1. Cell Cycle/DNA Damage
    Anti-infection
  2. DNA/RNA Synthesis
    HIV
  3. ddATP trisodium

ddATP trisodium (Synonyms: 2',3'-Dideoxyadenosine 5'-triphosphate trisodium)

Cat. No.: HY-128036B
Handling Instructions

ddATP (2',3'-Dideoxyadenosine 5'-triphosphate) trisodium, an active metabolite of 2',3'-dideoxyinosine, is a chain-elongating inhibitor of DNA polymerase. ddATP trisodium can be used for Sanger method for DNA sequencing and research of virus infection.

For research use only. We do not sell to patients.

ddATP trisodium Chemical Structure

ddATP trisodium Chemical Structure

CAS No. : 72029-21-1

Size Stock
5 mg Check price and availability
10 mg Check price and availability
25 mg Check price and availability
50 mg Check price and availability

* Please select Quantity before adding items.

Other Forms of ddATP trisodium:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

ddATP (2',3'-Dideoxyadenosine 5'-triphosphate) trisodium, an active metabolite of 2',3'-dideoxyinosine, is a chain-elongating inhibitor of DNA polymerase. ddATP trisodium can be used for Sanger method for DNA sequencing and research of virus infection[1][2][4].

In Vitro

ddATP (0.05-50 μM, 30 min) trisodium inhibits adenovirus DNA synthesis in isolated nuclei from adenovirus-infected KB cells[1].
ddATP (100 μM, 5 h) trisodium reduces the number of γH2A.X foci in the DSB (DNA double-strand breaks) oocytes[3].
ddATP trisodium inhibits HIV replication by inhibiting HIV reverse transcriptase[5].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Immunofluorescence[3]

Cell Line: DSB oocytes
Concentration: 100 μM
Incubation Time: 5 h
Result: Suppressed the mtDNA replication without fully suppressed the nuclear DNA replication.
Molecular Weight

541.13

Formula

C10H13N5Na3O11P3

CAS No.
SMILES

NC1=NC=NC2=C1N=CN2[[email protected]](O3)CC[[email protected]]3COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (231.00 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8480 mL 9.2399 mL 18.4798 mL
5 mM 0.3696 mL 1.8480 mL 3.6960 mL
10 mM 0.1848 mL 0.9240 mL 1.8480 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
ddATP trisodium
Cat. No.:
HY-128036B
Quantity:
MCE Japan Authorized Agent: