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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
Inflammasome inhibition
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "Inflammasome inhibition" in MCE Product Catalog:
74
74 Publications Verification
Synonyms: C.I. 75535; Isoarnebin 4
7
7 Cited Publications
Synonyms: Methylmaleic acid; Citraconate
4
3
3 Cited Publications
Synonyms: L-Ascorbic acid 6-hexadecanoate; 6-O-Palmitoyl-L-ascorbic acid
Cat. No.: HY-16059
CAS No.: 84692-91-1
Synonyms: (+)-Arglabin
Category:
Triterpenes Terpenoids Leguminosae Extract Plants Disease Research Fields Inflammation/Immunology Glycine soja Sieb. Et Zucc.
Target:
Synonyms: NLRP3-IN-19 sodium
Target:
Research Areas:
JT001 (NLRP3-IN-19) sodium is a potent, specific and orally active inhibitor of NLRP3. JT001 sodium can inhibit NLRP3 inflammasome assembly, resulting in the inhibition of cytokine release and the prevention of pyroptosis. JT001 sodium can be used for the research of nonalcoholic steatohepatitis and liver fibrosis .
Cat. No.: HY-156034
CAS No.: 2238819-65-1
Synonyms: NLRP3-IN-19
Target:
Research Areas:
JT001 (NLRP3-IN-19) is a potent, specific and orally active inhibitor of NLRP3. JT001 can inhibit NLRP3 inflammasome assembly, resulting in the inhibition of cytokine release and the prevention of pyroptosis. JT001 can be used for the research of nonalcoholic steatohepatitis and liver fibrosis .
Cat. No.: HY-169227
Target:
Research Areas:
NLRP3-IN-55 (Compound 19) is a potent NLRP3 inhibitor (IC50 = 0.34 μM). NLRP3-IN-55 directly targets the NLRP3 protein (KD = 0.45 μM), blocking the assembly and activation of the NLRP3 inflammasome, leading to anti-inflammatory effects and inhibition of cellular pyroptosis .
Cat. No.: HY-W016586R
CAS No.: 42228-92-2
Synonyms: AT-125 (Standard); U-42126 (Standard)
Category:
Cat. No.: HY-113298R
CAS No.: 498-23-7
Synonyms: Methylmaleic acid (Standard); Citraconate (Standard)
Cat. No.: HY-186072
CAS No.: 2771019-10-2
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
NT-0527 is a selective, orally active, and brain-permeable NLRP3 inflammasome inhibitor. NT-0527 can specifically block the formation of the NLRP3 inflammasome, resulting in the reduction in the maturation and release of IL-1β, exhibit inhibition on CYP2C19. NT-0527 displays anti-inflammatory activity in the mouse LPS (HY-D1056) /ATP (HY-B2176)-induced peritonitis model. NT-0527 can be used for the research of neuroinflammatory disorders (Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis) and peripheral inflammatory disorders (type II diabetes, atherosclerosis, gout, etc.) associated with NLRP3 inflammasome .
Cat. No.: HY-16059R
CAS No.: 84692-91-1
Synonyms: (+)-Arglabin (Standard)
Cat. No.: HY-178898
CAS No.: 13072-74-7
Cat. No.: HY-N21694
CAS No.: 303084-57-3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
