Search Result
Results for "
Dextran
" in MedChemExpress (MCE) Product Catalog:
104
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-128868A
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Fluorescent Dye
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Others
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FITC-Dextran (MW 4000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
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- HY-128868
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Fluorescent Dye
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Others
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FITC-Dextran (MW 10000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 10000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 10000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
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- HY-128868D
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Fluorescent Dye
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Others
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FITC-Dextran (MW 40000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 40000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 40000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
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- HY-116282
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DSS (MW 5000); DXS (MW 5000)
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HIV
Complement System
Apoptosis
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Infection
Inflammation/Immunology
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Dextran sulfate sodium salt (DSS) (MW 5000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt (DSS) with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 5000) is an inhibitor of complement and coagulation pathways, and belongs to the glycosaminoglycans (GAG) family. Dextran sulfate sodium salt (MW 5000) acts as an anticoagulant, antiviral, and anti-lipemic agent. Dextran sulfate sodium salt (DSS) stops HIV-1 virus adsorption to host cells. Dextran sulfate sodium salt (MW 5000) prevents NK cell-mediated cytotoxicity. Dextran sulfate sodium salt (MW 5000) inhibits instant blood-mediated inflammatory reaction (IBMIR) .
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- HY-116282C
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DSS (MW 35000-45000); DXS (MW 35000-45000)
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Apoptosis
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Infection
Inflammation/Immunology
Cancer
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Dextran sulfate sodium salt (DSS) (MW 35000-45000) is a polymer of dehydrated glucose with a molecular weight of approximately 35000-45000. DSS with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (DSS) (MW 35000-45000) is a potent inducer of colitis. Dextran sulfate sodium salt (DSS) (MW 35000-45000) can be used to induce model acute colitis, chronic colitis, and colitis-related colon cancer. Dextran sulfate sodium salt (DSS) (MW 35000-45000) may be related to macrophage dysfunction, intestinal flora dysbiosis, and is particularly toxic to the colonic epithelium .
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- HY-112624P
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Dextran 500; Dextran D500; Dextran T500(MW 440000-560000)
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Biochemical Assay Reagents
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Others
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Dextran T500 MW 500,000 (Dextran 500; Dextran D500; Dextran T500 MW 440000-560000) is a polymer of anhydroglucose with the average molecular weight of 500,000. Dextran T500 MW 500,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
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- HY-112624
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Dextran
2 Publications Verification
Dextran 40
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Bacterial
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Cardiovascular Disease
Cancer
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Dextran (Dextran 40) has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander.
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- HY-112624B
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Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)
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Bacterial
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Others
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Dextran 70,000 is a high molecular weight polysaccharide formed by glucose linked by α-(1→6) glycosidic bonds. Dextran 70,000 can expand blood volume through colloidal osmotic pressure effect and inhibit cell adhesion and platelet aggregation through steric hindrance. At the same time, Dextran 70,000 can be used as a drug carrier to achieve targeted delivery through endocytosis. Dextran 70,000 is biologically inert and has low immunogenicity. It can be used for clinical blood volume expansion, anti-thrombotic research, and evaluation of vascular permeability in in vitro experiments. It can also be combined with fluorescent dyes for cell tracking and drug delivery research. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance.
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- HY-107928
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- HY-112624L
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Dextran 10; Dextran D10; Dextran T10(MW 8000-12000)
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Biochemical Assay Reagents
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Cancer
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Dextran T10 (MW 10,000) (Dextran 10) is a dehydrated glucose polymer with an average molecular weight of 10,000. Dextran T10 (MW 10,000) is composed of repeated glucose units, and it has abundant hydroxyl (-OH) groups, which can be used as a natural "magnetic marker" for chemical exchange saturation transfer (CEST) MRI imaging .
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- HY-128868G
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Fluorescent Dye
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Others
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FITC-Dextran (MW 150000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=491 nm; Em=518 nm). FITC-Dextran (MW 150000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 150000) can be used in perfusion studies in animals or in fluorescence microlymphography, to study processes that affect the permeability of the blood brain barrier (BBB) . FITC-Dextran (MW 150000) can be used as fluorescent probe to study cell permeability .
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- HY-116282A
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DSS (MW 4500-5500); DXS (MW 4500-5500)
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HIV
Apoptosis
Complement System
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Infection
Inflammation/Immunology
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Dextran sulfate sodium salt (DSS) (MW 4500-5500) is a polymer of dehydrated glucose with a molecular weight of approximately 4500-5500. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 4500-5500) is an inhibitor of complement and coagulation pathways, and belongs to the glycosaminoglycans (GAG) family. Dextran sulfate sodium salt (MW 4500-5500) acts as an anticoagulant, antiviral, and anti-lipemic agent. Dextran sulfate sodium salt (MW 4500-5500) stops HIV-1 virus adsorption to host cells. Dextran sulfate sodium salt (MW 4500-5500) prevents NK cell-mediated cytotoxicity. Dextran sulfate sodium salt (MW 4500-5500) inhibits instant blood-mediated inflammatory reaction (IBMIR) .
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- HY-128868H
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Biochemical Assay Reagents
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Others
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FITC-Dextran (MW 500000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments.
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- HY-116282D
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DSS (MW 450000-550000); DXS (MW 450000-550000)
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HIV
Influenza Virus
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Others
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Dextran sulfate sodium salt (DSS) (MW 450000-550000) is a polymer of dehydrated glucose with a molecular weight of approximately 450000-550000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 450000-550000) inhibits replication of HIV-1 and influenza A virus. Dextran sulfate sodium salt (MW 450000-550000) can be formulated as nanoparticles and shows antibacterial activity. Dextran sulfate sodium salt (MW 450000-550000) can be used for functional material preparation .
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- HY-158082C
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Tetramethyl rhodamine isothiocyanate glucan, MW 70000
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Fluorescent Dye
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Others
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TRITC-dextran MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye with a molecular weight of 70 kD. The excitation wavelength of TRITC-dextran MW 70000 is 555 nm, and its emission wavelength is 570 nm. TRITC-dextran MW 70000 is used for drug delivery because TRITC maintains stability over a wide pH range (i.e., pH 2-11) and exhibits photobleaching resistance .
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- HY-112624A
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Dextran 1; Dextran D1; Dextran T1(MW 800-1200)
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Biochemical Assay Reagents
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Others
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Dextran T1 (Dextran 1; Dextran D1) (with a molecular weight of 1,000) is a dehydrated glucose polymer with an average molecular weight of 1,000. Dextran T1 (MW 1,000) has excellent biodegradability and biocompatibility, and can be used as a nanobody carrier scaffold and a freeze-drying protectant. Dextran T1 (MW 1,000) promotes the retention of circulating tumor cells in the capillary bed .
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- HY-112624C
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Biochemical Assay Reagents
Endogenous Metabolite
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Others
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Dextran (MW 40000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds. Dextran has excellent solubility in water, making it useful as a viscosity modifier or stabilizer in foods, paints and adhesives. In the biomedical field, dextran is often used as a plasma expander because of its ability to increase blood volume when administered intravenously. It can also be modified to create dextran-based drug delivery systems, such as targeted nanoparticles.
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- HY-W134327A
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Diethylaminoethyl Dextran (MW 500000)
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Biochemical Assay Reagents
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Others
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DEAE-Dextran (MW 500000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds and modified with diethylaminoethyl (DEAE) groups. DEAE-Dextran is a cationic molecule that can be used as a transfection reagent to deliver nucleic acids such as DNA or RNA into cells. Its positive charge interacts with negatively charged cell membranes, facilitating the uptake of nucleic acids. DEAE-Dextran can also be used as an ion-exchange chromatography resin, allowing the separation and purification of biomolecules based on their charge.
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- HY-112624I
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Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)
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Bacterial
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Others
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Dextran T3 (Dextran 3; Dextran T3(MW 2400-3600)) is a neural tracer and intestinal permeability probe that can move anterogradely and retrogradely in neuronal axons by passive diffusion. Dextran T3 (MW 3,000) is able to permeate across the intestinal epithelial cell membrane in the presence of cholera toxin-induced cytoskeletal disturbance. Dextran T3 (MW 3,000) is used as a fluorescent marker to rapidly label developing neurons (such as Xenopus retinal ganglion cells) and to assess intestinal barrier function. It can be used to study axonal transport in neuroanatomy and permeability changes in intestinal pathophysiology. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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- HY-112624J
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Dextran 4; Dextran D4; Dextran T4(MW 3200-4800)
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Bacterial
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Others
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Dextran 4,000 is a mucus rheology modifier. The dextran molecules in Dextran 4,000 can reduce the cross-link density of mucus through osmotic effects and hydrogen bond substitution, and reduce viscoelasticity and improve the mucociliary/cough clearance index by destroying the DNA-mucin network structure in mucus. Dextran 4,000 has the ability to improve the rheological properties and clearance ability of cystic fibrosis (CF) sputum, and can be used in the study of inhalation therapy or aerosol delivery of mucostatic respiratory diseases. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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- HY-116282B
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DSS (MW 16000-24000); DXS (MW 16000-24000)
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Biochemical Assay Reagents
STING
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Others
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Dextran sulfate sodium salt (DSS) (MW 16000-24000) is a polymer of dehydrated glucose with a molecular weight of approximately 16000-24000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 16000-24000) induces STING polymerization and TBK1 activation .
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- HY-112624D
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Dextran 60; Dextran D60; Dextran T60(MW 54000-66000)
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Biochemical Assay Reagents
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Others
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Dextran T60 MW 60,000 (Dextran 60; Dextran D60; Dextran T60 MW 54000-66000) is a polymer of anhydroglucose with the average molecular weight of 60,000. Dextran T60 MW 60,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
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- HY-116282I
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DSS (MW>500000); DXS (MW>500000)
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HSV
SARS-CoV
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Inflammation/Immunology
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Dextran sulfate sodium salt (MW>500000) (DSS (MW>500000)) is a negatively charged sulfated polysaccharide. Dextran sulfate sodium salt has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate sodium salt can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .
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- HY-112624F1
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Fluorescent Dye
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Others
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CY5-Dextran (MW 4000) is a fluorescent dye CY5 (HY-D0821)-labeled Dextran (HY-112624). Dextran-CY5 (MW 4000) can be used to visualize the specific subcellular distribution of dextran at the nanoscale .
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- HY-112624Q
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Dextran 800; Dextran D800; Dextran T800(MW 750000-850000)
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Biochemical Assay Reagents
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Others
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Dextran T800 MW 800,000 (Dextran 800; Dextran D800; Dextran T800 MW 750000-850000) is a polymer of anhydroglucose with the average molecular weight of 800,000. Dextran T800 MW 800,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
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- HY-112624T
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Dextran 7; Dextran D7; Dextran T7(MW 5600-8400)
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Biochemical Assay Reagents
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Others
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Dextran T7 (Dextran 7; Dextran D7) (MW 7,000) is a polymer of anhydroglucose with the average molecular weight of 7000. Dextran T7 (MW 7,000) exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
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- HY-112624N
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Dextran 200; Dextran D200; Dextran T200(MW 180000-220000)
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Biochemical Assay Reagents
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Others
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Dextran T200 (Dextran 200; Dextran D200) (MW 200,000) is a dehydrated glucose polymer with an average molecular weight of 200,000. Dextran T200 (MW 200,000) has excellent biodegradability and good biocompatibility, and can be used as a high-molecular-weight tracer and optical clearing agent .
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- HY-112624M
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Dextran 150; Dextran D150; Dextran T150(MW 130000-170000)
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Biochemical Assay Reagents
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Others
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Dextran T150 (Dextran 150; Dextran D150) (MW 150,000) is a dehydrated glucose polymer with an average molecular weight of 150,000. Dextran T150 (MW 150,000) has excellent biodegradability and good biocompatibility, and can be used as a fluorescent labeling tracer and a high-molecular cross-linking agent .
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- HY-112624U
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Dextran 20; Dextran D20; Dextran T20(MW 16000-24000)
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Biochemical Assay Reagents
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Others
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Dextran T20 (Dextran 20; Dextran D20) (MW 20,000) is a dehydrated glucose polymer with an average molecular weight of 20,000. Dextran T20 (MW 20,000) has excellent biodegradability and good biocompatibility, and can be used as a gene delivery vector, an immune adjuvant carrier, and a hemoglobin stabilizer .
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- HY-112624H
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Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)
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Biochemical Assay Reagents
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Others
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Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM2), and Isomaltotriose (IM3). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity .
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- HY-112624K
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Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)
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Apoptosis
Autophagy
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Others
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Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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- HY-112624O
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Dextran 100; Dextran D100; Dextran T100(MW 90000-110000)
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Biochemical Assay Reagents
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Others
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Dextran T100 (MW 100,000) (Dextran 100; Dextran D100) is a dehydrated glucose polymer with an average molecular weight of 100,000. Dextran T100 (MW 100,000) has an α-(1→6)-linked D-glucose backbone and α-(1→4)-, α-(1→3)- or α-(1→2)-linked D-glucose side chains, and it is synthesized by lactic acid bacteria or their enzymes. Dextran T100 (MW 100,000) possesses favorable biodegradability and biocompatibility, and it can be used in the fields of food, pharmaceuticals, cosmetics and research .
