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MM

" in MedChemExpress (MCE) Product Catalog:

136

Inhibitors & Agonists

1

Fluorescent Dye

54

Biochemical Assay Reagents

4

Peptides

14

Inhibitory Antibodies

4

Natural
Products

6

Recombinant Proteins

3

Isotope-Labeled Compounds

8

Antibodies

5

Click Chemistry

20

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y1977

    Biochemical Assay Reagents Others
    100 mM Pro-Ac, 20 mM Arg, pH 5.0 buffer is a buffer solution and can be used as a reconstitution buffer for ADC products.
    100 mM Pro-Ac, 20 mM Arg, pH 5.0 buffer
  • HY-Y1968A

    Sterile 10 MM His-HCl, pH 5.5 buffer

    Biochemical Assay Reagents Others
    Sterile 10 mM Histidine, pH 5.5 buffer is a sterile solution using 10 mM histidine as the solute with its pH adjusted to 5.5, possessing both buffering capacity and biocompatibility. Sterile 10 mM Histidine, pH 5.5 buffer is widely applied in laboratory research, pharmaceutical production, cosmetics and other fields .
    Sterile 10 mM Histidine, pH 5.5 buffer
  • HY-P99394
    Talquetamab
    1 Publications Verification

    JNJ-64407564

    CD3 Cancer
    Talquetamab (JNJ-64407564) is a humanized bispecific antibody that binds to GPRC5D (member of G protein-coupled receptor family C5 group D) and CD3 to induce T cell-mediated killing of GPRC5D-expressing MM cells through T cell recruitment and activation. Talquetamab (JNJ-64407564) has antitumor activity .
    Talquetamab
  • HY-12220
    MM-102
    4 Publications Verification

    HMTase Inhibitor IX

    WDR5 Apoptosis NF-κB TNF Receptor Interleukin Related Inflammation/Immunology Cancer
    MM-102 (HMTase Inhibitor IX) is a cell-permeable and tightly binding inhibitor of MLL1-WDR5 interaction (IC50=2.4 nM). MM-102 can specifically inhibit the growth and induce apoptosis of leukemia cells containing MLL1 fusion protein, and reduce renal fibrosis and inflammation in mice with ischemia-reperfusion injury. In addition, MM-102 also acts as an H3K4 histone methyltransferase inhibitor to improve the development of porcine somatic cell nuclear transfer (SCNT) embryos .
    MM-102
  • HY-150145A

    Nucleoside Antimetabolite/Analog Fluorescent Dye Others
    Cy5-UTP sodium (10 mM in water) is a fluorescently labeled ribonucleotide triphosphate that can be used as a substrate for terminal deoxynucleotide transferase (TdT). Cy5-UTP sodium can be used to label RNA probes generated in vitro (Ex/Em: 650/665 nm). Cy5-UTP sodium can be applied in FISH, multi-color fluorescence analysis, especially in dual-color expression arrays combined with Cy5-UTP .
    Cy5-UTP sodium (10 mM in water)
  • HY-W096178B

    Biochemical Assay Reagents Others
    Silica sand, 1-2 mm is an inorganic, inert, and biocompatible (under certain conditions) solid matrix composed of high-purity silica particles. Silica sand, 1-2 mm is primarily used as a physical functional material in biochemical research .
    Silica sand, 1-2mm
  • HY-158712

    Others
    3'-ONH2-dATP (sodium) solution (100 mM) is a 3'-O-blocked reversible terminator deoxynucleotide triphosphate.3'-ONH2-dATP (sodium) solution (100 mM) stops DNA polymerization after single-nucleotide addition to an initiator strand, and its 3'-ONH2 blocking group can be removed to restore a free 3'-OH for subsequent extension.3'-ONH2-dATP (sodium) solution (100 mM) incorporates into an oligonucleotide chain by engineered terminal deoxynucleotidyl transferase from Zonotrichia albicollis to enable template-free, stepwise de novo enzymatic DNA synthesis .
    3'-ONH2-dATP sodium solution (100 mM)
  • HY-P99268

    SAR 256212; MM 121; Anti-Human ERBB3/ErbB 3 Recombinant Antibody

    EGFR Apoptosis Cancer
    Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models .
    Seribantumab
  • HY-150350

