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Isoforms Recommended:	EP

Results for "

EP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (4) Acyltransferase (5) Akt (1) Amyloid-β (1) Androgen Receptor (1) Antibiotic (1) Apoptosis (7) Aurora Kinase (1) Bacterial (6) Bcl-2 Family (2) Beta-lactamase (1) Biochemical Assay Reagents (3) c-Myc (2) Calcium Channel (1) Carbonic Anhydrase (1) Caspase (4) CDK (2) COX (1) CTLA-4 (1) Cytochrome P450 (2) Dopamine Receptor (1) Drug Derivative (6) Drug Intermediate (18) Drug Metabolite (24) E3 Ligase Ligand-Linker Conjugates (1) EGFR (1) Endogenous Metabolite (9) Environmental Pollutants (2) Epigenetic Reader Domain (16) Estrogen Receptor/ERR (1) Exosomes (1) Factor Xa (2) Factor XI (1) Fungal (4) GHR (1) GHSR (2) GnRH Receptor (2) HDAC (1) Histamine Receptor (3) Histone Acetyltransferase (26) Histone Demethylase (1) HIV (1) HIV Protease (1) HMG-CoA Reductase (HMGCR) (1) Interleukin Related (5) Isotope-Labeled Compounds (26) JAK (1) LAG-3 (1) Ligands for Target Protein for PROTAC (2) Liposome (1) Lipoxygenase (2) mAChR (3) Mas-related G-protein-coupled Receptor (MRGPR) (2) METTL3 (2) Mitochondrial Metabolism (1) Mitophagy (2) MMP (2) MOFs (1) nAChR (1) NF-κB (2) Opioid Receptor (1) P-glycoprotein (1) Parasite (1) PARP (1) PD-1/PD-L1 (4) PERK (1) PGE synthase (1) Phosphatase (1) Phosphodiesterase (PDE) (1) PI3K (1) PINK1/Parkin (1) PKA (1) Potassium Channel (1) PPAR (2) Prostaglandin Receptor (147) PROTACs (3) Quinone Reductase (1) Raf (1) Ras (1) Reference Standards (29) RSV (1) Ser/Thr Protease (1) Sirtuin (1) Small Interfering RNA (siRNA) (14) STAT (2) TGF-beta/Smad (2) Thrombin (1) Thrombopoietin Receptor (1) Transmembrane Glycoprotein (5) VD/VDR (2) Wnt (2) β-catenin (1)
By Research Areas:	Cancer (88) Cardiovascular Disease (35) Endocrinology (64) Infection (10) Inflammation/Immunology (82) Metabolic Disease (25) Neurological Disease (35)
Oligonucleotides:	Rat Pre-designed siRNA Sets (2) Cationic Lipids (1) Mouse Pre-designed siRNA Sets (3) Human Pre-designed siRNA Sets (9) siRNAs (14)

333

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-152943

MTK458 4 Publications Verification EP-0035985	PINK1/Parkin Mitophagy Mitochondrial Metabolism	Neurological Disease Cancer
MTK458 is an orally active brain penetrant PINK1 activator. MTK458 binds to PINK1 and stabilizes an active heterocomplex, thereby increasing mitophagy. MTK458 can be used for research on Parkinson's disease .

HY-14383

Vosilasarm 5+ Cited Publications RAD140; EP0062	Androgen Receptor	Neurological Disease Endocrinology Cancer
Vosilasarm (RAD140) is a potent, orally active, nonsteroidal selective androgen receptor modulator (SARM) with a K_i of 7 nM. Vosilasarm shows good selectivity over other steroid hormone nuclear receptors .

HY-14820A

Macimorelin acetate EP-1572 acetate; AEZS-130 acetate	GHSR	Neurological Disease Endocrinology Cancer
Macimorelin (EP-1572) acetate, a GH secretagogue, is an orally active GHSR agonist. Macimorelin acetate stimulates GH release. Macimorelin acetate can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS) .

HY-136938

NEO2734 4 Publications Verification EP31670	Epigenetic Reader Domain Histone Acetyltransferase	Cancer
NEO2734 (EP31670) is an orally active dual p300/CBP and BET bromodomain selective inhibitor, with IC₅₀ values of <30 nM for both p300/CBP and BET bromodomains . NEO2734 is active in SPOP mutant and wild-type prostate cancer .

HY-136645

EP4 receptor antagonist 2	Prostaglandin Receptor	Cancer
EP4 receptor antagonist 2 (Compound 8) is a tricyclic spiro-based *EP₄* receptor antagonist with microsomal stability .

HY-145794

ZA3-Ep10	Liposome	Cancer
ZA3-Ep10 is a zwitterionic lipid used in lipid nanoparticles formulation for in vivo RNA delivery.

HY-133123

EP4 receptor antagonist 1 2 Publications Verification	Prostaglandin Receptor	Inflammation/Immunology Cancer
EP4 receptor antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist for cancer immunotherapy. EP4 receptor antagonist 1 inhibits human and mouse EP4 receptor with IC₅₀s of 6.1 nM and 16.2 nM, respectively. IC₅₀s >10 μM for human EP1, EP2,and EP3 receptors .

HY-176293

EP2 receptor antagonist-3	Prostaglandin Receptor Amyloid-β	Neurological Disease
EP2 receptor antagonist-3 is a selective EP2 receptor antagonist (IC₅₀: 8 nM in hEP2 SPA assay, 50 nM in hEP2 cAMP assay). EP2 receptor antagonist-3 increases the macrophage-mediated clearance of Amyloid-β plaques. EP2 receptor antagonist-3 can be used for the study of alzheimer’s diseases .

HY-156613

Frunexian EP-7041	Factor XI	Infection
Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, targeting to factor XIa. Frunexian exhibits antithrombotic activity, with no bleeding liability in rat mesenteric arterial puncture model. Frunexian can be used in extracorporeal membrane oxygenation (ECMO) research .

HY-101172

RS 23597-190 EP-A-501322	5-HT Receptor	Cardiovascular Disease
RS 23597-190 (EP-A-501322) is a high affinity and selective 5-HT4 receptor antagonist. RS 23597-190 inhibits Serotonin (HY-B1473A)-induced tachycardia. RS 23597-190 significantly inhibits superoxide production in high glucose .

HY-153935

EP4-IN-1	Prostaglandin Receptor	Inflammation/Immunology Cancer
EP4-IN-1 is a potent prostanoid EP4 receptor inhibitor. EP4-IN-1 is extracted from patent WO2023025270 (example 1), and exhibits prospect in tumor immunity and anti-inflammatory analgesia research .

HY-168878

EP652	METTL3	Cancer
EP652 is a METTL3 inhibitor and antitumor agent with IC₅₀ values of 2 nM, <10 nM, and 37 nM in SPA, intracellular, and ATPlite assays, respectively. EP652 exhibits high selectivity against 40 other methyltransferases and FTO, and possesses favorable pharmacokinetic parameters. EP652 reduces intracellular N ⁶-methyladenosine (m ⁶A) levels in mRNA. EP652 inhibits tumor growth and progression of both hematologic malignancies and solid tumors. EP652 can be used for the research of acute myeloid leukemia, ovarian cancer, non-small cell lung cancer, and hypopharyngeal squamous cell carcinoma .

HY-153129

EP2 receptor antagonist-2	Prostaglandin Receptor	Endocrinology
EP2 receptor antagonist-2 (CID891729) is an antagonist of EP2 receptor. EP2 receptor antagonist-2 inhibits the EP2 receptor activation induced by PGE2. EP2 receptor antagonist-2 also suppresses lactate dehydrogenase (LDH) release induced by N-methyl-D-aspartate (NMDA) .

