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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
160 Results for "
MM
" in MedChemExpress (MCE) Product Catalog:
Products (160)
160 Results for "MM" in MCE Product Catalog:
174
174 Publications Verification
Synonyms: Adenosine 5'-triphosphate disodium salt, 100 MM Solution, PCR Grade
Áreas de investigación:
ATP (Adenosine 5'-triphosphate) disodium salt, 100 mM Solution, PCR Grade is a central component of energy storage and metabolism in vivo. ATP disodium salt, 100 mM Solution, PCR Grade provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt, 100 mM Solution, PCR Grade is an important endogenous signaling molecule in immunity and inflammation. ATP disodium salt, 100 mM Solution, PCR Grade can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP disodium salt, 100 mM Solution, PCR Grade has anti-bacterial infection effects and can protect mice against bacterial infection in mice .
The product specifications provided below indicate the total amount only; they do not represent the actual content of ATP disodium salt.
The product specifications provided below indicate the total amount only; they do not represent the actual content of ATP disodium salt.
4
4 Cited Publications
Synonyms: HMTase Inhibitor IX
Áreas de investigación:
MM-102 (HMTase Inhibitor IX) is a cell-permeable and tightly binding inhibitor of MLL1-WDR5 interaction (IC50=2.4 nM). MM-102 can specifically inhibit the growth and induce apoptosis of leukemia cells containing MLL1 fusion protein, and reduce renal fibrosis and inflammation in mice with ischemia-reperfusion injury. In addition, MM-102 also acts as an H3K4 histone methyltransferase inhibitor to improve the development of porcine somatic cell nuclear transfer (SCNT) embryos .
4
4 Cited Publications
Referencia número: HY-113225H
No. CAS: 36051-31-7
Synonyms: Guanosine triphosphate trisodium salt, 100 MM Solution, PCR Grade
Target:
Áreas de investigación:
GTP trisodium salt, 100 mM Solution, PCR Grade (Guanosine triphosphate trisodium salt, 100 mM Solution, PCR Grade) is a solution prepared from GTP at a concentration of 100 mM, free of DNase, RNase and phosphatase contamination, and suitable for molecular biology research .
The product specifications provided below indicate the total amount only; they do not represent the actual content of GTP trisodium salt.
The product specifications provided below indicate the total amount only; they do not represent the actual content of GTP trisodium salt.
4
4 Cited Publications
Synonyms: HMTase Inhibitor IX TFA
MM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM with an estimated Ki < 1 nM in WDR5 binding assay, which is >200 times more potent than the ARA peptide.
3
3 Cited Publications
Referencia número: HY-113225B
No. CAS: 103192-46-7
Synonyms: GTP tritris solution (100 MM)
Áreas de investigación:
Guanosine triphosphate (GTP) tritris solution (100 mM) is a critical nucleotide and regulator of cellular metabolism. Guanosine triphosphate tritris solution (100 mM) promotes ribosomal DNA localization, pre-rRNA transcription and ribosome biogenesis by binding to RNA polymerase I and GPN proteins (GPN1/3). Guanosine triphosphate tritris solution (100 mM) links MYC-dependent ribosome biogenesis to nucleotide sufficiency, acts as a metabolic gatekeeper supporting protein synthesis, DNA/RNA synthesis and cellular signal transduction, while also participating in the physiological activities of pancreatic β-cells and serving as an oxidative substrate for reactive oxygen species. In small cell lung cancer with high MYC expression, Guanosine triphosphate tritris solution (100 mM) accumulates through the IMPDH-driven synthetic pathway, thereby affecting apoptosis and mitotic processes. Guanosine triphosphate tritris solution (100 mM) is used in the research of small cell lung cancer, hepatoblastoma and cellular metabolism .
The product specifications provided below indicate the total amount only; they do not represent the actual content of Guanosine triphosphate tritris.
The product specifications provided below indicate the total amount only; they do not represent the actual content of Guanosine triphosphate tritris.
