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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
45 Results for "
Hydroxyproline
" in MedChemExpress (MCE) Product Catalog:
Products (45)
45 Results for "Hydroxyproline" in MCE Product Catalog:
16
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
2
2 Cited Publications
Synonyms: (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid
Category:
Alkaloids Immune System Disorder Pyrrole Alkaloids Other Diseases Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields
Target:
1
Category:
Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
1
1 Cited Publications
Category:
Natural Products Animals Marine natural products Other marine organisms Disease Research Fields Cancer
Target:
1
1 Cited Publications
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
N-Propargylglycine is a brain-penetrant and orally active PRODH inhibitor. N-Propargylglycine covalently modifies enzyme-bound FAD and active site lysine, causing enzyme structural distortion, protein decay, and irreversible inhibition of proline and 4-hydroxyproline catabolism. N-Propargylglycine induces UPRmt, upregulates mitochondrial chaperones and YME1L1, enhances mitochondrial proteostasis, blocks astrocytic L-proline consumption, and abolishes L-proline’s ATP-maintaining and viability-protective effects. N-Propargylglycine stimulates neural processes, increases brain proline, hydroxyproline, and sarcosine levels, partially normalizes Huntington’s disease whole brain transcriptomes. N-Propargylglycine reduces hyperoxaluria, prevents calcium oxalate stone formation, reduces kidney tubular damage, and restores weight and survival in Grhpr knockout mice. N-Propargylglycine can be used for the research of breast cancer, neurodegenerative disorders, Huntington’s disease, and primary hyperoxaluria type 2 .
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Research Areas:
Cat. No.: HY-40135S
CAS No.: 1356016-86-8
Cat. No.: HY-W337672
CAS No.: 18684-24-7
Synonyms: ProlylHydroxyproline; Pro-Hyp
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Research Areas:
Cat. No.: HY-W129161
CAS No.: 827306-88-7
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Cat. No.: HY-W654232
CAS No.: 2734920-51-3
Synonyms: (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid-d4
Synonyms: SCH-10304
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Research Areas:
Clonixin (SCH-10304) is an orally active non-steroidal anti-inflammatory agent (NSAID) that inhibits COX synthesis. Clonixin acts as a voltage-gated L-type calcium channel blocker, exerts vasodilatory effects by antagonizing Ca 2+ in vascular smooth muscle. Clonixin inhibits TGF-β, reduces lung coefficient, immune cell infiltration level, oxidative stress response, airway resistance, hydroxyproline content and collagen deposition. Clonixin can be used in research related to inflammation such as idiopathic pulmonary fibrosis and moderate to severe pain .
Cat. No.: HY-P10447
CAS No.: 103651-09-8
Synonyms: Fengycin IX; SNA-60-367-3
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Research Areas:
Synonyms: (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid (Standard)
Cat. No.: HY-W008205
CAS No.: 88050-17-3
Synonyms: Fmoc-L-Hydroxyproline
Cat. No.: HY-148231
CAS No.: 58255-46-2
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Research Areas:
Dideoxy-amanitin (compound 2), an α-Amanitin (HY-19610) derivative, is a potent and selective RNA polymerase II allosteric inhibitor with an IC50 value of 74.2 nM .
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Cat. No.: HY-W343900
CAS No.: 6912-67-0
Synonyms: DL-Hydroxyproline
Target:
Research Areas:
Hydroxyproline (DL-Hydroxyproline) is a non-essential amino acid and one of the main components of collagen tissue. Hydroxyproline can be used in research on endocrine and metabolic diseases, as well as genetic diseases and malformations. Hydroxyproline can also serve as a biomarker .
Cat. No.: HY-P4755
CAS No.: 282726-24-3
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