HY-145684

EP2 receptor antagonist-1	Prostaglandin Receptor	Inflammation/Immunology
EP2 receptor antagonist-1 (compound 1) is a potent, reversible, and agonist dependent allosteric prostaglandin EP2 receptor antagonist. EP2 receptor antagonist-1 shows anti-inflammatory effects .

HY-147226

EP3 antagonist 3	Prostaglandin Receptor	Neurological Disease Endocrinology
EP3 antagonist 3 (compound 2) is an orally active, potent and selective *EP3* antagonist, with a pK_i of 8.3. EP3 antagonist 3 shows excellent pharmacokinetic properties. EP3 antagonist 3 can be used for overactive bladder (OAB) research .

HY-118609

EP4 receptor agonist 2	Prostaglandin Receptor	Inflammation/Immunology
EP4 receptor agonist 2 (compound 31) a potent EP4 receptor agonist with an EC₅₀ value of 0.8 nM; K_i values of >100000, 38000, 3.1 nM for EP2, EP3, EP4 respectively .

HY-RS04405

EP300 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
EP300 Human Pre-designed siRNA Set A contains three designed siRNAs for EP300 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

EP300 Human Pre-designed siRNA Set A EP300 Human Pre-designed siRNA Set A

HY-14820

Macimorelin EP-1572; AEZS-130	GHSR	Endocrinology Cancer
Macimorelin (EP-1572), a GH secretagogue, is an orally active GHSR agonist. Macimorelin stimulates GH release. Macimorelin can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS) .

HY-169859

EP4 receptor antagonist 7	Prostaglandin Receptor Interleukin Related	Inflammation/Immunology Cancer
EP4 receptor antagonist 7 (Compound 14) is an antagonist of the prostaglandin E2 (PGE2) receptor subtype EP4 with an IC₅₀ value of 1.1 nM. EP4 receptor antagonist 7 inhibits PGE2-induced β-arrestin recruitment in HEK293 cells with an IC₅₀ value of 0.9 nM. EP4 receptor antagonist 7 decreases PGE2-induced expression of mRNA encoding IL-4, macrophage mannose receptor 1 (Mrc1), chitinase-like protein 3 (Chil3), chemokine (C-X-C) motif ligand 1 (Cxcl1), triggering receptor expressed on myeloid cells 2 (Trem2), and arginase-1 (Arg1), in RAW 264.7 macrophages. EP4 receptor antagonist 7 combined with an anti-PD-1 antibody inhibits tumor growth and increases infiltration of CD ⁸⁺ T cells into tumors in a CT26 murine colon cancer model .

HY-P4144

Onvitrelin ucalontide Phor18-LHRH (338613); EP-100	GnRH Receptor	Endocrinology Cancer
Onvitrelin ucalontide ([Phor18-LHRH (338613)]) is an analogue of luteinizing hormone releasing hormone (LHRH) with antineoplastic activity. Onvitrelin ucalontide is a peptide with sequences of KFAKFAKKFAKFAKKFAKQHWSYGLRPG. Onvitrelin ucalontide effectively inhibits breast cancer, ovarian cancer and prostate cancer xenografts in mouse model .

HY-P2696

EP 80317	Transmembrane Glycoprotein	Cardiovascular Disease
EP 80317 is a selective CD36 ligand. EP 80317 protects the heart against damage and dysfunction elicited by myocardial ischaemia and reperfusion (MI/R), along with a transient reduction in peripheral lipolysis. EP 80317 can be used for the study of cardiovascular disease .

HY-P5702

EP3	Bacterial Apoptosis Fungal	Infection
EP3 is an antimicrobial peptide. EP3 has antibacterial and antifungal activities. EP3 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 12.85 μg/mL. EP3 also shows antitumor activity against cancer cells, and induces cell apoptosis .

HY-160260

EP300/CBP-IN-1	Epigenetic Reader Domain Histone Acetyltransferase	Cancer
EP300/CBP-IN-1 (compound 172) is a potent *EP300/CBP* inhibitor with IC₅₀s of 2.3 nM and 2.1 nM for CBP BRD and EP300 BRD, respectively. EP300/CBP-IN-1 has the inhibitory effect on the proliferation of prostate cancer CWR22RV1 cells .

HY-173003

EP-3945	Mas-related G-protein-coupled Receptor (MRGPR)	Inflammation/Immunology
EP-3945 is a potent agonist of Mas-related G protein-coupled receptor (MRGPR), more effective than the MRGPRD small molecule agonist β-Alanine (HY-N0230). MRGPR plays a crucial role in inflammatory pruritus and pain sensation. Additionally, MRGPR binds to Gq (MRGPRX2, MRGPRX4, MRGPRX1 couple with Gq; MRGPRX2, MRGPRD couple with Gi), with EP-3945 measured EC₅₀ for Gq being 211.6 nM .

HY-128362

Ep300/CREBBP-IN-8	Histone Acetyltransferase	Cancer
Ep300/CREBBP-IN-8 (Example 37) is a potent and orally active *Ep300* and CREBBP inhibitor with IC₅₀s of 0.014 and 0.018 μM, respectively. Ep300/CREBBP-IN-8 can be used for the research of cancer .

HY-178465

EP4 receptor antagonist 8	Prostaglandin Receptor Interleukin Related	Neurological Disease Inflammation/Immunology
EP4 receptor antagonist 8 is an orally active *EP4* antagonist (human EP4 IC₅₀ = 6.40 nM). EP4 receptor antagonist 8 significantly reduced paw and joint swelling, inflammatory cell infiltration, cartilage damage, pannus formation, and joint bone erosion in arthritis (AIA) mice in a dose-dependent manner. EP4 receptor antagonist 8 can be used for the study of inflammatory pain .

HY-105173

Teverelix EP 24332	GnRH Receptor Histamine Receptor	Endocrinology Cancer
Teverelix (EP 24332) is a GnRH antagonist. Teverelix binds competitively and reversibly to GnRH receptors, thereby suppressing the release of LH and FSH. Teverelix can be used in the research of prostatic hyperplasia, endometriosis, and prostate cancer .

HY-10397

EP1013 F1013	Caspase	Metabolic Disease
EP1013 (F1013) is a broad-spectrum caspase selective inhibitor, used in the research of type 1 diabetes .

HY-159843

Glasmacinal EP395	RSV	Inflammation/Immunology
Glasmacinal is a non-antibacterial macrolide agent with anti-inflammatory activity .

HY-19305

EP-51216	GHR	Inflammation/Immunology
EP-51216 is a growth hormone agonist peptide. EP-51216 increases food intake. EP-51216 can be used in the research of eating disorders .

HY-118220

EP 171	Thrombin	Cardiovascular Disease
EP 171 is a TP receptor agonist and human platelet activator. EP 171 can induce constriction of guinea pig trachea, and the constriction can be inhibited by the TP receptor antagonist EP 092. EP 171 binds to TP receptors on intact human platelets with an IC₅₀ of 2.9 nM .

HY-P5703

EP5-1	Bacterial Apoptosis Fungal	Infection
EP5-1 is an antimicrobial peptide. EP5-1 has antibacterial and antifungal activities. EP5-1 also shows antitumor activity against cancer cells, and induces cell apoptosis. EP5-1 has antiviral activity against pseudorabies virus (PRV) .

HY-149513

EP12	c-Myc Apoptosis	Cancer
EP12 is a c-Myc inhibitor. EP12 is a c-Myc G4 stabilizer. EP12 induces apoptosis and DNA damage in multiple myeloma cells. EP12 disrupts the nuclear translocation of P65/P50 by interfering with the NF-κB signaling pathway. EP12 inhibits multiple myeloma growth .

HY-P5701

EP2	Bacterial Fungal	Infection
EP2 is an antimicrobial peptide. EP2 has antibacterial and antifungal activities. EP2 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 11.4 μg/mL .