1
1 Cited Publications
Synonyms: ac4CTP sodium solution (100MM)
Target:
Áreas de investigación:
N4-Acetylcytidine triphosphate sodium solution (100mM) is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro
transcription and it can be incorporated into multiple templates .
The product specifications provided below indicate the total amount only; they do not represent the actual content of N4-Acetylcytidine triphosphate sodium.
The product specifications provided below indicate the total amount only; they do not represent the actual content of N4-Acetylcytidine triphosphate sodium.
1
1 Cited Publications
Referencia número: HY-W096178B
No. CAS: 14808-60-7
Target:
Áreas de investigación:
Silica sand, 1-2 mm is an inorganic, inert, and biocompatible (under certain conditions) solid matrix composed of high-purity silica particles. Silica sand, 1-2 mm is primarily used as a physical functional material in biochemical research .
1
1 Cited Publications
Synonyms: dCTP trisodium solution (100 MM); 2′-Deoxycytidine-5′-triphosphate trisodium solution (100 MM)
The product specifications provided below refer solely to the active content of Deoxycytidine triphosphate trisodium.
1
1 Cited Publications
Referencia número: HY-W008661
No. CAS: 93919-41-6
Synonyms: dGTP trisodium solution (100 MM); 2'-Deoxyguanosine-5'-triphosphate trisodium solution (100 MM)
Target:
Áreas de investigación:
Deoxyguanosine triphosphate (dGTP) trisodium solution (100 mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification .
The product specifications provided below refer solely to the active content of Deoxyguanosine triphosphate trisodium.
The product specifications provided below refer solely to the active content of Deoxyguanosine triphosphate trisodium.
1
1 Cited Publications
Referencia número: HY-141567A
Pureza: ≥98.0%
Synonyms: Pseudo-UTP trisodium solution (100 MM)
Target:
Áreas de investigación:
Pseudouridine 5'-triphosphate (Pseudo-UTP) trisodium solution (100 mM) is a modified ribonucleoside triphosphate and uracil base-modified UTP derivative. Pseudouridine 5'-triphosphate trisodium solution (100 mM) enhances translational properties and stability of mRNA, reduces innate immune responses in mammalian cells, and inhibits signal-dependent transcription termination of vaccinia virus early gene transcription while supporting transcription elongation. Pseudouridine 5'-triphosphate trisodium solution (100 mM) can be used for the research of vaccinia virus infection .
The product specifications provided below indicate the total amount only; they do not represent the actual content of Pseudouridine 5'-triphosphate trisodium.
The product specifications provided below indicate the total amount only; they do not represent the actual content of Pseudouridine 5'-triphosphate trisodium.
1
Áreas de investigación:
5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium) is a modified cytidine triphosphate nucleotide. 5-Methylcytidine 5′-triphosphate trisodium serves as a modified nucleotide substrate for in vitro transcription, partially or completely replacing CTP. 5-Methylcytidine 5′-triphosphate trisodium enhances mRNA stability and translation efficiency, and reduces activation of the innate immune system. 5-Methylcytidine 5′-triphosphate trisodium is used in RNA synthesis-related research .
The product specifications provided below refer solely to the active content of 5-Methylcytidine 5′-triphosphate trisodium.
The product specifications provided below refer solely to the active content of 5-Methylcytidine 5′-triphosphate trisodium.
1
1 Cited Publications
MM3122 is a selective type II transmembrane serine protease (TMPRSS2) inhibitor with an IC50 value of 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry of SARS-CoV-2 and MERS-CoV into human cells .
1
1 Cited Publications
Referencia número: HY-19554A
No. CAS: 1442106-11-7
MM-401 (TFA) is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity (IC50 = 0.32 μM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia .
