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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10114 Results for "
biolipid function
" in MedChemExpress (MCE) Product Catalog:
Products (10114)
10114 Results for "biolipid function" in MCE Product Catalog:
5
5 Cited Publications
Synonyms: 5-Fluoro-2-indolyl deschlorohalopemide
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
FIPI is a phospholipase D (PLD) inhibitor with an IC50 for PLD1 and PLD2 of about 25 nM. FIPI regulates cytoskeletal recombination, cell diffusion and chemotaxis. FIPI can be used in cancer research. In addition, FIPI can enhance the secretion and aggregation of platelet dense particles, inhibit thrombosis, reduce ischemic stroke infarct volume and improve nerve function .
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5 Cited Publications
Cat. No.: HY-B1836A
CAS No.: 86426-17-7
Synonyms: MET-88 dihydrate; Quaterin dihydrate
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease
Meldonium (MET-88) dihydrate functions as a cardioprotective agent by cpmpetetively inhibiting γ-butyrobetaine hydroxylase (BBOX) and carnitine/organic cation transporter type 2 (OCTN2). Mildronate dihydrate exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Meldonium dihydrate is a fatty acid oxidation inhibitor .
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5 Cited Publications
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Research Areas:
Indacaterol is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. Indacaterol inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol can also be used in cardiovascular disease research .
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Indacaterol maleate (QAB149) is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. Indacaterol maleate inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol maleate can also be used in cardiovascular disease research .
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5 Cited Publications
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Research Areas:
HOIPIN-8 is a potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) with an IC50 of 11 nM. HOIPIN-8 is a HOIPIN-1 derivative with enhanced the potency by 255-fold in the petit-LUBAC inhibition, and 10-fold and 4-fold in the LUBAC- and TNF-α-mediated NF-κB activation, respectively than HOIPIN-1. HOIPIN-1 is a promising tool to explore the cellular functions of LUBAC .
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5 Cited Publications
Cat. No.: HY-N2292
CAS No.: 151870-74-5
Category:
Natural Products Orchidaceae Extract Plants Anoectochilus Disease Research Fields Inflammation/Immunology
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5 Cited Publications
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Research Areas:
NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Tropisetron Hydrochloride (SDZ-ICS-930) is an effective neuroprotective agent that acts as a 5-HT3 receptor antagonist, a calmodulin inhibitor, and an α7-nAChRreceptor agonist, with an IC50 of 70.1 nM for the 5-HT3 receptor. Tropisetron Hydrochloride has anti-inflammatory properties and immune-regulating functions, effectively alleviating symptoms associated with chemotherapy and post-surgery. Tropisetron Hydrochloride reduces Ab (HY-P4867)-induced hippocampal neuroinflammation .
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5 Cited Publications
Synonyms: Monoaminoethyl phosphate; NSC 254167; O-Phosphoethanolamine
Category:
Natural Products Immune System Disorder Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
4
4 Cited Publications
Synonyms: 2-Carboxyethylamine; 3-Aminopropanoic acid
Category:
Human Gut Microbiota Metabolites Microorganisms Anti-aging Disease markers Metabolic Disease Endocrine diseases Amino acids Nervous System Disorder Endogenous metabolite Disease Research Fields
Target:
4
4 Cited Publications
Synonyms: MK-2866; GTX-024; Enobosarm
Target:
Ostarine (MK-2866) is a selective androgen receptor modulator (SARMs) that regulates cardiomyocyte function, improves bone healing, regulates uterine function, and influences muscle tissue metabolism .
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4 Cited Publications
Cat. No.: HY-P0002
CAS No.: 24305-27-9
Synonyms: Thyrotropin-releasing-hormone; TRH
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4 Cited Publications
Cat. No.: HY-P0002A
CAS No.: 120876-23-5
Synonyms: Thyrotropin-releasing-hormone acetate; TRH acetate
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Research Areas:
4
4 Cited Publications
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RA190, a bis-benzylidine piperidon, inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.
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4 Cited Publications
Cat. No.: HY-P1034
CAS No.: 106362-34-9
Synonyms: D-Ala-peptide T-amide; Adaptavir
Research Areas:
4
4 Cited Publications
Cat. No.: HY-P0073
CAS No.: 58569-55-4
Synonyms: Met-Enkephalin; Methionine enkephalin; Metenkefalin
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Research Areas:
4
4 Cited Publications
Synonyms: Dantron; Chrysazin; 1,8-Dihydroxyanthraquinone
Category:
Quinones Anthraquinones Samanea saman (Jacq.) Merr. Phenols Polyphenols Plants Disease Research Fields Cancer Labiatae Extract
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4 Cited Publications
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XTT (sodium) is used to assess cell viability as a function of redox potential. Actively respiring cells convert the water-soluble XTT to a water-soluble, orange colored formazan product.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