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- HY-112624E
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Dextran 0.8; Dextran D0.8; Dextran T0.8(MW 640-960)
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Biochemical Assay Reagents
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Others
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Dextran T0.8 (Dextran 0.8; Dextran T0.8(MW 640-960)) is a food additive with a porous network structure that exhibits strong hydration capacity and low browning activity. Dextran T0.8 (MW 800) can improve the coagulation of dairy products and is used as a prebiotic in baked goods. Dextran T0.8 (MW 800) is non-toxic to HeLa cells at a concentration of ~500 μg/mL and has a low relative browning rate in the Maillard reaction. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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- HY-W134328
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Dextran blue (MW 2000000)
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Biochemical Assay Reagents
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Others
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Blue dextran (Dextran blue) (MW 2000000) is a high-molecular-weight long-chain polymer of D-glucose. Blue dextran (MW 2000000) serves as an important model macromolecular drug and molecular weight estimation marker, and can be used as a standard for gel permeation chromatography. The release of Blue dextran (MW 2000000) from alginate microspheres is regulated by preparation conditions; its release rate in a pH 6.8 environment is significantly faster than that in pH 1.2, and it exhibits release characteristics close to zero-order kinetics under this condition .
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- HY-116282M
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Bacterial
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Inflammation/Immunology
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Dextran sulfate, low sulfate (MW 40000), a biopolymer, is a sulfated polysaccharide. Dextran sulfate, low sulfate (MW 40000) has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .
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- HY-112624F
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Fluorescent Dye
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Others
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CY7-Dextran (MW 4000) is a fluorescent dye that consists of CY7 (HY-D0825) and Dextran (HY-112624) (Ex=740 nm; Em=770 nm). CY7-Dextran (MW 4000) can be used as a cell volume indicator and delineates the thin peripheral edges of the cells .
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- HY-P2840
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Endogenous Metabolite
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Metabolic Disease
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Dextranase, Trichoderma reesei, glucan hydrolase, is often used in biochemical research. Dextranase can catalyze the hydrolysis of α-(1,6)-glucosidic bonds in dextran, and has a wide range of applications, such as food processing, sugar modification, agent preparation, and medicine for enhancing the activity of endocarditis antibiotics wait .
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- HY-W134328E
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Dextran blue (MW 70000)
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Biochemical Assay Reagents
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Others
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Blue dextran (MW 70000) (Dextran blue (MW 70000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin .
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- HY-D2465
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Fluorescent Dye
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Others
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CY5-Dextran is a fluorescent dye CY5 (HY-D0821)- labeled Dextran (HY-112624). CY5 exhibits a maximal excitation wavelength of 633 nm, and a maximal emission wavelength of 670 nm. Dextran-CY5 can be used to visualize the specific subcellular distribution of dextran at the nanoscale .
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- HY-172163
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- HY-164071
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CM-Dextran
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Drug Derivative
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Others
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Carboxymethyl Dextran (CM-Dextran) is a dextran derivative and a biocompatible coating for superparamagnetic iron oxide nanoparticles. When coated on the surface of superparamagnetic nanoparticles, Carboxymethyl Dextran forms stable particles across all pH values and NaCl concentrations. Carboxymethyl Dextran can be used to prepare materials for magnetic resonance molecular imaging .
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- HY-W134328C
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Dextran blue (MW 20000)
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Biochemical Assay Reagents
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Others
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Blue dextran (MW 20000) (Dextran blue (MW 20000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin .
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- HY-159067
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DEAE-Dextran, MW 500000 hydrochloride, from bacterial (Leuconostoc mesenteroides); Diethylaminoethyl-Dextran, MW 500000 hydrochloride
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Biochemical Assay Reagents
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Cancer
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DEAE-dextran, MW 500000 hydrochloride (DEAE-dextran, MW 500000 hydrochloride, from bacterial (Leuconostoc mesenteroides)) is a high-molecular-weight positively charged polymer that significantly enhances the uptake of viral RNA by tissue culture cells. When employed in the delivery system for "tumor immunity" RNA-splenocyte transfer, DEAE-dextran can markedly extend the lifespan of tumor-bearing animals, comparable to that of actively immunized animals. Furthermore, DEAE-dextran serves as a complexing agent for nucleic acids, forming composite particles with DNA/RNA for extensive applications in gene delivery. Additionally, DEAE-dextran can be utilized as a coating for liposomes .
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- HY-172163A
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- HY-172163B
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- HY-172163C
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- HY-W134328A
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Dextran blue (MW 5000)
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Biochemical Assay Reagents
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Others
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Blue dextran (MW 5000) (Dextran blue (MW 5000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin .
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- HY-172164B
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Fluorescent Dye
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Others
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FITC-lysine-dextran, 70kDa is a dextran with lysine coupling with a fluorescent group FITC (HY-66019). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-116282P
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Bacterial
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Infection
Inflammation/Immunology
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Dextran sulfate, high sulfate (MW 5000) is a type of dextran sulfate with a high degree of sulfation. Dextran sulfate sodium can be used to induce ulcerative colitis models, and the greater the total number of sulfur atoms, the stronger the induced toxic effect. Dextran sulfate has certain antibacterial activity, and can form the ionic cross-linking core of nanoparticles together with chitosan, serving as a highly efficient dressing material to accelerate wound healing .
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- HY-116282J
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Bacterial
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Inflammation/Immunology
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Dextran sulfate, low sulfate (MW 5000), a biopolymer, is a sulfated polysaccharide. Dextran sulfate, low sulfate (MW 5000) has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .
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-
- HY-116282W
-
|
DSS (MW 6500-10000); DXS (MW 6500-10000)
|
HIV
|
Inflammation/Immunology
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|
Dextran sulfate sodium salt (DSS) (MW 6500-10000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 6500-10000) has antiviral activity against HIV-1 and HIV-2. Dextran sulfate sodium salt (MW 6500-10000) blocks the binding of virions to CD4 ⁺ T lymphocytes and inhibits syncytia formation. Dextran sulfate sodium salt (MW 6500-10000) also prevents experimental urolithiasis due to its cytoprotective actions. Moreover, because of its biocompatible and highly charged properties, Dextran sulfate sodium salt (MW 6500-10000) is a suitable choice for pharmaceutical systems .
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-
- HY-116282H
-
|
DSS (MW 9000-20000); DXS (MW 9000-20000)
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
|
Dextran sulfate sodium salt (DSS) (MW 9000-20000) is a polymer of dehydrated glucose with a molecular weight of approximately 9000-20000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 9000-20000) is a biocompatible and biodegradable biochemical reagent and can be used for pharmaceutical and biomedical applications .
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-
- HY-D2460
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
Cancer
|
|
Dextran-CY5.5 is a CY5.5 (HY-D0924) labeled Dextran (HY-112624) conjugate. CY5.5 is a Cyanine dye (The excitation wavelength is usually 673 nm and the emission wavelength is 707 nm) that can be used for the labeling of proteins, antibodies and small molecular compounds. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander .
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-
- HY-W134328B
-
|
Dextran blue (MW 10000)
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Biochemical Assay Reagents
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Others
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Blue dextran (Dextran blue) (MW 10000) is a 10 kDa osmotic dextran. Blue dextran (MW 10000) penetrates all sublayers of the pre-epithelial mucus gel layer in the rat distal colon and is taken up by the nuclei of surface cells in the rat distal colonic mucosa. Blue dextran (MW 10000) is not blocked by the pre-epithelial mucus gel layer of the rat distal colon, which acts as a diffusion barrier .
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-
- HY-P2723
-
-
- HY-164070
-
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Biochemical Assay Reagents
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Others
|
|
Dextran Hydroxypropyltrimonium Chloride is a cationic polymer with excellent antistatic, moisturizing, film-forming, foam-stabilizing and emulsifying abilities. Dextran Hydroxypropyltrimonium Chloride can be used in the research of pharmaceuticals and cosmetics .
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-
- HY-D2460A
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
Cancer
|
|
Dextran-CY5.5 (MW 10000) is a CY5.5 (HY-D0924) labeled Dextran (HY-112624) conjugate. CY5.5 is a Cyanine dye (The excitation wavelength is usually 673 nm and the emission wavelength is 707 nm) that can be used for the labeling of proteins, antibodies and small molecular compounds. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander .
|
-
- HY-D2460B
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
Cancer
|
|
Dextran-CY5.5 (MW 40000) is a CY5.5 (HY-D0924) labeled Dextran (HY-112624) conjugate. CY5.5 is a Cyanine dye (The excitation wavelength is usually 673 nm and the emission wavelength is 707 nm) that can be used for the labeling of proteins, antibodies and small molecular compounds. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander .
|
-
- HY-W134328D
-
|
Dextran blue (MW 40000)
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Biochemical Assay Reagents
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Others
|
|
Blue dextran (MW 40000) (Dextran blue (MW 4000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin .
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-
- HY-W134328I
-
|
Dextran blue (MW 500000)
|
Biochemical Assay Reagents
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Others
|
|
Blue dextran (MW 500000) (Dextran blue (MW 500000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin .
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-
- HY-W134328H
-
|
Dextran blue (MW 110000)
|
Biochemical Assay Reagents
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Others
|
|
Blue dextran (MW 110000) (Dextran blue (MW 110000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin .
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-
- HY-164072
-
|
|
Biochemical Assay Reagents
|
Others
Cancer
|
|
DBCO-Dextran is a dibenzocyclooctyne-modified dextran with excellent click chemistry activity and biocompatibility, which can be used in cancer immunotherapy and bioimaging research .
|
-
- HY-172164
-
|
|
Fluorescent Dye
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Others
|
|
FITC-lysine-dextran, 4kDa is a dextran with lysine coupling with a fluorescent group FITC (HY-66019). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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-
- HY-172166A
-
|
|
Fluorescent Dye
|
Others
|
|
TRITC-lysine-dextran, 10kDa is a dextran with lysine coupling with a fluorescent group TRITC (HY-D0791). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
|
-
- HY-164073
-
|
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Biochemical Assay Reagents
|
Others
|
|
Allylate Dextran is an allyl dextran with good biocompatibility and stability, which can be used for research on immune modulation and targeted delivery .
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-
- HY-172165A
-
|
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Biochemical Assay Reagents
|
Others
|
|
Lysine-dextran, 10kDa is a dextran with lysine coupling. Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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-
- HY-172165B
-
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Biochemical Assay Reagents
|
Others
|
|
Lysine-dextran, 20kDa is a dextran with lysine coupling. Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
|
-
- HY-172165
-
|
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Biochemical Assay Reagents
|
Others
|
|
Lysine-dextran, 4kDa is a dextran with lysine coupling. Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
|
-
- HY-D2429
-
|
|
Fluorescent Dye
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Others
|
|
Dextran-PEG-Cy3 is the Cy3 (HY-D0822)-labeled Dextran-PEG conjugate. Dextran-PEG is used as polymer-polymer systems for the high biocompatibility to maintain cell osmolarity. Dextran-PEG coatings can reduce nanoparticle cytotoxicity .
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-
- HY-172164A
-
|
|
Fluorescent Dye
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Others
|
|
FITC-lysine-dextran, 10kDa is a dextran with lysine coupling with a fluorescent group FITC (HY-66019). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
|
-
- HY-172164C
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-lysine-dextran, 500kDa is a dextran with lysine coupling with a fluorescent group FITC (HY-66019). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
|
-
- HY-172166
-
|
|
Fluorescent Dye
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Others
|
|
TRITC-lysine-dextran, 4kDa is a dextran with lysine coupling with a fluorescent group TRITC (HY-D0791). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
|
-
- HY-172166B
-
|
|
Fluorescent Dye
|
Others
|
|
TRITC-lysine-dextran, 70kDa is a dextran with lysine coupling with a fluorescent group TRITC (HY-D0791). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
|
-
- HY-150352
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-COOH is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and other functional materials .
|
-
- HY-158227
-
|
DexMA (MW 200000)
|
Biochemical Assay Reagents
|
Others
|
Dextran Methacryloyl (MW 200000) is a methacryloyl dextran that converts into cell matrix gels. Dextran Methacryloyl (MW 200000) formed gels that had no cytotoxic effects on fibroblasts, but cells adhered only inefficiently in long-term experiments . Dextran Methacryloyl (MW 200000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity. Application: cell culture, biological 3D printing, tissue engineering, etc.
|
-
- HY-172165C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Lysine-dextran, 40kDa is a dextran with lysine coupling. Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
|
-
- HY-172165D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Lysine-dextran, 70kDa is a dextran with lysine coupling. Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
|
-
- HY-172165E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Lysine-dextran, 150kDa is a dextran with lysine coupling. Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
|
-
- HY-172165H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Lysine-dextran, 500kDa is a dextran with lysine coupling. Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
|
-
- HY-172166C
-
|
|
Fluorescent Dye
|
Others
|
|
TRITC-lysine-dextran, 500kDa is a dextran with lysine coupling with a fluorescent group TRITC (HY-D0791). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
|
-
- HY-179081
-
-
- HY-183217C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-Biotin (MW 100 kDa) is a functional material formed by covalently linking biotin to dextran molecules. Dextran-Biotin combines the biocompatibility of dextran with the high affinity of biotin for streptavidin, and is widely used in research fields such as biolabeling, detection, drug delivery, and neural tracking.