HY-120495

EP6	Lipoxygenase	Cancer
EP6 is a potent 5-Lipoxygenase (5-LO) inhibitor. EP6 inhibits the cell viability of tumor cells without mutagenic activity. EP6 can be used in research of cancer .

HY-159101

EP26	EGFR PD-1/PD-L1	Cancer
EP26 is a potent and orally active EGFR and PD-L1 inhibitor with IC₅₀ values of 48.6 nM, 1.77 µM, respectively. EP26 decreased the protein expression of p-EGFR. EP26 induces cell cycle arrest at G0/G1 phase. EP26 has the potential for the research of glioblastoma .

HY-101695

EP1-antagonist-1	Prostaglandin Receptor	Neurological Disease Endocrinology
EP1-antagonist-1 (Compound 27) is an *EP1* antagonist with a pK_i (FLIPR) of 9.31 and a pIC₅₀ (binding) of 9.88. EP1-antagonist-1 can be used for the study of PGE2-mediated pain .

HY-160261S

EP300/CBP-IN-2	Epigenetic Reader Domain	Cancer
EP300/CBP-IN-2 is a potent *EP300/CBP* inhibitor that has good activity in vivo. EP300/CBP-IN-2 can be used for the research of cancer .

HY-152943A

(Rac)-MTK458 (Rac)-EP-0035985	Mitophagy	Cancer
(Rac)-MTK458 (compound 16) is an activator of mitophagy. EP-0035985 is the isomer of EP-0035985 .

HY-150536

EP39	HIV HIV Protease	Infection
EP39 is a potent HIV-1 maturation inhibitor. EP39 interacts with the SP1 domain of Gag. EP39 decreases the dynamics of CA-SP1 junction, by binding to the QVT motif of the SP1 domain, and perturbs the natural coil-helix equilibrium on both sides of the SP1 domain by stabilizing the transient alpha helical structure. EP39 acts by arresting maturation of HIV-1 thereby blocking its infectivity .

HY-128367

Ep300/CREBBP-IN-4	Histone Acetyltransferase	Cancer
Ep300/CREBBP-IN-4 (Example 56) is a potent *Ep300* and CREBBP inhibitor with IC₅₀s of 0.024 and 0.064 μM, respectively. Ep300/CREBBP-IN-4 can be used for the research of cancer .

HY-128364

Ep300/CREBBP-IN-3	Histone Acetyltransferase	Cancer
Ep300/CREBBP-IN-3 (Example 61) is a potent *Ep300* and CREBBP inhibitor with IC₅₀s of 0.056 and 0.095 μM, respectively. Ep300/CREBBP-IN-3 can be used for the research of cancer .

HY-128363

Ep300/CREBBP-IN-2	Histone Acetyltransferase	Cancer
Ep300/CREBBP-IN-2 (Example 73) is a potent and orally active *Ep300* and CREBBP inhibitor with IC₅₀s of 0.052 and 0.148 μM, respectively. Ep300/CREBBP-IN-2 can be used for the research of cancer .

HY-P3417

Amp1EP9	Bacterial	Infection
Amp1EP9 is an antimicrobial peptide. Amp1EP9 is a powerful tool for developing potent and nontoxic antimicrobial agents. Amp1EP9 has the potential for the research of multidrug-resistant bacterial infections .

HY-177544

EP1 receptor antagonist-1	Prostaglandin Receptor	Endocrinology
EP1 receptor antagonist-1 (Compound Example 5a freebase) is an EP1 prostaglandin receptor antagonist. EP1 receptor antagonist-1 is promising for research of urinary system-related diseases .

HY-157496

EP3 antagonist 7	Prostaglandin Receptor	Others
EP3 antagonist 7 (Compound II) is an EP3 receptor antagonist. EP3 antagonist 7 can be used in the study of itching, pain, dysuria or stress disorders .

HY-W153917

Diatrizoic acid EP impurity A	Biochemical Assay Reagents
Diatrizoic acid EP impurity A is an organic compound with potential effects on biological systems and specific pharmacological activities. Diatrizoic acid EP impurity A can be used as a contrast agent in imaging examinations to enhance the clarity of images such as X-rays and CT scans. Diatrizoic acid EP impurity A has also been studied for the separation and analysis of compounds.

HY-131664

EP3 antagonist 2	Prostaglandin Receptor	Others
EP3 antagonist 2 (Compound Exp 1) is a potent and selective *EP3* receptor antagonist. EP3 antagonist 2 has a strong binding affinity for the human *EP3* receptor (K_i: 3.3 nM) and significant antagonistic activity (IC₅₀: 30.8 nM, determined by cellular cAMP levels) .

HY-153256

EP3 antagonist 4	Prostaglandin Receptor	Metabolic Disease
EP3 antagonist 4 (Compound 28) is an *EP3* antagonist, with a K_i value of 2 nM for hEP. EP3 antagonist 4 shows low in vivo clearance, high oral AUC, and good bioavailability in the rat full PK studies. EP3 antagonist 4 can be used for research of beta cell dysfunction in diabetes .

HY-157494

EP3 antagonist 5	Prostaglandin Receptor	Others
EP3 antagonist 5 (Compound 22) is an *EP3* receptor antagonist with an IC₅₀ value of 67 nM .

Cat. No.	Product Name

HY-L066

FDA Approved & Pharmacopeial Drug Library

3,729 compounds

New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or retasking) offers various advantages over developing an entirely new drug for a given indication. First, the risk of failure is lower. Second, the time frame for drug development can be reduced. Third, less investment is needed. Approved drugs and pharmacopoeia collected compounds have identified bioactivities, good pharmacokinetic characteristics and safety which are suitable for drug repurposing.

MCE owns a unique collection of 3,729 compounds from approved institutions such as FDA, EMA, NMPA, PMDA, etc. or pharmacopoeia such as USP, BP, JP, etc. These compounds have well-characterized bioactivities, safety and bioavailability properties. MCE FDA Approved & Pharmacopeial Drug Library is a good tool for drug repurposing which could dramatically accelerate drug development.

Cat. No.	Product Name	Target	Research Area

HY-P4457

Leuprolide Acetate EP Impurity D	Peptides	Cancer
Leuprolide Acetate EP Impurity D is the impurity of Leuprolide (Leuprorelin) .

HY-P4144

Onvitrelin ucalontide Phor18-LHRH (338613); EP-100	GnRH Receptor	Endocrinology Cancer
Onvitrelin ucalontide ([Phor18-LHRH (338613)]) is an analogue of luteinizing hormone releasing hormone (LHRH) with antineoplastic activity. Onvitrelin ucalontide is a peptide with sequences of KFAKFAKKFAKFAKKFAKQHWSYGLRPG. Onvitrelin ucalontide effectively inhibits breast cancer, ovarian cancer and prostate cancer xenografts in mouse model .

HY-P2696

EP 80317	Transmembrane Glycoprotein	Cardiovascular Disease
EP 80317 is a selective CD36 ligand. EP 80317 protects the heart against damage and dysfunction elicited by myocardial ischaemia and reperfusion (MI/R), along with a transient reduction in peripheral lipolysis. EP 80317 can be used for the study of cardiovascular disease .

HY-P5702

EP3	Bacterial Apoptosis Fungal	Infection
EP3 is an antimicrobial peptide. EP3 has antibacterial and antifungal activities. EP3 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 12.85 μg/mL. EP3 also shows antitumor activity against cancer cells, and induces cell apoptosis .

HY-105173

Teverelix EP 24332	GnRH Receptor Histamine Receptor	Endocrinology Cancer
Teverelix (EP 24332) is a GnRH antagonist. Teverelix binds competitively and reversibly to GnRH receptors, thereby suppressing the release of LH and FSH. Teverelix can be used in the research of prostatic hyperplasia, endometriosis, and prostate cancer .

