Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
197 Results for "
H2O2
" in MedChemExpress (MCE) Product Catalog:
Products (197)
197 Results for "H2O2" in MCE Product Catalog:
Cat. No.: HY-178141
Research Areas:
AChE/BuChE-IN-7 is a dual-action inhibitor with an IC50 valueof 0.15 μM for AChE and 0.7 μM for BuChE, SI of 4.7. AChE/BuChE-IN-7 shows anti-oxidant activity and can mitigate H2O2-induced cytotoxicity. AChE/BuChE-IN-7 has genomic stability and prolonged systemic availability. AChE/BuChE-IN-7 can be used for the research of neurological disease, such as Alzheimer's disease .
Cat. No.: HY-N13174
CAS No.: 1802175-67-2
Cat. No.: HY-172604
Research Areas:
Neuroprotective agent 10 is an orally active, blood-brain barrier permeable neuroprotective agent. Neuroprotective agent 10 scavenges ABTS, DPPH and superoxide anion free radicals. Neuroprotective agent 10 inhibits abnormal electrical discharges. At the cellular level, Neuroprotective agent 10 alleviates H2O2-induced oxidative damage and LPS (HY-D1056)-induced neuroinflammation, and relieves epileptic symptoms and oxidative damage in mice. Neuroprotective agent 10 can be used in the research of epilepsy .
Cat. No.: HY-15914
CAS No.: 54970-72-8
Synonyms: DCHBS
Target:
Research Areas:
DHBS (3, 5-dichloro-2-hydroxybenzenesulfonate) is used in conjunction with 4-aminoantipyrine (4-AAP) (HY-W100990) and hydrogen peroxide (H2O2) for chromogenic quantitation of peroxidase in coupled enzymatic reactions. Component of Trinder reagent for use with peroxidase to measure generation of hydrogen peroxide in automated systems .
Cat. No.: HY-178139
CAS No.: 3087062-50-5
Target:
Research Areas:
hMAO-B-IN-12 (Compound 6E) is a highly selective human monoamine oxidase B (hMAO-B) inhibitor (IC50=17.7 nM). hMAO-B-IN-12 reduces oxidative stress/lipid metabolism-derived products (e.g., H2O2). hMAO-B-IN-12 is promising for research of atherosclerosis .
Cat. No.: HY-D3139
CAS No.: 2245162-94-9
Cat. No.: HY-E70987
Target:
Research Areas:
Chloroperoxidase, Caldariomyces fumago (EC 1.11.1.10) is an extracellular heme glycoenzyme containing ferriprotoporphyrin IX as the prosthetic group. Chloroperoxidase, Caldariomyces fumago (EC 1.11.1.10) is a peroxide-dependent chlorinating enzyme. It also catalyzes peroxidase-, catalase-and cytochrome P450-type reactions of dehydrogenation, H2O2 decomposition and oxygen insertion, respectively.
Cat. No.: HY-N0025
CAS No.: 120406-34-0
Cat. No.: HY-W455884
CAS No.: 26281-43-6
Target:
Research Areas:
3,5-Dichloro-2-hydroxybenzenesulfonic acid is used in conjunction with Ampyrone (HY-B1398) (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantification of peroxidase in coupled enzymatic reactions. 3,5-Dichloro-2-hydroxybenzenesulfonic acid is used to measure hydrogen peroxide production in conjunction with peroxidase .
Cat. No.: HY-N3287
CAS No.: 83011-43-2
Cat. No.: HY-124834
CAS No.: 75483-04-4
Target:
Research Areas:
Nrf2 activator-10 (Compound AI-1) is a PI3K-dependent inducer for antioxidant response element (ARE) (EC50 is 2.7 μM) and an activator for Nrf2. Nrf2 activator-10 modifies Keap1, blocks Cul3-Keap1 ubiquitin ligase complex, activates the transcription of Nrf2. Nrf2 activator-10 protects cells from H2O2-induced apoptosis.
Cat. No.: HY-170925
Target:
Research Areas:
AChE-IN-81 (compound 22) is a potent, irreversible and selective AChE inhibitor. AChE-IN-81 inhibits activity on AChE with inhibitory rates of 80.0%, with an IC50 of 3.7 μM. AChE-IN-81 binds to AChE with a binding affinity (Kd) of 5.37 μM. AChE-IN-81 effectively reduces in zebrafish brain cells. AChE-IN-81 exhibits potential neuroprotective activities on H2O2-induced SH-SY5Y cell injury model .
Cat. No.: HY-W777959
CAS No.: 1329611-23-5
Cat. No.: HY-109110R
CAS No.: 435327-40-5
Synonyms: GC-4419 (Standard); M-40419 (Standard)
Research Areas:
Avasopasem manganese (Standard) is the analytical standard of Avasopasem manganese (HY-109110). This product is intended for research and analytical applications. Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O2*- to hydrogen peroxide (H2O2), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer .
Cat. No.: HY-P3263
CAS No.: 39346-34-4
Synonyms: L-Glutamate oxidase
Target:
Research Areas:
Glutamate oxidase (L-Glutamate oxidase) is a FAD-dependent oxidase with high substrate selectivity. Glutamate oxidase catalyzes the oxidative deamination of L-glutamate using O2 to produce α-ketoglutarate (α-KG), NH3, and H2O2. Glutamate oxidase is applicable to research related to the biocatalytic production of α-KG and the analytical detection of L-glutamate .
Cat. No.: HY-150563
CAS No.: 2361384-14-5
Target:
Research Areas:
Neuroinflammatory-IN-2 is a potent anti-neuroinflammatory agent with an IC50 value of 10.30 μM for MAO-B, and 96.33% inhibition of Aβ1-42 aggregation at 25 μM. Neuroinflammatory-IN-2 has neuroprotective activity in H2O2-induced PC-12 cell injury. Neuroinflammatory-IN-2 also has biometal chelating abilities, antioxidant activity, anti-neuroinflammatory activity and appropriate BBB permeability. Neuroinflammatory-IN-2 can be used for researching Alzheimer’s disease .
Cat. No.: HY-N0615R
CAS No.: 80418-24-2
Synonyms: Sanchinoside R1 (Standard); Sanqi glucoside R1 (Standard)
Category:
Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Extract Triterpenes Plant Terpenoids Araliaceae Extract
Target:
Cat. No.: HY-W423191
CAS No.: 534-42-9
Synonyms: 4-O-α-D-Glucopyranosyl-D-gluconic acid
Cat. No.: HY-159515
Research Areas:
PBE-AMF is a prodrug that activates H2O2 with anticancer activity. PBE-AMF impedes tumor proliferation by inhibiting DNA synthesis, reducing ATP levels, inducing apoptosis, and arresting the cell cycle. PBE-AMF potently and selectively inhibits the proliferation of MDA-MB-231 cells (IC50=6.4 μM) while sparing non-cancerous MCF-10A cells .
Cat. No.: HY-181176
Research Areas:
DEMAMP is an antioxidant. DEMAMP exhibits scavenging effects on DPPH and H2O2 free radicals, with IC50 values of 0.60 and 0.48 mg/mL, respectively. Molecular docking simulations show that DEMAMP potently inhibits NADPH oxidase and the Mpro and RdRp proteins of SARS-CoV-2, and ADMET analysis confirms that it has favorable oral bioavailability. DEMAMP can be used in studies related to COVID-19 .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
