49 Results for "

G-CSF

" in MedChemExpress (MCE) Product Catalog:
Products (49)

49 Results for "G-CSF" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
111
111 Publications Verification
Cat. No.: HY-10046
CAS No.: 110078-46-1
Purity:  99.90%
Synonyms: AMD 3100; JM3100; SID791
Target:  

CXCR HIV

Plerixafor (AMD 3100) is a selective CXCR4 antagonist with an IC50 of 44 nM. Plerixafor, an immunostimulant and a hematopoietic stem cell (HSC) mobilizer, is an allosteric agonist of CXCR7. Plerixafor inhibits HIV-1 and HIV-2 replication with an EC50 of 1-10 nM .
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2
2 Cited Publications
Cat. No.: HY-P70554
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Granulocyte colony-stimulating factor; CSF3; G-CSF
Species:  
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2
2 Cited Publications
Cat. No.: HY-P70422
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Granulocyte Colony-Stimulating Factor; G-CSF; Pluripoietin; Filgrastim; Lenograstim; CSF3; C17orf33; GCSF
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-N0620
CAS No.: 102841-43-0
Mulberroside C is one of the main bioactive components in white mulberry (Morus alba L.). Mulberroside C exhibits antiplatelet, antiviral and neutrophil-regulating activities, and binds to EV-A71 VP1 with a Kd value of 1.289 nM. Mulberroside C reduces the phosphorylation level of ERK, promotes the phosphorylation of IP3RI at the Ser 1756 site, and decreases calcium influx and calcium mobilization. Mulberroside C inhibits the expression of P-selectin (P-selectin). Mulberroside C upregulates the cyclic nucleotide signaling pathway in human platelets. Mulberroside C binds to IL-23R, upregulates the expression of G-CSF, GM-CSF and RASGRP1, and activates the RAS/ERK signaling pathway. Mulberroside C promotes neutrophil maturation, accelerates the recovery of leukopenia, and enhances the antibacterial activity of neutrophils. Mulberroside C inhibits the replication of hepatitis C virus in replicon cells. Mulberroside C prevents the uncoating and genome release of EV-A71, and inhibits the synthesis of viral proteins and RNA. Mulberroside C can be used in studies related to thrombosis-mediated cardiovascular diseases, chemotherapy- and radiotherapy-induced leukopenia, hepatitis C virus infection, and hand, foot and mouth disease .
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1
1 Cited Publications
Cat. No.: HY-P73073
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Granulocyte Colony-Stimulating Factor; G-CSF; CSF3; C17orf33
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1
1 Cited Publications
Cat. No.: HY-P7068
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim
Species:  
Source:  
CHO
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1
1 Cited Publications
Cat. No.: HY-P7093A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rRtG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim
Species:  
Rat
Source:  
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1
1 Cited Publications
Cat. No.: HY-P700083AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF-3; MGI-1G; GM-CSF beta; pluripoietin
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1
1 Cited Publications
Cat. No.: HY-P71179
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Olfactomedin-4; OLM4; Antiapoptotic protein GW112; G-CSF-stimulated clone 1 protein; hGC-1; hOLfD; OLFM4; GW112
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Cat. No.: HY-N3018
CAS No.: 499-40-1
Synonyms: 6-O-α-D-Glucopyranosyl-D-glucose; D-Isomaltose
Isomaltose (6-O-α-D-Glucopyranosyl-D-glucose) is a glucose disaccharide. Isomaltose induces G-CSF secretion via heat-induced oxidative polymerization of glucose groups into high-molecular-weight compounds. Isomaltose modulates cecal bacterial cluster structure in mice. Isomaltose exhibits low glycemic index, slow hydrolysis, and prebiotic properties. Isomaltose reduces in vivo Cryptosporidium parvum colonization in neonatal mice. Isomaltose can be used for the research of Cryptosporidium parvum infection .
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Cat. No.: HY-P10408
CAS No.: 1906866-53-2
Candidalysin is a cytolytic peptide toxin secreted by the fungus Candida albicans. Candidalysin drives epithelial immune responses by activating the EGFR-MAPK signaling pathway, inducing MMP expression and calcium influx, and regulating the c-Fos transcription factor and MKP1 via p38 MAPK and ERK1/2 respectively. Candidalysin is essential for mucosal and systemic infections, activating NLRP3 to promote inflammatory responses, neutrophil recruitment, and Th17 immunity. Candidalysin activates LDH causing membrane damage and exhibiting cytotoxicity
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Cat. No.: HY-17028
CAS No.: 405165-61-9
Besifloxacin Hydrochloride is a fourth generation fluoroquinolone antibiotic. Besifloxacin Hydrochloride is a DNA gyrase and topoisomerase IV inhibitor. Besifloxacin Hydrochloride has broad-spectrum antibacterial activity, it is effective against Gram-negative and Gram-positive aerobic and anaerobic strains and reduces the incidence of drug resistance. Besifloxacin Hydrochloride has anti-inflammatory activity. Besifloxacin Hydrochloride can be used in bacterial conjunctivitis research .
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Cat. No.: HY-P99440
CAS No.: 2416593-08-1
Synonyms: CSL-324