    Biochemical Assay Reagents Others
    The 20 mM HEPES, 150 mM NaCl, 240 mM Sucrose, pH 7.2 buffer is a physiological buffer composed of 20 mM HEPES, 150 mM NaCl and 240 mM Sucrose, adjusted to pH 7.2, which is used to resuspend human erythrocyte ghost preparations .
    20 mM HEPES, 150 mM NaCl, 240 mM Sucrose, pH 7.2 buffer
  • HY-W013715A

    dTTP trisodium solution (100 MM)

    DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite Others
    Deoxythymidine-5'-triphosphate (dTTP) (trisodium) solution (100 mM) is one of the raw materials used by DNA polymerase to synthesize long DNA strands during DNA replication. Deoxythymidine-5'-triphosphate (trisodium) solution (100 mM) is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied as an aqueous solution.
    Deoxythymidine-5'-triphosphate trisodium solution (100 mM)
  • HY-170224

    Biochemical Assay Reagents Others
    dNTP Mixture,10 mM Solution,PCR Grade is a PCR-grade 10 mM mixed solution of natural deoxynucleoside triphosphates (dATP, dCTP, dGTP, TTP), which is suitable for various biological reactions including DNA amplification and reverse transcription .
    dNTP Mixture,10 mM Solution,PCR Grade
  • HY-113225H

    Guanosine triphosphate trisodium salt, 100 MM Solution, PCR Grade

    Biochemical Assay Reagents Cancer
    GTP trisodium salt, 100 mM Solution, PCR Grade (Guanosine triphosphate trisodium salt, 100 mM Solution, PCR Grade) is a solution prepared from GTP at a concentration of 100 mM, free of DNase, RNase and phosphatase contamination, and suitable for molecular biology research .
    GTP trisodium salt, 100 mM Solution, PCR Grade
  • HY-B2176I
    ATP disodium salt, 100 mM Solution, PCR Grade
    Maximum Cited Publications
    143 Publications Verification

    Adenosine 5'-triphosphate disodium salt, 100 MM Solution, PCR Grade

    Endogenous Metabolite NOD-like Receptor (NLR) Interleukin Related Bacterial Infection Metabolic Disease Inflammation/Immunology
    ATP (Adenosine 5'-triphosphate) disodium salt, 100 mM Solution, PCR Grade is a central component of energy storage and metabolism in vivo. ATP disodium salt, 100 mM Solution, PCR Grade provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt, 100 mM Solution, PCR Grade is an important endogenous signaling molecule in immunity and inflammation. ATP disodium salt, 100 mM Solution, PCR Grade can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP disodium salt, 100 mM Solution, PCR Grade has anti-bacterial infection effects and can protect mice against bacterial infection in mice .
    ATP disodium salt, 100 mM Solution, PCR Grade
  • HY-P99672

    MM 141; MM-005

    IGF-1R EGFR Cancer
    Istiratumab (M-6495) is bispecific monoclonal antibody targeting IGF-1R and ErbB3. Istiratumab induces IGF-1R and ErbB3 receptor degradation through the proteasome pathway Istiratumab can be used for research of cancers .
    Istiratumab
  • HY-108003

    Apelin Receptor (APJ) Cardiovascular Disease
    MM 07 is a biased apelin receptor agonist, with a KD of 300 nM in CHO-K1 cells and a KD of 172 nM in human heart.
    MM 07
  • HY-160972

    LXR Neurological Disease Cancer
    MM0299 is a selective lanosterol synthase (LSS) inhibitor with an IC50 value of 2.22 μM. MM0299 depletes intracellular cholesterol and acts as a growth inhibitor for glioma stem-like cells. MM0299 exhibits anti-glioblastoma activity. MM0299 is applicable to research related to glioblastoma .
    MM0299
  • HY-101400A

    dCTP trisodium solution (100 MM); 2′-Deoxycytidine-5′-triphosphate trisodium solution (100 MM)

    DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite Metabolic Disease
    Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100 mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .
    Deoxycytidine triphosphate trisodium solution (100 mM)
  • HY-W008661

    dGTP trisodium solution (100 MM); 2'-Deoxyguanosine-5'-triphosphate trisodium solution (100 MM)

    DNA/RNA Synthesis Others
    Deoxyguanosine triphosphate (dGTP) trisodium solution (100 mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification .
    Deoxyguanosine triphosphate trisodium solution (100 mM)
  • HY-12220A
    MM-102 TFA
    4 Publications Verification

    HMTase Inhibitor IX TFA

    WDR5 Cancer
    MM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM with an estimated Ki < 1 nM in WDR5 binding assay, which is >200 times more potent than the ARA peptide.
    MM-102 TFA
  • HY-141452