HY-P5703

EP5-1	Bacterial Apoptosis Fungal	Infection
EP5-1 is an antimicrobial peptide. EP5-1 has antibacterial and antifungal activities. EP5-1 also shows antitumor activity against cancer cells, and induces cell apoptosis. EP5-1 has antiviral activity against pseudorabies virus (PRV) .

HY-P5701

EP2	Bacterial Fungal	Infection
EP2 is an antimicrobial peptide. EP2 has antibacterial and antifungal activities. EP2 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 11.4 μg/mL .

HY-P3417

Amp1EP9	Bacterial	Infection
Amp1EP9 is an antimicrobial peptide. Amp1EP9 is a powerful tool for developing potent and nontoxic antimicrobial agents. Amp1EP9 has the potential for the research of multidrug-resistant bacterial infections .

HY-P4454

Goserelin EP Impurity E	Drug Derivative	Cancer
Goserelin EP Impurity E is the impurity of Goserelin (HY-13673) .

HY-P3517

β-Endorphin (6-31), human β-EP (6-31), human	Opioid Receptor	Neurological Disease Endocrinology
β-Endorphin, an endogenous opioid neuropeptide, is an opioid receptor agonist. β-Endorphin binds preferentially to μ-opioid receptors and is produced in certain neurons of the central and peripheral nervous system and is one of three endorphins produced in humans. β-Endorphin can be used to reduce stress and maintain homeostasis in the body and is involved in neurological pain perception regulation .

HY-P2696A

EP 80317 acetate	Transmembrane Glycoprotein	Cardiovascular Disease
EP 80317 acetate is a selective CD36 ligand. EP 80317 acetate protects the heart against damage and dysfunction elicited by myocardial ischaemia and reperfusion (MI/R), along with a transient reduction in peripheral lipolysis. EP 80317 acetate can be used for the study of cardiovascular disease .

HY-P11797

EP9	Transmembrane Glycoprotein	Cardiovascular Disease
EP9 is a 7-amino acid peptide targeting CD63. EP9 binds specifically to the extracellular region of CD63, including a groove in the large extracellular loop (EC2) or the extracellular end of CD63’s central cavity, triggering endocytosis of decorated nanoemulsions/liposomes into cells. EP9 promotes cellular uptake of decorated nanoemulsions/liposomes into activated cardiac fibroblasts and epicardial stromal cells via caveolae and/or clathrin-coated pits. EP9 can be used for the research of myocardial infarction, cardiac fibrosis .

Cat. No.	Product Name	Target	Research Area	Image

HY-P991631

Human IgG1 (L234F/L235E/P331S) kappa, Isotype Control	Inhibitory Antibodies	Inflammation/Immunology
Human IgG1 (L234F/L235E/P331S) kappa, Isotype Control, a human-derived antibody, is an isotype control for human IgG1 (L234F/L235E/P331S)κ antibody.

HY-P991646

ING-1 heMab	Transmembrane Glycoprotein	Cancer
ING-1 (heMab) is a high-affinity humanized monoclonal antibody against epithelial cell adhesion molecule (Ep-CAM). ING-1 is a transmembrane glycoprotein mediating Ca ²⁺. ING-1 binds to Ep-CAM on tumor cells and exhibits potent in vitro activity, targeting and inhibiting tumor growth and metastasis in mouse cancer models. ING-1 is useful in the research of breast, colorectal, and lung cancers, among other cancers .

HY-P990862

Anti-CD326/EpCAM Antibody (Ber-EP4)	Transmembrane Glycoprotein	Cancer
Anti-CD326/EpCAM Antibody (Ber-EP4) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CD326/EpCAM. Anti-CD326/EpCAM Antibody (Ber-EP4) reacts with human CD326 also known as EpCAM (Epithelial Cell Adhesion Molecule). Anti-CD326/EpCAM Antibody (Ber-EP4) is useful to distinguish between cells of mesothelial and epithelial origin. Anti-CD326/EpCAM Antibody (Ber-EP4) can be used for the detections of immunohistochemistry, immunofluorescence and flow cytometry in cancer, such as colon cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0131

Prostaglandin E1 20+ Cited Publications Alprostadil; PGE1	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification	Prostaglandin Receptor Endogenous Metabolite
Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with K_is of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, *EP4, EP2, IP and EP1*, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases .

HY-N6070

Ricinoleic acid (purity≥85%)	Structural Classification Classification of Application Fields Ricinus communis L. Ketones, Aldehydes, Acids Other Diseases Euphorbiaceae Plants Disease Research Fields Source Classification	Environmental Pollutants Prostaglandin Receptor
Ricinoleic acid (purity≥85%), a hydroxy fatty acid, is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings. Ricinoleic acid is the main active ingredient of Castor oil (HY-107799). Ricinoleic acid is the agonist for prostaglandin EP3 receptor (EP3 receptor) (EC₅₀ in MEG-01 is 0.5 μM), that causes laxative effects and uterine contraction. Ricinoleic acid exhibits antianxiety-like, anti-inflammatory and pro-inflammatory properties .

HY-112023

Lumisterol 3 (purity>90%) 9β,10α-Cholesta-5,7-dien-3β-ol; Cholecalciferol EP Impurity C	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite
Lumisterol 3 (>90%) (9β,10α-Cholesta-5,7-dien-3β-ol) is a normal human secosterooid metabolite from the class of vitamin D3 photoisomer derivatives. Lumisterol 3 (>90%) is used in the preparation of vitamin D .

HY-125847

Salvianolic acid F 1 Publications Verification	Stilbenes Classification of Application Fields Labiatae Samanea saman (Jacq.) Merr. Phenols Polyphenols Plants Disease Research Fields Source Classification Cancer	Ras PI3K Akt Caspase Apoptosis Bcl-2 Family NF-κB MMP
Salvianolic acid F is a KRAS inhibitor, especially for KRAS G12D. Salvianolic acid F inhibits NF-kB, MMP-9, and NO simultaneously. Salvianolic acid F inhibits cancer cell growth, invasion, and migration and induces apoptosis via the EP300/PI3K/AKT pathway in vitro. Salvianolic acid F inhibits the growth of KRAS-dependent lung cancer cells via the PI3K/AKT signaling pathway in vivo. Salvianolic acid F can be used in the research of various cancers, including KRAS G12D-driven non-small cell lung cancer (NSCLC) and ovarian cancer .

HY-113205

15-keto-Prostaglandin E2 15-keto-PGE2	Structural Classification Ketones, Aldehydes, Acids Marine algae Marine natural products Source Classification	Endogenous Metabolite Prostaglandin Receptor STAT PPAR Fungal Drug Metabolite
15-keto-Prostaglandin E2 (15-keto-PGE2) is an endogenous PGE₂ metabolite. 15-keto-Prostaglandin E2 inhibits STAT3 activation by binding to the Cys259 residue of STAT3. 15-keto-Prostaglandin E2 binds to and stabilizes *EP2* and *EP4* receptors. 15-keto-Prostaglandin E2 inhibits the growth and progression of breast cancer cells. 15-keto-Prostaglandin E2 activates PPAR-γ and promotes fungal growth. 15-keto-Prostaglandin E2 disrupts glomerular vascularization during zebrafish development and reduces the surface area of the glomerular filtration barrier .

HY-P5702

EP3	Animals Ketones, Aldehydes, Acids Source Classification	Bacterial Apoptosis Fungal
EP3 is an antimicrobial peptide. EP3 has antibacterial and antifungal activities. EP3 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 12.85 μg/mL. EP3 also shows antitumor activity against cancer cells, and induces cell apoptosis .

