26 Results for "

GAL2

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "GAL2" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P1723
CAS No.: 1370290-58-6
Synonyms: Neuropeptide Q
Spexin (Neuropeptide Q) is a selective agonist of galanin receptors GAL2 and GAL3, and is a conserved peptide that functions as a neurotransmitter/neuromodulator and endocrine factor. Spexin can function through both central and peripheral actions. Spexin upregulates Beclin 1 to inhibit ferroptosis induced by excessive autophagy, reduces the uptake of long-chain fatty acids by adipocytes, and regulates energy metabolism by increasing lipid oxidation (e.g., reducing the respiratory exchange ratio in rodents). Spexin improves cardiac function in the Doxorubicin hydrochloride (HY-15142)-induced cardiotoxicity model, protects mitochondrial membrane potential, and reduces iron accumulation and lipid peroxidation. Spexin can be used to study obesity and its related metabolic disorders, cardiovascular diseases (e.g., cardioprotection), and side effects of tumor chemotherapy [2] .
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Cat. No.: HY-P1135
CAS No.: 1172089-00-7
Research Areas:  

Neurological Disease

M1145, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher affinity over GalR3 (Ki=497 nM). M1145 has an additive effect on the signal transduction of galanin .
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Cat. No.: HY-P1132A
Research Areas:  

Neurological Disease

Galanin (1-29)(rat, mouse) TFA is a non-selective galanin receptor agonist, with Kis of 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3, respectively. Anticonvulsant effect [2].
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Cat. No.: HY-P1131
CAS No.: 860790-38-1
Research Areas:  

Cardiovascular Disease

M617 is a selective galanin receptor 1 (GAL1) agonist, with Kis of 0.23 and 5.71 nM for GAL1 and GAL2, respectively. M617, acting through its central GAL1, can promote GLUT4 expression and enhance GLUT4 content in the cardiac muscle of type 2 diabetic rats [2].
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Cat. No.: HY-103536
CAS No.: 475115-35-6
Research Areas:  

Neurological Disease

Galnon is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon exhibits anticonvulsant and anxiolytic effects [2].
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Cat. No.: HY-P1132
CAS No.: 114547-31-8
Research Areas:  

Neurological Disease

Galanin (1-29)(rat, mouse) is a non-selective galanin receptor agonist, with Kis of 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3 respectively. Anticonvulsant effect [2].
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Cat. No.: HY-103536A
CAS No.: 1217448-19-5
Purity:  99.15%
Research Areas:  

Neurological Disease

Galnon TFA is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon TFA exhibits anticonvulsant and anxiolytic effects [2].
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Cat. No.: HY-P1723A
Synonyms: Neuropeptide Q TFA
Spexin (Neuropeptide Q) TFA is a selective agonist of galanin receptors GAL2 and GAL3, and is a conserved peptide that functions as a neurotransmitter/neuromodulator and endocrine factor. Spexin TFA can function through both central and peripheral actions. Spexin TFA upregulates Beclin 1 to inhibit ferroptosis induced by excessive autophagy, reduces the uptake of long-chain fatty acids by adipocytes, and regulates energy metabolism by increasing lipid oxidation (e.g., reducing the respiratory exchange ratio in rodents). Spexin TFA improves cardiac function in the Doxorubicin hydrochloride (HY-15142)-induced cardiotoxicity model, protects mitochondrial membrane potential, and reduces iron accumulation and lipid peroxidation. Spexin TFA can be used to study obesity and its related metabolic disorders, cardiovascular diseases (e.g., cardioprotection), and side effects of tumor chemotherapy [2] .
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Cat. No.: HY-P1135A
Research Areas:  

Neurological Disease

M1145 TFA, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 TFA shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher affinity over GalR3 (Ki=497 nM). M1145 TFA has an additive effect on the signal transduction of galanin .
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Cat. No.: HY-P1128
CAS No.: 88813-36-9
Research Areas:  

Metabolic Disease

Galanin (swine), a neuropeptide, consists of 29 amino acids and contains a C-terminal amidated glycine. Galanin (swine) inhibits basal and stimulated insulin secretion both in vivo and in vitro under a variety of experimental conditions. Galanin (swine) is a galanin receptor agonist with pKis of 9.63, 9.49, 9.02, 8.98, 8.01 and 8.14 at human GAL1, rat GAL1, human GAL2, rat GAL2, human GAL3 and rat GAL3 respectively .
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Cat. No.: HY-P1128A
Research Areas:  

Metabolic Disease

Galanin (swine) TFA, a neuropeptide, consists of 29 amino acids and contains a C-terminal amidated glycine. Galanin (swine) inhibits basal and stimulated insulin secretion both in vivo and in vitro under a variety of experimental conditions. Galanin (swine) TFA is a galanin receptor agonist with pKis of 9.63, 9.49, 9.02, 8.98, 8.01 and 8.14 at human GAL1, rat GAL1, human GAL2, rat GAL2, human GAL3 and rat GAL3 respectively .
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Cat. No.: HY-P1131A
Research Areas:  

Cardiovascular Disease

M617 TFA is a selective galanin receptor 1 (GAL1) agonist, with Kis of 0.23 and 5.71 nM for GAL1 and GAL2, respectively. M617 TFA, acting through its central GAL1, can promote GLUT4 expression and enhance GLUT4 content in the cardiac muscle of type 2 diabetic rats [2].
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Cat. No.: HY-103536AR
CAS No.: 1217448-19-5
Galnon TFA (Standard) is the analytical standard of Galnon TFA (HY-103536A). This product is intended for research and analytical applications. Galnon TFA is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon TFA exhibits anticonvulsant and anxiolytic effects [2].
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Cat. No.: HY-RS13847
Research Areas:  

Others

ST3GAL2 Human Pre-designed siRNA Set A contains three designed siRNAs for ST3GAL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS13853
Research Areas:  

Others

ST6GAL2 Human Pre-designed siRNA Set A contains three designed siRNAs for ST6GAL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS27163
Research Areas:  

Others

St6gal2 Rat Pre-designed siRNA Set A contains three designed siRNAs for St6gal2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-E70149
Synonyms: ST6GAL2
ST6 Gal Sialyltransferase 2 (EC:2.4.3.1, ST6GAL2) catalyzes the transfer of sialic acid from CMP to an oligosaccharide substrate. ST6 Gal Sialyltransferase 2 plays an important role in schizophrenic research .
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Cat. No.: HY-E70146
Synonyms: EC:2.4.3.4; ST3GAL2
ST3 beta-Gal alpha-2,3-Sialyltransferase 2 (EC:2.4.3.4, ST3GAL2) catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates .
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Cat. No.: HY-W145538
CAS No.: 129865-06-1
Synonyms: Xyloglucan nonasaccharide
Nonasaccharide Glc Xyl Gal is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-P5896
CAS No.: 859843-84-8
Research Areas:  

Neurological Disease

Ala5-Galanin (2-11) is a galanin receptor 2 (GAL2R) specific agonist with a Ki of 258 nM .
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