1
1 Cited Publications
Referencia número: HY-154909A
Pureza: ≥98.0%
Synonyms: 6-Azauridine 5′-triphosphate aMMonium solution (100 MM ± 3 MM)
Target:
Áreas de investigación:
6-Azauridine triphosphate (6-Azauridine 5′-triphosphate) ammonium solution (100 mM ± 3 mM) is a uridine triphosphate analog nucleotide and a triphosphate metabolite formed from 6-Azuridine (AzUrd) (HY-131611) in L1210 cells, acting as a substrate analog of RNA polymerase. 6-Azauridine triphosphate ammonium solution (100 mM ± 3 mM) can be used in the study of leukemia .
The product specifications provided below indicate the total amount only; they do not represent the actual content of 6-Azauridine triphosphate ammonium.
The product specifications provided below indicate the total amount only; they do not represent the actual content of 6-Azauridine triphosphate ammonium.
1
1 Cited Publications
Referencia número: HY-128788A
Áreas de investigación:
ddhCTP trisodium solution (100 mM ± 3 mM) is an endogenously produced pyrimidine base analog with a Kd of 17.0 nM for LLDH and an IC50 of 55.8 μM for GAPDH. By inhibiting key metabolic enzymes such as GAPDH, ddhCTP trisodium reduces glycolytic flux and shifts metabolic flow toward the pentose phosphate pathway, thereby regulating the redox balance of cells. As a competitive CTP analog, ddhCTP trisodium terminates RNA synthesis by flavivirus RdRps and SARS-CoV-2 RdRp, and inhibits Zika virus replication in vivo. ddhCTP trisodium can be used in studies related to viral infections, COVID-19 and Zika virus infections .
The product specifications provided below indicate the total amount only; they do not represent the actual content of ddhCTP trisodium.
The product specifications provided below indicate the total amount only; they do not represent the actual content of ddhCTP trisodium.
1
1 Cited Publications
Referencia número: HY-155878A
No. CAS: 1630828-71-5
Áreas de investigación:
5-Fluoro-2′-deoxy-UTP sodium can be used as a substrate for DNA synthesis .
The product specifications provided below indicate the total amount only; they do not represent the actual content of 5-Fluoro-2′-deoxy-UTP.
The product specifications provided below indicate the total amount only; they do not represent the actual content of 5-Fluoro-2′-deoxy-UTP.
1
1 Cited Publications
Synonyms: 2',3'-Dideoxyadenosine 5'-triphosphate trisodium
Target:
Áreas de investigación:
ddATP (2',3'-Dideoxyadenosine 5'-triphosphate) trisodium, an active metabolite of 2',3'-dideoxyinosine, is a chain-elongating inhibitor of DNA polymerase. ddATP trisodium can be used for Sanger method for DNA sequencing and research of virus infection .
The product specifications provided below indicate the total amount only; they do not represent the actual content of ddATP trisodium.
The product specifications provided below indicate the total amount only; they do not represent the actual content of ddATP trisodium.
1
1 Cited Publications
Referencia número: HY-112582A
No. CAS: 1428903-59-6
Synonyms: 1-Methylpseudouridine-5′-triphosphate
Áreas de investigación:
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability.
The product specifications provided below indicate the total amount only; they do not represent the actual content of N1-Methylpseudouridine-5′-triphosphate.
The product specifications provided below indicate the total amount only; they do not represent the actual content of N1-Methylpseudouridine-5′-triphosphate.
1
1 Cited Publications
Synonyms: 1-Methylpseudouridine-5′-triphosphate trisodium; N1-Me-Pseudo UTP trisodium; N1-Methyl-Pseudo-UTP trisodium
Áreas de investigación:
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability .
The product specifications provided below refer solely to the active content of N1-Methylpseudouridine-5′-triphosphate trisodium.
The product specifications provided below refer solely to the active content of N1-Methylpseudouridine-5′-triphosphate trisodium.
1
1 Cited Publications
Referencia número: HY-P700669
Pureza: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD163; MM130; CD163 Molecule; Hemoglobin Scavenger Receptor; M130; CD163 Antigen; Scavenger Receptor Cysteine-Rich Type 1 Protein M130; Macrophage-Associated Antigen; SCARI1
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