HY-B0131R

Prostaglandin E1 (Standard) Alprostadil(Standard); PGE1 (Standard)	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification	Reference Standards Prostaglandin Receptor Endogenous Metabolite
Prostaglandin E1 (Standard) is the analytical standard of Prostaglandin E1. This product is intended for research and analytical applications. Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases .

HY-N10069

Bonducellin	Flavonoids Leguminosae Caesalpinia sappan L. Plants Other Flavonoids Source Classification	Bacterial
Bonducellin is a a homoisoflavonoid, which can be isolated from Caesalpinia digyna roots. Bonducellin is a potent inhibitor of efflux pump (EP), while EP induces resistance in mycobacteria and serves as a target of anti-TB (tuberculosis) agents. Bonducellin reduces MIC of EtBr by 8-fold against M. smegmatis (MIC=62.5 mg/L) .

HY-Z8245

20b-Dihydroprogesterone Progesterone EP impurity C	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Drug Derivative
20b-Dihydroprogesterone (Compond III) is a C-21 steroid found in water beetles Cybister limbatus, C. tripunctatus and C. confuses .

HY-Z8472

Dihydromevinolin Lovastatin EP impurity E; 4a,5-Dihydromevinolin	Microorganisms Terpenoids Diterpenoids Source Classification	Endogenous Metabolite HMG-CoA Reductase (HMGCR)
Dihydromevinolin is a potent hypocholesterolemic metabolite produced by Aspergillus terreus. Dihydromevinolin is a HMG-CoA reductase inhibitor .

HY-P5703

EP5-1	Animals Ketones, Aldehydes, Acids Source Classification	Bacterial Apoptosis Fungal
EP5-1 is an antimicrobial peptide. EP5-1 has antibacterial and antifungal activities. EP5-1 also shows antitumor activity against cancer cells, and induces cell apoptosis. EP5-1 has antiviral activity against pseudorabies virus (PRV) .

HY-P5701

EP2	Animals Ketones, Aldehydes, Acids Source Classification	Bacterial Fungal
EP2 is an antimicrobial peptide. EP2 has antibacterial and antifungal activities. EP2 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 11.4 μg/mL .

HY-W007888R

2-Hydroxy-4-methylbenzaldehyde (Standard)	Structural Classification Monophenols Ketones, Aldehydes, Acids Phenols Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Prostaglandin E1 (Standard) is the analytical standard of Prostaglandin E1. This product is intended for research and analytical applications. Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases .

HY-N7748A

Epi-cryptoacetalide	Terpenoids Labiatae Samanea saman (Jacq.) Merr. Diterpenoids Plants	Estrogen Receptor/ERR Prostaglandin Receptor
Epi-cryptoacetalide is a natural diterpenoid. Epi-cryptoacetalide reveals high affinity to ER-α and PGE2 receptor (EP2 subtype) with K_i values of 0.3 μM and 1.92 μM, respectively. Epi-cryptoacetalide has anti-endometriosis activities .

Species:	Human (15) Rhesus Macaque (3) Rat (3) Mouse (6) Cynomolgus (1)
Tag:	SUMO (2) His (19) Tag Free (3) Avi (1) Myc (2) Fc (6)
Source:	HEK293 (15) CHO (1) P. pastoris (1) Sf9 insect cells (1) E. coli (10)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P75222

	Erythropoietin Protein, Cynomolgus (HEK293, His) ECYT5; EP; EPO; EPoetin; Erythropoietin; MVCD2	Cynomolgus	HEK293
	Erythropoietin Protein is a glycoprotein cytokine secreted mainly by the kidneys in response to cellular hypoxia. It regulates erythrocyte growth and balance. EPO binding to its receptor (EPOR) triggers EPOR dimerization, activating JAK2. This initiates downstream events involving effectors like STAT1 and STAT3, crucial for erythrocyte proliferation, differentiation, and maintaining optimal blood cell levels. Erythropoietin Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Erythropoietin protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P73040

	Erythropoietin Protein, Rat (sf9, His) ECYT5; EP; EPO; EPoetin; Erythropoietin; MVCD2	Rat	Sf9 insect cells
	Epo protein is a hormone that plays a vital role in regulating red blood cell production in the body.It stimulates the differentiation and maturation of red blood cells in the bone marrow.Erythropoietin Protein, Rat (sf9, His) is the recombinant rat-derived Erythropoietin protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P72167

	DBI Protein, Mouse (His-Myc) DbiAcyl-CoA-binding protein; ACBP; DiazEPam-binding inhibitor; DBI; EndozEPine; EP	Mouse	E. coli
	DBI Protein, with high affinity, binds medium- and long-chain acyl-CoA esters, potentially acting as an intracellular carrier. Moreover, DBI displaces diazepam from the benzodiazepine (BZD) recognition site on the GABA type A receptor, suggesting a neuropeptide role in modulating GABA receptor action. Structurally, as a monomer, DBI underscores the importance of its individual unit in diverse molecular interactions within cellular pathways. DBI Protein, Mouse (His-Myc) is the recombinant mouse-derived DBI protein, expressed by E. coli , with N-10*His, C-Myc labeled tag.

HY-P73038

	Erythropoietin/EPO Protein, Mouse (HEK293, solution) ECYT5; EP; EPO; EPoetin; Erythropoietin; MVCD2	Mouse	HEK293
	This gene encodes the erythropoietin (EPO) protein that is critical for regulating erythropoiesis. It is mainly expressed in the liver during fetal development and is transferred to the kidneys in adults. Erythropoietin/EPO Protein, Mouse (HEK293, solution) is the recombinant mouse-derived Erythropoietin/EPO protein, expressed by HEK293 , with tag free.

HY-P702892

	EP300 Protein, Human (His) P300	Human	E. coli
	EP300 Protein, Human (His) is the recombinant human-derived EP300, expressed by E. coli , with N-6*His labeled tag.

HY-P72166

	DBI Protein, Human (His) ACBD1; ACBP; ACBP_HUMAN; Acyl CoA binding domain containing 1; Acyl CoA binding protein; Acyl Coenzyme A binding domain containing 1; Acyl coenzyme A binding protein; Acyl-CoA-binding protein; CCK RP; CCKRP; Cholecystokinin releasing pEPtide trypsin sensitive; DBI; DiazEPam-binding inhibitor; EndozEPine; EP; GABA recEPtor modulator; MGC70414	Human	E. coli
	DBI, a versatile protein, binds medium- and long-chain acyl-CoA esters, indicating a potential intracellular carrier role. It also displaces diazepam from the benzodiazepine recognition site on the GABA type A receptor. This dual functionality suggests DBI may act as a neuropeptide, modulating GABA receptor activity. Remarkably, DBI functions as a monomer in these interactions. DBI Protein, Human (His) is the recombinant human-derived DBI protein, expressed by E. coli , with N-6*His labeled tag.

HY-P7164

	Erythropoietin/EPO Protein, Human (CHO) 2 Publications Verification rHuEPO; EPoetin; EPO	Human	CHO
	Erythropoietin/EPO is a renal cytokine that activates Akt and NF-κB signaling pathways by binding to erythroid progenitor cells EPOR. Erythropoietin/EPO regulates erythroid proliferation and differentiation and inhibits apoptosis. Erythropoietin/EPO also has angiogenic ability comparable to VEGF and can stimulate endothelial cell capillary sprouting. Erythropoietin/EPO can be used in the study of ischemic heart diseases such as anemia in end-stage renal disease. Erythropoietin/EPO Protein, Human (CHO) is a recombinant Erythropoietin/EPO protein expressed in CHO cells with tag-free.