|
-
- HY-183217E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-Biotin (MW 500 kDa) is a functional material formed by covalently linking biotin to dextran molecules. Dextran-Biotin combines the biocompatibility of dextran with the high affinity of biotin for streptavidin, and is widely used in research fields such as biolabeling, detection, drug delivery, and neural tracking.
|
-
- HY-183217D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-Biotin (MW 250 kDa) is a functional material formed by covalently linking biotin to dextran molecules. Dextran-Biotin combines the biocompatibility of dextran with the high affinity of biotin for streptavidin, and is widely used in research fields such as biolabeling, detection, drug delivery, and neural tracking.
|
-
- HY-183217B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-Biotin (MW 70 kDa) is a functional material formed by covalently linking biotin to dextran molecules. Dextran-Biotin combines the biocompatibility of dextran with the high affinity of biotin for streptavidin, and is widely used in research fields such as biolabeling, detection, drug delivery, and neural tracking.
|
-
- HY-183217
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-Biotin (MW 10 kDa) is a functional material formed by covalently linking biotin to dextran molecules. Dextran-Biotin combines the biocompatibility of dextran with the high affinity of biotin for streptavidin, and is widely used in research fields such as biolabeling, detection, drug delivery, and neural tracking.
|
-
- HY-183217A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-Biotin (MW 40 kDa) is a functional material formed by covalently linking biotin to dextran molecules. Dextran-Biotin combines the biocompatibility of dextran with the high affinity of biotin for streptavidin, and is widely used in research fields such as biolabeling, detection, drug delivery, and neural tracking.
|
-
- HY-186128
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-NH2 (MW 40000) is a functional polysaccharide derivative that has been chemically modified to introduce amino (-NH2) active groups onto the molecular chain of natural dextran. Dextran-NH2 (MW 40000) can be used as a drug delivery vehicle and a bioconjugation label.
|
-
- HY-150352C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-COOH (MW 100 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
|
-
- HY-150352D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-COOH (MW 250 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
|
-
- HY-150352A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-COOH (MW 10 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
|
-
- HY-150352E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-COOH (MW 500 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
|
-
- HY-150352B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-COOH (MW 70 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
|
-
- HY-158227A
-
|
DexMA (MW 500000)
|
Biochemical Assay Reagents
|
Others
|
Dextran Methacryloyl (MW 500000) is a methacryloyl dextran that converts into cell matrix gels. Dextran Methacryloyl (MW 500000) formed gels that had no cytotoxic effects on fibroblasts, but cells adhered only inefficiently in long-term experiments . Dextran Methacryloyl (MW 500000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity. Application: cell culture, biological 3D printing, tissue engineering, etc.
|
-
- HY-182663A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-NH2 (MW 10 kDa) is a functional polysaccharide derivative that has been chemically modified to introduce amino (-NH2) active groups onto the molecular chain of natural dextran. Dextran-NH2 (MW 10 kDa) can be used as a drug delivery vehicle and a bioconjugation label.
|
-
- HY-182663E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-NH2 (MW 500 kDa) is a functional polysaccharide derivative that has been chemically modified to introduce amino (-NH2) active groups onto the molecular chain of natural dextran. Dextran-NH2 (MW 500 kDa) can be used as a drug delivery vehicle and a bioconjugation label.
|
-
- HY-182663B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-NH2 (MW 70 kDa) is a functional polysaccharide derivative that has been chemically modified to introduce amino (-NH2) active groups onto the molecular chain of natural dextran. Dextran-NH2 (MW 70 kDa) can be used as a drug delivery vehicle and a bioconjugation label.
|
-
- HY-182663D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-NH2 (MW 250 kDa) is a functional polysaccharide derivative that has been chemically modified to introduce amino (-NH2) active groups onto the molecular chain of natural dextran. Dextran-NH2 (MW 250 kDa) can be used as a drug delivery vehicle and a bioconjugation label.
|
-
- HY-182663C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dextran-NH2 (MW 100 kDa) is a functional polysaccharide derivative that has been chemically modified to introduce amino (-NH2) active groups onto the molecular chain of natural dextran. Dextran-NH2 (MW 100 kDa) can be used as a drug delivery vehicle and a bioconjugation label.
|
-
- HY-P2840A
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Dextranase, Penicillium sp. (EC 3.2.1.11) hydrolyzes-(1,6)-glucosidic linkages in dextran. Dextranase, Penicillium sp. (EC 3.2.1.11) has been used for hydrolyzing dextran at sugar mills in order to improve efficiency of sugar production.
|
-
- HY-128868I
-
|
|
Biochemical Assay Reagents
|
Others
|
|
FITC-Dextran (MW 2000000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments.
|
-
- HY-128868J
-
|
|
Biochemical Assay Reagents
|
Others
|
|
FITC-Dextran (MW 1000) is a compound that belongs to the class of fluorescent dyes. It is often used as a tracer molecule in biomedical research to label and track cells or other biological substances. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate extracted from starch. The combination of the two creates a stable fluorescent tracer that can be observed under a microscope or quantified using specialized detection instruments.
|
-
- HY-128868F
-
|
|
Biochemical Assay Reagents
|
Others
|
|
FITC-Dextran (MW 110000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments.
|
-
- HY-128868E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
FITC-Dextran (MW 70000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments.
|
-
- HY-128868C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
FITC-Dextran (MW 20000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments.
|
-
- HY-DY1016
-
|
|
Fluorescent Dye
|
Others
|
FITC-Dextran (MW 10000) (solution) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 10000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 10000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption . Solvent and Concentration: Sterile water: 2 mM
|
-
- HY-DY1018
-
|
|
Fluorescent Dye
|
Others
|
FITC-Dextran (MW 4000) (solution) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption . Solvent and Concentration: Sterile water: 2 mM
|
-
- HY-148140
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cross-linked dextran G 25 is a dextran chromatography medium. Cross-linked dextran G 25 separates from 1 to 5 kD (spherical proteins) and can be used for the separation of peptides as well as for the desalting and buffer replacement of large molecule proteins .
|
-
- HY-W134327
-
|
Diethylaminoethyl Dextran (MW 40000)
|
Biochemical Assay Reagents
|
Others
|
|
DEAE-Dextran (MW 40000) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-128868B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
FITC-Dextran (MW 3000-5000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 3000-5000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 3000-5000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption . Storage: protect from light.
|
-
- HY-107928B
-
-
- HY-D2706
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 3000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2712
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 500000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2708
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 10000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2705
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 2000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2710
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 40000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2707
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 5000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2711
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 100000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2466
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
|
|
Cy3 Dextran (MW 70000) is a fluorescent labeling reagent that conjugates the Cy3 (HY-D0822) fluorescent dye with Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Dextran inhibits platelet aggregation and coagulation factors, and serves as a plasma volume expander .
|
-
- HY-D2709
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 20000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-DY1103
-
|
|
Biochemical Assay Reagents
|
Others
|
FITC-Dextran (MW 70000) (solution) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments. Solvent and concentration: ddH2O: 1 mM
|
-
- HY-103703
-
|
|
Anion Exchangers
|
Metabolic Disease
Inflammation/Immunology
|
|
DEAE Cross-linked dextran A 25 is a weak anion exchange chromatography packing material. DEAE Cross-linked dextran A 25 can be used for the analysis of trace metal humic acid complexes in river water and the purification of biomacromolecules. DEAE Cross-linked dextran A 25 can also be used for research on diseases related to abnormal AVP levels .
|
-
- HY-148139
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cross-linked dextran G 75 is a Gel-filtration media. Cross-linked dextran G 75 also is a dextran-based matrix and used for Gel-filtration chromatography (Particle size range: 40-120 μm; Sphere protein separation range: 3K-80K Da; Polysaccharide separation range: 1K-50K Da) .
|
-
- HY-D3047A
-
|
|
Fluorescent Dye
|
Others
|
|
Rhodamine B-Dextran (MW 5000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 5000. Rhodamine B-Chitosan (MW 5000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-D3047
-
|
|
Fluorescent Dye
|
Others
|
|
Rhodamine B-Dextran (MW 3000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 3000. Rhodamine B-Chitosan (MW 3000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-D3047H
-
|
|
Fluorescent Dye
|
Others
|
|
Rhodamine B-Dextran (MW 200000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 200,000. Rhodamine B-Chitosan (MW 200000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-D3047C
-
|
|
Fluorescent Dye
|
Others
|
|
Rhodamine B-Dextran (MW 20000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 20,000. Rhodamine B-Chitosan (MW 20000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-D3047I
-
|
|
Fluorescent Dye
|
Others
|
|
Rhodamine B-Dextran (MW 500000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 500,000. Rhodamine B-Chitosan (MW 500000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-D3047D
-
|
|
Fluorescent Dye
|
Others
|
|
Rhodamine B-Dextran (MW 40000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 40,000. Rhodamine B-Chitosan (MW 40000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-D3047E
-
|
|
Fluorescent Dye
|
Others
|
|
Rhodamine B-Dextran (MW 100000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 100,000. Rhodamine B-Chitosan (MW 100000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-D3047B
-
|
|
Fluorescent Dye
|
Others
|
|
Rhodamine B-Dextran (MW 10000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 10,000. Rhodamine B-Chitosan (MW 10000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-138560A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cross-linked dextran G 50, medium is a gel filtration medium. Cross-linked dextran G 50, medium can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da). Cross-linked dextran G 50, medium are microspheres with an average particle size of D50 = 220-250 μm .
|
-
- HY-138560B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cross-linked dextran G 50, fine is a gel filtration medium. Cross-linked dextran G 50, fine can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da). Cross-linked dextran G 50, fineThe average particle size is D50=110-130 μmof microspheres .
|
-
- HY-172388
-
-
- HY-172388A
-
-
- HY-141483
-
-
- HY-172387A
-
-
- HY-172387
-
-
- HY-156045C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cross-linked dextran G 200 is a hydrophilic gel based on molecular size exclusion and targeted macromolecular separation. Cross-linked dextran G 200 works through the gel permeation mechanism, and the cross-linked structure forms a three-dimensional network with a specific pore size, achieving separation based on the molecular hydrodynamic volume. Cross-linked dextran G 200 can be used to adjust the osmotic solute distribution coefficient and the ability to maintain osmotic equilibrium, such as in gel filtration chromatography for purification and analysis of biomacromolecules such as proteins and nucleic acids . Cross-linked dextran G 200 can also be used as a gel filtration filler (particle size range: 40-120 μm; globular protein separation range: 5-600 kDa) .
|
-
- HY-156045B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cross-linked dextran G 150 is a hydrophilic gel based on molecular size exclusion and targeted for the separation of macromolecules. Cross-linked dextran G 150 functions through the gel permeation mechanism, where the cross-linked structure forms a three-dimensional network with specific pore diameters, achieving separation based on the molecular volumetric flow. Cross-linked dextran G 150 can be used to regulate the distribution coefficient of permeating solutes and maintain the permeation balance, such as in gel filtration chromatography for the purification and analysis of biological macromolecules like proteins and nucleic acids. Cross-linked dextran G 150 can also be used as a gel filtration filler (particle size range: 40-120 μm; spherical protein separation range: 5-300 kDa) .
|
-
- HY-148140B
-
-
- HY-148140A
-
-
- HY-141522A
-
-
- HY-148140C
-
-
- HY-148139A
-
-
- HY-138560
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cross-linked dextran G 50 is a gel filtration medium. Cross-linked dextran G 50 can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da) .
|
-
- HY-164416
-
|
|
Drug Intermediate
|
Inflammation/Immunology
|
|
DBCO-Dextran sulfate (MW 40000) can be used to construct DS-EXOs in cells via click chemistry, that can be used for the research of rheumatoid arthritis (RA) .
|
-
- HY-107928A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Iron-Dextran is an injectable complex of iron and dextran, a complex carbohydrate. It is often used to improve iron deficiency anemia, a condition characterized by low levels of iron in the blood due to insufficient dietary intake or malabsorption. Iron-glucan works by providing a source of supplemental iron that the body can use to produce hemoglobin, the protein responsible for carrying oxygen in the blood. However, caution should be exercised when taking iron dextran because it may cause hypersensitivity reactions, including anaphylaxis, and may also increase the risk of infection or other adverse reactions. Therefore, it should only be administered under the supervision of a qualified healthcare provider in a clinical setting.
|
-
- HY-158082E
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 500000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran, MW 500000 (Tetramethyl rhodamine isothiocyanate glucan, MW 500000) is a fluorescent dye, with the molecular weight of 500 kD. TRITC-dextran, MW 500000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 500000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 500000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-158082D
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 150000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran, MW 150000 (Tetramethyl rhodamine isothiocyanate glucan, MW 150000) is a fluorescent dye, with the molecular weight of 150 kD. TRITC-dextran, MW 150000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 150000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 150000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-158082H
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 2000000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran, MW 2000000 (Tetramethyl rhodamine isothiocyanate glucan, MW 2000000) is a fluorescent dye, with the molecular weight of 2000 kD. TRITC-dextran, MW 2000000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 2000000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 2000000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-138638
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cross-linked dextran LH 20 could be used for the isolation and purification of natural compounds and foods, such as red wine, pigments, and flavonoids .
