516 Results for "

Glycerol

" in MedChemExpress (MCE) Product Catalog:
Products (516)

516 Results for "Glycerol" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-126073
CAS No.: 672286-03-2
Purity:  99.46%
Target:  

Aquaporin

Research Areas:  

Inflammation/Immunology Cancer

DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC50 of ~0.1-0.4 μM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9 .
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5
5 Cited Publications
Cat. No.: HY-P1956
CAS No.: 70024-90-7
Synonyms: HSA
Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO ) in the vascular wall, contributing to the reduction of blood pressure .
This product is recombinant Human Serum Albumin expressed in a microbial expression system.
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4
4 Cited Publications
Cat. No.: HY-N8461
CAS No.: 2134-29-4
Synonyms: 3-Hydroxypropionaldehyde; 3-Hydroxypropanal
Reuterin is a broad-spectrum antimicrobial agent active against Gram positive and Gram negative bacteria, as well as yeasts, moulds and protozoa. Reuterin is produced by specific strains of Lactobacillus reuteri during anaerobic metabolism of glycerol. Reuterin also demonstrates potent antimicrobial activity against a broad panel of human and poultry meat campylobacter spp. Isolates .
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3
3 Cited Publications
Cat. No.: HY-B1659
CAS No.: 56-81-5
Synonyms: Trihydroxypropane
Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis.
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2
2 Cited Publications
Cat. No.: HY-P2733
CAS No.: 9046-28-0
Synonyms: GPO
Glycerol-3-phosphate oxidase, E. coli (GPO) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase, E. coli is the skeleton of phospholipids in membrane lipids, and also a substrate in the respiratory chain. Glycerol-3-phosphate oxidase, E. coli produces electrons through oxidation. Glycerol-3-phosphate oxidase, E. coli is an enzyme with important functions in the field of biochemistry, and is widely used in medical testing and scientific research .
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2
2 Cited Publications
Cat. No.: HY-116934
CAS No.: 3158-56-3
Purity:  99.30%
Synonyms: Adipostatin A
5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti .
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2
2 Cited Publications
Cat. No.: HY-112489
CAS No.: 1158383-34-6
Purity:  99.95%
Target:  

Acyltransferase

Research Areas:  

Metabolic Disease

FSG67 is a glycerol 3-phosphate acyltransferase (GPAT) inhibitor with an IC50 of 24 μM .
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2
2 Cited Publications
Cat. No.: HY-108355
CAS No.: 120166-69-0
Purity:  ≥98.0%
Target:  

PKC

Research Areas:  

Cancer

R59949 is a pan diacylglycerol kinase (DGK) inhibitor with an IC50 of 300 nM. R59949 strongly inhibits the activity of type I DGK α and γ and moderately attenuates the activity of type II DGK θ and κ. R59949 activates protein kinase C (PKC) by enhancing the levels of the endogenous ligand diacyl glycerol .
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1
1 Cited Publications
Cat. No.: HY-B2087
CAS No.: 611168-24-2
Synonyms: HPN-100
Target:  

Sigma Receptor

Research Areas:  

Cardiovascular Disease

Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pKi of 8.02. Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger agent .
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1
1 Cited Publications
Cat. No.: HY-131897
CAS No.: 65914-84-3
Purity:  ≥98.0%
1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity .
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1
1 Cited Publications
Cat. No.: HY-131648
CAS No.: 86390-77-4
Purity:  ≥99.0%
1-Oleoyl-2-acetyl-sn-glycerol is a cell-permeable analog of diacylglycerol (DAG) and can activate Protein kinase C (PKC). 1-Oleoyl-2-acetyl-sn-glycerol can activate the TRPC channels-mediated specific Ca 2+ influx. 1-Oleoyl-2-acetyl-sn-glycerol can stimulate superoxide-generation from human neutrophils. 1-Oleoyl-2-acetyl-sn-glycerol stimulates the formation of phosphatidylinositol 4-phosphate in intact human platelets. 1-Oleoyl-2-acetyl-sn-glycerol can stimulate ascites tumor cell proliferation .
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1
1 Cited Publications
Cat. No.: HY-113437A
CAS No.: 169051-60-9
Purity:  ≥98.0%
1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite . It is used in the generation of micelles, liposomes, and artificial membranes.
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1
1 Cited Publications
Cat. No.: HY-Y0335
CAS No.: 96-26-4
Synonyms: Dihydroxyacetone
1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans. 1,3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227) .
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1
1 Cited Publications
Cat. No.: HY-148685
CAS No.: 26530-26-7
Purity:  98.76%
Research Areas:  

Cancer

KM04416, an isothiazolone derivative, is a potent glycerol-3-phosphate dehydrogenase (GPD2) inhibitor. KM04416 significantly inhibits PNT1A cell proliferation .
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1
1 Cited Publications
Cat. No.: HY-133948
CAS No.: 37515-61-0
Purity:  ≥99.0%
Synonyms: Glyceryl palmitoleate
1-Palmitoleoyl glycerol is a biologically active monoacylglycerol. It increases daunomycin accumulation, shown to inhibit P-glycoprotein in Caco-2 cells. 1-Palmitoleoyl glycerol induces thymocyte apoptosis.
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1
1 Cited Publications
Cat. No.: HY-161834
CAS No.: 2140901-88-6
RG100204 is a selective, orally available inhibitor of the aquaporin AQP9. RG100204 directly inhibits AQP9 channel function, preventing the transmembrane transport of water, glycerol, and H 2O 2. RG100204 reduces the activation of the NLRP3 inflammasome and p38 MAPK signaling pathways, thereby alleviating inflammation and pyroptosis. RG100204 reduces multi-organ dysfunction in a mouse sepsis model and shows glucose-regulating effects in diabetic db/db mice .
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Cat. No.: HY-113128A
Purity:  99.90%
sn-Glycerol 3-phosphate lithium is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate lithium from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate lithium for lipid metabolism .
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Cat. No.: HY-B0264
CAS No.: 93-14-1
Synonyms: Guaiacol glyceryl ether; Guaiphenesin; Glycerol guaiacolate
Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough .
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Cat. No.: HY-113128
CAS No.: 17989-41-2
Purity:  ≥98.0%
sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism .
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Cat. No.: HY-111346
CAS No.: 2277-28-3
Purity:  ≥98.0%
Synonyms: 1-Linoleoyl-rac-Glycerol; 1-Monolinolein
1-Linoleoyl glycerol is a LpPLA2 inhibitor. 1-Linoleoyl glycerol acts as a precursor for synthesizing various functional lipids, such as phospholipids. 1-Linoleoyl glycerol mitigates inflammation induced by Apolipoprotein CIII (reduction of IL-6) .
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