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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
130 Results for "
subcutaneous fibrosarcoma
" in MedChemExpress (MCE) Product Catalog:
Products (130)
130 Results for "subcutaneous fibrosarcoma" in MCE Product Catalog:
Cat. No.: HY-W047478R
CAS No.: 4630-20-0
Synonyms: NSC 10154 (Standard)
Cat. No.: HY-W010480
CAS No.: 553-97-9
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Toluquinone is a Toluquinol analogue. Toluquinone shows lower growth inhibitory activity against a panel of cancer cell lines of breast adenocarcinoma, promyelocytic leukemia, glioblastoma, fibrosarcoma, and colorectal adenocarcinoma than Toluquinol .
Cat. No.: HY-182419
CAS No.: 904680-01-9
A-849519 is a reversible methionine aminopeptidase-2 (MetAP-2) inhibitor with an IC50 of 19 nM. A-849519 binds to the active site of the Mn 2+ form of human MetAP-2, where the oxygen atom of one acidic functional group interacts with the manganese ion, and another heteroatom binds to the water molecule above the two manganese ions, thereby functionally inhibiting enzyme activity. A-849519 inhibits the methionine processing activity of MetAP-2 as well as the proliferation of fibrosarcoma cells. A-849519 can be used in studies related to fibrosarcoma .
Cat. No.: HY-181447
CAS No.: 3104351-76-7
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GPX4 (S)-9i is a GPX4 inhibitor and ferroptosis inducer, with its (R) enantiomer exhibiting stronger activity. GPX4 (S)-9i can be used for the study of fibrosarcoma .
Cat. No.: HY-124922
CAS No.: 1197996-83-0
CBLC100 is an anticancer compound that targets FACT, while inhibiting NF-κB and activating p53. CBLC100 induces cytotoxicity through p53-dependent apoptotic and non-apoptotic pathways. CBLC100 is applicable to the research of cancers such as fibrosarcoma .
Cat. No.: HY-183232
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SRS6-11 is an iron death-independent necrotic cell death (Necrosis) inducer. SRS6-11 retains significant lethality in the presence of α-tocopherol (HY-W020044). SRS6-11 can be used in fibrosarcoma research .
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1-(3-Carboxypropyl)-3,7-dimethylxanthine is the major circulating oxidative carboxylation metabolite of Pentoxifylline (HY-B0715). 1-(3-Carboxypropyl)-3,7-dimethylxanthine protects fibrosarcoma cells against the cytotoxic effect of TNF-α .
Cat. No.: HY-109080R
CAS No.: 1446113-23-0
Synonyms: HM95573 (Standard); GDC-5573 (Standard); RG6185 (Standard)
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Belvarafenib (Standard) is the analytical standard of Belvarafenib (HY-109080). This product is intended for research and analytical applications. Belvarafenib (HM95573) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC50s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively .
Cat. No.: HY-N19737
CAS No.: 62560-99-0
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Alkaloids Annonaceae Extract Quinoline Alkaloids Plants Duguetia odorata (Diels) J.F.Macbr.
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Cat. No.: HY-125055A
CAS No.: 1417342-67-6
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CD08108 is a selective MC1R full agonist with an EC50 of 70 nM against hMC1R. CD08108 participates in the melanogenesis process. CD08108 promotes cell proliferation. CD08108 can be used in studies related to vitiligo, subcutaneous diseases and photosensitive diseases .
Cat. No.: HY-187736
CAS No.: 64420-40-2
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R34803 is an orally effective Microtubule inhibitor and antiparasitic agent. R34803 impedes directional migration by interfering with the cytoplasmic microtubule complex, and causes metaphase arrest to inhibit the growth of cancer cell aggregates while preventing their invasion into other tissues. R34803 exhibits activity against a variety of parasites. R34803 can be used for research on fibrosarcoma and helminthiasis .
Cat. No.: HY-127080
CAS No.: 97145-52-3
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Arbortristoside A is an orally active inhibitor of prostaglandin (prostaglandin), histamine (histamine) and serotonin (serotonin). Arbortristoside A mediates anti-inflammatory, analgesic, anti-allergic, immunomodulatory, antiviral and anti-ulcerogenic effects, and also exhibits in vitro anticancer activity. Arbortristoside A can be used in research related to human hepatocellular carcinoma, breast cancer, fibrosarcoma, leishmaniasis, allergic diseases, viral infections and gastric ulcers .
Cat. No.: HY-182719
CAS No.: 2374807-41-5
AZD0011, a prodrug of AZD0011-PL (HY-182718), is an orally active arginase 1 inhibitor with an IC50 of 328 nM. AZD0011 undergoes in vivo hydrolysis to release an arginase inhibitor payload, inhibiting arginine hydrolysis, increases arginine levels in plasma and the tumor microenvironment. AZD0011 restores innate immune function and inhibits tumor growth. AZD0011 can be used for the research of cancer, such as fibrosarcoma .
Cat. No.: HY-182400
CAS No.: 2201065-84-9
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AGI-25696 is an orally active ethionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 97 nM. AGI-25696 reduces intracellular SAM levels in cancer cells. AGI-25696 inhibits tumor growth in mice bearing subcutaneous KP4 MTAP-null pancreatic xenografts. AGI-25696 can be used for the research of mtap-deleted pancreatic cancer .
Cat. No.: HY-183340
CAS No.: 3023862-30-5
Antibacterial agent 341 is an anti-bacterial agent. Antibacterial agent 341 shows broad-spectrum Gram-positive antibacterial activity. Antibacterial agent 341 targets phosphatidylglycerol (PG) and cardiolipin (CL) in bacterial cell membranes, induces sustained depolarization of membranes, and disrupts the cell membrane integrity. Antibacterial agent 341 exhibits anti-infection activity against S. aureus-induced subcutaneous abscesses in mice .
Cat. No.: HY-P992453
Synonyms: MTBT1466A; RG-6315
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Cat. No.: HY-P10794
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Cat. No.: HY-P11618
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U-11634 is an orally active dopamine β-hydroxylase noncompetitive inhibitor, with rat LD50 values of 1197 mg/kg (subcutaneous) and 524 mg/kg (oral). U-11634 blocks conversion of dopamine to norepinephrine and reduces norepinephrine levels in brain. U-11634 decreases food intake and spontaneous motor activity via dietary inclusion. U-11634 induces thyroid toxicity and inhibits pregnancy. U-11634 inhibits deciduomata formation in intact and steroid-treated rats, with no reversal by progesterone or oestradiol. U-11634 can be used for pregnancy .
Cat. No.: HY-118973
CAS No.: 1807810-16-7
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LASSBio-1829 hydrochloride is an orally active IKK2 inhibitor with an IC50 of 3.8 μM against the human target (Sf21 cells). LASSBio-1829 hydrochloride blocks signal transduction of the inflammation-associated NF-κB activation pathway. LASSBio-1829 hydrochloride reduces leukocyte migration, TNF-α biosynthesis, ROS production and NO production. LASSBio-1829 hydrochloride exhibits anti-inflammatory activity in a carrageenan-induced subcutaneous air pouch mouse model. LASSBio-1829 hydrochloride alleviates licking behavior during the inflammatory phase of the mouse formalin test. LASSBio-1829 hydrochloride can be used in inflammation-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
