131 Results for "

Heparin

" in MedChemExpress (MCE) Product Catalog:
Products (131)

131 Results for "Heparin" in MCE Product Catalog:

61
61 Publications Verification
Cat. No.: HY-17567A
CAS No.: 9041-08-1
Synonyms: Sodium Heparin; Sodium Heparinate
Heparin sodium salt (Sodium heparin) is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa. Heparin sodium salt significantly inhibits exosome-cell interactions.
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9
9 Cited Publications
Cat. No.: HY-17567
CAS No.: 9005-49-6
Heparin is a highly sulfated glycosaminoglycan,that is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. Heparin significantly inhibits exosome-cell interactions.
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5
5 Cited Publications
Cat. No.: HY-P701242
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2; FGF2; FGFB
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4
4 Cited Publications
Cat. No.: HY-114299
CAS No.: 203787-91-1
Purity:  99.94%
Synonyms: SNAC
Research Areas:  

Others

Salcaprozate sodium (SNAC), an oral absorption promoter, and has the potential as a delivery agent for oral forms of heparin and insulin. Salcaprozate sodium could increase passive transcellular permeation across small intestinal epithelia based on increased lipophilicity arising from non-covalent macromolecule complexation .
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4
4 Cited Publications
Cat. No.: HY-12974
CAS No.: 1194961-19-7
Purity:  98.98%
Synonyms: PRT318
Target:  

Syk Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

PRT-060318 (PRT318) s a potent, selective and orally active tyrosine kinase Syk inhibitor with an IC50 of 3 nM. PRT-060318 suppresses chronic lymphocytic leukemia (CLL) B cell activation and migration, and induces apoptosis. PRT-060318 prevents Heparin (HY-17567)-induced thrombocytopenia and thrombosis in a transgenic mouse model. PRT-060318 dihydrochloride can be used for CLL and thrombus research .
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4
4 Cited Publications
Cat. No.: HY-12974A
CAS No.: 3032567-93-1
Synonyms: PRT318 dihydrochloride
Target:  

Syk Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

PRT-060318 (PRT318) dihydrochloride is a potent, selective and orally active tyrosine kinase Syk inhibitor with an IC50 of 3 nM. PRT-060318 dihydrochloride suppresses chronic lymphocytic leukemia (CLL) B cell activation and migration, and induces apoptosis. PRT-060318 dihydrochloride prevents Heparin (HY-17567)-induced thrombocytopenia and thrombosis in a transgenic mouse model. PRT-060318 dihydrochloride can be used for CLL and thrombus research .
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4
4 Cited Publications
Cat. No.: HY-P70597
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Fibroblast growth factor 7; FGF-7; Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor; FGF7; KGF
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3
3 Cited Publications
Cat. No.: HY-17567C
CAS No.: 9041-08-1
Synonyms: Sodium Heparin (MW 15kDa); Sodium Heparinate (MW 15kDa)
Research Areas:  

Cardiovascular Disease

Heparin sodium salt (MW 15kDa) (Sodium heparin (MW 15kDa)) is a polymer of Heparin with the molecular weight of 15kDa. Heparin sodium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa .
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3
3 Cited Publications
Cat. No.: HY-107911
CAS No.: 9009-65-8
Purity:  99.99%
Target:  

Thrombin

Research Areas:  

