403 Results for "

Aspergillus

" in MedChemExpress (MCE) Product Catalog:
Products (403)

403 Results for "Aspergillus" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-Y0337A
CAS No.: 52-89-1
L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) .
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8
8 Cited Publications
Cat. No.: HY-P2902
CAS No.: 9001-37-0
Research Areas:  

Cancer

Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation .
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5
5 Cited Publications
Cat. No.: HY-135849
CAS No.: 9001-05-2
Research Areas:  

Cancer

Catalase, Aspergillus niger is a key enzyme in the metabolism of H2O2 and reactive oxygen species (ROS), and its expression and localization is markedly altered in tumors . Free oxygen radical scavenger.
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4
4 Cited Publications
Cat. No.: HY-108009A
CAS No.: 1631754-41-0
Purity:  99.84%
Synonyms: Biafungin acetate; CD101 acetate; SP-3025 acetate
Target:  

Fungal

Research Areas:  

Infection

Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp. .
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4
4 Cited Publications
Cat. No.: HY-N6779
CAS No.: 149-29-1
Synonyms: Terinin
Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage .
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2
2 Cited Publications
Cat. No.: HY-101399
CAS No.: 7432-24-8
Purity:  99.82%
Synonyms: H-γ-Glu-Phe-OH; γ-Glutamylphenylalanine
γ-Glu-Phe is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .
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2
2 Cited Publications
Cat. No.: HY-101399A
CAS No.: 2828432-42-2
Purity:  99.50%
Synonyms: H-γ-Glu-Phe-OH TFA; γ-Glutamylphenylalanine TFA
γ-Glu-Phe TFA (γ-Glutamylphenylalanine TFA) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe TFA or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .
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2
2 Cited Publications
Cat. No.: HY-B1324
CAS No.: 64211-46-7
Synonyms: Ro 13-8996
Research Areas:  

Infection Cancer

Oxiconazole (Ro 13-8996) nitrate is a broad spectrum anti-fungal agent which can inhibit the growth of Candida, Aspergillus and Trichophyton. Oxiconazole nitrate is also a highly efficacious activator of CYP3A4 transactivation, which could be antagonized by Rifampicin (HY-B0272) in a competitive manner. Oxiconazole nitrate exhibits inhibitory effect against colorectal cancer (CRC) via peroxiredoxin-2 (PRDX2)-mediated autophagy arrest .
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2
2 Cited Publications
Cat. No.: HY-W050154
CAS No.: 501-30-4
Kojic acid is a substance produced by Aspergillus oryzae that is orally effective and can also be absorbed transdermally. Kojic acid exhibits various biological activities, including anti-aging, anti-nematode, antimicrobial, antioxidant, and anti-inflammatory effects. Kojic acid is a Tyrosinase inhibitor with an Mushroom Tyrosinase IC50 of 182.7 μM. Kojic acid prevents melanin production by capturing copper ions that bind to the tyrosinase active site, thus inhibiting its activation. Kojic acid also suppresses the NF-κB and p21 signaling pathways in human keratinocytes. Kojic acid derivatives have anticancer activity .
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1
1 Cited Publications
Cat. No.: HY-B2228
CAS No.: 9001-92-7
Proteinase, Aspergillus oryzae is a serine protease that hydrolyzes peptide bonds in protein substrates, preferring alkaline conditions (optimal pH 10.5). It efficiently degrades casein, poly-L-glutamic acid, and poly-L-lysine, with activity irreversibly inhibited by diisopropylfluorophosphate (DFP) and potato inhibitor. This enzyme catalyzes proteolysis via serine residues in its active site, finding applications in food processing (e.g., soy sauce fermentation), detergents, and leather industries due to its high yield in solid-state fermentation and cost-effective production.
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1
1 Cited Publications
Cat. No.: HY-113542
CAS No.: 100513-53-9
Synonyms: (+)-Blasticidin A
Target:  

Antibiotic Fungal

Research Areas:  

Infection

Blasticidin A ((+)-Blasticidin A) is a tetraamide acid derivative antibiotic produced by Streptomyces griseochromogenes, as well as a selective inhibitor of aflatoxin production. Blasticidin A exhibits antimicrobial activity against yeast. Blasticidin A can be used in research related to aflatoxin contamination (infection by Aspergillus sp.) .
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1
1 Cited Publications
Cat. No.: HY-N6829
CAS No.: 1245-15-4
Synonyms: Quercetin-​3,​3',​4',​7-​tetramethylether
Retusin (Quercetin-3,3',4',7-tetramethylether) is a tyrosinase inhibitor, with IC50 values of 50.9 μM and 51.8 μM against mushroom and intracellular tyrosinase, respectively. Retusin also acts as a free radical scavenger, melanogenesis inhibitor, anti-apoptosis agent, neuroprotective agent, antiemetic, antifungal agent, and antiviral agent. Retusin scavenges ABTS• + and DPPH• free radicals. Retusin can be used in studies related to hyperpigmentation, vomiting, Aspergillus niger infection, and COVID-19 infection .
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1
1 Cited Publications
Cat. No.: HY-N6783
CAS No.: 11052-72-5
Oligomycin C is a macrolide antibiotic produced by Streptomyces strains. Oligomycin C exhibits a strong activity against Aspergillus niger, Alternaria alternata, Botrytis cinerea and Phytophthora capsici but no activity toward bacteria .
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1
1 Cited Publications
Cat. No.: HY-107126
CAS No.: 1207753-03-4
Purity:  99.83%
Synonyms: MK 3118; SCY-078
Target:  

Fungal

Research Areas:  

Infection

Ibrexafungerp (MK 3118) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp can be used for research of Candida and Aspergillus infections .
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1
1 Cited Publications
Cat. No.: HY-30220
CAS No.: 20312-36-1
Synonyms: L-(-)-3-Phenyllactic Acid
(S)-2-Hydroxy-3-phenylpropanoic acid is the L-configuration of 2-Hydroxy-3-phenylpropanoic acid, and its level is closely related to some diseases, such as phenylketonuria .
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1
1 Cited Publications
Cat. No.: HY-107126A
CAS No.: 1965291-08-0
Purity:  99.38%
Synonyms: MK 3118 citrate; SCY-078 citrate
Target:  

Fungal

Research Areas:  

Infection

Ibrexafungerp citrate (MK 3118 citrate) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp citrate is an investigational agent for the treatment of Candida and Aspergillus infections .
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1
1 Cited Publications
Cat. No.: HY-P2996
CAS No.: 9029-27-0
Target:  

Others

Research Areas:  

Others

NAD(P)H-Nitrate reductase is isolated from Aspergillus niger that catalyses the reduction of nitrate to nitrite via a two-electron transfer. In plants, the electron donor for Nitrate reductase is NADPH is NADH:Nitrate reductase and a bispecific NAD(P)H: Nitrate reductase .
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1
1 Cited Publications
Cat. No.: HY-B0751
CAS No.: 23110-15-8
Synonyms: Amebacilin; NSC9168
Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
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1
1 Cited Publications
Cat. No.: HY-N6777
CAS No.: 90-65-3
Penicillic acid is a polyketide mycotoxin produced by several species of Aspergillus and Penicillium. Penicillic acid exhibits cytotoxicity in rat alveolar macrophages (AM) in vitro. Penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8 .
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1
1 Cited Publications
Cat. No.: HY-B0856
CAS No.: 37248-47-8
Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1?μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC50 of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM .
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