Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
157 Results for "
1-c][1
" in MedChemExpress (MCE) Product Catalog:
Products (157)
157 Results for "1-c][1" in MCE Product Catalog:
18
4
3
3 Cited Publications
Target:
Research Areas:
LFHP-1c is an PGAM5 inhibitor with neuroprotective activity in brain ischemic stroke. LFHP-1c protects blood-brain barrier integrity from ischemia-induced injury. LFHP-1c binds to endothelial PGAM5 to inhibit the activity of PGAM5 phosphatase and the interaction of PGAM5 with NRF2. LFHP-1c exhibits in vitro and in vivo protection .
3
3
3 Cited Publications
Cat. No.: HY-N12257
CAS No.: 27220-57-1
Category:
3
3 Cited Publications
Research Areas:
S07-2010 is a potent pan-AKR1C (aldo-keto reductase family 1 member C) inhibitor, with IC50 values of 0.19, 0.36, 0.47, and 0.73 μM for AKR1C3, AKR1C4, AKR1C1 and AKR1C2, respectively. S07-2010 induces apoptosis in A549/DDP cells. S07-2010 strengthens the cytotoxicity of chemotherapeutic agents in drug-resistant cells. S07-2010 significantly inhibits the proliferation of drug-resistant cells .
2
2 Cited Publications
Cat. No.: HY-P1925A
CAS No.: 1222186-26-6
Research Areas:
2
2 Cited Publications
Cat. No.: HY-D1341
CAS No.: 878019-47-7
Research Areas:
Coumberone is a metabolic fluorogenic probe, and isoform-selective substrate for all AKR1C isoforms. Coumberone can be reduced by all four members of the AKR1C family to its fluorescent alcohol coumberol. Coumberone can be used for the research of AKR1C .
2
2 Cited Publications
Cat. No.: HY-P7996
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPARA; HPPAR; Prev. PPAR; PPAR-Alpha; Peroxisome Proliferator-Activated Receptor Alpha; Alternative Protein PPARA; NR1C1; PPARalpha; Nuclear Receptor Subfamily 1 Group C Member 1; Peroxisome Proliferator Activated Receptor Alpha; Peroxisome Proliferative Activated Receptor, Alpha
Species:
Human
Source:
E. coli
2
2 Cited Publications
Target:
Research Areas:
GSK3987 is a pan LXRα/β agonist with EC50s of 50 nM, 40 nM for LXRα-SRC1 and LXRβ-SRC1, respectively. GSK3987 increases the expression of ABCA1 and SREBP-1c. GSK3987 induces cellular cholesterol efflux and triglyceride accumulation .
1
1
1 Cited Publications
Cat. No.: HY-P702843
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPARA; HPPAR; Prev. PPAR; PPAR-Alpha; Peroxisome Proliferator-Activated Receptor Alpha; Alternative Protein PPARA; NR1C1; PPARalpha; Nuclear Receptor Subfamily 1 Group C Member 1; Peroxisome Proliferator Activated Receptor Alpha; Peroxisome Proliferative
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P71718
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1QA; Complement Component 1, Q Subcomponent, A Chain; Complement C1q A Chain; Complement C1q Chain A; Complement C1q Subcomponent Subunit A; Complement Component C1q, A Chain; Complement Component 1, Q Subcomponent, Alpha Polypeptide; C1QD1
Species:
Mouse
Source:
P. pastoris
1
1 Cited Publications
Cat. No.: HY-P76185
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1QBP; Splicing Factor SF2-Associated Protein; Prev. HABP1; ASF/SF2-Associated Protein P32; Complement Component 1 Q Subcomponent-Binding Protein, Mitochondrial; Glycoprotein GC1qBP; Mitochondrial Matrix Protein P32; SF2AP32; Hyaluronan-Binding Protein 1
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-N4253
CAS No.: 173792-61-5
1
1 Cited Publications
Cat. No.: HY-N0853A
CAS No.: 18674-16-3
Synonyms: Alisol A 24-monoacetate; Alisol A monoacetate
1
1 Cited Publications
Cat. No.: HY-N2392
CAS No.: 75288-96-9
Cat. No.: HY-P990627
Synonyms: MEDI-547 antibody
Target:
Research Areas:
Cat. No.: HY-N2282
CAS No.: 91653-50-8
Synonyms: Zingiberensis newsaponin
Cat. No.: HY-107767
CAS No.: 81307-24-6
Synonyms: DC 81
Target:
Research Areas:
Antibiotic DC 81 (DC 81), an antitumor antibiotic produced by Streptomyces species, is a PBD (pyrrolo[2,1-c][1,4]benzodiazepine). Antibiotic DC 81 is potent inhibitor of nucleic acid synthesis. Antibiotic DC 81 can recognize and bind to specific sequences of DNA and form a labile covalent adduct .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
