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CuAAC

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1871

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111

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83

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17

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21

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56

Isotope-Labeled Compounds

1421

Click Chemistry

129

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1

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15680
    O-Propargyl-Puromycin
    25+ Cited Publications

    		 Biochemical Assay Reagents Others
    O-Propargyl-Puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-Propargyl-Puromycin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    O-Propargyl-Puromycin
  • HY-12008
    Erlotinib Hydrochloride
    Maximum Cited Publications
    134 Publications Verification

    CP-358774 hydrochloride; NSC 718781 hydrochloride; OSI-774 hydrochloride

    		 EGFR Autophagy Cancer
    Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Erlotinib Hydrochloride
  • HY-15458
    SAR131675
    5+ Cited Publications

    		 VEGFR Cancer
    SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM. SAR131675 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    SAR131675
  • HY-W040124
    DL-Propargylglycine
    2 Publications Verification

    		 Amino Acid Derivatives Others
    DL-Propargylglycine is a Glycine (HY-Y0966) derivative . DL-Propargylglycine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    DL-Propargylglycine
  • HY-138749
    Biotin alkyne
    1 Publications Verification

    		 PROTAC Linkers Cancer
    Biotin alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin alkyne
  • HY-W011210
    Fmoc-Pra-OH

    		Amino Acid Derivatives Others
    Fmoc-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Fmoc-Pra-OH
  • HY-15388
    Tazarotene
    2 Publications Verification

    AGN 190168

    		 RAR/RXR Autophagy Inflammation/Immunology Cancer
    Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis and acne vulgaris. Tazarotene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Tazarotene
  • HY-130109
    N3-PEG4-C2-NHS ester

    		ADC Linker Cancer
    N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    N3-PEG4-C2-NHS ester
  • HY-100949
    EC330
    5+ Cited Publications

    		 Interleukin Related Biochemical Assay Reagents Cancer
    EC330 is a leukemia inhibitory factor (LIF) inhibitor. EC330 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    EC330
  • HY-140335
    Alkynyl myristic acid
    4 Publications Verification

    		 PROTAC Linkers Cancer
    Alkynyl myristic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Alkynyl myristic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Alkynyl myristic acid
  • HY-B1710
    Norethindrone acetate

    19-Norethindrone acetate

    		 Progesterone Receptor Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Norethindrone acetate is a female hormone used for the research of endometriosis . Norethindrone acetate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norethindrone acetate
  • HY-102033
    Oxamflatin
    1 Publications Verification

    Metacept-3

    		 HDAC Cancer
    Oxamflatin (Metacept-3) is a potent HDAC inhibitor with an IC50 of 15.7 nM. Oxamflatin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Oxamflatin
  • HY-W800703
    Alexa Fluor 594 azide

    		Fluorescent Dye Others
    Alexa Fluor 594 azide is an azide-modified fluorescent dye and also a FRET acceptor reactant. Owing to its negligible direct absorption under 488 nm excitation light, excellent photostability, and the ability of its azide group to participate in the CuAAC reaction, Alexa Fluor 594 azide can be paired with a donor dye for single-molecule imaging via TIRFM, thereby enabling the visual monitoring of CuNP-catalyzed click reactions .
    Alexa Fluor 594 azide
  • HY-W615104
    BTTP

    		Biochemical Assay Reagents Others
    BTTP is a tris(triazolylmethyl)amine-based ligand. BTTP can accelerate the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC), the prototypical reaction in click chemistry .
    BTTP
  • HY-15964
    Tirasemtiv
    1 Publications Verification

    CK-2017357

    		 Biochemical Assay Reagents Neurological Disease
    Tirasemtiv is an activator of the fast skeletal muscle troponin complex. Tirasemtiv is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Tirasemtiv
  • HY-D1321
    Cy 5 amine hydrochloride
    1 Publications Verification

    Cyanine5 amine hydrochloride

    		 Fluorescent Dye Others
    Cyanine5 amine hydrochloride is a potent fluorescent dye. Cyanine5 amine hydrochloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm) .
    Cy 5 amine hydrochloride
  • HY-160893
    PSMA-azide

    		PSMA Cancer
    PSMA-azide is a prostate-specific membrane antigen (PSMA) ligand. PSMA-azide inhibits PSMA-dependent NAAG (N-acetylaspartylglutamic acid) hydrolysis, with an IC50 of 9 nM and a Ki of 1 nM. PSMA-azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups .
    PSMA-azide
  • HY-B1012
    Quinestrol

    W-3566

    		 Estrogen Receptor/ERR Endocrinology Cancer
    Quinestrol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Quinestrol
  • HY-D1320
    Cyanine5 azide chloride

