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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
197 Results for "
H2O2
" in MedChemExpress (MCE) Product Catalog:
Products (197)
197 Results for "H2O2" in MCE Product Catalog:
Art. -Nr.: HY-E70385A
Target:
Forschungsgebiete:
Oxalate oxidase, B. subtilis (EC 1.2.3.4) is a redox enzyme that acts on the donor aldehyde or carbonyl group, using oxygen as the acceptor. Oxalate oxidase, B is involved in the metabolism of glyoxylate and dicarboxylic acids. Oxalate oxidase, B has two cofactors: FAD and manganese. Oxalate oxidase, B has three substrates: oxalic acid, O2, and H +, and two products: CO2 and H2O2.
Art. -Nr.: HY-E70926
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Lysine Oxidase, Trichoderma viride (EC 1.4.3.14), is an oxidoreductase that acts on the CH-NHsub>2 group in the donor molecule and uses oxygen as the acceptor. Lysine Oxidase participates in the degradation of lysine. The three substrates of lysine oxidase are L-lysine, O2, and H2O, while its three products are 6-amino-2-oxohexanoic acid, NH3, and H2O2.
Art. -Nr.: HY-N0501R
CAS. Nr.: 126105-11-1
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Sphingomyelin phosphodiesterase, Bacillus cereus is a sphingomyelin hydrolase and Insecticide. Sphingomyelin phosphodiesterase, Bacillus cereus catalyzes the decomposition of sphingomyelin into ceramide and phosphorylcholine. Sphingomyelin phosphodiesterase, Bacillus cereus causes rapid paralysis and death in injected insects, including German cockroaches and black cutworms. Sphingomyelin phosphodiesterase, Bacillus cereus reduces H2O2 production. Sphingomyelin phosphodiesterase, Bacillus cereus can be used in studies related to sepsis and endophthalmitis .
Art. -Nr.: HY-114809
CAS. Nr.: 126455-04-7
Forschungsgebiete:
AL-1 is a potent O2 - generation inhibitor (IC50 = 7.6 μM) through the inhibition of leukocytic NADPH oxidase. AL-1 inhibits 12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced H2O2 production. AL-1 reduces tumor incidence in ICR mouse skin. AL-1 can be used for research on oxidative stress-related diseases including cancer .
Art. -Nr.: HY-141712
CAS. Nr.: 2696407-32-4
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ZA18 is a selective TRPM2 channel inhibitor, with an IC50 value of 6.2 μM. ZA18 can effectively suppress intracellular Ca 2+ overload triggered by TRPM2 channel activation. ZA18 significantly reduce the mortality of SH-SY5Y cells induced by H2O2. ZA18 can be used for the study of ischemia-reperfusion injury, inflammation, or other neurodegenerative diseases .
Art. -Nr.: HY-141713
CAS. Nr.: 2696407-24-4
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ZA10 is a selective TRPM2 channel inhibitor, with an IC50 value of 8.1 μM. ZA10 can effectively suppress intracellular Ca 2+ overload triggered by TRPM2 channel activation. ZA10 significantly reduce the mortality of SH-SY5Y cells induced by H2O2. ZA10 can be used for the study of ischemia-reperfusion injury, inflammation, or other neurodegenerative diseases .
Art. -Nr.: HY-174460
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pCR8 is a CR8 prodrug and anticancer agent responsive to H2O2. pCR8 achieves selective release of CR8 via boronate ester oxidation mediated by elevated hydrogen peroxide levels at tumor sites, self-assembles into nanoparticles, and degrades cell cycle-related proteins. A synergistic effect is produced when pCR8 is used in combination with immune checkpoint inhibitors. pCR8 can be used for the research of triple-negative breast cancer .
Art. -Nr.: HY-W112021
CAS. Nr.: 3117-03-1
Synonyms: 2,5-Dimethoxybenzoquinone
Target:
Forschungsgebiete:
2,5-DMBQ (2,5-Dimethoxybenzoquinone) serves as an extracellular reductant. 2,5-DMBQ is involved in a crucial redox cycle, namely the extracellular hydroquinone-quinone redox cycle. In this cycle, 2,5-DMBQ is capable of reducing extracellular Fe ³⁺ and generating H2O2. 2,5-DMBQ plays a pivotal role in the biodegradation mechanism of brown rot fungal, assisting the fungi in decomposing and utilizing organic matter .
Art. -Nr.: HY-W112021R
CAS. Nr.: 3117-03-1
Synonyms: 2,5-Dimethoxybenzoquinone (Standard)
Forschungsgebiete:
2,5-DMBQ (2,5-Dimethoxybenzoquinone) serves as an extracellular reductant. 2,5-DMBQ is involved in a crucial redox cycle, namely the extracellular hydroquinone-quinone redox cycle. In this cycle, 2,5-DMBQ is capable of reducing extracellular Fe³⁺ and generating H2O2. 2,5-DMBQ plays a pivotal role in the biodegradation mechanism of brown rot fungal, assisting the fungi in decomposing and utilizing organic matter .
Art. -Nr.: HY-161783
CAS. Nr.: 3048532-05-1
Forschungsgebiete:
HDAC6-IN-45 (Compound 15) is a selective inhibitor for HDAC6 with IC50 of 15.2 nM. HDAC6-IN-45 exhibits neurotrophic through the upregulation of GAP43 and Beta-3 tubulin markers. HDAC6-IN-45 activates the Nrf2 signaling pathway, reduces H2O2-induced ROS production, inhibits apoptosis in PC12, and exhibits neuroprotective efficacy in SCOP-induced zebrafish Alzheimer's Disease models. HDAC6-IN-45 exhibits antioxidant activity and good blood-brain barrier (BBB) permeability .
Art. -Nr.: HY-P11474
Target:
Integrin FAK Akt ERK Interleukin Related TNF Receptor Bacterial Reactive Oxygen Species (ROS)
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Target:
Art. -Nr.: HY-162860
CAS. Nr.: 1030759-58-0
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FO-4-15 is an mGluR1/CaMKIIα activator. FO-4-15 has a protective effect against H2O2 in human neuroblastoma (SH-SY5Y) cells. FO-4-15 can improve cognitive impairment in Alzheimer’s disease mice by activating the mGluR1/CaMKIIα pathway, and can reduce Aβ accumulation, hyperphosphorylated Tau, and synaptic damage .
Art. -Nr.: HY-P5247
Synonyms: PTP20
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Art. -Nr.: HY-P5247A
Synonyms: PTP20 TFA
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Art. -Nr.: HY-119590
CAS. Nr.: 31501-55-0
Synonyms: Lonchocarpine
Art. -Nr.: HY-N20734
CAS. Nr.: 64527-08-8
Synonyms: Polygalacin
Target:
Art. -Nr.: HY-W587784
CAS. Nr.: 542-40-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