Target:  

c-Fms JAK STAT

Research Areas:  

Inflammation/Immunology

Anumigilimab (CSL-324) is an human IgG4 mAb against human granulocyte colony-stimulating factor (G-CSF) receptor. Anumigilimab can be used for increasing numbers of neutrophils at sites of inflammation .
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Cat. No.: HY-P99879
CAS No.: 2200269-79-8
Synonyms: Benegrastim; Bineuta; F 627

Target:  

STAT

Research Areas:  

Inflammation/Immunology

Efbemalenograstim alfa (F 627) is a recombinant fusion protein. Efbemalenograstim alfa is a long acting dimeric granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2)-Fc fragment with a peptide linker. Efbemalenograstim alfa induces the production of white blood cells .
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Cat. No.: HY-139410
CAS No.: 9005-46-3
Sodium caseinates is a kind of sodium salts of major milk proteins, which act as protein-based biopolymers and innate immune system activators. Sodium caseinates induce granulopoiesis, activation and differentiation, promote the production of M-CSF, and increase serum levels of G-CSF and GM-CSF. Sodium caseinates inhibit the proliferation and reduce the viability of leukemia macrophage-like cells, thereby significantly improving the survival rate of mice inoculated with leukemia cells. Sodium caseinates can serve as carriers for probiotics in edible films and exhibit anti-Listeria activity. Sodium caseinates effectively protect vitamin A from degradation, enhance its stability, bioaccessibility and bioavailability, and regulate protein digestibility when complexed with vitamin A. Sodium caseinates can be applied to research related to acute monocytic leukemia and vitamin A deficiency .
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Cat. No.: HY-W014134
CAS No.: 74938-88-8
Synonyms: p-Amidinophenylmethylsulfonylfluoride hydrochloride
Target:  

Ser/Thr Protease

Research Areas:  

Inflammation/Immunology

p-APMSF (p-Amidinophenylmethylsulfonylfluoride) hydrochloride is a serine protease and trypsin inhibitor with the characteristic of rapid onset of action. p-APMSF hydrochloride reduces the enzymatic hydrolysis of recombinant human G-CSF in rat pulmonary mucosa. Combined intratracheal treatment with p-APMSF hydrochloride and Laureth-9 significantly enhances its absorption efficiency in rat lungs. Following intranasal administration, p-APMSF hydrochloride does not increase the concentration of recombinant human G-CSF in rat plasma, nor does it alter the effect of G-CSF on inducing an increase in total white blood cell count .
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Cat. No.: HY-176464
CAS No.: 1206619-37-5
Target:  

TRP Channel

Research Areas:  

Inflammation/Immunology

SK2220691 is a potent TRPV4 inhibitor. SK2220691 inhibits pulmonary edema induced by GSK1016790. SK2220691 inhibits HCl-induced increases in key factors such as VEGF, keratinocyte-derived chemokine (KC; CXCL1), and granulocyte colony-stimulating factor (GCSF) .
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Cat. No.: HY-P99913
CAS No.: 1384099-30-2

Target:  

c-Fms

Research Areas:  

Inflammation/Immunology Cancer

Eflapegrastim is a composite protein consisting of a genetically modified granulocyte-colony stimulating factor (GCSF) molecule linked via a chemical bond to an IgG4 Fc fragment (LAPS-carrier). Eflapegrastim targets to G-CSF receptor (c-Fms). Eflapegrastim stimulates proliferation and differentiation of neutrophil progenitor cells and maintains stable numbers of mature and functional neutrophils. Eflapegrastim also shortens the duration of neutropenia .
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Cat. No.: HY-P990963
CAS No.: 2817686-50-1

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology Cancer

Albipagrastim alfa is a long-acting granulocyte colony-stimulating factor (G-CSF), which is formed by the fusion of highly active recombinant G-CSF and human serum albumin (HSA). Albipagrastim alfa can significantly inhibit the clearance pathway mediated by the G-CSF receptor. Albipagrastim alfa can be used in tumor-related research .
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Cat. No.: HY-178714
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

JNJ627 is a small molecule allosteric inhibitor of IL-17A with a KD of 92 nM. JNJ627 effectively inhibits the binding of IL-17A and IL-17RA, with an IC50 value of 16 nM. JNJ627 is capable of inhibiting the secretion of G-CSF (granulocyte colony-stimulating factor) caused by IL-17A stimulation. JNJ627 can be used for the study of autoimmune diseases (such as psoriasis) .
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