    		Fluorescent Dye Others
    Cyanine5 azide chloride is a potent fluorescent dye. Cyanine5 azide chloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Cyanine5 azide chloride
  • HY-107362
    CH7057288

    		Trk Receptor Cancer
    CH7057288 is a potent and selective TRK inhibitor. CH7057288 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    CH7057288
  • HY-43614
    Propynol Ethoxylate

    		PROTAC Linkers Cancer
    Propynol Ethoxylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propynol Ethoxylate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Propynol Ethoxylate
  • HY-115495
    6-Alkynyl fucose

    		Biochemical Assay Reagents Others
    6-Alkynyl fucose is a tool in the study of protein O-fucosylation . 6-Alkynyl fucose is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    6-Alkynyl fucose
  • HY-W879007
    ICG-azide

    		Fluorescent Dye Others
    ICG-azide, a near infrared (NIR) fluorescent dye, is a copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reagent. ICG-azide can be readily incorporated into dye-stabilized nanoemulsions and facilitate the attachment of targeting ligands via click-chemistry in a simple, scalable, and reproducible reaction .
    ICG-azide
  • HY-101603
    Manitimus

    FK778

    		 Biochemical Assay Reagents Inflammation/Immunology
    Manitimus is an inhibitor of dehydroorotate dehydrogenase, and a potent immunosuppressive agent. Manitimus is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Manitimus
  • HY-10249D
    AKT Kinase Inhibitor hydrochloride
    15+ Cited Publications

    		 Akt Cancer
    AKT Kinase Inhibitor hydrochloride is an Akt kinase inhibitor with anti-tumor activity . AKT Kinase Inhibitor (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    AKT Kinase Inhibitor hydrochloride
  • HY-B0110
    Gestodene

    SHB 331; WL 70

    		 Progesterone Receptor Endocrinology
    Gestodene(SHB 331;WL 70) is a progestin-based contraceptive. Gestodene is a click chemistry reagent. It contains an alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an azide group .
    Gestodene
  • HY-114507
    Flumioxazin

    Sumisoya; V-53482

    		 Environmental Pollutants Herbicide Others
    Flumioxazin (Sumisoya) is an herbicide for use in soybean and peanut. Flumioxazin inhibits the enzyme protoporphyrinogen oxidase . Flumioxazin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Flumioxazin
  • HY-155639
    Tyramide alkyne
    1 Publications Verification

    		 Biochemical Assay Reagents Others
    Tyramide alkyne is an alternative labeling substrate that can be coupled to detection or enrichment moieties via a Copper-catalyzed Azide/Alkyne Cycloaddition (CuAAC) “click” reaction. Tyramide alkyne can be used for ascorbate peroxidase 2 (APEX2) labeling .
    Tyramide alkyne
  • HY-151859
    N3-Gly-Gly-OH

    		Biochemical Assay Reagents Others
    N3-Gly-Gly-Gly-OH is a click chemistry reagent containing an azide group. N3-Gly-Gly-OH undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkyne group. N3-Gly-Gly-OH also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. N3-Gly-Gly-Gly-OH can be used to construct peptide-like ADC linkers via click chemistry .
    N3-Gly-Gly-OH
  • HY-50713
    Calcium-Sensing receptor antagonist I

    		CaSR Others
    Calcium-Sensing receptor antagonist I is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Calcium-Sensing receptor antagonist I
  • HY-119532
    Nordeprenyl

    Desmethylselegiline

    		 Drug Metabolite Metabolic Disease
    Nordeprenyl is the metabolite of Deprenyl. Deprenyl is a potent, selective and irreversible inhibitor of MAO-B . Nordeprenyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Nordeprenyl
  • HY-79584
    Propargyl-Tos

    		ADC Linker Cancer
    Propargyl-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-Tos is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Propargyl-Tos
  • HY-W007319
    Phenylpropiolic acid

    		Endogenous Metabolite Metabolic Disease
    Phenylpropiolic acid is an endogenous metabolite. Phenylpropiolic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Phenylpropiolic acid
  • HY-W018008
    Ethynylferrocene

    Ferrocenylacetylene; Ferrocenylethyne

    		 Biochemical Assay Reagents Others
    Ethynylferrocene (Ferrocenylacetylene) is a click chemistry agent. Ethynylferrocene can be used for labeling of hairpin DNA probes to monitor the DNA hybridization via the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) .
    Ethynylferrocene
  • HY-151823
    8-Azido-octanoyl-OSu

