Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
183 Results for "
NADP
" in MedChemExpress (MCE) Product Catalog:
Products (183)
183 Results for "NADP" in MCE Product Catalog:
Cat. No.: HY-P701862
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SPR; Sepiapterin Reductase (7,8-Dihydrobiopterin:NADP+ Oxidoreductase); Sepiapterin Reductase; Sepiapterin Reductase (L-Erythro-7,8-Dihydrobiopterin Forming); SDR38C1; Short Chain Dehydrogenase/Reductase Family 38C, Member 1
Species:
Human
Source:
E. coli
Cat. No.: HY-P702132
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: 7beta-hydroxysteroid dehydrogenase; EC:1.1.1.201; 7beta-HSDH; NADP-dependent 7beta-hydroxysteroid dehydrogenase; COLAER_02089
Species:
Others
Source:
E. coli
Cat. No.: HY-E71791
Target:
Research Areas:
3-Sulfolactaldehyde dehydrogenase (EC 1.2.1.97) is an oxidoreductase that can catalyze multiple reactions, including reaction 1: convert (2S)-3-sulfolactaldehyde, NADP + and H2O into (2S)-3-sulfolactate, NADPH and 2 H +; reaction 2: convert (2S)-3-sulfolactaldehyde, NAD + and H2O into (2S)-3-sulfolactate, NADH and 2 H +.
Cat. No.: HY-E71871
Target:
Research Areas:
4-Nitrocatechol 4-monooxygenase (EC 1.14.13.166) is an oxidoreductase that can catalyze multiple reactions, including reaction 1: convert 4-nitrocatechol, NADPH and O2 into 2-hydroxy-1,4-benzoquinone, nitrite, NADP + and H2O; reaction 2: convert 4-nitrocatechol, NADH and O2 into 2-hydroxy-1,4-benzoquinone, nitrite, NAD + and H2O.
Cat. No.: HY-P70283
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: G6PD; Glucose-6-Phosphate Dehydrogenase (NADP(+)); Glucose-6-Phosphate Dehydrogenase; Epididymis Secretory Sperm Binding Protein; Glucose-6-Phosphate 1-Dehydrogenase; CNSHA1; G6PD1
Species:
Human
Source:
HEK293
Cat. No.: HY-P701861
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SPR; Sepiapterin Reductase (7,8-Dihydrobiopterin:NADP+ Oxidoreductase); Sepiapterin Reductase; Sepiapterin Reductase (L-Erythro-7,8-Dihydrobiopterin Forming); SDR38C1; Short Chain Dehydrogenase/Reductase Family 38C, Member 1
Species:
Human
Source:
E. coli
Cat. No.: HY-182284
Target:
Reactive Oxygen Species (ROS) Apoptosis Bcl-2 Family Caspase SHMT Methylenetetrahydrofolate Dehydrogenase (MTHFD) Cytochrome P450
Research Areas:
Anticancer agent 310 is an antitumor agent. Anticancer agent 310 releases nitric oxide to induce mitochondrial ROS burst, triggers mitochondrial dysfunction and activates the Bax/Bcl-2-Cyt c-Caspase-9/Caspase-3 apoptotic pathway. Anticancer agent 310 also reduces the levels of SHMT2 and MTHFD2, decreases the ratios of NADPH/NADP + and GSH/GSSG, thereby disrupting redox homeostasis and exacerbating intracellular ROS accumulation. Anticancer agent 310 can be used in research related to gastric cancer .
Cat. No.: HY-P87084
Synonyms: OTTHUMP00000160199 antibody; SDR38C1 antibody; Sepiapterin reductase (7,8 dihydrobiopterin:NADP+ oxidoreductase) antibody; Sepiapterin reductase antibody; Short chain dehydrogenase/reductase family 38C, member 1 antibody; SPR antibody; SPRE_HUMAN antibody;
Cat. No.: HY-16164
CAS No.: 57404-51-0
Target:
Research Areas:
DA-11004 is an orally active NADP-dependent isocitrate dehydrogenase (IDPc) inhibitor with an IC50 of 1.49 μM. DA-11004 reduces NADPH production, decreases plasma NADPH levels and plasma free fatty acid levels. DA-11004 lowers plasma glucose levels, inhibits fatty acid synthesis in adipose tissue, reduces weight gain and decreases epididymal and retroperitoneal fat content. DA-11004 exerts antidiabetic effects in mice fed a high-fat and high-sugar diet. DA-11004 can be used for research on obesity and type 2 diabetes .
Cat. No.: HY-E71865
Target:
Research Areas:
4-Methyl-5-nitrocatechol 5-monooxygenase (EC 1.14.13.210) is an oxidoreductase that can catalyze multiple reactions, including reaction 1: convert 4-methyl-5-nitrocatechol, NADPH and O2 into 2-hydroxy-5-methylquinone, nitrite, NADP +, H2O and H +; reaction 2: convert 4-methyl-5-nitrocatechol, NADH and O2 into 2-hydroxy-5-methylquinone, nitrite, NAD +, H2O and H +.