HY-P705619

	P2ER3 Protein, Human (His) Prostaglandin E2 recEPtor EP3 subtype; PGE2-R; Prostanoid EP3 recEPtor; PTGER3; Homo sapiens; Human; PGE recEPtor EP3 subtype; G-protein coupled recEPtor; RecEPtor; Transducer	Human	E. coli
	P2ER3 Protein, Human (His) is the recombinant human-derived P2ER3, expressed by E.coli , with His abeled tag.

HY-P702963

	EP300 Protein, Mouse (His, Myc) P300; p300 HAT; Histone acetyltransferase p300	Mouse	E. coli
	EP300 Protein, Mouse (His, Myc) is the recombinant Mouse-derived EP300,with His, Myc labeled tag.

HY-P700186AF

	Animal-Free IL-1 alpha Protein, Mouse (His) Hematopoietin-1; Lymphocyte-Activating Factor (LAF); Endogenous Pyrogen (EP); Leukocyte	Mouse	E. coli
	IL-1 alpha protein is an important cytokine found intracellularly in non-hematopoietic cells that bridges innate and adaptive immunity. Binds to IL1R1 and IL1RAP to form a high-affinity receptor complex, initiates signaling through MYD88, IRAK1 or IRAK4, and activates the NF-kappa-B and MAPK pathways. Animal-Free IL-1 alpha Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-1 alpha protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P704377

	IL-1 alpha Protein, Mouse (HEK293, His) Hematopoietin-1; Lymphocyte-Activating Factor (LAF); Endogenous Pyrogen (EP); Leukocyte	Mouse	HEK293
	IL-1 alpha protein is an important cytokine found intracellularly in non-hematopoietic cells that bridges innate and adaptive immunity. Binds to IL1R1 and IL1RAP to form a high-affinity receptor complex, initiates signaling through MYD88, IRAK1 or IRAK4, and activates the NF-kappa-B and MAPK pathways. IL-1 alpha Protein, Mouse (HEK293, His) is the recombinant mouse-derived IL-1 alpha protein, expressed by HEK293, with C-His labeled tag.

HY-P74172

	EpCAM/TROP1 Protein, Rat (HEK293, His) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP1	Rat	HEK293
	The EpCAM/TROP1 protein serves as a multifunctional molecule that promotes homogeneous interactions between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) in the mucosal epithelium. This suggests a crucial role in establishing an immune barrier against mucosal infection. EpCAM/TROP1 Protein, Rat (HEK293, His) is the recombinant rat-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P75736

	EpCAM/TROP1 Protein, Rhesus Macaque (HEK293) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP2	Rhesus Macaque	HEK293
	EpCAM/TROP1 proteins play key roles in multiple processes as homogeneous interacting molecules that facilitate communication between mucosal epithelial midgut epithelial cells (IECs) and intraepithelial lymphocytes (IELs) to establish immunity against mucosal infections force. EpCAM/TROP1 Protein, Rhesus Macaque (HEK293) is the recombinant Rhesus Macaque-derived EpCAM/TROP1 protein, expressed by HEK293 , with tag free.

HY-P700037AF

	Animal-Free EpCAM/TROP1 Protein, Human (His) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP1	Human	E. coli
	The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. Animal-Free EpCAM/TROP1 Protein, Human (His) is the recombinant human-derived animal-FreeEpCAM/TROP1 protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P74173

	EpCAM/TROP1 Protein, Rat (HEK293, Fc) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP1	Rat	HEK293
	The EpCAM/TROP1 protein serves as a multifunctional molecule that promotes homogeneous interactions between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) in the mucosal epithelium. This suggests a crucial role in establishing an immune barrier against mucosal infection. EpCAM/TROP1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75737

	EpCAM/TROP1 Protein, Rhesus Macaque (HEK293, Fc) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP3	Rhesus Macaque	HEK293
	EpCAM/TROP1 proteins play key roles in multiple processes as homogeneous interacting molecules that facilitate communication between mucosal epithelial midgut epithelial cells (IECs) and intraepithelial lymphocytes (IELs) to establish immunity against mucosal infections force. EpCAM/TROP1 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77531

	EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, Fc) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP1	Human	HEK293
	SHP-2 protein is a phosphatase enzyme that plays a crucial role in cell signaling. It is involved in regulating cellular processes such as cell growth, differentiation, and survival. Dysregulation of SHP-2 protein has been implicated in various diseases, including cancer and developmental disorders. EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77532

	EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, His) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP1	Human	HEK293
	SHP-2 protein is a phosphatase enzyme that plays a crucial role in cell signaling. It is involved in regulating cellular processes such as cell growth, differentiation, and survival. Dysregulation of SHP-2 protein has been implicated in various diseases, including cancer and developmental disorders. EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P705286

	EpCAM/TROP1 Protein, Rhesus Macaque (Biotinylated, HEK293, His-Avi) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP3	Rhesus Macaque	HEK293

HY-P700095AF

	Animal-Free IL-1 alpha Protein, Human (His) Hematopoietin-1; Lymphocyte-Activating Factor (LAF); Endogenous Pyrogen (EP); IL1A; IL1F1	Human	E. coli
	IL-1 alpha protein is located in cells and is a key cytokine connecting innate immunity and adaptive immunity. After binding to IL1R1 through IL1RAP, it forms a high-affinity receptor complex, initiates a signaling cascade with adapter molecules such as MYD88, IRAK1 or IRAK4, and activates the NF-kappa-B and MAPK pathways. Animal-Free IL-1 alpha Protein, Human (His) is the recombinant human-derived animal-FreeIL-1 alpha protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P704376

	IL-1 alpha Protein, Human (HEK293, His) Hematopoietin-1; Lymphocyte-Activating Factor (LAF); Endogenous Pyrogen (EP); IL1A; IL1F1	Human	HEK293
	IL-1 alpha protein is located in cells and is a key cytokine connecting innate immunity and adaptive immunity. After binding to IL1R1 through IL1RAP, it forms a high-affinity receptor complex, initiates a signaling cascade with adapter molecules such as MYD88, IRAK1 or IRAK4, and activates the NF-kappa-B and MAPK pathways. IL-1 alpha Protein, Human (HEK293, His) is the recombinant human-derived IL-1 alpha protein, expressed by HEK293, with C-His labeled tag.

HY-P700627

	DBI Protein, Mouse (P. pastoris, His) Dbi; diazEPam binding inhibitor; EP; Acbp; ACBD1; endozEPine; acyl-CoA-binding protein; diazEPam binding inhibitor, splice form 1b	Mouse	P. pastoris
	DBI Protein, with high affinity, binds medium- and long-chain acyl-CoA esters, potentially acting as an intracellular carrier. Moreover, DBI displaces diazepam from the benzodiazepine (BZD) recognition site on the GABA type A receptor, suggesting a neuropeptide role in modulating GABA receptor action. Structurally, as a monomer, DBI underscores the importance of its individual unit in diverse molecular interactions within cellular pathways. DBI Protein, Mouse (P. pastoris, His) is the recombinant mouse-derived DBI protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P70154

	EpCAM/TROP1 Protein, Human (HEK293, His) 3 Publications Verification rHuEPithelial cell adhesion molecule/EPCAM, His; EPithelial Cell Adhesion Molecule; EP-CAM; Adenocarcinoma-Associated Antigen; Cell Surface Glycoprotein Trop-1; EPithelial Cell Surface Antigen; EPithelial Glycoprotein; EGP; EPithelial Glycoprotein 314; EGP314; hEGP314; KSA; Tumor-Associated Calcium Signa	Human	HEK293
	The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (HEK293, His) is the recombinant human-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70155

	EpCAM/TROP1 Protein, Human (HEK293, Fc) rHuEPithelial cell adhesion molecule/EPCAM, Fc ; EPithelial Cell Adhesion Molecule; EP-CAM; Adenocarcinoma-Associated Antigen; Cell Surface Glycoprotein Trop-1; EPithelial Cell Surface Antigen; EPithelial Glycoprotein 314; EGP314; Major Gastrointestinal Tumor-Associated Protein GA733-2; Tumor-Associated	Human	HEK293
	The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (HEK293, Fc) is the recombinant human-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P704581

	EpCAM/TROP1 Protein, Human (HEK293, mFc) rHuEPithelial cell adhesion molecule/EPCAM, His; EPithelial Cell Adhesion Molecule; EP-CAM; Adenocarcinoma-Associated Antigen; Cell Surface Glycoprotein Trop-1; EPithelial Cell Surface Antigen; EPithelial Glycoprotein; EGP; EPithelial Glycoprotein 314; EGP314; hEGP314; KSA; Tumor-Associated Calcium Signa	Human	HEK293
	EpCAM/TROP1 Protein, Human (HEK293, mFc) is the recombinant human-derived EpCAM/TROP1 protein, expressed by HEK293, with C-mFc tag.