    		ADC Linker Others
    8-Azido-octanoyl-OSu is a click chemistry reagent containing an azide group. Used as a building block to introduce 8-azidooctanoic acid (CAS 217180-76-2) fragment. This fragment is used for further modifications using Click-chemistry (CuAAC), as a protected aminogroup or is used in physico-chemical investigations . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    8-Azido-octanoyl-OSu
  • HY-136554
    WYC-210

    		Drug Derivative Cancer
    WYC-210, a Tazarotene derivative, is a retinoid compound with lower anticancer activity . WYC-210 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    WYC-210
  • HY-151212
    BCP-T.A

    		Ferroptosis Glutathione Peroxidase Cancer
    BCP-T.A, a tunable heterocyclic electrophile, is a potent ferroptosis inducer by binding to GPX4 . BCP-T.A is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    BCP-T.A
  • HY-16986B
    EPZ011989 hydrochloride
    3 Publications Verification

    		 Histone Methyltransferase Cancer
    EPZ011989 hydrochloride is a potent and orally active Zeste Homolog 2 (EZH2) inhibitor, with a Ki value of <3 nM. EPZ011989 shows anti-tumor activity. EPZ011989 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
    EPZ011989 hydrochloride
  • HY-136380
    Clodinafop-propargyl

    		Herbicide Others
    Clodinafop-propargyl, a main member of aryloxyphenoxy-propionate herbicides, is used for postemergence control of annual grasses in cereals, including Avena, Lolium, Setaria, Phalaris and Alopecurus spp . Clodinafop-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Clodinafop-propargyl has developmental toxicity to zebrafish embryos .
    Clodinafop-propargyl
  • HY-176846
    HIPS probe-1

    		Biochemical Assay Reagents Others
    HIPS probe-1 (Compound 1) is a click chemistry reagent containing a alkyne group. HIPS probe-1 can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. HIPS probe-1 can be used as a chemical probe to specifically recognize and label aldehyde functional groups in DNA, especially abasic sites (AP sites) for DNA damage research .
    HIPS probe-1
  • HY-175424
    N3-CMC

    		Others Others
    N3-CMC is a click chemistry reagent. N3-CMC containing an azide group can undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. N3-CMC can also undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. N3-CMC reacts specifically with the pseudouridine (Ψ)-containing RNA, and biotin is subsequently conjugated to the N3-CMC-Ψ RNA via click chemistry, quantitatively analyzing the dynamic changes of Ψ .
    N3-CMC
  • HY-B1089
    Ethynodiol diacetate

    Ethynodiol acetate

    		 Progesterone Receptor Endocrinology
    Ethynodiol diacetate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Ethynodiol diacetate
  • HY-147420
    Xelaglifam

    IDG-16177

    		 Free Fatty Acid Receptor Metabolic Disease
    Xelaglifam is a potent GPR40 agonist. Antihyperglycaemic activity . Xelaglifam is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Xelaglifam
  • HY-W051612A
    DL-Propargylglycine sodium
    2 Publications Verification

    		 Amino Acid Derivatives Biochemical Assay Reagents Others
    DL-Propargylglycine sodium is a Glycine (HY-Y0966) derivative. DL-Propargylglycine sodium is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
    DL-Propargylglycine sodium
  • HY-12008A
    Erlotinib mesylate

    CP-358774 mesylate; NSC 718781 mesylate; OSI-774 mesylate

    		 EGFR Autophagy Cancer
    Erlotinib mesylate (CP-358774 mesylate) inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib (mesylate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Erlotinib mesylate
  • HY-111430
    1-Ethynylnaphthalene

    		Cytochrome P450 Cancer
    1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 1B1. 1-Ethynylnaphthalene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    1-Ethynylnaphthalene
  • HY-W051612
    DL-Propargylglycine hydrochloride

    		Amino Acid Derivatives Others
    DL-Propargylglycine hydrochloride is a Glycine (HY-Y0966) derivative. DL-Propargylglycine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
    DL-Propargylglycine hydrochloride
  • HY-N3114
    Panaxydiol

    		Histamine Receptor Inflammation/Immunology
    Panaxydiol exhibits histamine-release inhibition activity . Panaxydiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Panaxydiol
  • HY-148793
    Resencatinib

    		c-Met/HGFR Cancer
    Resencatinib is a potent tyrosine kinase inhibitor with antineoplastic activity . Resencatinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Resencatinib
  • HY-105102
    Netivudine

    882C87

    		 Nucleoside Antimetabolite/Analog HSV Infection
    Netivudine is a nucleoside analogue with potent anti-varicella zoster virus activity. Netivudine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Netivudine

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