    Malondialdehyde

    Endogenous Metabolite Neurological Disease
    Propanedial (Malondialdehyde) (13.88 mM in water) is one of the final products of lipid peroxidation. Propanedial causes protein inactivation, DNA damage and cross-linking by forming stable covalent adducts with biological macromolecules, which is the main mechanism for its cytotoxicity and genotoxicity. Propanedial production increases with the elevation of free radicals. Propanedial is a key biomarker for evaluating the level of cellular oxidative stress [1][2][3].
    Propanedial (13.88 mM in water)
  • HY-P2271

    Apelin Receptor (APJ) Cancer
    MM 54 (compound 5) is a competitive antagonist at APJ, with an IC50 of 93 nM. MM 54 behaves as a potent and selective inhibitor of apelin binding and APLNR activation .
    MM 54
  • HY-108530

    RAR/RXR Cancer
    MM11253 is a potent and selective RARγ antagonist with an IC50 of 44 nM. MM11253 has lower inhibition of RARα, RARβ and RXRα. MM11253 blocks the growth inhibitory effects of RARγ-selective agonists .
    MM11253
  • HY-141567A

    Pseudo-UTP trisodium solution (100 MM)

    DNA/RNA Synthesis Infection
    Pseudouridine 5'-triphosphate (Pseudo-UTP) trisodium solution (100 mM) is a modified ribonucleoside triphosphate and uracil base-modified UTP derivative. Pseudouridine 5'-triphosphate trisodium solution (100 mM) enhances translational properties and stability of mRNA, reduces innate immune responses in mammalian cells, and inhibits signal-dependent transcription termination of vaccinia virus early gene transcription while supporting transcription elongation. Pseudouridine 5'-triphosphate trisodium solution (100 mM) can be used for the research of vaccinia virus infection .
    Pseudouridine 5'-triphosphate trisodium solution (100 mM)
  • HY-147428

    MM-110; (±)​-18-Methoxycoronaridine

    nAChR Parasite Infection Neurological Disease
    Zolunicant (MM-110) is a potent inhibitor against nicotinic α3β4 receptors with an IC50 of 0.90 μM to combat addiction. Zolunicant can decrease the self-administration of several addictive agents including morphine, methamphetamine, nicotine, and ethanol in rat model. Zolunicant can be studied as a potential research for multiple forms of agent abuse . Zolunicant also reveals a potent leishmanicide effect against Leishmania amazonensis .
    Zolunicant
  • HY-137694B

    DNA/RNA Synthesis Others
    ddTTP trisodium solution (100 mM) is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing .
    ddTTP trisodium solution (100 mM)
  • HY-137697D

    HIV DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Drug Metabolite HIV Protease Infection
    ddCTP trilithium solution (100 mM) is a chain-terminating dideoxynucleotide. ddCTP trilithium can be incorporated into an extending primer strand lacking a 3'-hydroxyl group, thereby terminating primer extension, viral genome replication, and DNA synthesis. In primer extension inhibition assays, ddCTP trilithium enables discrimination of nearly identical RNAs via distinguishable extension products.
    ddCTP trisodium solution (100 mM)
  • HY-153108

    ARCA cap solution (100 MM)

    DNA/RNA Synthesis Others
    3'-O-Me-m7G(5')ppp(5')A (ARCA cap) solution (100 mM), anti-reverse cap analog, has a special RNA cap structure. 3'-O-Me-m7G(5')ppp(5')A solution (100 mM) improves mRNA translation efficiency and stability, reduces translational inhibition by proteins such as IFIT1, and enables stronger and longer-lasting expression of the target protein. The RNA cap structure is a common feature of mRNAs in some RNA viruses and eukaryotes, and it serves as a signal for translation initiation .
    3'-O-Me-m7G(5')ppp(5')A solution (100 mM)
  • HY-158715

    Biochemical Assay Reagents DNA/RNA Synthesis Others
    3'-ONH2-dTTP sodium solution (100 mM) is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
    3'-ONH2-dTTP sodium solution (100 mM)
  • HY-125818I

    Cytidine triphosphate disodium salt, 100 MM Solution, PCR Grade; 5'-CTP disodium salt, 100 MM Solution, PCR Grade

