33 Results for "

LPC

" in MedChemExpress (MCE) Product Catalog:
Products (33)

33 Results for "LPC" in MCE Product Catalog:

135
135 Publications Verification
Cat. No.: HY-P1410
CAS No.: 1209500-46-8
GsMTx4 is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology .
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135
135 Publications Verification
Cat. No.: HY-P1410A
GsMTx4 TFA is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 TFA also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 TFA is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology .
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3
3 Cited Publications
Cat. No.: HY-P7515
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANXA2; Annexin-2; Prev. ANX2L4; PAP-IV; Prev. CAL1H; P36; Prev. LPC2D; Epididymis Secretory Sperm Binding Protein; Prev. ANX2; Epididymis Secretory Protein Li 270; Annexin II; Calpactin I Heavy Polypeptide; LIP2; Chromobindin 8; Placental Anticoagulant Pr
Species:  
Human
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P7512
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANXA1; Annexin-1; Prev. ANX1; Annexin I (Lipocortin I); Prev. LPC1; ANXA1 Protein; Phospholipase A2 Inhibitory Protein; Lipocortin I; Chromobindin-9; Annexin I; Calpactin II; Annexin; Calpactin-2; P35; Annexin A1; Epididymis Secretory Sperm Binding Protein
Species:  
Human
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P72078
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ANXA1; Annexin-1; Prev. ANX1; Annexin I (Lipocortin I); Prev. LPC1; ANXA1 Protein; Phospholipase A2 Inhibitory Protein; Lipocortin I; Chromobindin-9; Annexin I; Calpactin II; Annexin; Calpactin-2; P35; Annexin A1; Epididymis Secretory Sperm Binding Protei
Species:  
Mouse
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-125771
CAS No.: 19420-57-6
Purity:  99.53%
Synonyms: 18:0 Lyso-PC; LPC(18:0)
1-Stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine that inhibits HDAC3 activity and phosphorylation of STAT3 in K562 cells. 1-Stearoyl-sn-glycero-3-phosphocholine induces apoptosis and exhibits anticancer activity in chronic myelogenous leukemia (CML) K562 cells .
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1
1 Cited Publications
Cat. No.: HY-P71145
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRDX6; PRX; Peroxiredoxin 6; P29; AiPLA2; Red Blood Cells Page Spot 12; NSGPx; Lyso-PC Acyltransferase 5; AOP2; LPC Acyltransferase 5; Acidic Calcium-Independent Phospholipase A2; Antioxidant Protein 2; Lysophosphatidylcholine Acyltransferase 5; Liver 2D
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P77561
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ANXA2; Annexin-2; Prev. ANX2L4; PAP-IV; Prev. CAL1H; P36; Prev. LPC2D; Epididymis Secretory Sperm Binding Protein; Prev. ANX2; Epididymis Secretory Protein Li 270; Annexin II; Calpactin I Heavy Polypeptide; LIP2; Chromobindin 8; Placental Anticoagulant Pr
Species:  
Mouse
Source:  
E. coli
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Cat. No.: HY-N9410
CAS No.: 22252-07-9
Synonyms: 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC; LPC(18:2/0:0); LysoPC(18:2)
Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC), a lysophospholipid, is a potential biomarker identified from insulin resistance (IR) polycystic ovary syndrome (PCOS). Low plasma Lysophosphatidylcholine 18:2 also has been shown to predict impaired glucose tolerance, insulin resistance, type 2 diabetes, coronary artery disease, and memory impairment .
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Cat. No.: HY-145561
CAS No.: 1782070-21-6
Purity:  98.04%
Synonyms: BLD-0409; PAT-409
Cudetaxestat (BLD-0409; PAT-409) is an orally active and noncompetitive autotaxin (ATX) inhibitor. Cudetaxestat inhibits the activity of ATX, reduces the production of LPA, and thereby blocks the signal transduction of the ATX-LPA axis. Cudetaxestat can still maintain nanomolar-level biochemical efficacy even when the concentration of the LPC substrate increases. Cudetaxestat can be used for the study of various diseases related to LPA including fibrosis, tumor metastasis, inflammation and autoimmune diseases, etc .
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Cat. No.: HY-157700
CAS No.: 97802-53-4
Synonyms: C16(Plasm) LPC; Lysophosphatidylcholine 16:0p/0:0
Research Areas:  