|
-
- HY-158082
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 4000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran MW 4000 (Tetramethyl rhodamine isothiocyanate glucan, MW 4000) is a fluorescent dye, with the molecular weight of 4 kD. TRITC-dextran MW 4000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 4000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 4000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-158082B
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 40000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran, MW 40000 (Tetramethyl rhodamine isothiocyanate glucan, MW 40000) is a fluorescent dye, with the molecular weight of 40 kD. TRITC-dextran MW 40000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 40000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 40000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-158082A
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 20000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran, MW 20000 (Tetramethyl rhodamine isothiocyanate glucan, MW 20000) is a fluorescent dye, with the molecular weight of 20 kD. TRITC-dextran MW 20000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 20000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 20000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-156045
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cross-linked dextran G 15 is a hydrophilic gel that can be used as a gel filter filler (Sphere protein separation range: >1500 Da; Polysaccharide separation range: >1500 Da) .
|
-
- HY-156045A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cross-linked dextran G 10 is a weak cation exchanger and a hydrophilic gel that can be used as a gel filter filler (Sphere protein separation range: >700 Da; Polysaccharide separation range: >700 Da) .
|
-
- HY-141522
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cross-linked dextran G 100 is a gel filtration medium that can be used for protein purification (Sphere protein separation range: 4K-150K Da; Polysaccharide separation range: 1K-100K Da) .
|
-
- HY-108622
-
|
Daxalipram
|
Phosphodiesterase (PDE)
Interleukin Related
IFNAR
|
Inflammation/Immunology
|
|
Mesopram (Daxalipram) is an orally active phosphodiesterase (PDE) 4 inhibitor. Mesopram inhibits the synthesis of proinflammatory cytokines TNF-α and IFN-γ. Mesopram demonstrates efficacy in ameliorating Dextran sulfate sodium (DSS) (HY-116282C)-induced murine colitis. Mesopram can be used for the study of chronic inflammatory diseases .
|
-
- HY-N1388
-
|
|
Others
|
Inflammation/Immunology
|
|
Tussilagone, a major active component in Tussilago farfara, has anti-inflammatory effect. Tussilagone ameliorates inflammatory responses in dextran sulphate sodium-induced murine colitis. Tussilagone inhibits the inflammatory response and improves survival in cecal ligation and puncture (CLP)-induced septic mice .
|
-
- HY-N1388R
-
|
|
Reference Standards
Others
|
Inflammation/Immunology
|
|
Tussilagone (Standard) is the analytical standard of Tussilagone. This product is intended for research and analytical applications. Tussilagone, a major active component in Tussilago farfara, has anti-inflammatory effect. Tussilagone ameliorates inflammatory responses in dextran sulphate sodium-induced murine colitis. Tussilagone inhibits the inflammatory response and improves survival in cecal ligation and puncture (CLP)-induced septic mice .
|
-
- HY-111662
-
|
|
NOD-like Receptor (NLR)
|
Inflammation/Immunology
|
|
Fc 11a-2, a benzimidazole compound, is an orally active and potent NLRP3 inflammasome inhibitor. Fc 11a-2 restrains the formation of NLRP3 inflammasome by inhibiting activation of caspase-1 and thus the activation of IL-1b/IL-18. Fc 11a-2 prevents the development of Dextran sulfate sodium (DSS; HY-116282C)-induced murine experimental colitis .
|
-
- HY-E71209
-
|
|
Biochemical Assay Reagents
|
Others
|
|
α-1,3-Glucan synthase (EC 2.4.1.183) requires a dextran primer to initiate the reaction, which leads to the elongation of the dextran chain.
|
-
- HY-181485
-
|
|
GPR68
TNF Receptor
Interleukin Related
|
Inflammation/Immunology
|
|
GPR68 antagonist 1 is a GPR68 antagonist with an IC50 of 81 nM. GPR68 antagonist 1 inhibits the mouse GPR68-mediated cAMP signaling pathway with an IC50 of 179 nM. GPR68 antagonist 1 alleviates disease symptoms in a dextran sulfate sodium (DSS) (HY-116282C)-induced mouse model of inflammatory bowel disease. GPR68 antagonist 1 is applicable to research related to inflammatory bowel disease .
|
-
- HY-112624F4
-
-
- HY-N0913A
-
-
- HY-N2478
-
|
|
Autophagy
Parasite
|
Inflammation/Immunology
|
|
Taraxasteryl acetate is isolated from P. sagittalis,and has a broad spectrum of anti-inflammatory activity. Taraxasterol acetate promotes RNF31 degradation by activating autophagy. Taraxasteryl acetate relieves dextran, zymosan and arachidonic acid induced rat hind-paw edema. Taraxasteryl acetate can be used for the topical inflammation treatment [1] [2] .
|
-
- HY-114766
-
|
|
Phosphodiesterase (PDE)
|
Inflammation/Immunology
|
|
Pumafentrine is an orally active, potent dual PDE3/PDE4 inhibitor. Pumafentrine dose-dependently ameliorates the clinical score and colonic TNFα production in murine Dextran sulphate sodium (DSS; HY-116282C)-induced colitis in a preventive setting .
|
-
- HY-P990163
-
|
|
Transmembrane Glycoprotein
|
Inflammation/Immunology
|
|
Anti-Mouse Siglec-H Antibody (440c) is a rat-derived IgG2b type antibody inhibitor, targeting to mouse Siglec-H. Anti-Mouse Siglec-H Antibody (440c) recognizes sialic acid-binding immunoglobulin (Ig)-like lectin family (Siglec-H) selectively expressing on plasmacytoid DCs and interferon–producing cells. Anti-Mouse Siglec-H Antibody (440c) can be used for the researches of inflammation and immunology, such as colitis .
|
-
- HY-150612
-
|
|
p38 MAPK
|
Cancer
|
|
(R)-STU104 is a potent and orally active TAK1-MKK3 interaction inhibitor with IC50s of 0.58 μM and 4.0 μM for TNF-α and MKK3 phosphorylation. (R)-STU104 suppresses the TAK1/MKK3/p38/MnK1/MK2/elF4E signal pathways through binding with MKK3 and disrupting the TAK1 phosphorylating MKK3. (R)-STU104 can be used for researching ulcerative colitis .
|
-
- HY-N0278
-
|
Pulsatilla camphor; Anemonine; trans-Anemonin
|
PKC
NO Synthase
|
Inflammation/Immunology
|
|
Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases .
|
-
- HY-158403
-
|
|
METTL3
|
Inflammation/Immunology
|
|
METTL3-IN-7 (7460-0250) is a potent METTL3 inhibitor. METTL3-IN-7 strongly ameliorates Dextran sulfate sodium salt (DSS) (HY-116282C)-induced colitis. METTL3-IN-7 can be used Inflammatory bowel disease (IBD) research .
|
-
- HY-118704
-
|
|
mTOR
|
Inflammation/Immunology
Cancer
|
|
P-2281 is a mTOR inhibitor with anticancer and anti-inflammatory efficacies. P2281 inhibits mTOR activity in colon cancer cells. P-2281 suppresses Dextran sulfate sodium salt (HY-116282C) (DSS)-induced colitis by inhibiting T cell function and is efficacious in a murine model of human colitis .
|
-
- HY-158404
-
|
|
METTL3
|
Inflammation/Immunology
|
|
METTL3-IN-8 (F039-0002) is a potent METTL3 inhibitor. METTL3-IN-8 strongly ameliorates Dextran sulfate sodium salt (DSS) (HY-116282C)-induced colitis. METTL3-IN-8 can be used Inflammatory bowel disease (IBD) research .
|
-
- HY-168567
-
|
|
RIP kinase
NF-κB
p38 MAPK
|
Inflammation/Immunology
|
|
RIPK2-IN-6 (Compound 15a) is an inhibitor for RIPK, that inhibits the phosphorylation of RIPK2, and thus inhibits the NF-κB and MAPK signaling pathways. RIPK2-IN-6 exhibits anti-inflammatory and anti-fibrotic activities in Dextran sodium sulfate (HY-116282C)-induced mice colitis models .
|
-
- HY-107062
-
|
|
Histamine Receptor
|
Inflammation/Immunology
|
|
AA 344 is an orally active antiallergic agent. AA 344 inhibits the IgE, IgGa, Concanavalin A (HY-P2149), Dextran -mediated release of histamine. AA 344 shows inhibitory effects on the homologous passive cutaneous anaphylaxis and the passive systemic anaphylaxis in guinea pigs. AA 344 selectively suppresses the type I allergic reaction .
|
-
- HY-162588
-
|
|
NOD-like Receptor (NLR)
ATTECs
Autophagy
|
Inflammation/Immunology
|
|
MC-ND-18 is an ATTEC degrader that degrades NLRP3 via the Autophagy pathway, with a DC50 of 125.5 nM in THP-1 cells. MC-ND-18 exhibits anti-inflammatory activity in a DSS-induced mouse model of colitis. MC-ND-18 can be used for research on inflammatory bowel disease. MC-ND-18 consists of an NLRP3 inhibitor (HY-156121), a linker (HY-W018745), and an LC3 ligand .
|
-
- HY-N2478R
-
|
|
Autophagy
Reference Standards
|
Inflammation/Immunology
|
|
Taraxasteryl acetate (Standard) is the analytical standard of Taraxasteryl acetate. This product is intended for research and analytical applications. Taraxasteryl acetate is isolated from P. sagittalis,and has a broad spectrum of anti-inflammatory activity. Taraxasterol acetate promotes RNF31 degradation by activating autophagy. Taraxasteryl acetate relieves dextran, zymosan and arachidonic acid induced rat hind-paw edema. Taraxasteryl acetate can be used for the topical inflammation treatment .
|
-
- HY-151252
-
|
|
Proteasome
NOD-like Receptor (NLR)
|
Inflammation/Immunology
|
|
NIC-0102 is an orally active proteasome inhibitor (pIC50=7.55) that specifically inhibits NLRP3 inflammatory vesicle activation. NIC-0102 shows potent anti-inflammatory effects in a model of dextran sulfate sodium (DSS)-induced ulcerative colitis. NIC-0102 also inhibits production of pro-IL-1β .
|
-
- HY-D2421
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
Cancer
|
|
DEAE-dex-Cy5 is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, Dextran (dex) and Diethylaminoethyl (DEAE). Cy5 is a Cyanine dye (with a long wavelength about 662nm) that can be used for molecular labeling and microscopy imaging. Dex has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander .
|
-
- HY-N0278A
-
|
(Rac)-Pulsatilla camphor; (Rac)-Anemonine
|
PKC
NO Synthase
|
Inflammation/Immunology
|
|
(Rac)-Anemonin ((Rac)-Pulsatilla camphor) is the diastereoisomer of Anemonin (HY-N0278). Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases .
|
-
- HY-175222
-
-
- HY-118984
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
CRX-526 is a TLR4 antagonist that can block the interaction of lipopolysaccharide (LPS, HY-D1056) with the immune system, including preventing the expression of pro-inflammatory genes stimulated by LPS, as well as blocking the release of TNF-α induced by LPS. CRX-526 exhibits anti-inflammatory effects in two mouse models of colitis (namely, the dextran sodium sulfate-induced colitis model and the multidrug resistance gene 1a-deficient mouse model) .
|
-
- HY-163102
-
|
|
TNF Receptor
NF-κB
|
Inflammation/Immunology
|
|
IA-14069 is an orally active tumor necrosis factor-α (TNF-α) inhibitor. IA-14069 binds directly to TNF-α and TNF-α-triggered signaling (p-IκBα and NF-κB p65) activities. Additionally, IA-14069 exerts a suppressive effect on Dextran sodium sulfate (HY-116282C) (DSS)-induced colitis. IA-14069 can be used for the research of Rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) .
|
-
- HY-155199
-
|
|
Phosphodiesterase (PDE)
|
Inflammation/Immunology
|
|
PDE1-IN-5 (Compound 10c) is a selective PDE1C inhibitor (IC50: 15 nM). PDE1-IN-5 has anti- inflammatory activity, and inhibits expression of iNOS, TNF-α, IL-1α, IL-1β, and IL-6 induced by LPS. PDE1-IN-5 has anti-inflammatory bowel disease (IBD) effects in the dextran sodium sulfate (DSS)-Induced colitis mice model. PDE1-IN-5 can be used for research of IBD .
|
-
- HY-183578
-
|
|
LPL Receptor
|
Inflammation/Immunology
|
|
TYY-31 is an orally active, selective S1PR1 agonist with an EC50 of 1.13 pM. TYY-31 promotes the phosphorylation of ERK1/2. TYY-31 exerts anti-inflammatory and immunosuppressive effects, ameliorates DSS-induced colitis in mice, and reduces peripheral blood lymphocyte counts in mice in a dose-dependent manner. TYY-31 can be used for the research of ulcerative colitis .