    Biochemical Assay Reagents Metabolic Disease
    CTP (Cytidine triphosphate; 5'-CTP disodium salt) disodium salt, 100 mM Solution, PCR Grade is an immediate-use solution of cytidine triphosphate diodium salt. CTP is one of the four basic raw materials for RNA biosynthesis. CTP disodium salt is mainly used in molecular biology applications such as in vitro transcription (IVT), RNA synthesis and labeling .
    CTP disodium salt, 100 mM Solution, PCR Grade
  • HY-146247A

    4'-Fluorouridine TP sodium

    RSV Nucleoside Antimetabolite/Analog Infection
    4'-Fluorouridine triphosphate (4'-Fluorouridine TP) sodium is a bioactive 5’-triphosphate form of 4'-Fluorouridine (EIDD-2749) (HY-146246). 4'-Fluorouridine triphosphate can effectively bind to RSV RdRP .
    4'-Fluorouridine triphosphate sodium solution (100 mM)
  • HY-175783

    Apoptosis Cancer
    MM927 is a potent NVL inhibitor, with an IC50 of 0.053 μM. MM927 blocks 60S ribosomal subunit biogenesis in the nucleolus. MM927 induces half-mer polysomes, cell cycle arrest at G1/S and G2/M and apoptosis in cells. MM927 demonstrates antitumor efficacy in MOLM-13 AML and HCT116 CRC xenograft models. MM927 can be used for the study of cancers such as acute myeloid leukemia (AML) and colorectal cancer (CRC) .
    MM927
  • HY-121725

    STAT Cancer
    MM-206, a STAT3 activity inhibitor, potently inhibits the STAT3 SH2 domain-phosphopeptide interaction with IC50 of 1.2 μM. MM-206 demonstrates dose-dependent induction of apoptosis in acute myeloid leukemia (AML) cell lines .
    MM-206
  • HY-148072

    SARS-CoV Infection
    MM3122 is a selective type II transmembrane serine protease (TMPRSS2) inhibitor with an IC50 value of 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry of SARS-CoV-2 and MERS-CoV into human cells .
    MM3122
  • HY-19554A
    MM-401 TFA
    1 Publications Verification

    WDR5 Apoptosis Cancer
    MM-401 (TFA) is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity (IC50 = 0.32 μM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia .
    MM-401 TFA
  • HY-112581B

    5-Methoxy-UTP trisodium solution (100 MM); 5-OMe-UTP trisodium solution (100 MM)

    DNA/RNA Synthesis Others
    5-Methoxyuridine 5'-triphosphate trisodium solution (100 mM) is a modified nucleotide triphosphate (NTP). 5-Methoxyuridine 5'-triphosphate trisodium can be added into mRNA with T7 RNA polymerase .
    5-Methoxyuridine 5'-triphosphate trisodium solution (100 mM)
  • HY-P99630

    MM-302 antibody

    EGFR Cancer
    Gancotamab antibody (MM-302) is a HER2-targeted antibody with antitumor activity .
    Gancotamab antibody
  • HY-W017068B

    2'-Deoxyuridine-5'-triphosphate trisodium,100 MM Solution,PCR Grade

    Biochemical Assay Reagents Others
    dUTP trisodium,100 mM Solution,PCR Grade (2'-Deoxyuridine-5'-triphosphate trisodium,100 mM Solution,PCR Grade) is a highly stable nucleotide that can participate in the biosynthesis of DNA and is suitable for various conventional molecular biology experiments. This product is provided in the form of aqueous solution .
    dUTP trisodium,100 mM Solution,PCR Grade
  • HY-136648B

    dATP trisodium,100 MM Solution,PCR Grade

    Biochemical Assay Reagents Others
    2'-Deoxyadenosine-5'-triphosphate trisodium,100 mM Solution,PCR Grade (dATP trisodium,100 mM Solution,PCR Grade) is one of the raw materials used by DNA polymerase to synthesize long DNA strands during DNA replication. 2'-Deoxyadenosine-5'-triphosphate trisodium,100 mM Solution,PCR Grade is used in reverse transcription polymerase chain reaction (RT-PCR) for DNA amplification. This product is supplied in the form of an aqueous solution .
    2'-Deoxyadenosine-5'-triphosphate trisodium,100 mM Solution,PCR Grade
  • HY-158674

    Biochemical Assay Reagents DNA/RNA Synthesis Others
    3'-P-dGTP sodium,100 mM Solution is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
    3'-P-dGTP sodium,100 mM Solution
  • HY-158714

