [2] .
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Cat. No.: HY-Y1010S
CAS No.: 1246819-20-4
Synonyms: Glycidol-d5
Oxiran-2-ylmethanol-d5 is the deuterium labeled Oxiran-2-ylmethanol (Glycidol) (HY-Y1010). Oxiran-2-ylmethanol is an ester product. Oxiran-2-ylmethanol induces base pair point mutations in bacterial strains and structural chromosome aberrations in cultured cells. Oxiran-2-ylmethanol forms N-(2,3-dihydroxypropyl)valine hemoglobin adducts. Oxiran-2-ylmethanol acts as an animal carcinogen but does not significantly induce micronucleated immature erythrocytes in animal bone marrow. Oxiran-2-ylmethanol enables anionic polymerization to produce linear poly(glycidol). Oxiran-2-ylmethanol can be used for cancer-related research [2] .
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Cat. No.: HY-P77107
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NOTCH2NLA; Notch Homolog 2 (Drosophila) N-Terminal Like; Prev. NOTCH2NL; Notch Homolog 2 N-Terminal-Like Protein; N2N; Notch 2 N-Terminal Like; Notch Homolog 2 N-Terminal-Like Protein A; Notch 2 N-Terminal Like A; Notch Homolog 2 N-Terminal Like Protein
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P1837
CAS No.: 186302-15-8
Target:  

Influenza Virus HSV

Research Areas:  

Infection

Influenza HA (518-526) is an H-2d-restricted CTL epitope derived from influenza virus hemagglutinin. Influenza HA (518-526) is highly conserved across various H5N1, some H9N2, and H1N1 strains. Influenza HA (518-526) binds to the mouse MHC class I allele K d to form a complex, which is then recognized by specific CD8 + T cells. Influenza HA (518-526) is an immunodominant epitope in influenza-infected BALB/c mice, and it stimulates CD8 + T cells to secrete IFN-γ to induce a robust immune response. Currently, Influenza HA (518-526) is widely used in research related to respiratory syncytial virus (RSV), influenza virus, and H5N1 influenza [2] .
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Cat. No.: HY-N0440R
CAS No.: 6902-91-6
Germacrone (Standard) is an analytical standard of Gemmacrone (HY-N0440). This product is intended for research and analytical applications. Germacrone (Standard) is a sesquiterpene compound with multiple biological activities. Germacrone (Standard) inhibits the H1N1 and H3N2 influenza A viruses and the influenza B virus. Germacrone (Standard) blocks the progressionof arthritis by regulating Th1/Th2 balance and inhibiting NF-κB signaling. Germacrone (Standard) can arrest the cell cycle at G0/G1 and G2/M phases and induce apoptosis in breast cancer cells. Germacrone (Standard) inhibits 5α-reductase and has anti-androgenic effect. Germacrone (Standard) has neuroprotective functions and can be used for the study of traumatic brain injury (TBI). Germacrone (Standard) also has antioxidant activity [2] .
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Cat. No.: HY-189215
CAS No.: 3087067-85-1
Anti-Influenza agent 12 is an orally active inhibitor of influenza A virus infection. Anti-Influenza agent 12 inhibits RIG-I-mediated innate immune signaling and TLR3-mediated signaling pathways. Anti-Influenza agent 12 inhibits NF-κB phosphorylation and downregulates the expression levels of IRF3, ASC, iNOS, IL-4, IL-6, and IFN-α inflammatory genes. Anti-Influenza agent 12 inhibits viral nucleoprotein (NP) and matrix protein 2 (M2) mRNA transcription and protein synthesis. Anti-Influenza agent 12 inhibits virus-induced apoptosis, reduces ROS and NO production, and maintains mitochondrial membrane potential. Anti-Influenza agent 12 exhibits broad-spectrum activity against H1N1 and H3N2 subtypes, reduces viral load, and alleviates lung tissue damage. Anti-Influenza agent 12 can be used for research on influenza A virus infection .
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Cat. No.: HY-P706279
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ¹⁵N-Neuron-specific enolase; ¹⁵N-γ-Enolase; ¹⁵N-Enolase 2; ¹⁵N-2-Phosphoglycerate dehydratase; ENO2; Neural Enolase; Enolase 2; HEL-S-279; NSE; Epididymis Secretory Protein Li 279; 2-Phospho-D-Glycerate Hydro-Lyase; 2-Phospho-D-Glycerate Hydrolyase; Gamma-Enolase; Neuron Specific Gamma Enolase; Enolase 2 (Gamma, Neuronal); Phosphopyruvate Hydratase; Neuronal Enriched Enolase; Neurone-Specific Enolase; Neuron-Specific Enolase; Neuron Specific Enolase
Species:  
Human
Source:  
E. coli
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