|
-
- HY-155998
-
|
|
NF-κB
|
Inflammation/Immunology
|
|
NF-κB-IN-11 (Compound 3i) is a NF-κB inhibitor. NF-κB-IN-11 inhibits TNF-α induced activation of NF-κB pathway, and inhibits nuclear translocation of NF-κB. NF-κB-IN-11 down-regulates the expression levels of phosphor-IKK, IκBα, and NF-κB p65. NF-κB-IN-11 has anti-inflammatory activity, and alleviates dextran sulfate sodium-induced colitis in mice. NF-κB-IN-11 (p.o.) shows a MTD more than 1852 mg/kg in mice acute toxicity assay .
|
-
- HY-159179
-
|
|
Integrin
|
Inflammation/Immunology
|
|
α4 integrin receptor antagonist 3 (Compound 11) is an orally active α4integrin receptor antagonist. α4 integrin receptor antagonist 3 can inhibit the adhesion of K562 cells mediated by the interaction between α4β1/VCAM-1 and α4β7/MAdCAM-1, with IC50 values of 130 nM and 2 nM, respectively. α4 integrin receptor antagonist 3 has the potential to be used in the study of dextran sulfate sodium (DSS) colitis mouse model .
|
-
- HY-181875
-
|
|
LPL Receptor
|
Inflammation/Immunology
|
|
S1PR1/S1PR5 agonist-1 (Compound 19) is an orally active S1PR1 and S1PR5 agonist with EC50 values of 40.0 and 22.9 nM, respectively. S1PR1/S1PR5 agonist-1 binds to key residues of S1PR1 to mediate agonistic activity. S1PR1/S1PR5 agonist-1 alleviates colitis pathological changes in DSS-induced mouse models and exerts minimal effects on mouse heart rate. S1PR1/S1PR5 agonist-1 can be used for the research of inflammatory bowel disease .
|
-
- HY-N0648
-
|
|
Interleukin Related
Keap1-Nrf2
Heme Oxygenase (HO)
NF-κB
Apoptosis
|
Inflammation/Immunology
|
|
Monotropein is an iridoid glycoside that can be isolated from the roots of Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model. Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes. Monotropein has cartilage protective activity. Monotropein can alleviate Cisplatin (HY-17394)-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis through activation of Nrf2/HO-1 pathway and inhibition of NF-κB signaling. Monotropein can be studied in research for osteoarthritis, acute kidney injury and acute lung injury .
|
-
- HY-178761
-
|
|
Phosphoglycerate Kinase (PGK)
Keap1-Nrf2
Heme Oxygenase (HO)
Interleukin Related
|
Inflammation/Immunology
|
|
PGK1-IN-1 (Compound 6e) is a potent and selective PGK1 inhibitor (IC50: 33 nM). PGK1-IN-1 inhibits PGK1-mediated glycolytic metabolism and reduces glucose consumption/lactate production. PGK1-IN-1 enhances Nrf2 accumulation and HO-1 expression, and suppresses the transcription and protein levels of the inflammatory cytokines IL-1β and IL-6. PGK1-IN-1 ameliorates Dextran sulfate sodium (DSS) (HY-116282C)-induced experimental colitis in mice. PGK1-IN-1 can be used for research of inflammatory bowel disease (IBD) .
|
-
- HY-N16021
-
|
|
Toll-like Receptor (TLR)
Cdc42-binding kinase
Galectin
|
Inflammation/Immunology
|
|
4A-MPLA ammonium is an orally active TLR4 agonist. 4A-MPLA ammonium induces TLR4 endocytosis dependent on Cdc42 and galectin-3, triggering TRIF-mediated signaling and sustained IFN-β production. 4A-MPLA ammonium promotes lipid droplet formation, upregulates interferon-stimulated genes and type I IFN signaling genes, downregulates lysosome/phagosome function genes, and modulates tolerogenic dendritic cell function. 4A-MPLA ammonium can be used for the research of colitis .
|
-
- HY-N0648R
-
|
|
Reference Standards
Interleukin Related
Heme Oxygenase (HO)
Keap1-Nrf2
NF-κB
Apoptosis
|
Inflammation/Immunology
|
|
Monotropein (Standard) is the analytical standard of Monotropein. This product is intended for research and analytical applications. Monotropein is an iridoid glycoside that can be isolated from the roots of Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model. Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes. Monotropein has cartilage protective activity. Monotropein can alleviate Cisplatin (HY-17394)-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis through activation of Nrf2/HO-1 pathway and inhibition of NF-κB signaling. Monotropein can be studied in research for osteoarthritis, acute kidney injury and acute lung injury .
|
-
- HY-N0847
-
Micheliolide
Maximum Cited Publications
8 Publications Verification
|
NF-κB
PI3K
Akt
TGF-beta/Smad
|
Inflammation/Immunology
Cancer
|
|
Micheliolide is a sesquiterpene lactone with anti-cancer and anti-inflammatory effects, which is derived from Michelia compressa and Michelia champaca. Micheliolide can attenuate high glucose-stimulated NF-κB activation, IκBα degradation, and the expression of MCP-1, TGF-β1, and FN in mouse mesangial cells. Micheliolide inhibits LPS (HY-D1056)-induced activation of NF-κB and PI3K/Akt/p70S6K pathways to play an anti-inflammatory role. Micheliolide inhibits dextran sodium sulphate (DSS) (HY-116282)-induced inflammatory intestinal disease, colitis-associated cancer and rheumatic arthritis .
|
-
- HY-N0847R
-
|
|
Reference Standards
NF-κB
PI3K
Akt
TGF-beta/Smad
|
Inflammation/Immunology
Cancer
|
|
Micheliolide is a sesquiterpene lactone with anti-cancer and anti-inflammatory effects, which is derived from Michelia compressa and Michelia champaca. Micheliolide can attenuate high glucose-stimulated NF-κB activation, IκBα degradation, and the expression of MCP-1, TGF-β1, and FN in mouse mesangial cells. Micheliolide inhibits LPS (HY-D1056)-induced activation of NF-κB and PI3K/Akt/p70S6K pathways to play an anti-inflammatory role. Micheliolide inhibits dextran sodium sulphate (DSS) (HY-116282)-induced inflammatory intestinal disease, colitis-associated cancer and rheumatic arthritis .
|
-
- HY-113227
-
|
|
Endogenous Metabolite
|
Inflammation/Immunology
|
|
Oxoadipic acid is a key intermediate metabolite in the lysine degradation pathway. The level of Oxoadipic acid is significantly negatively correlated with the abundance of Staphylococcus. That is, the higher the abundance of Staphylococcus-a potential pathogenic bacterium that usually increases in ulcerative colitis-the lower the level of Oxoadipic acid. Oxoadipic acid can be used in the research of ulcerative colitis .
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-
- HY-182268
-
|
|
Bacterial
Interleukin Related
TNF Receptor
|
Infection
Inflammation/Immunology
|
|
Antibiofilm agent-21 is an orally active prodrug of Antibiofilm agent-20 (HY-182268) with glucuronidation. Antibiofilm agent-21 avoids absorption in the small intestine via reduced membrane permeability, improving colon delivery rate, and converts to its active form in the colon. Antibiofilm agent-21 increases colon length and reduces IL-17 and TNF-α levels in a murine DSS (HY-116282C)-induced colitis model. Antibiofilm agent-21 can be used for the research of inflammatory bowel disease .
|
-
- HY-165557
-
|
|
P2X Receptor
|
Inflammation/Immunology
|
|
GSK1370319A (compound 1a) is a human P2X7 receptor inhibitor with an IC50 of 474 nM and a Ki of 176 nM. GSK1370319A inhibits the production of IL-1β, reduces the generation of reactive oxygen species (ROS), and increases the survival rate of macrophages. GSK1370319A can be used for the research of inflammatory bowel disease .
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-
- HY-123115
-
|
5-O-α-D-Glucopyranosyl-D-fructose
|
JAK
STAT
TNF Receptor
Interleukin Related
|
Metabolic Disease
Inflammation/Immunology
|
|
Leucrose (5-O-α-D-Glucopyranosyl-D-fructose) is an orally active Sucrose (HY-B1779) isomer naturally found in pollen and honey. Leucrose promotes phosphorylation of JAK1 and STAT6, reduces pro-inflammatory mediators and cytokinesas (TNFα, and IL-1β), increases M2 macrophage polarization and suppresses DSS (HY-116282C)-induced colitis. Leucrose suppresses hepatic triglyceride accumulation, improves fasting blood glucose levels, and regulates hepatic lipogenesis and fatty acid β-oxidation in high-fat diet-induced obese mice. Leucrose is slowly hydrolyzed into glucose and fructose by α-glucosidase and acts as as a sugar substitute in diet .
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-
| Cat. No. |
Product Name |
Type |
-
- HY-128868A
-
|
|
Fluorescent Dye
|
|
FITC-Dextran (MW 4000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
|
-
- HY-128868
-
|
|
Fluorescent Dye
|
|
FITC-Dextran (MW 10000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 10000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 10000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
|
-
- HY-128868D
-
|
|
Fluorescent Dye
|
|
FITC-Dextran (MW 40000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 40000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 40000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
|
-
- HY-128868E
-
|
|
Fluorescent Dye
|
|
FITC-Dextran (MW 70000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments.
|
-
- HY-128868I
-
|
|
Fluorescent Dye
|
|
FITC-Dextran (MW 2000000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments.
|
-
- HY-128868B
-
|
|
Fluorescent Dye
|
|
FITC-Dextran (MW 3000-5000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 3000-5000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 3000-5000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption . Storage: protect from light.
|
-
- HY-128868G
-
|
|
Fluorescent Dye
|
|
FITC-Dextran (MW 150000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=491 nm; Em=518 nm). FITC-Dextran (MW 150000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 150000) can be used in perfusion studies in animals or in fluorescence microlymphography, to study processes that affect the permeability of the blood brain barrier (BBB) . FITC-Dextran (MW 150000) can be used as fluorescent probe to study cell permeability .
|
-
- HY-128868C
-
|
|
Fluorescent Dye
|
|
FITC-Dextran (MW 20000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments.
|
-
- HY-128868H
-
|
|
Fluorescent Dye
|
|
FITC-Dextran (MW 500000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments.
|
-
- HY-158082C
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 70000
|
Fluorescent Dye
|
|
TRITC-dextran MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye with a molecular weight of 70 kD. The excitation wavelength of TRITC-dextran MW 70000 is 555 nm, and its emission wavelength is 570 nm. TRITC-dextran MW 70000 is used for drug delivery because TRITC maintains stability over a wide pH range (i.e., pH 2-11) and exhibits photobleaching resistance .
|
-
- HY-DY1016
-
|
|
Fluorescent Dye
|
FITC-Dextran (MW 10000) (solution) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 10000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 10000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption . Solvent and Concentration: Sterile water: 2 mM
|
-
- HY-112624F1
-
|
|
Fluorescent Dye
|
|
CY5-Dextran (MW 4000) is a fluorescent dye CY5 (HY-D0821)-labeled Dextran (HY-112624). Dextran-CY5 (MW 4000) can be used to visualize the specific subcellular distribution of dextran at the nanoscale .
|
-
- HY-128868J
-
|
|
Fluorescent Dye
|
|
FITC-Dextran (MW 1000) is a compound that belongs to the class of fluorescent dyes. It is often used as a tracer molecule in biomedical research to label and track cells or other biological substances. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate extracted from starch. The combination of the two creates a stable fluorescent tracer that can be observed under a microscope or quantified using specialized detection instruments.
|
-
- HY-128868F
-
|
|
Fluorescent Dye
|
|
FITC-Dextran (MW 110000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments.
|
-
- HY-112624F
-
|
|
Fluorescent Dye
|
|
CY7-Dextran (MW 4000) is a fluorescent dye that consists of CY7 (HY-D0825) and Dextran (HY-112624) (Ex=740 nm; Em=770 nm). CY7-Dextran (MW 4000) can be used as a cell volume indicator and delineates the thin peripheral edges of the cells .
|
-
- HY-D2709
-
|
|
Fluorescent Dye
|
|
Cy3 Dextran (MW 20000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-158082A
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 20000
|
Fluorescent Dye
|
|
TRITC-dextran, MW 20000 (Tetramethyl rhodamine isothiocyanate glucan, MW 20000) is a fluorescent dye, with the molecular weight of 20 kD. TRITC-dextran MW 20000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 20000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 20000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-D2465
-
|
|
Fluorescent Dye
|
|
CY5-Dextran is a fluorescent dye CY5 (HY-D0821)- labeled Dextran (HY-112624). CY5 exhibits a maximal excitation wavelength of 633 nm, and a maximal emission wavelength of 670 nm. Dextran-CY5 can be used to visualize the specific subcellular distribution of dextran at the nanoscale .
|
-
- HY-D2708
-
|
|
Fluorescent Dye
|
|
Cy3 Dextran (MW 10000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-DY1018
-
|
|
Fluorescent Dye
|
FITC-Dextran (MW 4000) (solution) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption . Solvent and Concentration: Sterile water: 2 mM
|
-
- HY-D2466
-
|
|
Fluorescent Dye
|
|
Cy3 Dextran (MW 70000) is a fluorescent labeling reagent that conjugates the Cy3 (HY-D0822) fluorescent dye with Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Dextran inhibits platelet aggregation and coagulation factors, and serves as a plasma volume expander .