HY-P704582

	EpCAM/TROP1 Protein, Human (HEK293, Llama Fc) rHuEPithelial cell adhesion molecule/EPCAM, His; EPithelial Cell Adhesion Molecule; EP-CAM; Adenocarcinoma-Associated Antigen; Cell Surface Glycoprotein Trop-1; EPithelial Cell Surface Antigen; EPithelial Glycoprotein; EGP; EPithelial Glycoprotein 314; EGP314; hEGP314; KSA; Tumor-Associated Calcium Signa	Human	HEK293
	EpCAM/TROP1 Protein, Human (HEK293, Llama Fc) is the recombinant human-derived EpCAM/TROP1 protein, expressed by HEK293, with C-Llama Fc tag.

HY-P72201

	GAPDH Protein, Human (His-SUMO) G3P_HUMAN; G3PD; G3PDH; GAPD; GAPDH; Glyceraldehyde 3 phosphate dehydrogenase; glyceraldehyde 3-PDH; Glyceraldehyde-3-phosphate dehydrogenase; HEL-S-162EP; KNC-NDS6; MGC102544; OCAS; p38 component; OCT1 coactivator in S phase; 38-KD component; pEPtidyl cysteine S nitrosylase GAPDH	Human	E. coli
	GAPDH, a multifunctional protein, acts as a key enzyme in glycolysis, catalyzing the conversion of G3P. It also functions as a nitrosylase, impacting nuclear processes. In addition, it influences cytoskeleton organization, associates with CHP1, participates in transcript-selective translation inhibition, contributes to immune responses, and mediates nuclear events through S-nitrosylation of target proteins. GAPDH Protein, Human (His-SUMO) is the recombinant human-derived GAPDH protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

HY-P72183

	EpCAM/TROP1 Protein, Human (His-SUMO) 17 1A; 323/A3; Adenocarcinoma associated antigen; Adenocarcinoma-associated antigen; Antigen identified by monoclonal AUA1; AUA1; CD326; CD326 antigen; Cell surface glycoprotein Trop 1; Cell surface glycoprotein Trop 2; Cell surface glycoprotein Trop-1; CO 17A; CO17 1A; CO17A; DIAR5; EGP 2; EGP; EGP2; EGP314; EGP40; EP CAM; EP-CAM; EPCAM; EPCAM_HUMAN; EPCAM1; EPithelial cell adhesion molecule; EPithelial Cell Adhesion Molecule Intracellular Domain EPCAM-ICD; ; EPithelial cell surface antigen; EPithelial cellular adhesion molecule; EPithelial glycoprotein 1; EPithelial glycoprotein 314; EPithelial glycoprotein; ESA; GA733 1; GA733 2; GA733-2; gastrointestinal tumor-associated antigen 2; 35-KD glycoprotein; gp4; hEGP 2; hEGP314; HNPCC8; Human EPithelial glycoprotein 2; KS 1/4 antigen; KS1/4; KSA; Ly74; Lymphocyte antigen 74; M1S 1; M1S2; M4S1; Major gastrointestinal tumor associated protein GA733 2; Major gastrointestinal tumor-associated protein GA733-2; mEGP314; Membrane component chro	Human	E. coli
	The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-100441S2

Treprostinil-d9
Treprostinil-d₉ (UT-15-d₉) is the deuterium-labeled Treprostinil (HY-100441) . Treprostinil (UT-15) is a potent DP1 and *EP2* agonist with EC₅₀ values of 0.6±0.1 and 6.2±1.2 nM, respectively.

HY-100441S1

Treprostinil-13C2,d1
Treprostinil- ¹³C₂,d is the ¹³C- and deuterium labeled Treprostinil. Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.

HY-100441S3

Treprostinil-d7
Treprostinil-d7 (UT-15-d7) is a deuterated version of Treprostinil (HY-100441). Treprostinil is a highly potent DP1 and EP2 agonist with EC50s of 0.6 nM and 6.2 nM, respectively .

HY-160261S

EP300/CBP-IN-2
EP300/CBP-IN-2 is a potent *EP300/CBP* inhibitor that has good activity in vivo. EP300/CBP-IN-2 can be used for the research of cancer .

HY-144242S

Voriconazole EP impurity D-d3
Voriconazole EP impurity D-d₃ is the deuterium labeled Voriconazole EP impurity D .

HY-143990S

Modafinil EP impurity B-d5
Modafinil EP impurity B-d₅ is the deuterium labeled Modafinil EP impurity B .

HY-142592S

Clozapine EP impurity D-d8
Clozapine EP impurity D-d₈ is the deuterium labeled Clozapine EP impurity D .

HY-143941S

Hydroxychloroquine EP impurity D-d5 dihydrochloride
Hydroxychloroquine EP impurity D-d₅ (dihydrochloride) is the deuterium labeled Hydroxychloroquine EP impurity D dihydrochloride .

HY-144203S

Trospium EP impurity C-d8 chloride
Trospium EP impurity C-d₈ (chloride) is the deuterium labeled Trospium EP impurity C chloride .

HY-143907S

Atorvastatin EP impurity H-d5
Atorvastatin EP impurity H-d₅ is the deuterium labeled Atorvastatin EP impurity H .

HY-144221S

Tiotropium bromide EP impurity A-d6
Tiotropium bromide EP impurity A-d₆ is the deuterium labeled Tiotropium bromide EP impurity A .

HY-143997S

(Rac)-Nicotine EP impurity A-d4 hydrochloride
(Rac)-Nicotine EP impurity A-d₄ (hydrochloride) is the deuterium labeled (Rac)-Nicotine EP impurity A hydrochloride .

HY-143982S

Mianserin EP impurity E-d4 hydrochloride
Mianserin EP impurity E-d₄ (hydrochloride) is the deuterium labeled Mianserin EP impurity E hydrochloride .

HY-13204S2

rel-Biperiden EP impurity A-d5
rel-Biperiden EP impurity A-d₅ is deuterium labeled Biperiden (hydrochloride).

HY-13204S3

rel-Biperiden EP impurity B-d5
rel-Biperiden EP impurity B-d₅ is deuterium labeled Biperiden (hydrochloride).

HY-W336012S

Metoprolol EP impurity O-d7 hydrochloride
Metoprolol EP impurity O-d₇ (hydrochloride) is the deuterium labeled 3,3'-(Isopropylazanediyl)bis(1-(4-(2-methoxyethyl)phenoxy)propan-2-ol) .

HY-W704036

Tolterodine Ep Impurity D-d7
Tolterodine Ep Impurity D-d₇ (rac Desisopropyl tolterodine methyl ether-d₇) is the deuterium labeled Tolterodine Ep Impurity D (HY-Z12547).

