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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
44 Results for "
IIb/IIIa
" in MedChemExpress (MCE) Product Catalog:
Products (44)
44 Results for "IIb/IIIa" in MCE Product Catalog:
9
9 Publications Verification
Referencia número: HY-B0686
No. CAS: 188627-80-7
Target:
Áreas de investigación:
9
9 Publications Verification
Referencia número: HY-B0686B
No. CAS: 881997-86-0
Target:
Áreas de investigación:
6
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Áreas de investigación:
Tirofiban (L700462) is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area .
6
6 Cited Publications
Referencia número: HY-17369
No. CAS: 150915-40-5
Synonyms: L700462 hydrochloride monohydrate; MK383 hydrochloride monohydrate
Target:
Áreas de investigación:
Tirofiban (L700462) hydrochloride monohydrate is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban hydrochloride monohydrate induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban hydrochloride monohydrate can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area .
3
3 Cited Publications
Referencia número: HY-P0074
No. CAS: 67869-62-9
Synonyms: Gly-Pro-Arg-Pro; Pefa 6003
Target:
Áreas de investigación:
3
3 Cited Publications
Referencia número: HY-P0074A
No. CAS: 157009-81-9
Synonyms: Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate
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Áreas de investigación:
2
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Referencia número: HY-P1507
No. CAS: 89105-94-2
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Áreas de investigación:
Referencia número: HY-146332
No. CAS: 104260-73-3
Target:
Áreas de investigación:
Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research .
Referencia número: HY-B0686A
No. CAS: 1248559-53-6
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Referencia número: HY-10305
No. CAS: 149820-74-6
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Áreas de investigación:
Xemilofiban is an orally active glycoprotein IIb/IIIa blocking agent. Xemilofiban inhibits platelet aggregation. Xemilofiban reduces the incidence of thrombosis .
Referencia número: HY-17369A
No. CAS: 142373-60-2
Synonyms: L700462 hydrochloride; MK383 hydrochloride
Target:
Áreas de investigación:
Tirofiban (L700462) hydrochloride is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban hydrochloride induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban hydrochloride can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area .
Referencia número: HY-17369BR
No. CAS: 144494-65-5
Synonyms: L700462 (Standard); MK383 (Standard)
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Áreas de investigación:
Tirofiban (Standard) is the analytical standard of Tirofiban. This product is intended for research and analytical applications. Tirofiban (L700462) is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area .
Referencia número: HY-101720
No. CAS: 148396-36-5
Synonyms: BIBU-52
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Áreas de investigación:
Fradafiban is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM.
Referencia número: HY-101720A
Pureza: 99.96%
Synonyms: BIBU-52 hydrochloride
Target:
Áreas de investigación:
Fradafiban (BIBU-52) hydrochloride is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM.
Referencia número: HY-10308
No. CAS: 149503-79-7
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Áreas de investigación:
Lefradafiban is an orally active glycoprotein IIb/IIIa receptor antagonist. Lefradafiban can be metabolized to its active form, Fradafiban, a non-peptide GP IIb/IIIa receptor antagonist .
Referencia número: HY-10313
No. CAS: 185836-64-0
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Áreas de investigación:
ZD 2486 is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist. ZD 2486 inhibits platelet aggregation by blocking the binding of fibrinogen to the GP IIb/IIIa receptor on platelets. ZD 2486 can be used for the study of conditions related to unwanted platelet aggregation, such as acute coronary syndrome, unstable angina pectoris, acute myocardial infarction, and complications from cardiovascular interventional procedures [1]
Referencia número: HY-U00235
No. CAS: 180144-61-0
Target:
Áreas de investigación:
SR121566A is a novel non-peptide Glycoprotein IIb/IIIa (GP IIb-IIIa) antagonist, which can inhibit ADP-, arachidonic acid- and collagen-induced human platelet aggregation with IC50s of 46±7.5, 56±6 and 42±3 nM, respectively.
Referencia número: HY-119238
No. CAS: 256385-24-7
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Áreas de investigación:
CRL-42872 is an orally active, highly bioavailable Gp IIb/IIIa platelet receptor inhibitor. CRL-42872 inhibits the binding of fibrinogen to the Gp IIb/IIIa receptor, thereby suppressing collagen-induced platelet aggregation. CRL-42872 is widely used in thrombosis-related studies .
Referencia número: HY-10307
No. CAS: 170902-47-3
Target:
Áreas de investigación:
Roxifiban is a platelet glycoprotein (GP) IIb/IIIa receptor inhibitor that can be used in the study of angina .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