|
-
- HY-D2460
-
|
|
Fluorescent Dye
|
|
Dextran-CY5.5 is a CY5.5 (HY-D0924) labeled Dextran (HY-112624) conjugate. CY5.5 is a Cyanine dye (The excitation wavelength is usually 673 nm and the emission wavelength is 707 nm) that can be used for the labeling of proteins, antibodies and small molecular compounds. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander .
|
-
- HY-D2706
-
|
|
Fluorescent Dye
|
|
Cy3 Dextran (MW 3000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2460A
-
|
|
Fluorescent Dye
|
|
Dextran-CY5.5 (MW 10000) is a CY5.5 (HY-D0924) labeled Dextran (HY-112624) conjugate. CY5.5 is a Cyanine dye (The excitation wavelength is usually 673 nm and the emission wavelength is 707 nm) that can be used for the labeling of proteins, antibodies and small molecular compounds. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander .
|
-
- HY-D2460B
-
|
|
Fluorescent Dye
|
|
Dextran-CY5.5 (MW 40000) is a CY5.5 (HY-D0924) labeled Dextran (HY-112624) conjugate. CY5.5 is a Cyanine dye (The excitation wavelength is usually 673 nm and the emission wavelength is 707 nm) that can be used for the labeling of proteins, antibodies and small molecular compounds. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander .
|
-
- HY-D2710
-
|
|
Fluorescent Dye
|
|
Cy3 Dextran (MW 40000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2711
-
|
|
Fluorescent Dye
|
|
Cy3 Dextran (MW 100000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2429
-
|
|
Fluorescent Dye
|
|
Dextran-PEG-Cy3 is the Cy3 (HY-D0822)-labeled Dextran-PEG conjugate. Dextran-PEG is used as polymer-polymer systems for the high biocompatibility to maintain cell osmolarity. Dextran-PEG coatings can reduce nanoparticle cytotoxicity .
|
-
- HY-D2712
-
|
|
Fluorescent Dye
|
|
Cy3 Dextran (MW 500000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2705
-
|
|
Fluorescent Dye
|
|
Cy3 Dextran (MW 2000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2707
-
|
|
Fluorescent Dye
|
|
Cy3 Dextran (MW 5000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2421
-
|
|
Fluorescent Dye
|
|
DEAE-dex-Cy5 is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, Dextran (dex) and Diethylaminoethyl (DEAE). Cy5 is a Cyanine dye (with a long wavelength about 662nm) that can be used for molecular labeling and microscopy imaging. Dex has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander .
|
-
- HY-DY1103
-
|
|
Fluorescent Dye
|
FITC-Dextran (MW 70000) (solution) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments. Solvent and concentration: ddH2O: 1 mM
|
-
- HY-D3047A
-
|
|
Fluorescent Dye
|
|
Rhodamine B-Dextran (MW 5000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 5000. Rhodamine B-Chitosan (MW 5000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-D3047
-
|
|
Fluorescent Dye
|
|
Rhodamine B-Dextran (MW 3000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 3000. Rhodamine B-Chitosan (MW 3000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-D3047H
-
|
|
Fluorescent Dye
|
|
Rhodamine B-Dextran (MW 200000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 200,000. Rhodamine B-Chitosan (MW 200000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-D3047C
-
|
|
Fluorescent Dye
|
|
Rhodamine B-Dextran (MW 20000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 20,000. Rhodamine B-Chitosan (MW 20000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-D3047I
-
|
|
Fluorescent Dye
|
|
Rhodamine B-Dextran (MW 500000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 500,000. Rhodamine B-Chitosan (MW 500000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-D3047D
-
|
|
Fluorescent Dye
|
|
Rhodamine B-Dextran (MW 40000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 40,000. Rhodamine B-Chitosan (MW 40000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-D3047E
-
|
|
Fluorescent Dye
|
|
Rhodamine B-Dextran (MW 100000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 100,000. Rhodamine B-Chitosan (MW 100000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-D3047B
-
|
|
Fluorescent Dye
|
|
Rhodamine B-Dextran (MW 10000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 10,000. Rhodamine B-Chitosan (MW 10000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm) .
|
-
- HY-112624F4
-
| Cat. No. |
Product Name |
Type |
-
- HY-116282
-
|
DSS (MW 5000); DXS (MW 5000)
|
Biochemical Assay Reagents
|
|
Dextran sulfate sodium salt (DSS) (MW 5000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt (DSS) with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 5000) is an inhibitor of complement and coagulation pathways, and belongs to the glycosaminoglycans (GAG) family. Dextran sulfate sodium salt (MW 5000) acts as an anticoagulant, antiviral, and anti-lipemic agent. Dextran sulfate sodium salt (DSS) stops HIV-1 virus adsorption to host cells. Dextran sulfate sodium salt (MW 5000) prevents NK cell-mediated cytotoxicity. Dextran sulfate sodium salt (MW 5000) inhibits instant blood-mediated inflammatory reaction (IBMIR) .
|
-
- HY-112624P
-
|
Dextran 500; Dextran D500; Dextran T500(MW 440000-560000)
|
Biochemical Assay Reagents
|
|
Dextran T500 MW 500,000 (Dextran 500; Dextran D500; Dextran T500 MW 440000-560000) is a polymer of anhydroglucose with the average molecular weight of 500,000. Dextran T500 MW 500,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
|
-
- HY-112624
-
Dextran
2 Publications Verification
Dextran 40
|
Biochemical Assay Reagents
|
|
Dextran (Dextran 40) has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander.
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- HY-112624B
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Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)
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Biochemical Assay Reagents
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Dextran 70,000 is a high molecular weight polysaccharide formed by glucose linked by α-(1→6) glycosidic bonds. Dextran 70,000 can expand blood volume through colloidal osmotic pressure effect and inhibit cell adhesion and platelet aggregation through steric hindrance. At the same time, Dextran 70,000 can be used as a drug carrier to achieve targeted delivery through endocytosis. Dextran 70,000 is biologically inert and has low immunogenicity. It can be used for clinical blood volume expansion, anti-thrombotic research, and evaluation of vascular permeability in in vitro experiments. It can also be combined with fluorescent dyes for cell tracking and drug delivery research. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance.
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- HY-112624L
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Dextran 10; Dextran D10; Dextran T10(MW 8000-12000)
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Biochemical Assay Reagents
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Dextran T10 (MW 10,000) (Dextran 10) is a dehydrated glucose polymer with an average molecular weight of 10,000. Dextran T10 (MW 10,000) is composed of repeated glucose units, and it has abundant hydroxyl (-OH) groups, which can be used as a natural "magnetic marker" for chemical exchange saturation transfer (CEST) MRI imaging .
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- HY-158082C
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Tetramethyl rhodamine isothiocyanate glucan, MW 70000
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Biochemical Assay Reagents
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|
TRITC-dextran MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye with a molecular weight of 70 kD. The excitation wavelength of TRITC-dextran MW 70000 is 555 nm, and its emission wavelength is 570 nm. TRITC-dextran MW 70000 is used for drug delivery because TRITC maintains stability over a wide pH range (i.e., pH 2-11) and exhibits photobleaching resistance .
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- HY-112624A
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Dextran 1; Dextran D1; Dextran T1(MW 800-1200)
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Biochemical Assay Reagents
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Dextran T1 (Dextran 1; Dextran D1) (with a molecular weight of 1,000) is a dehydrated glucose polymer with an average molecular weight of 1,000. Dextran T1 (MW 1,000) has excellent biodegradability and biocompatibility, and can be used as a nanobody carrier scaffold and a freeze-drying protectant. Dextran T1 (MW 1,000) promotes the retention of circulating tumor cells in the capillary bed .
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- HY-112624C
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Biochemical Assay Reagents
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Dextran (MW 40000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds. Dextran has excellent solubility in water, making it useful as a viscosity modifier or stabilizer in foods, paints and adhesives. In the biomedical field, dextran is often used as a plasma expander because of its ability to increase blood volume when administered intravenously. It can also be modified to create dextran-based drug delivery systems, such as targeted nanoparticles.
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- HY-W134327A
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Diethylaminoethyl Dextran (MW 500000)
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Biochemical Assay Reagents
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DEAE-Dextran (MW 500000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds and modified with diethylaminoethyl (DEAE) groups. DEAE-Dextran is a cationic molecule that can be used as a transfection reagent to deliver nucleic acids such as DNA or RNA into cells. Its positive charge interacts with negatively charged cell membranes, facilitating the uptake of nucleic acids. DEAE-Dextran can also be used as an ion-exchange chromatography resin, allowing the separation and purification of biomolecules based on their charge.
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- HY-112624I
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Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)
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Biochemical Assay Reagents
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Dextran T3 (Dextran 3; Dextran T3(MW 2400-3600)) is a neural tracer and intestinal permeability probe that can move anterogradely and retrogradely in neuronal axons by passive diffusion. Dextran T3 (MW 3,000) is able to permeate across the intestinal epithelial cell membrane in the presence of cholera toxin-induced cytoskeletal disturbance. Dextran T3 (MW 3,000) is used as a fluorescent marker to rapidly label developing neurons (such as Xenopus retinal ganglion cells) and to assess intestinal barrier function. It can be used to study axonal transport in neuroanatomy and permeability changes in intestinal pathophysiology. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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-
- HY-112624J
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Dextran 4; Dextran D4; Dextran T4(MW 3200-4800)
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Biochemical Assay Reagents
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|
Dextran 4,000 is a mucus rheology modifier. The dextran molecules in Dextran 4,000 can reduce the cross-link density of mucus through osmotic effects and hydrogen bond substitution, and reduce viscoelasticity and improve the mucociliary/cough clearance index by destroying the DNA-mucin network structure in mucus. Dextran 4,000 has the ability to improve the rheological properties and clearance ability of cystic fibrosis (CF) sputum, and can be used in the study of inhalation therapy or aerosol delivery of mucostatic respiratory diseases. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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-
- HY-112624D
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Dextran 60; Dextran D60; Dextran T60(MW 54000-66000)
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Biochemical Assay Reagents
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|
Dextran T60 MW 60,000 (Dextran 60; Dextran D60; Dextran T60 MW 54000-66000) is a polymer of anhydroglucose with the average molecular weight of 60,000. Dextran T60 MW 60,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
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- HY-116282I
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DSS (MW>500000); DXS (MW>500000)
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Biochemical Assay Reagents
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|
Dextran sulfate sodium salt (MW>500000) (DSS (MW>500000)) is a negatively charged sulfated polysaccharide. Dextran sulfate sodium salt has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate sodium salt can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .
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-
- HY-158082
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Tetramethyl rhodamine isothiocyanate glucan, MW 4000
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Biochemical Assay Reagents
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|
TRITC-dextran MW 4000 (Tetramethyl rhodamine isothiocyanate glucan, MW 4000) is a fluorescent dye, with the molecular weight of 4 kD. TRITC-dextran MW 4000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 4000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 4000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
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-
- HY-112624Q
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Dextran 800; Dextran D800; Dextran T800(MW 750000-850000)
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Biochemical Assay Reagents
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|
Dextran T800 MW 800,000 (Dextran 800; Dextran D800; Dextran T800 MW 750000-850000) is a polymer of anhydroglucose with the average molecular weight of 800,000. Dextran T800 MW 800,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
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-
- HY-112624T
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Dextran 7; Dextran D7; Dextran T7(MW 5600-8400)
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Biochemical Assay Reagents
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|
Dextran T7 (Dextran 7; Dextran D7) (MW 7,000) is a polymer of anhydroglucose with the average molecular weight of 7000. Dextran T7 (MW 7,000) exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
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-
- HY-112624N
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Dextran 200; Dextran D200; Dextran T200(MW 180000-220000)
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Biochemical Assay Reagents
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Dextran T200 (Dextran 200; Dextran D200) (MW 200,000) is a dehydrated glucose polymer with an average molecular weight of 200,000. Dextran T200 (MW 200,000) has excellent biodegradability and good biocompatibility, and can be used as a high-molecular-weight tracer and optical clearing agent .
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-
- HY-112624M
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Dextran 150; Dextran D150; Dextran T150(MW 130000-170000)
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Biochemical Assay Reagents
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|
Dextran T150 (Dextran 150; Dextran D150) (MW 150,000) is a dehydrated glucose polymer with an average molecular weight of 150,000. Dextran T150 (MW 150,000) has excellent biodegradability and good biocompatibility, and can be used as a fluorescent labeling tracer and a high-molecular cross-linking agent .
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- HY-112624U
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Dextran 20; Dextran D20; Dextran T20(MW 16000-24000)
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Biochemical Assay Reagents
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Dextran T20 (Dextran 20; Dextran D20) (MW 20,000) is a dehydrated glucose polymer with an average molecular weight of 20,000. Dextran T20 (MW 20,000) has excellent biodegradability and good biocompatibility, and can be used as a gene delivery vector, an immune adjuvant carrier, and a hemoglobin stabilizer .
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- HY-112624H
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Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)
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Biochemical Assay Reagents
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Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM2), and Isomaltotriose (IM3). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity .
