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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
142 Results for "
Mucin
" in MedChemExpress (MCE) Product Catalog:
Products (142)
142 Results for "Mucin" in MCE Product Catalog:
13
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Benzyl-α-GalNAc is a potent O-glycosylation inhibitor. Benzyl-α-GalNAc effectively inhibits the proliferation and activation of LX-2 cells and suppresses the expression of collagen I/III, which has good potential for investigation in liver fibrosis. Benzyl-α-GalNAc also significantly enhances the anti-tumour activity of 5-Fluorouracil (HY-90006) (e.g. pancreatic cancer) by inhibiting O-glycosylation .
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Diquafosol tetrasodium is a P2Y2 receptor agonist that stimulates fluid and mucin secretion on the ocular surface, as a topical treatment of dry eye disease.
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Toluidine Blue (Toluidine Blue O) is an alkaline quinonimine dye (vivo dye) with high affinity for acidic tissue components, staining nuclei blue and polysaccharides purple. Toluidine Blue shows heterostaining properties for mast cells, mucins and chondrocytes. Toluidine Blue can stain different components of plant tissues and cells in different colours. Toluidine Blue is also used as a diagnostic aid to identify malignant lesions, such as cancer .
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Seeds of Cassia tora Linn. Plants Quinones other families Leguminosae Anthraquinones Phenols Polyphenols Disease Research Fields Cancer
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4 Cited Publications
Synonyms: 4-DAMP methiodide
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4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil (5-Fu) (HY-90006) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide (LPS)- and tobacco-induced pulmonary inflammation and reduces mucin 5AC (MUC5AC), oligomeric mucus/gel-forming secretion .
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3 Cited Publications
Cat. No.: HY-B2196
CAS No.: 84082-64-4
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3 Cited Publications
Cat. No.: HY-N0237
CAS No.: 126054-77-1
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2 Cited Publications
Cat. No.: HY-160109
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Ac5GalNTGc is a potent, peracetylated C-2 thioglycolyl-substituted GalNAc analog that efficiently inhibits mucin-type O-glycan biosynthesis. Ac5GalNTGc reduces leukocyte sialyl-Lewis-X expression and inhibits L-/P-selectin mediated rolling under flow, as well as P-selectin dependent leukocyte-platelet adhesion. Ac5GalNTGc exhibits anti-inflammatory activity in a thioglycollate-induced acute peritonitis model. Ac5GalNTGc can be used for studies of O-glycan/mucin biology, inflammation, and related translational research .
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1 Cited Publications
Cat. No.: HY-P99634
CAS No.: 1264737-26-9
Synonyms: PankoMab; DS-3939a antibody
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1 Cited Publications
Cat. No.: HY-P3008
CAS No.: 84195-52-8
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1
1 Cited Publications
Cat. No.: HY-B0393
CAS No.: 13189-98-5
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Fudosteine is a cysteine derivative and a mucoactive agent. Fudosteine inhibits MUC5AC mucin hypersecretion by reducing MUC5AC gene expression .
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1 Cited Publications
Cat. No.: HY-P10218
CAS No.: 479482-23-0
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1 Cited Publications
Cat. No.: HY-P10218A
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1 Cited Publications
Cat. No.: HY-P81703
Synonyms: CD366 antibody;
FLJ14428 antibody;
HAVcr-2 antibody;
Havcr2 antibody;
HAVR2_HUMAN antibody;
Hepatitis A virus cellular receptor 2 antibody;
Kidney injury molecule 3 antibody;
KIM 3 antibody;
KIM3 antibody;
T cell immunoglobulin and Mucin domain containing 3 antibody;
T cell immunoglobulin Mucin 3 antibody;
T-cell immunoglobulin and Mucin domain-containing protein 3 antibody;
T-cell immunoglobulin Mucin family member 3 antibody;
T-cell immunoglobulin Mucin receptor 3 antibody;
T-cell membrane protein 3 antibody;
Tim 3 antibody;
TIM-3 antibody;
TIM3 antibody;
TIMD-3 antibody;
TIMD3 antibody;
Cat. No.: HY-P99539
CAS No.: 2305629-50-7
Synonyms: REGN4018
Cat. No.: HY-177442
Synonyms: DS-3939
Cat. No.: HY-E70562
Mucinase StcE is a zinc metalloproteinase belonging to the M66 family, which is secreted by enterohemorrhagic Escherichia coli via the type II general secretion pathway. Mucinase StcE specifically recognizes and cleaves the 'T*XT' motif in mucin-type glycoproteins with α-O-glycans (such as MUC2, Mucin 7, Glycoprotein 340, CD45, CD43, C1 Esterase Inhibitor (HY-P991629), etc.). By degrading the mucus layer to reduce its viscosity, inhibiting complement cascade activation, and localizing complement regulatory factors to the cell membrane, Mucinase StcE helps bacteria penetrate the mucosal barrier, adhere to host cells, and evade immune clearance. Mucinase StcE can serve as a mucin-specific proteolytic tool for research on mucinous carcinomas derived from the colon, esophagus, and salivary glands .
Cat. No.: HY-P0179
CAS No.: 72122-62-4
Synonyms: β-Casomorphin-7 (bovine); Bovine β-casomorphin-7
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Cat. No.: HY-P991319
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
