50 Results for "

Coupling agent

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "Coupling agent" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-Y1168
CAS No.: 3945-69-5
Synonyms: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride
DMTMM (4-(4,6-dimethoxy-1,3,5-triazine-2-yl)-4-methylmorpholinium chloride) is a coupling agent. DMTMM can activate carboxyl groups and promote the formation of amide bonds. DMTMM plays an important role in promoting the chemical modification of biomacromolecules such as polysaccharides and proteins. DMTMM can be used for research of tissue engineering, breast cancer, corneal regeneration, and biomaterials .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-B0558
CAS No.: 22232-54-8
Target:  

p38 MAPK

Research Areas:  

Neurological Disease Endocrinology

Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P99205
CAS No.: 1020264-78-1

Target:  

ADC Antibodies

Research Areas:  

Cancer

Glembatumumab is a fully human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be coupled to the microtubule inhibitor monomethyl auristatin E to form glembatumumab vedotin. Glembatumumab vedotin is an antibody-agent coupling (ADC) with antitumor activity .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W013151
CAS No.: 114932-60-4
Research Areas:  

Others

1-Pyrenebutyric acid N-hydroxysuccinimide ester (PANHS) is a linker and interface coupling agent that can be used to prepare electrochemical biosensors. 1-Pyrenebutyric acid N-hydroxysuccinimide ester immobilizes SARS-CoV-2 spike antibodies on graphene sheets. 1-Pyrenebutyric acid N-hydroxysuccinimide ester is often used as an activation reagent for carboxylic acids in organic chemistry or biochemistry .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-15929
CAS No.: 14348-40-4
Synonyms: 2,4,6-Tribromo-3-hydroxybenzoic acid
TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) is a chemical colorimetric agent and nanomaterial surface modifier. TBHBA can react with some oxidants (such as H2O2) to generate high-absorbance quinoneimine dyes, which enhance the sensitivity of HDL cholesterol enzymatic determination. TBHBA can be used as a bromine-containing coupling agent to modify the surface of silica nanoparticles through esterification reaction. Thereby, organic flame retardant groups are introduced to improve the thermal stability and flame retardant properties of nanocomposites. TBHBA can be used in clinical biochemical testing (such as serum lipoprotein analysis) and the preparation of flame-retardant polymer nanocomposites .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W036410
CAS No.: 13822-56-5
Synonyms: 3-Aminopropyltrimethoxysilane
Aminopropyltrimethoxysilane (APTMS) is a silane coupling agent. Aminopropyltrimethoxysilane couples with Tosylcellulose. Aminopropyltrimethoxysilane improves the thermal stability of the material. Aminopropyltrimethoxysilane can be used in the preparation of GNBP substrates .
loading...
    loading...
Cat. No.: HY-79880
CAS No.: 530-62-1
Synonyms: 1,1'-Carbonyldiimidazole
Target:  

MOFs

Research Areas:  

Others

N,N'-Carbonyldiimidazole (1,1'-Carbonyldiimidazole) is a highly reactive carboxylating reagent that can activate hydroxyl groups to form reactive carbonyl groups. N,N'-Carbonyldiimidazole can be used as a coupling agent and a peptide synthesis reagent .
loading...
    loading...
Cat. No.: HY-140698
CAS No.: 92451-01-9
Purity:  ≥95.0%
Synonyms: mPEG5000-SC; mPEG5000-Succinimidyl ester
m-PEG5000-NHS ester (mPEG5000-SC) is a pegylation reagent that targets the primary amino groups of branched polyethyleneimine on gold nanoparticles. m-PEG1000-NHS ester covalently links its PEG moiety to target amino groups via amine-mediated coupling chemistry. m-PEG1000-NHS ester helps improve the biocompatibility of modified gold nanoparticles used as CT contrast agents and prolongs their blood circulation time.
loading...
    loading...
Cat. No.: HY-W127711
CAS No.: 14263-94-6
Fast Blue B Salt, Dye content ~95% is a diazo dye, primarily used as a chromogenic substrate in biochemical analysis. Fast Blue B Salt, Dye content ~95% is the coupling agent for the histochemical demonstration of proteases. Fast Blue B Salt, Dye content ~95% can be used for the detection of acid phosphatase in Clostridium perfringens, and also for the determination of lipase activity. Fast Blue B Salt, Dye content ~95% reacts directly with the active hydroxyl groups in phenolic compounds to determine the content of phenolic substances .
loading...
    loading...
Cat. No.: HY-P5623A
CAS No.: 1186105-01-0
Synonyms: RVG29-Cys; RDP-Cys; Rabies Virus Glycoprotein-29-Cys
Target:  

RABV

Research Areas:  

Others

RVG-Cys (RVG29-Cys) is a peptide derived from rabies virus glycoprotein (RVG29) with Cys attached to facilitate subsequent conjugation. RVG-Cys enhances the specific targeted delivery of proteins in brain tissue and neurons .
loading...
    loading...
Cat. No.: HY-W105426
CAS No.: 2530-85-0
Synonyms: [3-(Methacryloyloxy)propyl]trimethoxysilane
3-(Trimethoxysilyl)propyl methacrylate ([3-(Methacryloyloxy)propyl]trimethoxysilane) is a reactive monomer and silane coupling agent with C=C and O-C=O functional groups, acting as a surface modifier and anti-agglomeration agent. 3-(Trimethoxysilyl)propyl methacrylate can be used to prepare nanoparticles .
loading...
    loading...
Cat. No.: HY-133513
CAS No.: 1919794-40-3
Purity:  98.15%
Synonyms: (±)-H3L28
Target:  