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- HY-112624K
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Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)
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Biochemical Assay Reagents
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Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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-
- HY-112624O
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Dextran 100; Dextran D100; Dextran T100(MW 90000-110000)
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Biochemical Assay Reagents
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|
Dextran T100 (MW 100,000) (Dextran 100; Dextran D100) is a dehydrated glucose polymer with an average molecular weight of 100,000. Dextran T100 (MW 100,000) has an α-(1→6)-linked D-glucose backbone and α-(1→4)-, α-(1→3)- or α-(1→2)-linked D-glucose side chains, and it is synthesized by lactic acid bacteria or their enzymes. Dextran T100 (MW 100,000) possesses favorable biodegradability and biocompatibility, and it can be used in the fields of food, pharmaceuticals, cosmetics and research .
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- HY-112624E
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Dextran 0.8; Dextran D0.8; Dextran T0.8(MW 640-960)
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Biochemical Assay Reagents
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|
Dextran T0.8 (Dextran 0.8; Dextran T0.8(MW 640-960)) is a food additive with a porous network structure that exhibits strong hydration capacity and low browning activity. Dextran T0.8 (MW 800) can improve the coagulation of dairy products and is used as a prebiotic in baked goods. Dextran T0.8 (MW 800) is non-toxic to HeLa cells at a concentration of ~500 μg/mL and has a low relative browning rate in the Maillard reaction. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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- HY-W134328
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Dextran blue (MW 2000000)
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Biochemical Assay Reagents
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|
Blue dextran (Dextran blue) (MW 2000000) is a high-molecular-weight long-chain polymer of D-glucose. Blue dextran (MW 2000000) serves as an important model macromolecular drug and molecular weight estimation marker, and can be used as a standard for gel permeation chromatography. The release of Blue dextran (MW 2000000) from alginate microspheres is regulated by preparation conditions; its release rate in a pH 6.8 environment is significantly faster than that in pH 1.2, and it exhibits release characteristics close to zero-order kinetics under this condition .
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- HY-116282M
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Biochemical Assay Reagents
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Dextran sulfate, low sulfate (MW 40000), a biopolymer, is a sulfated polysaccharide. Dextran sulfate, low sulfate (MW 40000) has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .
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-
- HY-148139
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Biochemical Assay Reagents
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|
Cross-linked dextran G 75 is a Gel-filtration media. Cross-linked dextran G 75 also is a dextran-based matrix and used for Gel-filtration chromatography (Particle size range: 40-120 μm; Sphere protein separation range: 3K-80K Da; Polysaccharide separation range: 1K-50K Da) .
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-
- HY-W134327
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Diethylaminoethyl Dextran (MW 40000)
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Biochemical Assay Reagents
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DEAE-Dextran (MW 40000) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-107928B
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Biochemical Assay Reagents
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|
Iron-dextran (Fe 35-40% w/w) is an iron supplement (Fe 35-40% w/w). Iron-dextran can cause severe immune reactions, including anaphylactic shock. Iron-dextran can be used in studies of iron deficiency anemia .
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- HY-138560
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Biochemical Assay Reagents
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|
Cross-linked dextran G 50 is a gel filtration medium. Cross-linked dextran G 50 can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da) .
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-
- HY-158082B
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Tetramethyl rhodamine isothiocyanate glucan, MW 40000
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Biochemical Assay Reagents
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|
TRITC-dextran, MW 40000 (Tetramethyl rhodamine isothiocyanate glucan, MW 40000) is a fluorescent dye, with the molecular weight of 40 kD. TRITC-dextran MW 40000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 40000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 40000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
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-
- HY-158082A
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Tetramethyl rhodamine isothiocyanate glucan, MW 20000
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Biochemical Assay Reagents
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|
TRITC-dextran, MW 20000 (Tetramethyl rhodamine isothiocyanate glucan, MW 20000) is a fluorescent dye, with the molecular weight of 20 kD. TRITC-dextran MW 20000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 20000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 20000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
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-
- HY-W134328E
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Dextran blue (MW 70000)
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Biochemical Assay Reagents
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|
Blue dextran (MW 70000) (Dextran blue (MW 70000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin .
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- HY-172163
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Biochemical Assay Reagents
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|
FITC-dextran sulfate, 4kDa is a sodium dextran sulfate labeled with FITC, with an average molecular weight of 4 kDa .
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- HY-156045C
-
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Biochemical Assay Reagents
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|
Cross-linked dextran G 200 is a hydrophilic gel based on molecular size exclusion and targeted macromolecular separation. Cross-linked dextran G 200 works through the gel permeation mechanism, and the cross-linked structure forms a three-dimensional network with a specific pore size, achieving separation based on the molecular hydrodynamic volume. Cross-linked dextran G 200 can be used to adjust the osmotic solute distribution coefficient and the ability to maintain osmotic equilibrium, such as in gel filtration chromatography for purification and analysis of biomacromolecules such as proteins and nucleic acids . Cross-linked dextran G 200 can also be used as a gel filtration filler (particle size range: 40-120 μm; globular protein separation range: 5-600 kDa) .
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-
- HY-158082D
-
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Tetramethyl rhodamine isothiocyanate glucan, MW 150000
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Biochemical Assay Reagents
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|
TRITC-dextran, MW 150000 (Tetramethyl rhodamine isothiocyanate glucan, MW 150000) is a fluorescent dye, with the molecular weight of 150 kD. TRITC-dextran, MW 150000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 150000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 150000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
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-
- HY-W134328C
-
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Dextran blue (MW 20000)
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Biochemical Assay Reagents
|
|
Blue dextran (MW 20000) (Dextran blue (MW 20000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin .
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- HY-159067
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DEAE-Dextran, MW 500000 hydrochloride, from bacterial (Leuconostoc mesenteroides); Diethylaminoethyl-Dextran, MW 500000 hydrochloride
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Biochemical Assay Reagents
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|
DEAE-dextran, MW 500000 hydrochloride (DEAE-dextran, MW 500000 hydrochloride, from bacterial (Leuconostoc mesenteroides)) is a high-molecular-weight positively charged polymer that significantly enhances the uptake of viral RNA by tissue culture cells. When employed in the delivery system for "tumor immunity" RNA-splenocyte transfer, DEAE-dextran can markedly extend the lifespan of tumor-bearing animals, comparable to that of actively immunized animals. Furthermore, DEAE-dextran serves as a complexing agent for nucleic acids, forming composite particles with DNA/RNA for extensive applications in gene delivery. Additionally, DEAE-dextran can be utilized as a coating for liposomes .
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- HY-172163A
-
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Biochemical Assay Reagents
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FITC-dextran sulfate, 10kDa is a sodium dextran sulfate labeled with FITC, with an average molecular weight of 10 kDa .
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- HY-172163B
-
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Biochemical Assay Reagents
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|
FITC-dextran sulfate, 40kDa is a sodium dextran sulfate labeled with FITC, with an average molecular weight of 40 kDa .
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- HY-172163C
-
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Biochemical Assay Reagents
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FITC-dextran sulfate, 500kDa is a sodium dextran sulfate labeled with FITC, with an average molecular weight of 500 kDa .
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- HY-156045B
-
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Biochemical Assay Reagents
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|
Cross-linked dextran G 150 is a hydrophilic gel based on molecular size exclusion and targeted for the separation of macromolecules. Cross-linked dextran G 150 functions through the gel permeation mechanism, where the cross-linked structure forms a three-dimensional network with specific pore diameters, achieving separation based on the molecular volumetric flow. Cross-linked dextran G 150 can be used to regulate the distribution coefficient of permeating solutes and maintain the permeation balance, such as in gel filtration chromatography for the purification and analysis of biological macromolecules like proteins and nucleic acids. Cross-linked dextran G 150 can also be used as a gel filtration filler (particle size range: 40-120 μm; spherical protein separation range: 5-300 kDa) .
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- HY-158082E
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Tetramethyl rhodamine isothiocyanate glucan, MW 500000
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Biochemical Assay Reagents
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|
TRITC-dextran, MW 500000 (Tetramethyl rhodamine isothiocyanate glucan, MW 500000) is a fluorescent dye, with the molecular weight of 500 kD. TRITC-dextran, MW 500000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 500000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 500000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
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- HY-158082H
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Tetramethyl rhodamine isothiocyanate glucan, MW 2000000
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Biochemical Assay Reagents
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TRITC-dextran, MW 2000000 (Tetramethyl rhodamine isothiocyanate glucan, MW 2000000) is a fluorescent dye, with the molecular weight of 2000 kD. TRITC-dextran, MW 2000000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 2000000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 2000000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
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- HY-W134328A
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Dextran blue (MW 5000)
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Biochemical Assay Reagents
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Blue dextran (MW 5000) (Dextran blue (MW 5000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin .
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- HY-172164B
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Biochemical Assay Reagents
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|
FITC-lysine-dextran, 70kDa is a dextran with lysine coupling with a fluorescent group FITC (HY-66019). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-116282P
-
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Biochemical Assay Reagents
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Dextran sulfate, high sulfate (MW 5000) is a type of dextran sulfate with a high degree of sulfation. Dextran sulfate sodium can be used to induce ulcerative colitis models, and the greater the total number of sulfur atoms, the stronger the induced toxic effect. Dextran sulfate has certain antibacterial activity, and can form the ionic cross-linking core of nanoparticles together with chitosan, serving as a highly efficient dressing material to accelerate wound healing .
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- HY-116282J
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Biochemical Assay Reagents
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|
Dextran sulfate, low sulfate (MW 5000), a biopolymer, is a sulfated polysaccharide. Dextran sulfate, low sulfate (MW 5000) has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .
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- HY-148140B
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-
- HY-148140A
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-
- HY-148140C
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- HY-116282W
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DSS (MW 6500-10000); DXS (MW 6500-10000)
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Biochemical Assay Reagents
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|
Dextran sulfate sodium salt (DSS) (MW 6500-10000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 6500-10000) has antiviral activity against HIV-1 and HIV-2. Dextran sulfate sodium salt (MW 6500-10000) blocks the binding of virions to CD4 ⁺ T lymphocytes and inhibits syncytia formation. Dextran sulfate sodium salt (MW 6500-10000) also prevents experimental urolithiasis due to its cytoprotective actions. Moreover, because of its biocompatible and highly charged properties, Dextran sulfate sodium salt (MW 6500-10000) is a suitable choice for pharmaceutical systems .
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- HY-116282H
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DSS (MW 9000-20000); DXS (MW 9000-20000)
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Biochemical Assay Reagents
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Dextran sulfate sodium salt (DSS) (MW 9000-20000) is a polymer of dehydrated glucose with a molecular weight of approximately 9000-20000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 9000-20000) is a biocompatible and biodegradable biochemical reagent and can be used for pharmaceutical and biomedical applications .
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- HY-107928A
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Biochemical Assay Reagents
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Iron-Dextran is an injectable complex of iron and dextran, a complex carbohydrate. It is often used to improve iron deficiency anemia, a condition characterized by low levels of iron in the blood due to insufficient dietary intake or malabsorption. Iron-glucan works by providing a source of supplemental iron that the body can use to produce hemoglobin, the protein responsible for carrying oxygen in the blood. However, caution should be exercised when taking iron dextran because it may cause hypersensitivity reactions, including anaphylaxis, and may also increase the risk of infection or other adverse reactions. Therefore, it should only be administered under the supervision of a qualified healthcare provider in a clinical setting.
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- HY-W134328B
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Dextran blue (MW 10000)
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Biochemical Assay Reagents
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|
Blue dextran (Dextran blue) (MW 10000) is a 10 kDa osmotic dextran. Blue dextran (MW 10000) penetrates all sublayers of the pre-epithelial mucus gel layer in the rat distal colon and is taken up by the nuclei of surface cells in the rat distal colonic mucosa. Blue dextran (MW 10000) is not blocked by the pre-epithelial mucus gel layer of the rat distal colon, which acts as a diffusion barrier .
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- HY-141522A
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- HY-148139A
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- HY-W134328D
-
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Dextran blue (MW 40000)
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Biochemical Assay Reagents
|
|
Blue dextran (MW 40000) (Dextran blue (MW 4000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin .
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- HY-W134328I
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Dextran blue (MW 500000)
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Biochemical Assay Reagents
|
|
Blue dextran (MW 500000) (Dextran blue (MW 500000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin .
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- HY-W134328H
-
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Dextran blue (MW 110000)
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Biochemical Assay Reagents
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Blue dextran (MW 110000) (Dextran blue (MW 110000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin .
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- HY-172164
-
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Biochemical Assay Reagents
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FITC-lysine-dextran, 4kDa is a dextran with lysine coupling with a fluorescent group FITC (HY-66019). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-172166A
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Biochemical Assay Reagents
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TRITC-lysine-dextran, 10kDa is a dextran with lysine coupling with a fluorescent group TRITC (HY-D0791). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-138560A
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Biochemical Assay Reagents
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Cross-linked dextran G 50, medium is a gel filtration medium. Cross-linked dextran G 50, medium can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da). Cross-linked dextran G 50, medium are microspheres with an average particle size of D50 = 220-250 μm .
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- HY-138560B
-
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Biochemical Assay Reagents
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Cross-linked dextran G 50, fine is a gel filtration medium. Cross-linked dextran G 50, fine can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da). Cross-linked dextran G 50, fineThe average particle size is D50=110-130 μmof microspheres .
