2903 Results for "

D3

" in MedChemExpress (MCE) Product Catalog:
Products (2903)

2903 Results for "D3" in MCE Product Catalog:

76
76 Publications Verification
Art. -Nr.: HY-10002
CAS. Nr.: 32222-06-3
Reinheit:  99.94%
Synonyms: 1,25-Dihydroxyvitamin D3
Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
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27
27 Cited Publications
Art. -Nr.: HY-15398
CAS. Nr.: 67-97-0
Reinheit:  99.94%
Synonyms: Cholecalciferol; Colecalciferol
Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
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20
20 Cited Publications
Art. -Nr.: HY-12705
CAS. Nr.: 25614-03-3
Synonyms: CB-154 free base
Target:  

Dopamine Receptor

Forschungsgebiete:  

Neurological Disease

Bromocriptine is a potent dopamine D2/D3 receptor agonist, which binds D2 dopamine receptor with pKi of 8.05±0.2.
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20
20 Cited Publications
Art. -Nr.: HY-12705A
CAS. Nr.: 22260-51-1
Reinheit:  99.90%
Synonyms: CB-154
Forschungsgebiete:  

Neurological Disease Cancer

Bromocriptine mesylate is a potent dopamine D2/D3 receptor agonist, which binds D2 dopamine receptor with pKi of 8.05. Bromocriptine mesylate is permeable to the blood-brain barrier [3] .
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14
14 Cited Publications
Art. -Nr.: HY-32351
CAS. Nr.: 19356-17-3
Synonyms: 25-Hydroxy Vitamin D3
Calcifediol (25-hydroxy Vitamin D3) is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels [3].
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14
14 Cited Publications
Art. -Nr.: HY-32351A
CAS. Nr.: 63283-36-3
Synonyms: 25-hydroxy Vitamin D3 monohydrate
Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels [3].
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14
14 Cited Publications
Art. -Nr.: HY-B0410
CAS. Nr.: 104632-26-0
Target:  

Dopamine Receptor

Forschungsgebiete:  

Neurological Disease

Pramipexole is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with Kis of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D2, D3 and D4 receptors, respectively. Pramipexole can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS) [3].
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14
14 Cited Publications
Art. -Nr.: HY-B0410A
CAS. Nr.: 191217-81-9
Target:  

Dopamine Receptor

Forschungsgebiete:  

Neurological Disease

Pramipexole dihydrochloride hydrate is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with Kis of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D2, D3 and D4 receptors, respectively. Pramipexole dihydrochloride hydrate can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS) [3].
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14
14 Cited Publications
Art. -Nr.: HY-17355
CAS. Nr.: 104632-25-9
Target:  

Dopamine Receptor

Forschungsgebiete:  

Neurological Disease

Pramipexole dihydrochloride is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with Kis of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D2, D3 and D4 receptors, respectively. Pramipexole dihydrochloride can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS) [3].
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13
13 Cited Publications
Art. -Nr.: HY-15296
CAS. Nr.: 81409-90-7
Reinheit:  99.86%
Synonyms: FCE-21336
Forschungsgebiete:  

Endocrinology Cancer

Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).
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12
12 Cited Publications
Art. -Nr.: HY-B1019
CAS. Nr.: 15676-16-1
Target:  

Dopamine Receptor

Forschungsgebiete:  

Neurological Disease

Sulpiride is an orally active dopamine D2/D3 receptor antagonist. Sulpiride is an atypical antipsychotic agent of the benzamide family. Sulpiride can be used in research into anxiety, depression and breast cancer [3].
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11
11 Cited Publications
Art. -Nr.: HY-103414
CAS. Nr.: 84225-95-6
Reinheit:  99.83%
Target:  

Dopamine Receptor

Forschungsgebiete:  

Neurological Disease

Raclopride is a dopamine D2/D3 receptor antagonist with potential antipsychotic effects. Raclopride binds to D2 and D3 receptors with Kis of 1.8 nM and 3.5 nM, respectively .
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11
11 Cited Publications
Art. -Nr.: HY-14546
CAS. Nr.: 129722-12-9
Reinheit:  99.95%
Synonyms: OPC-14597
Aripiprazole (OPC-14597), an atypical antipsychotic, is a potent and high-affinity dopamine D2 receptor partial agonist. Aripiprazole is an inverse agonist at 5-HT2B and 5-HT2A receptors and displays partial agonist actions at 5-HT1A, 5-HT2C, D3, and D4 receptors. Aripiprazole can be used for the research of schizophrenia and COVID19 [3] .
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11
11 Cited Publications
Art. -Nr.: HY-14546A
CAS. Nr.: 851220-85-4
Synonyms: OPC-14597 monohydrate
Aripiprazole (OPC-14597) monohydrate, an atypical antipsychotic, is a potent and high-affinity dopamine D2 receptor partial agonist. Aripiprazole monohydrate is an inverse agonist at 5-HT2B and 5-HT2A receptors and displays partial agonist actions at 5-HT1A, 5-HT2C, D3, and D4 receptors. Aripiprazole monohydrate can be used for the research of schizophrenia and COVID19 [3] .
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8
8 Cited Publications
Art. -Nr.: HY-113279
CAS. Nr.: 434-16-2
Reinheit:  99.97%
7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.
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8
8 Cited Publications
Art. -Nr.: HY-12987
CAS. Nr.: 2062-78-4
Reinheit:  99.91%
Synonyms: R6238
Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; Pimozide also inhibits STAT3 and STAT5.
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7
7 Cited Publications
Art. -Nr.: HY-14763
CAS. Nr.: 839712-12-8
Reinheit:  99.83%
Synonyms: RGH-188
Forschungsgebiete:  

Neurological Disease

Cariprazine is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
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7
7 Cited Publications
Art. -Nr.: HY-14763A
CAS. Nr.: 1083076-69-0
Reinheit:  99.90%
Synonyms: RGH188 hydrochloride
Forschungsgebiete:  

Neurological Disease

Cariprazine hydrochloride is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
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6
6 Cited Publications
Art. -Nr.: HY-32343
CAS. Nr.: 55721-11-4
Synonyms: (24R)-24,25-Dihydroxyvitamin D3
Secalciferol ((24R)-24,25-Dihydroxyvitamin D3) is the major active metabolite of Vitamin D. Secalciferol activates vitamin D receptor (VDR) with an EC50 value of 150 nM. Secalciferol is involved in a wide range of biological functions such as calcium homeostasis, cellular differentiation and proliferation processes, as well as other functions related to the immune system, which is promising for research of rickets, osteomalacia, hypercalcemia and autoimmune disorders [3] .
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6
6 Cited Publications
Art. -Nr.: HY-B0413S
CAS. Nr.: 1228182-47-5
Fenbendazole-d3 is a deuterium labeled Fenbendazole. Fenbendazole-d3 is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 [3] .
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