Neurological Disease

Hexadecenyl-2-hydroxy-sn-glycero-3-PC (C16(Plasm) LPC) is a phosphatidylcholine. Hexadecenyl-2-hydroxy-sn-glycero-3-PC prolongs the lag-phase of α-syn aggregation, and can be used in Parkinson’s disease research .
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Cat. No.: HY-W020809
CAS No.: 97802-55-6
Synonyms: PC(18:1p/0:0)
Target:  

Endogenous Metabolite

Research Areas:  

Others

C18(Plasm) LPC (PC(18:1p/0:0)) is classified as a type of plasmalogen.
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Cat. No.: HY-126233
CAS No.: 1689554-51-5
Research Areas:  

Others

PAT-347 is an inhibitor of autotaxin (ATX, ENPP-2) . PAT-347 binds only to the hydrophobic channel of ATX, without occupying its hydrophobic pocket and catalytic site . PAT-347 blocks the binding of lysophosphatidylcholine (LPC) to the catalytic site of ATX .
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Cat. No.: HY-125771S
CAS No.: 327178-92-7
Synonyms: 18:0 Lyso-PC-d35; LPC(18:0)-d35
1-Stearoyl-sn-glycero-3-phosphocholine-d35 is deuterium labeled 1-Stearoyl-sn-glycero-3-phosphocholine (HY-125771). 1-Stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine that inhibits HDAC3 activity and phosphorylation of STAT3 in K562 cells. 1-Stearoyl-sn-glycero-3-phosphocholine induces apoptosis and exhibits anticancer activity in chronic myelogenous leukemia (CML) K562 cells .
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Cat. No.: HY-173509
CAS No.: 2023027-81-6
ATX inhibitor 27 (Compound 31) is an ATX inhibitor. The IC50 values of ATX inhibitor 27 against human autotaxin (hATX) and lysophosphatidylcholine (LPC) are 13 nM and 23 nM, respectively. ATX inhibitor 27 reduces LPA levels in vivo by inhibiting ATX enzyme. ATX inhibitor 27 can be used in the study of ATX-LPA-related diseases such as inflammation, neurodegenerative diseases and cancer .
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Cat. No.: HY-RS10176
Research Areas:  

Others

PCSK7 Human Pre-designed siRNA Set A contains three designed siRNAs for PCSK7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-149716
CAS No.: 3047891-88-0
Research Areas:  

Cancer

MEY-003 is an Autotaxin(ATX) inhibitor with EC50s of 460 nM and 1.09 μM for hATX-β and hATX-ɣ (analysis with LPC18:1). MEY-003 behaves as a non-competitive inhibitor with K iof 432 nM. MEY-003 can be used for targeted ATX-related disease research .
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Cat. No.: HY-134954
CAS No.: 910228-13-6
Research Areas:  

Cancer

Palmitoleoyl 3-carbacyclic phosphatidic acid (3ccPA 16:1) is an intermediately potent inhibitor of autotaxin (ATX) with an IC50 of 620 nM. Palmitoleoyl 3-carbacyclic phosphatidic acid can be used for melanoma research .
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Cat. No.: HY-160581
CAS No.: 496801-51-5
Target:  

Liposome

Research Areas:  

Others

OH-C-Chol is a cationic liposome that serves as a siRNA delivery vehicle. OH-C-Chol (LP-C) and OH-NC-Chol (LP-NC)/siRNA complexes (lipoplexes) showed better performance than NP-C and NP-NC/siRNA complexes (nanocomplexes), respectively. ) greater gene silencing effect .
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Cat. No.: HY-120633
CAS No.: 1622180-31-7
Target:  

LPL Receptor

BMS-986104 is a potent and selective S1P1 receptor modulator. BMS-986104 is effective in a mouse EAE model, which is comparable to FTY720. Mechanistically, BMS-986104 exhibites excellent remyelinating effects on lysophosphatidylcholine (LPC)-induced demyelination in a three-dimensional brain cell culture assay.
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