HY-B0131S2

Prostaglandin E1-d9
Prostaglandin E1-d₉ is deuterium labeled Prostaglandin E1.Prostaglandin E1 is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inh

HY-B0131S

Prostaglandin E1-d4

Prostaglandin E1-d₄ is the deuterium labeled Prostaglandin E1. Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with K_is of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases .

HY-152066S

Chlorprothixene-d3
Chlorprothixene-d₃ is the deuterium labeled Chlorprothixene Ep Impurity F (HY-Z16039).

HY-A0251AS

Cefpodoxime proxetil EP impurity A-d3 sodium
Cefpodoxime-d₃ (sodium) is deuterium labeled Cefpodoxime sodium.

HY-W742491

Betamethasone 21-Acetate-d3 17-Propionate
Betamethasone 21-Acetate-d₃ 17-Propionate is the deuterium labeled Betamethasone Dipropionate EP Impurity D (HY-148661).

HY-Z1430S

(3R,4S)-Paroxetine-d4 hydrochloride
Paroxetine EP impurity D-d₄ (hydrochloride) is deuterium labeled (3R,4S)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine (Paroxetine Impurity).

HY-16504S

Treprostinil-13C2-d1 Sodium
Treprostinil- ¹³C₂-d₁ (Sodium) (UT-15- ¹³C₂-d₁(sodium)) is deuterium and ¹³C labeled Treprostinil (sodium). Treprostinil (UT-15) sodium is a potent DP1 and *EP2* agonist with EC₅₀ values of 0.6±0.1 and 6.2±1.2 nM, respectively.

HY-179245S

(±)EP-0226A-d4
(±)EP-0226A-d₄ is the deuterium labeled (±)EP-0226A.

HY-W101675S

Rosuvastatin EP impurity F-d3
Rosuvastatin EP impurity F-d₃ is the deuterium labeled Rosuvastatin EP impurity F.

HY-166891S

Tiotropium EP Impurity G-d3Iodide
Tiotropium EP Impurity G-d₃(Iodide) is deuterium labeled Tiotropium EP Impurity G .

Host:	Mouse (8) Rabbit (8)
Reactivity:	Human (16) Rat (8) Mouse (9) Monkey (3) Cow (1) Pichia pastoris (1) Saccharomyces cerevisiae (1) Hamster (1)
Application:	IHC-P (11) ICC/IF (11) IP (4) IHC-F (3) WB (15) FC (5) ELISA (5)
Isotype:	IgG (9) IgG1 (4) IgG2b (2) IgM (1)
Conjugation:	Non-conjugated (16) Biotin (3)
Clonality:	Polyclonal (2) Monoclonal (10) Recombinant (5)
Modification:	Unmodified (12)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P87041

	Phosphoserine aminotransferase Antibody (YA6734) EC 2.6.1.52 antibody; Endometrial progesterone induced protein antibody; EP; IP : antibody; MGC1460 antibody; NLS2 antibody; Phosphohydroxythreonine aminotransferase antibody; phosphoserine aminotransferase 1 antibody; Phosphoserine aminotransferase antibody; PSA antibody; PSAT antibody; EC 2.6.1.52 antibody; Endometrial progesterone induced protein antibody; EP; IP : antibody; MGC1460 antibody; NLS2 antibody; Phosphohydroxythreonine aminotransferase antibody; phosphoserine aminotransferase 1 antibody; Phosphoserine aminotransferase antibody; PSA antibody; PSAT antibody; Psat1 antibody; PSATD antibody; SERC_HUMAN antibody;	WB, IHC-P, FC, IP	Human, Mouse, Rat
	Phosphoserine aminotransferase Antibody (YA6734) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phosphoserine aminotransferase.

HY-P83597

	Prostaglandin E Receptor EP2 Antibody (YA3342) 1 Publications Verification EP2; PGE2 recEPtor EP2 subtype; Prostaglandin E recEPtor 2 subtype EP2 53kDa; Prostaglandin E2 recEPtor EP2 subtype; Prostanoid EP2 recEPtor; Ptger2	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat, Cow
	Prostaglandin E Receptor EP2 Antibody (YA3342) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Prostaglandin E Receptor EP2.

HY-P83908

	EPO Antibody (YA3605) EP; MVCD2; MGC138142; EPO	WB, ICC/IF, ELISA	Human
	EPO Antibody (YA3605) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EPO.

HY-P83908A

	EPO Antibody (YA3605)(PBS only) EP; MVCD2; MGC138142; EPO	WB, ICC/IF, ELISA	Human
	EPO Antibody (YA3605) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EPO.

HY-P80075

	CDC42EP1 Antibody (YA517)	WB	Human
	CDC42EP1 Antibody (YA517) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC42EP1.

HY-P88470

	NLN Antibody (YA8154) AGTBP; EP24.16; MEP; MOP	WB, IHC-P, ICC/IF, FC	Human, Rat, Monkey, Mouse
	NLN Antibody (YA8154) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NLN.

HY-P80954

	GAPDH Antibody (YA848) G3PD; GAPD; HEL-S-162EP	WB	Human, Monkey, Rat, Mouse, Saccharomyces cerevisiae, Pichia pastoris, Hamster
	GAPDH Antibody (YA848) is a non-conjugated and Mouse origined IgM monoclonal antibody. It can be used as a loading control antibody.

HY-P88470A

	NLN Antibody (YA8154)(PBS only) AGTBP; EP24.16; MEP; MOP	WB, IHC-P, ICC/IF, FC	Human, Rat, Monkey, Mouse
	NLN Antibody (YA8154) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NLN.

HY-P88448

	THOP1 (Thimet Oligopeptidase) Antibody (YA8132) EP24.15; MEPD_HUMAN; MP78; TOP	WB, IHC-P	Human, Mouse, Rat
	THOP1 (Thimet Oligopeptidase) Antibody (YA8132) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to THOP1 (Thimet Oligopeptidase).

HY-P88448A

	THOP1 (Thimet Oligopeptidase) Antibody (YA8132)(PBS only) EP24.15; MEPD_HUMAN; MP78; TOP	WB, IHC-P	Human, Mouse, Rat
	THOP1 (Thimet Oligopeptidase) Antibody (YA8132) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to THOP1 (Thimet Oligopeptidase).

HY-P80775

	p300 Antibody EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300	ICC/IF, WB, IHC-F, IHC-P, ELISA	Human, Mouse, Rat
	p300 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to p300.

HY-P85861

	p300 Antibody (YA5553) EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300	WB, ICC/IF, ELISA	Human, Mouse
	p300 Antibody (YA5553) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to p300.

HY-P84932

	Mucin 1 Antibody MUC1; PUM; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; EPisialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic EPithelial mucin; PEM; Tumor-associated EP	IHC-P, ICC/IF, ELISA	Human
	Mucin 1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Mucin 1.

HY-P83341

	Mucin 1 Antibody (YA3086) MUC1; PUM; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; EPisialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic EPithelial mucin; PEM; Tumor-associated EP	WB, IHC-P, ICC/IF, IP, FC	Human
	Mucin 1 Antibody (YA3086) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mucin 1.

HY-P80657

	EpCAM Antibody (YA458) EPCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1; EPithelial cell adhesion molecule; EP-CAM; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; EPithelial cell surface antigen; EPithelial glycoprotein; EGP; EPithelial glycoprotein 314;	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	EpCAM Antibody (YA458) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EpCAM.

HY-P80657A

	EpCAM Antibody (YA458)(PBS only) EPCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1; EPithelial cell adhesion molecule; EP-CAM; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; EPithelial cell surface antigen; EPithelial glycoprotein; EGP; EPithelial glycoprotein 314;	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	EpCAM Antibody (YA458) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EpCAM.

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