Metabolic Disease

Protamine sulfate, polycationic peptide and a antiheparin agent, could neutralize the anticoagulant action of heparin and enhances lipid-mediated gene transfer .
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3
3 Cited Publications
Cat. No.: HY-17567B
CAS No.: 9045-22-1
Heparin Lithium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII). Heparin Lithium salt significantly inhibits exosome-cell interactions.
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3
3 Cited Publications
Cat. No.: HY-P70533
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Fibroblast growth factor 8; Androgen-induced growth factor; Heparin-binding growth factor 8; AIGF; HBGF-8; FGF-8B
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2
2 Cited Publications
Cat. No.: HY-P71213
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Pleiotrophin; PTN; Heparin-binding brain mitogen; HBBM; Heparin-binding growth factor 8; HBGF-8; Osteoblast-specific factor 1; OSF-1;
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2
2 Cited Publications
Cat. No.: HY-P700479
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Fibroblast Growth Factor 2; FGF-2; Basic Fibroblast Growth Factor; bFGF; Heparin-Binding Growth Factor 2; HBGF-2; Fgf2; Fgf-2
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2
2 Cited Publications
Cat. No.: HY-P700289
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Fibroblast Growth Factor 1; FGF-1; Acidic Fibroblast Growth Factor; aFGF; Endothelial Cell Growth Factor; ECGF; Heparin-Binding Growth Factor 1; HBGF-1; FGF1; FGFA
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1
1 Cited Publications
Cat. No.: HY-109509
CAS No.: 679809-58-6
Synonyms: PK 10169; Enoxaparin sodium
Enoxaparin (PK 10169), a low-molecular-weight heparin (LMWH) derivative. Enoxaparin exerts anticoagulant activity through antithrombin III, an endogenous inhibitor of factor Xa and thrombin IIa. Enoxaparin protect the rat hippocampus against TBI (traumatic brain injury) via antioxidant and anti-inflammatory properties. Enoxaparin can be used for the research of deep vein thrombosis (DVT), pulmonary embolism, TBI and COVID-19 .
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1
1 Cited Publications
Cat. No.: HY-N8278
CAS No.: 54328-33-5
Dermatan sulphate sodium is an oral active glycosaminoglycan and thrombin inactivator with antithrombotic activity. It selectively catalyzes the heparin cofactor II-mediated inactivation of thrombin without interacting with antithrombin III. Dermatan sulphate sodium promotes stem cell differentiation, exhibits high bioavailability, and alleviates pulmonary fibrosis injury induced by Bleomycin (HY-108345). Dermatan sulphate sodium can be used in research related to cardiovascular diseases, inflammation, and stem cell differentiation .
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1
1 Cited Publications
Cat. No.: HY-103076
CAS No.: 1016456-76-0
Purity:  97.21%
Target:  

Apolipoprotein

Research Areas:  

Neurological Disease

EZ-482, a novel ligand of apolipoprotein (apoE), binds to sites on apoE in the C-terminal domain with Kds of 5-10 μM for apoE3 and apoE4. EZ-482 binds to apoE4 by a unique N-terminal allosteric effect. EZ482 has the potential for Alzheimer’s diseas .
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1
1 Cited Publications
Cat. No.: HY-P2975
CAS No.: 114956-81-9
Synonyms: Mouse laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane)
Laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane) is a crucial structural element in animal tissues, forming part of the scaffolding that supports tissue architecture. It interacts with type IV collagen through entactin and perlecan, connects to cell membranes via integrin receptors, dystroglycan complexes, and Lutheran blood group glycoproteins, and contains functional domains that facilitate collagen binding, cell adhesion, heparin interaction, and promote neurite outgrowth.
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1
1 Cited Publications
Cat. No.: HY-P10710A
BMP-4 (15-24) acetate is a cell-penetrating heparin-binding peptide with the sequence RKKNPNCRRH. BMP-4 (15-24) acetate exhibits anti-inflammatory and anti-chondrogenic activities. BMP-4 (15-24) acetate can be used in the research of arthritis .
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1
1 Cited Publications
Cat. No.: HY-123275
CAS No.: 64815-81-2
Synonyms: S-2238
Target:  

Thrombin

Research Areas:  

Others

H-D-Phe-Pip-Arg-pNA (S-2238) is a specific chromogenic peptide substrate for thrombin (Thrombin). The amide bond of H-D-Phe-Pip-Arg-pNA is rapidly hydrolyzed by thrombin, producing a characteristic yellow absorbance at 405 nm, and the change in absorbance is proportional to thrombin activity. H-D-Phe-Pip-Arg-pNA can be used in biochemical detection-related studies .
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