Drug Derivative

Research Areas:  

Cancer

(±)-H3RESCA-TFP ((±)-H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA). (±)-H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine) .
loading...
    loading...
Cat. No.: HY-147363
CAS No.: 2758875-01-1
Purity:  99.69%
Research Areas:  

Others

DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a Camptothecin (HY-16560) derivative, is a linker-payload of protein-agent conjugates . Dxd (HY-13631D) can be used as a payload for the antibody-coupling drug ADC (DS-8201a).DIBAC-GGFG-NH2CH2-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
loading...
    loading...
Cat. No.: HY-147168
CAS No.: 102743-85-1
Purity:  99.24%
Research Areas:  

Others

Biocytin hydrazide is a long-chain biotin-containing hydrazide, serving as a biotin-derived active coupling reagent, selective labeling agent and biotinylating reagent. Biocytin hydrazide targets aldehyde, carboxyl, amino and guanidino groups to biotinylate glycoconjugates, K99 lectin, peptides and proteins through its hydrazide moiety, and achieves nonradioactive detection of sialic acid- and galactose-containing glycoconjugates via the avidin–biotin system .
loading...
    loading...
Cat. No.: HY-101532
CAS No.: 98169-85-8
Purity:  ≥98.0%
Synonyms: β-CDN3; 6A-deoxy-6A-azido-β-cyclodextrin
Research Areas:  

Others

6A-Azido-6A-deoxy-β-cyclodextrin (β-CDN3) is a site-specifically modified β-cyclodextrin with a single azido group replacing the hydroxyl group at the C6 position. 6A-Azido-6A-deoxy-β-cyclodextrin forms a host-guest inclusion complex with Dexamethasone (HY-14648), localizing the drug within its hydrophobic cavity, which restricts the rotational mobility of the drug and places Dexamethasone in a less polar environment. 6A-Azido-6A-deoxy-β-cyclodextrin acts as a coupling agent to graft β-cyclodextrin onto thermosensitive nanogels via strain-promoted alkyne-azide cycloaddition (SPAAC). 6A-Azido-6A-deoxy-β-cyclodextrin also serves as a click chemistry reagent. It contains an azide group and undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules bearing an alkyne group. It also undergoes strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
loading...
    loading...
Cat. No.: HY-158067
CAS No.: 2359695-48-8
Purity:  89.40%
Synonyms: DFO-DBCO
Deferoxamine-DBCO is a bifunctional chelating agent. Deferoxamine-DBCO efficiently chelates with radioactive metals (such as 89Zr) through the DFO structure to achieve radiolabeling. Deferoxamine-DBCO undergoes a metal-free Huisgen cycloaddition reaction with azide-containing biomolecules (such as siRNA, monoclonal antibodies) under bioorthogonal conditions through the DBCO structure to achieve targeted coupling. Deferoxamine-DBCO has efficient metal chelating ability and specific bioorthogonal reaction activity. Deferoxamine-DBCO can be used for targeted radioactive imaging studies of tumors .
loading...
    loading...
Cat. No.: HY-140699
CAS No.: 92451-01-9
Purity:  ≥98.0%
Synonyms: mPEG10000-SC; mPEG10000-Succinimidyl ester
m-PEG10000-NHS ester (mPEG10000-SC) is a pegylation reagent that targets the primary amino groups of branched polyethyleneimine on gold nanoparticles. m-PEG1000-NHS ester covalently links its PEG moiety to target amino groups via amine-mediated coupling chemistry. m-PEG1000-NHS ester helps improve the biocompatibility of modified gold nanoparticles used as CT contrast agents and prolongs their blood circulation time.
loading...
    loading...
Cat. No.: HY-46225
CAS No.: 2754462-35-4
Target:  

Drug Intermediate

Research Areas:  

Inflammation/Immunology

DEX-maleimide is a coupling agent that can be used to synthesize conjugates containing single-domain antibodies (VHH) conjugated with antigens and anti-inflammatory agents. DEX-maleimide can be used for research on autoimmune diseases .
loading...
    loading...
Cat. No.: HY-91018
CAS No.: 35141-36-7
Synonyms: N-[3-(Trimethoxysilyl)propyl]-N,N,N-trimethylammonium chloride, 50% in methanol
Trimethyl[3-(trimethoxysilyl)propyl]ammonium (N-[3-(Trimethoxysilyl)propyl]-N,N,N-trimethylammonium) chloride (50% in methanol) is a functional organic silane coupling agent and quaternary ammonium salt cationic functional monomer, which can be used for functionalizing mesoporous silica with electrochemical modified electrodes or surface chemical modification .
loading...
    loading...
Cat. No.: HY-Y0198
CAS No.: 141-86-6
2,6-Diaminopyridine is an intermediate and coupling agent for hair dyes. 2,6-Diaminopyridine participates in organic synthesis reactions such as N-methylation and can bind metal ions by forming macrocyclic ligands through condensation with aldehydes. 2,6-Diaminopyridine can be used to synthesize the analgesic phenazopyridine hydrochloride (HY-B0985) .
loading...
    loading...