    Biochemical Assay Reagents DNA/RNA Synthesis Others
    3'-ONH2-dCTP sodium solution (100 mM) is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
    3'-ONH2-dCTP sodium solution (100 mM)
  • HY-107372H

    Uridine 5'-triphosphate trisodium salt, 100 MM Solution, PCR Grade

    Biochemical Assay Reagents Endogenous Metabolite DNA/RNA Synthesis P2Y Receptor Cardiovascular Disease
    UTP (Uridine 5'-triphosphate) trisodium salt, 100 mM Solution, PCR Grade is a solution prepared from uridine triphosphate at a concentration of 100 mM, free of DNase, RNase and phosphatase contamination, suitable for molecular biology research. Uridine triphosphate (HY-107372) is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate activates membrane-bound P2Y2 receptors .
    UTP trisodium salt, 100 mM Solution, PCR Grade
  • HY-145973A

    m7(3'OMeG)(5')ppp(5')(2'OMeA)pG aMMonium solution (100 MM)

    DNA/RNA Synthesis Others
    3'OMe-m7GpppAmpG ammonium solution (100 mM) is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG ammonium shows a significant translational efficiency. 3'OMe-m7GpppAmpG ammonium can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .
    3'OMe-m7GpppAmpG ammonium solution (100 mM)
  • HY-P3282

    Guanylate Cyclase Metabolic Disease
    MM 419447, a linaclotide metabolite, is a guanylate cyclase-C agonist. MM 419447 has the potential for the research of the irritable bowel syndrome with constipation (IBS-C) .
    MM 419447
  • HY-142028A

    AcycloGTP sodium (100 MM)

    DNA/RNA Synthesis Nucleoside Antimetabolite/Analog HIV Reverse Transcriptase Infection
    Acyclovir triphosphate (Synonyms: AcycloGTP) sodium is a Acyclovir (HY-17422) derivative that competitively inhibits viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). Acyclovir triphosphate (sodium) (100 mM) is an inhibitor of HIV-1 reverse transcriptase. Acyclovir triphosphate (sodium) (100 mM) causes termination of viral DNA synthesis .
    Acyclovir triphosphate sodium (100 mM)
  • HY-16967

    G-quadruplex Bcl-2 Family Ras Caspase Cancer
    MM41 is a quadruplex-interacting compound. MM41 binds tightly to quadruplexes encoded in the promoter sequences of the BCL-2 and k-RAS genes. MM41 reduces BCL-2 and k-RAS protein levels, increases caspase 3. MM41 has antitumor effects against pancreatic cancer .
    MM41
  • HY-19554

    WDR5 Apoptosis Cancer
    MM-401 is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity (IC50 = 0.32 μM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia .
    MM-401
  • HY-161166

    Others Others
    MM-02-57 is a covalent DDB1 CUL4A adaptor protein recruiter .
    MM-02-57
  • HY-134393B

    N6-Methyl-ATP trisodium solution (100 MM)

    GSK-3 Others
    6-Me-ATP (N6-Methyl-ATP) trisodium solution (100 mM) is a N 6-modified ATP derivative. 6-Me-ATP trisodium shows excellent binding affinity to GSK3, serving as the phosphate group donor for GSK3β-catalyzed phosphorylation of its substrate peptide .
    6-Me-ATP trisodium solution (100 mM)
  • HY-W008661A

    dGTP trisodium,100 MM Solution,PCR Grade; 2'-Deoxyguanosine-5'-triphosphate trisodium,100 MM Solution,PCR Grade

    DNA/RNA Synthesis Others
    Deoxyguanosine triphosphate (dGTP) trisodium,100 mM Solution,PCR Grade is one of the raw materials used by DNA polymerases to synthesize long DNA strands during DNA replication. Deoxyguanosine triphosphate trisodium,100 mM Solution,PCR Grade is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied in the form of an aqueous solution .
    Deoxyguanosine triphosphate  trisodium,100 mM Solution,PCR Grade
  • HY-W013715B

    dTTP trisodium,100 MM Solution,PCR Grade

    DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite Others
    Deoxythymidine-5'-triphosphate (dTTP) trisodium, 100 mM Solution, PCR Grade is one of the raw materials used by DNA polymerase to synthesize long DNA strands during DNA replication. Deoxythymidine-5'-triphosphate trisodium, 100 mM Solution, PCR Grade is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied as an aqueous solution.
    Deoxythymidine-5'-triphosphate trisodium,100 mM Solution,PCR Grade

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