Cat. No.: HY-P72272
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CBR1; Carbonyl Reductase [NADPH] 1; Prev. CBR; Short Chain Dehydrogenase/Reductase Family 21C, Member 1; SDR21C1; 15-Hydroxyprostaglandin Dehydrogenase [NADP(+)]; Short Chain Dehydrogenase/Reductase Family 21C Member 1; Epididymis Secretory Sperm Binding Protein; 20-Beta-Hydroxysteroid Dehydrogenase; 15-Hydroxyprostaglandin Dehydrogenase; NADPH-Dependent Carbonyl Reductase 1; Carbonyl Reductase (NADPH) 1; Alcohol Dehydrogenase [NAD(P)+] CBR1; Carbonyl Reductase (NADPH); Prostaglandin-E(2) 9-Reductase; HCBR1; Prostaglandin 9-Ketoreductase; CRN; Carbonyl Reductase 1; PG-9-KR
Species:
Human
Source:
P. pastoris
Cat. No.: HY-165518
CAS No.: 128851-55-8
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
M 16287 is an orally active aldose reductase inhibitor, with an IC50 of 0.08 μM in rats and 0.25 μM in cattle. M 16287 improves lens fiber swelling and vacuolization, prevents galactitol accumulation, delays inositol depletion, inhibits glutathione reduction, restores the NADPH/NADP + ratio to normal, and normalizes lens Na + content and Na +/K + ratio. M 16287 prevents galactose-induced cataract formation in rats. M 16287 improves motor nerve conduction velocity in diabetic rats, partially alleviates histopathological changes in the sciatic nerve, and inhibits sorbitol accumulation. M 16287 can be used in studies related to cataracts and diabetic neuropathy .
Cat. No.: HY-175698
Research Areas:
Ferroptosis inducer-9 is a ferroptosis inducer and colchicine site tubulin polymerization inhibitor. Ferroptosis inducer-9 inhibits MCF-7 cell growth with an IC50 of 14 nM and inhibits [ 3H]colchicine binding. Ferroptosis inducer-9 reduces expression of GPX4 and FTH, increases COX2 and ACSL4, lowers GSH, NADP+, and NADPH levels, increases LPO, MDA, and Fe(II) levels, and decreases SOD concentrations. Ferroptosis inducer-9 demonstrates significant anti-tumor efficacy in HCT116 CRC xenograft model. Ferroptosis inducer-9 can be used for the study of triple negative breast cancer (TNBC) and colorectal cancer (CRC) .
Cat. No.: HY-E71860
Target:
Research Areas:
4-Hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) is an oxidoreductase that can catalyze multiple reactions, including reaction 1: convert (S)-2,3,4,5-tetrahydrodipicolinate, NAD + and H2O into (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate, NADH and H +; reaction 2: convert (S)-2,3,4,5-tetrahydrodipicolinate, NADP + and H2O into (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate, NADPH and H +.
Cat. No.: HY-P76871
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DHRS9; Dehydrogenase/Reductase (SDR Family) Member 9; Dehydrogenase/Reductase 9; Dehydrogenase/Reductase SDR Family Member 9; SDR9C4; Short-Chain Dehydrogenase/Reductase RetSDR8; RDH15; Retinol Dehydrogenase Homolog; RDHL; Retinol Dehydrogenase 15; NADP-D
Species:
Human
Source:
E. coli
Cat. No.: HY-P87310
Synonyms: 15-oxoprostaglandin 13-reductase antibody; FLJ99229 antibody; leukotriene B4 12-hydroxydehydrogenase antibody; LTB4DH antibody; MGC34943 antibody; NADP-dependent leukotriene B4 12-hydroxydehydrogenase antibody; PGR1 antibody; PRG-1 antibody; Prostaglandin reductase 1 antibody; Ptgr1 antibody
Cat. No.: HY-181542
Research Areas:
SG-55 is a selective, noncompetitive and orally active AKR1C3 inhibitor with an IC50 of 5 nM and a Ki of 10 nM. SG-55 shows >2000-fold selectivity for AKR1C3 over AKR1C1, AKR1C2, and AKR1C4 (> 10 μM). SG-55 increases the ratio of reduced/oxidized nicotinamide adenine dinucleotide phosphate (NADPH/NADP +), decreases the ratio of reduced/oxidized glutathione (GSH/GSSG), and induces DNA double-strand breaks. SG-55 can overcome Osimertinib (HY-15772) resistance mediated by EGFR C797S triple mutation in non-small cell lung cancer (NSCLC) .
Cat. No.: HY-P810355
Synonyms: decarboxylating, H105E3, H105e3 protein, NAD(P) dependent steroid dehydrogenase like, NSDHL, NSDHL_HUMAN, Protein H105e3, SDR31E1, Short chain dehydrogenase/reductase family 31E member 1, Sterol 4 alpha carboxylate 3 dehydrogenase decarboxylating
Cat. No.: HY-P7477
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ALDH3A1; Aldehyde Dehydrogenase 3 Family, Member A1; Prev. ALDH3; Aldehyde Dehydrogenase Type III; Aldehyde Dehydrogenase, Dimeric NADP-Preferring; Stomach Aldehyde Dehydrogenase; Aldehyde Dehydrogenase Family 3 Member A1; Aldehyde Dehydrogenase 3; ALDHII
Species:
Human
Source:
HEK293
Cat. No.: HY-P75568
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ALDH3A1; Aldehyde Dehydrogenase 3 Family, Member A1; Prev. ALDH3; Aldehyde Dehydrogenase Type III; Aldehyde Dehydrogenase, Dimeric NADP-Preferring; Stomach Aldehyde Dehydrogenase; Aldehyde Dehydrogenase Family 3 Member A1; Aldehyde Dehydrogenase 3; ALDHII
Species:
Human
Source:
Sf9 insect cells
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
