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Results for "

ARP

" in MedChemExpress (MCE) Product Catalog:

18

Inhibitors & Agonists

1

Screening Libraries

1

Biochemical Assay Reagents

2

Peptides

15

Recombinant Proteins

26

Antibodies

4

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16926
    CK-666
    Maximum Cited Publications
    25 Publications Verification

    Arp2/3 Complex HIV Infection Cancer
    CK-666 is a cell-permeable actin-related protein Arp2/3 complex inhibitor (IC50=12 μM). CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation .
    CK-666
  • HY-16927
    CK-869
    3 Publications Verification

    Arp2/3 Complex Cancer
    CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor, with an IC50 of 7 μM.
    CK-869
  • HY-103444
    ARP-100
    1 Publications Verification

    MMP Cancer
    ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with S1' pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM) .
    ARP-100
  • HY-114657A
    Benproperine phosphate
    2 Publications Verification

    Arp2/3 Complex Inflammation/Immunology Cancer
    Benproperine phosphate is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate has the potential for a cough suppressant and suppresses cancer cell migration and tumor metastasis .
    Benproperine phosphate
  • HY-15892
    CK-636
    4 Publications Verification

    CK-0944636

    Arp2/3 Complex Inflammation/Immunology Cancer
    CK-636 is a cell permeable inhibitor of Arp2/3 complex, that could inhibit actin polymerization, with IC50 values of 4 μM, 24 μM and 32 μM for human, fission yeast and bovine, respectively. CK636 blocks cell migration.
    CK-636
  • HY-12534
    Wiskostatin
    2 Publications Verification

    Arp2/3 Complex Neurological Disease
    Wiskostatin is a potent and selective inhibitor of neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin polymerization by stabilization of the closed, autoinhibited conformation, thereby preventing Arp2/3 complex activation. Wiskostatin is also a dynamin inhibitor with an IC50 value of 20.7 μM and a potent inhibitor of clathrin-mediated endocytosis with an IC50 value of 6.9 μM. Wiskostatin causes a rapid, profound, and irreversible decrease in cellular ATP levels. Wiskostatin also induces disassembly of podosomes in a murine monocyte cell line .
    Wiskostatin
  • HY-101535
    ARP101
    1 Publications Verification

    Atg8/LC3 MMP Cancer
    ARP101 is a potent and selective inhibitor matrix metalloproteinase-2 (MMP-2). ARP101 induces autophagy-associated cell death in cancer cells. ARP101 is effective in inducing the formation of autophagosome and conversion of LC3I into LC3II .
    ARP101
  • HY-157916

    Aldehyde reactive probe

    Fluorescent Dye Others
    ARP (Aldehyde reactive probe) is an aldehyde-reactive probe . ARP specifically labels AP sites in DNA with biotin residues . ARP detects abasic sites induced by RNA oxidation . ARP is suitable for studies involving the quantification of AP sites, or the detection of other aldehyde-containing DNA damages and abasic sites induced by RNA oxidation .
    ARP
  • HY-123312

    CK-0993548

    Arp2/3 Complex HIV Infection
    CK-548 (CK-0993548) is a Arp2/3 complex inhibitor with the IC50 of 11 μM. CK-548 inhibits HIV-1 nuclear migration and infection .
    CK-548
  • HY-120213

    FAK Src PI3K MMP Apoptosis Cancer
    YH-306 is an antitumor agent. YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. YH-306 significantly inhibits the migration and invasion of colorectal cancer cells. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1 and the expression of MMP2 and MMP9. YH-306 also inhibita actin-related protein (Arp2/3) complex-mediated actin polymerization .
    YH-306
  • HY-RS08017

    Small Interfering RNA (siRNA) Others

    MANF Human Pre-designed siRNA Set A contains three designed siRNAs for MANF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MANF Human Pre-designed siRNA Set A
    MANF Human Pre-designed siRNA Set A
  • HY-P1045
    187-1, N-WASP inhibitor
    1 Publications Verification

    Arp2/3 Complex Others
    187-1, N-WASP inhibitor, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC50 of 2 μM. 187-1, N-WASP inhibitor prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein .
    187-1, N-WASP inhibitor
  • HY-103444R

    Reference Standards MMP Cancer
    ARP-100 (Standard) is the analytical standard of ARP-100. This product is intended for research and analytical applications. ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with S1' pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM) .
    ARP-100 (Standard)
  • HY-169385

    AUTOTACs Androgen Receptor Cancer
    ATC-324 is an bivalent AR (Androgen Receptor) degrader based on the protein degradation technology platform AUTOphagy-TArgeting Chimera (AUTOTAC). ATC-324 induces the formation of AR/p62 complex, leading to autophagy-lysosomal degradation of AR. ATC-324 can reduce nuclear AR levels and downregulate target gene expression of AR and AR-v7, and also has a degradation effect on common AR mutants in PCa . ATC-324 is composed of target-binding ligand (TBL) Enzalutamide (HY-70002) and p62/SQSTM1 autophagy-targeting ligand (ATL) YT 6-2 analog-1 (HY-169386), connected by Boc-NH-PEG4-CH2CH2NH2 (HY-W008352). Among them, the active control of the target protein ligand is Enzalutamide carboxylic acid (HY-70002B), and the conjugate composed of the autophagy-targeting ligand and the linker is YT 6-2-PEG3-C2-NH2 (HY-169387).
    ATC-324
  • HY-P1045A

    Arp2/3 Complex Others
    187-1, N-WASP inhibitor TFA, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor TFA potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC50 of 2 μM. 187-1, N-WASP inhibitor TFA prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein .
    187-1, N-WASP inhibitor TFA
  • HY-RS00906

    Small Interfering RNA (siRNA) Others

    ARFRP1 Human Pre-designed siRNA Set A contains three designed siRNAs for ARFRP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ARFRP1 Human Pre-designed siRNA Set A
    ARFRP1 Human Pre-designed siRNA Set A
  • HY-RS11848

    Small Interfering RNA (siRNA) Others

    RERE Human Pre-designed siRNA Set A contains three designed siRNAs for RERE gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    RERE Human Pre-designed siRNA Set A
    RERE Human Pre-designed siRNA Set A
  • HY-RS03179

    Small Interfering RNA (siRNA) Others

    CRISP1 Human Pre-designed siRNA Set A contains three designed siRNAs for CRISP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CRISP1 Human Pre-designed siRNA Set A
    CRISP1 Human Pre-designed siRNA Set A

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