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- HY-172165A
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Biochemical Assay Reagents
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Lysine-dextran, 10kDa is a dextran with lysine coupling. Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-172165B
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Biochemical Assay Reagents
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Lysine-dextran, 20kDa is a dextran with lysine coupling. Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-172165
-
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Biochemical Assay Reagents
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Lysine-dextran, 4kDa is a dextran with lysine coupling. Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-172164A
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Biochemical Assay Reagents
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FITC-lysine-dextran, 10kDa is a dextran with lysine coupling with a fluorescent group FITC (HY-66019). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-172164C
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Biochemical Assay Reagents
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FITC-lysine-dextran, 500kDa is a dextran with lysine coupling with a fluorescent group FITC (HY-66019). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-172166
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Biochemical Assay Reagents
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TRITC-lysine-dextran, 4kDa is a dextran with lysine coupling with a fluorescent group TRITC (HY-D0791). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-172166B
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Biochemical Assay Reagents
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TRITC-lysine-dextran, 70kDa is a dextran with lysine coupling with a fluorescent group TRITC (HY-D0791). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-150352
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Biochemical Assay Reagents
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Dextran-COOH is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and other functional materials .
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- HY-158227
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DexMA (MW 200000)
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Biochemical Assay Reagents
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Dextran Methacryloyl (MW 200000) is a methacryloyl dextran that converts into cell matrix gels. Dextran Methacryloyl (MW 200000) formed gels that had no cytotoxic effects on fibroblasts, but cells adhered only inefficiently in long-term experiments . Dextran Methacryloyl (MW 200000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity. Application: cell culture, biological 3D printing, tissue engineering, etc.
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- HY-172387A
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- HY-172387
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- HY-172165C
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Biochemical Assay Reagents
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Lysine-dextran, 40kDa is a dextran with lysine coupling. Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-172165D
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Biochemical Assay Reagents
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Lysine-dextran, 70kDa is a dextran with lysine coupling. Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-172165E
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Biochemical Assay Reagents
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Lysine-dextran, 150kDa is a dextran with lysine coupling. Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-172165H
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Biochemical Assay Reagents
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Lysine-dextran, 500kDa is a dextran with lysine coupling. Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-172166C
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Biochemical Assay Reagents
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TRITC-lysine-dextran, 500kDa is a dextran with lysine coupling with a fluorescent group TRITC (HY-D0791). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .
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- HY-179081
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Biochemical Assay Reagents
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Phenyl-dextran 40 can be used to coat plastics or other related surfaces to impart more hydrophilic properties.
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- HY-183217C
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Biochemical Assay Reagents
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Dextran-Biotin (MW 100 kDa) is a functional material formed by covalently linking biotin to dextran molecules. Dextran-Biotin combines the biocompatibility of dextran with the high affinity of biotin for streptavidin, and is widely used in research fields such as biolabeling, detection, drug delivery, and neural tracking.
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- HY-183217E
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Biochemical Assay Reagents
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Dextran-Biotin (MW 500 kDa) is a functional material formed by covalently linking biotin to dextran molecules. Dextran-Biotin combines the biocompatibility of dextran with the high affinity of biotin for streptavidin, and is widely used in research fields such as biolabeling, detection, drug delivery, and neural tracking.
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- HY-183217D
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Biochemical Assay Reagents
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Dextran-Biotin (MW 250 kDa) is a functional material formed by covalently linking biotin to dextran molecules. Dextran-Biotin combines the biocompatibility of dextran with the high affinity of biotin for streptavidin, and is widely used in research fields such as biolabeling, detection, drug delivery, and neural tracking.
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- HY-183217B
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Biochemical Assay Reagents
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Dextran-Biotin (MW 70 kDa) is a functional material formed by covalently linking biotin to dextran molecules. Dextran-Biotin combines the biocompatibility of dextran with the high affinity of biotin for streptavidin, and is widely used in research fields such as biolabeling, detection, drug delivery, and neural tracking.
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- HY-183217
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Biochemical Assay Reagents
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Dextran-Biotin (MW 10 kDa) is a functional material formed by covalently linking biotin to dextran molecules. Dextran-Biotin combines the biocompatibility of dextran with the high affinity of biotin for streptavidin, and is widely used in research fields such as biolabeling, detection, drug delivery, and neural tracking.
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- HY-183217A
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Biochemical Assay Reagents
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Dextran-Biotin (MW 40 kDa) is a functional material formed by covalently linking biotin to dextran molecules. Dextran-Biotin combines the biocompatibility of dextran with the high affinity of biotin for streptavidin, and is widely used in research fields such as biolabeling, detection, drug delivery, and neural tracking.
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- HY-150352C
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Biochemical Assay Reagents
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Dextran-COOH (MW 100 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
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- HY-150352D
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Biochemical Assay Reagents
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Dextran-COOH (MW 250 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
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- HY-150352A
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Biochemical Assay Reagents
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Dextran-COOH (MW 10 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
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- HY-150352E
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Biochemical Assay Reagents
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Dextran-COOH (MW 500 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
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- HY-150352B
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Biochemical Assay Reagents
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Dextran-COOH (MW 70 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
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- HY-158227A
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DexMA (MW 500000)
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Biochemical Assay Reagents
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Dextran Methacryloyl (MW 500000) is a methacryloyl dextran that converts into cell matrix gels. Dextran Methacryloyl (MW 500000) formed gels that had no cytotoxic effects on fibroblasts, but cells adhered only inefficiently in long-term experiments . Dextran Methacryloyl (MW 500000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity. Application: cell culture, biological 3D printing, tissue engineering, etc.
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- HY-182663A
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Biochemical Assay Reagents
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Dextran-NH2 (MW 10 kDa) is a functional polysaccharide derivative that has been chemically modified to introduce amino (-NH2) active groups onto the molecular chain of natural dextran. Dextran-NH2 (MW 10 kDa) can be used as a drug delivery vehicle and a bioconjugation label.
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- HY-182663E
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Biochemical Assay Reagents
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Dextran-NH2 (MW 500 kDa) is a functional polysaccharide derivative that has been chemically modified to introduce amino (-NH2) active groups onto the molecular chain of natural dextran. Dextran-NH2 (MW 500 kDa) can be used as a drug delivery vehicle and a bioconjugation label.
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- HY-182663B
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Biochemical Assay Reagents
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Dextran-NH2 (MW 70 kDa) is a functional polysaccharide derivative that has been chemically modified to introduce amino (-NH2) active groups onto the molecular chain of natural dextran. Dextran-NH2 (MW 70 kDa) can be used as a drug delivery vehicle and a bioconjugation label.
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- HY-182663D
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Biochemical Assay Reagents
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Dextran-NH2 (MW 250 kDa) is a functional polysaccharide derivative that has been chemically modified to introduce amino (-NH2) active groups onto the molecular chain of natural dextran. Dextran-NH2 (MW 250 kDa) can be used as a drug delivery vehicle and a bioconjugation label.
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- HY-182663C
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Biochemical Assay Reagents
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Dextran-NH2 (MW 100 kDa) is a functional polysaccharide derivative that has been chemically modified to introduce amino (-NH2) active groups onto the molecular chain of natural dextran. Dextran-NH2 (MW 100 kDa) can be used as a drug delivery vehicle and a bioconjugation label.
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- HY-172388
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- HY-172388A
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- HY-141483
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- HY-156045
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Biochemical Assay Reagents
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Cross-linked dextran G 15 is a hydrophilic gel that can be used as a gel filter filler (Sphere protein separation range: >1500 Da; Polysaccharide separation range: >1500 Da) .
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- HY-156045A
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Biochemical Assay Reagents
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Cross-linked dextran G 10 is a weak cation exchanger and a hydrophilic gel that can be used as a gel filter filler (Sphere protein separation range: >700 Da; Polysaccharide separation range: >700 Da) .
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- HY-141522
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Biochemical Assay Reagents
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Cross-linked dextran G 100 is a gel filtration medium that can be used for protein purification (Sphere protein separation range: 4K-150K Da; Polysaccharide separation range: 1K-100K Da) .
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- HY-123115
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5-O-α-D-Glucopyranosyl-D-fructose
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Biochemical Assay Reagents
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Leucrose (5-O-α-D-Glucopyranosyl-D-fructose) is an orally active Sucrose (HY-B1779) isomer naturally found in pollen and honey. Leucrose promotes phosphorylation of JAK1 and STAT6, reduces pro-inflammatory mediators and cytokinesas (TNFα, and IL-1β), increases M2 macrophage polarization and suppresses DSS (HY-116282C)-induced colitis. Leucrose suppresses hepatic triglyceride accumulation, improves fasting blood glucose levels, and regulates hepatic lipogenesis and fatty acid β-oxidation in high-fat diet-induced obese mice. Leucrose is slowly hydrolyzed into glucose and fructose by α-glucosidase and acts as as a sugar substitute in diet .
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| Cat. No. |
Product Name |
Target |
Research Area |
Image |
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- HY-P990163
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Transmembrane Glycoprotein
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Inflammation/Immunology
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Anti-Mouse Siglec-H Antibody (440c) is a rat-derived IgG2b type antibody inhibitor, targeting to mouse Siglec-H. Anti-Mouse Siglec-H Antibody (440c) recognizes sialic acid-binding immunoglobulin (Ig)-like lectin family (Siglec-H) selectively expressing on plasmacytoid DCs and interferon–producing cells. Anti-Mouse Siglec-H Antibody (440c) can be used for the researches of inflammation and immunology, such as colitis .
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(5)
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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- HY-N0847
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-
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- HY-113227
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-
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- HY-N0648
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-
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- HY-N1388
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-
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- HY-N16021
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Structural Classification
Lipid
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Toll-like Receptor (TLR)
Cdc42-binding kinase
Galectin
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4A-MPLA ammonium is an orally active TLR4 agonist. 4A-MPLA ammonium induces TLR4 endocytosis dependent on Cdc42 and galectin-3, triggering TRIF-mediated signaling and sustained IFN-β production. 4A-MPLA ammonium promotes lipid droplet formation, upregulates interferon-stimulated genes and type I IFN signaling genes, downregulates lysosome/phagosome function genes, and modulates tolerogenic dendritic cell function. 4A-MPLA ammonium can be used for the research of colitis .
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-
-
- HY-N0278
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Pulsatilla camphor; Anemonine; trans-Anemonin
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Natural Products
Ranunculaceae
Clematis crassifolia Benth.
Plants
Source Classification
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PKC
NO Synthase
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Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases .
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-
-
- HY-N0278A
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(Rac)-Pulsatilla camphor; (Rac)-Anemonine
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Natural Products
Ranunculaceae
Clematis crassifolia Benth.
Plants
Source Classification
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PKC
NO Synthase
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(Rac)-Anemonin ((Rac)-Pulsatilla camphor) is the diastereoisomer of Anemonin (HY-N0278). Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases .
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-
-
- HY-N2478
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-
-
- HY-N1388R
-
-
-
- HY-N2478R
-
-
-
- HY-N0648R
-
-
-
- HY-N0847R
-
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Structural Classification
Other Monoterpenes
other families
Terpenoids
Plants
Source Classification
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Reference Standards
NF-κB
PI3K
Akt
TGF-beta/Smad
|
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Micheliolide is a sesquiterpene lactone with anti-cancer and anti-inflammatory effects, which is derived from Michelia compressa and Michelia champaca. Micheliolide can attenuate high glucose-stimulated NF-κB activation, IκBα degradation, and the expression of MCP-1, TGF-β1, and FN in mouse mesangial cells. Micheliolide inhibits LPS (HY-D1056)-induced activation of NF-κB and PI3K/Akt/p70S6K pathways to play an anti-inflammatory role. Micheliolide inhibits dextran sodium sulphate (DSS) (HY-116282)-induced inflammatory intestinal disease, colitis-associated cancer and rheumatic arthritis .
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-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-164416
-
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DBCO
|
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DBCO-Dextran sulfate (MW 40000) can be used to construct DS-EXOs in cells via click chemistry, that can be used for the research of rheumatoid arthritis (RA) .
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-
- HY-164072
-
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DBCO
|
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DBCO-Dextran is a dibenzocyclooctyne-modified dextran with excellent click chemistry activity and biocompatibility, which can be used in cancer immunotherapy and bioimaging research .
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| Cat. No. |
Product Name |
|
Classification |
-
- HY-112624
-
Dextran
2 Publications Verification
Dextran 40
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Fillers
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Dextran (Dextran 40) has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander.
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-
- HY-112624B
-
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Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)
|
|
Polymers
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Dextran 70,000 is a high molecular weight polysaccharide formed by glucose linked by α-(1→6) glycosidic bonds. Dextran 70,000 can expand blood volume through colloidal osmotic pressure effect and inhibit cell adhesion and platelet aggregation through steric hindrance. At the same time, Dextran 70,000 can be used as a drug carrier to achieve targeted delivery through endocytosis. Dextran 70,000 is biologically inert and has low immunogenicity. It can be used for clinical blood volume expansion, anti-thrombotic research, and evaluation of vascular permeability in in vitro experiments. It can also be combined with fluorescent dyes for cell tracking and drug delivery research. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance.
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