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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
CME
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "CME" in MCE Product Catalog:
35
35 Publications Verification
Pitstop 2 is a clathrin inhibitor which inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. Pitstop 2 has the potential for anti-cancer research .
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2 Cited Publications
Cat. No.: HY-119764
CAS No.: 36531-78-9
Category:
Microorganisms Antibiotics Other Diseases Disease Research Antibacterial Disease Research Fields Other Antibiotics
Target:
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1 Cited Publications
ES9-17 is an analog of ES9 (endosidin9), which is an inhibitor of clathrin heavy chain (CHC). ES9-17 is an inhibitor of clathrin-mediated endocytosis (CME), a major route for internalization of plasma membrane proteins and molecules from the extracellular environment in plants. ES9-17 inhibits the uptake of transferrin and FM4-64. ES9-17 also inhibits root growth of Arabidopsis seedings .
1
1 Cited Publications
Target:
Research Areas:
Dynole 2−24 is an indole-based dynamin GTPase inhibitor (IC50=0.56 μM for dynamin I). Dynole 2−24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC₅₀(CME)=1.9 μM). Dynole 2−24 also shows 4.4-fold selectivity for dynamin I. Dynole 2−24 is active in-cell inhibitor of clathrin-mediated endocytosis . CME: Clathrin mediated endocytosis
Cat. No.: HY-W013741
CAS No.: 2491-17-0
Cat. No.: HY-152216
CAS No.: 1345853-49-7
Target:
Research Areas:
Dynamin IN-2 (compound 43), a Wiskostatin (HY-12534) analogue, is a potent dynamin inhibitor, with an IC50 of 1.0 μM for dynamin I GTPase. Dynamin IN-2 also blocks clathrin mediated endocytosis (CME), with an IC50 of 9.5 μM .
Cat. No.: HY-152217
CAS No.: 2650733-69-8
Target:
Research Areas:
Clathrin-IN-2 is potent inhibitor of clathrin mediated endocytosis (CME) with an IC50 value of 2.3 μM. Clathrin-IN-2 also has inhibitiory for dyn I GTPase with an IC50 value of 7.7 μM .
Cat. No.: HY-172531
CAS No.: 3064686-59-2
Research Areas:
Sulfonadyn-47 is a GTP-competitive dynamin I (dynI) inhibitor that targets the active site in the GTPase domain of dynamin I, with IC50 values of 3.5 μM against dynI, 27.3 μM in clathrin-mediated endocytosis (CME) assays, and 12.3 μM in synaptic vesicle endocytosis (SVE) assays. Sulfonadyn-47 increases seizure threshold. Sulfonadyn-47 can be used the study for the seizure.
Cat. No.: HY-158097
Target:
Research Areas:
IAV-IN-2 (Compound MC-22) inhibits for Influenza A Virus (IAV) through blocking the entry of IAV into host cell via clathrin-mediated endocytosis (CME) .
Cat. No.: HY-122564
CAS No.: 1440126-94-2
Pyrimidyn 7 is an inhibitor of dynamin I/II with IC50 values of 1.1 μM and 1.8 μM, respectively. Pyrimidyn 7 competitively inhibits the interactions between GTP and phospholipids with dynamin I. Additionally, Pyrimidyn 7 reversibly inhibits clathrin-mediated endocytosis (CME) of transferrin and epidermal growth factor (EGF) in various non-neuronal cell linecell [1.
Cat. No.: HY-B1888AS
CAS No.: 2749400-35-7
Cat. No.: HY-N17736
CAS No.: 58546-61-5
Synonyms: CME
Cat. No.: HY-178643
CAS No.: 2747890-15-7
Research Areas:
DMTr-S-5-C-Me-2'-O-Me-rU-3'-CE-phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.
Cat. No.: HY-178663
CAS No.: 3055727-89-1
Research Areas:
DMTr-S-5-C-Me-2'-F-dA(Bz)-3'-CE-phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.
Cat. No.: HY-178568
CAS No.: 3060423-81-3
Research Areas:
DMTr-S-5-C-Me-2'-O-Me-rA(Bz)-3'-CE-phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.
Cat. No.: HY-178569
CAS No.: 1883486-16-5
Research Areas:
DMTr-S-5-C-Me-2'-O-Me-rC(Ac)-3'-CE-phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.
Cat. No.: HY-178660
CAS No.: 3055727-88-0
Research Areas:
DMTr-R-5'-C-Me-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
