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Results for "

NHS

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (138) ADC Payload (3) Antibody-Drug Conjugates (ADCs) (1) Apoptosis (2) Autophagy (1) Bacterial (1) Biochemical Assay Reagents (292) CXCR (1) DNA Stain (4) DNA/RNA Synthesis (2) Drug Derivative (8) Drug Intermediate (8) Drug Metabolite (1) Drug-Linker Conjugates for ADC (10) E3 Ligase Ligand-Linker Conjugates (5) EGFR (1) Exosomes (2) Fluorescent Dye (204) Hapten (1) HIV (1) Integrin (1) Isotope-Labeled Compounds (4) Kinesin (1) Ligands for E3 Ligase (2) Liposome (22) Microtubule/Tubulin (5) MMP (1) OAT (1) Peptide-Drug Conjugates (PDCs) (1) Phosphoramidites (1) PROTAC Linkers (254) PSMA (2) Radionuclide-Drug Conjugates (RDCs) (5) Reference Standards (1) Small Interfering RNA (siRNA) (3) Topoisomerase (2)
By Research Areas:	Cancer (391) Cardiovascular Disease (1) Infection (5) Inflammation/Immunology (9) Metabolic Disease (4) Neurological Disease (4)
Click Chemistry:	ADC Synthesis (53) Labeling and Fluorescence Imaging (1) TCO (17) DBCO (40) PROTAC Synthesis (64) BCN (11) Azide (51) Tetrazine (23) Alkynes (17)
Oligonucleotides:	Pegylated Lipids (26) Thymine (1) Rat Pre-designed siRNA Sets (1) Phospholipids (5) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) Polymers (6) Phosphoramidites (1) siRNAs (3)

940

Inhibitors & Agonists

201

Fluorescent Dye

210

Biochemical Assay Reagents

MCE Kits

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

159

Click Chemistry

Oligonucleotides

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0802

Biotin NHS 15+ Cited Publications Biotin N-hydroxysuccinimide ester; NHS-Biotin	Fluorescent Dye	Others
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.

HY-D1730

*AF488 NHS* ester** 1 Publications Verification	Fluorescent Dye	Others
AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .

HY-W441011

DSPE-NHS	Liposome	Neurological Disease Inflammation/Immunology Cancer
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .

HY-W441014

DSPE-PEG2000-NHS 3 Publications Verification	Liposome	Others
DSPE-PEG2000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG2000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG2000-NHS can be used in the study of drug delivery .

HY-130989

SuO-Glu-Val-Cit-PAB-MMAE NHS-Glutarate-Val-Cit-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
SuO-Glu-Val-Cit-PAB-MMAE (NHS-Glutarate-Val-Cit-PAB-MMAE) consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-150241

DOPE-NHS	Exosomes Biochemical Assay Reagents Liposome	Others
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .

HY-129526

*Mal-PEG3-NHS* ester** 1 Publications Verification	ADC Linker	Cancer
Mal-PEG3-NHS ester is a noncleavable ADC linker containing a Maleimide group. Mal-PEG3-NHS ester is used for making antibody-drug conjugate .

HY-126681

SC-VC-PAB-MMAE 2 Publications Verification NHS-VC-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
SC-VC-PAB-MMAE (NHS-VC-PAB-MMAE) is a agent-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker SC-VC-PAB .

HY-D1567

*Cy7.5 NHS* ester** 1 Publications Verification	Fluorescent Dye	Others
Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study (Ex/Em = 780/820 nm) .

HY-136304

**NHS-PEG1-SS-PEG1-NHS**	PROTAC Linkers	Cardiovascular Disease Metabolic Disease Cancer
NHS-PEG1-SS-PEG1-NHS is a reversible linker for biomacromolecule link with active small molecule. NHS-PEG1-SS-PEG1-NHS can be used in proteins liposomes or nanoparticles .

HY-135413A

*Sulfo-CY5-NHS* ester potassium** Sulfo-Cyanine5 NHS ester potassium	DNA Stain	Inflammation/Immunology Cancer
Sulfo-CY5-NHS ester potassium is a reactive dye and can be used for labeling protein nucleic acid .

HY-D2801A

FITC-PEG1000-NHS	Fluorescent Dye	Others
FITC-PEG1000-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG1000-NHS can be used for fluorescent labeling and imaging .

HY-140129

NHS-SS-biotin	ADC Linker	Cancer
NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W105423

Methacrylic acid N-hydroxysuccinimide ester NHS-MA	Biochemical Assay Reagents	Others
Methacrylic acid N-hydroxysuccinimide ester (NHS-MA) is a polymer that serves as a monomer to prepare degradable amphiphilic block copolymer microparticles via RAFT polymerization for low pH-triggered drug delivery. Methacrylic acid N-hydroxysuccinimide ester is used for the synthesis of nanogels .

HY-126502

*Mal-C2-NHS* ester**	ADC Linker	Others
Mal-C2-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-D1568

*Sulfo-Cy7.5 NHS* ester**	Fluorescent Dye	Others
Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .

HY-156991

NODAGA-NHS NODA-GA-NHS ester	EGFR Radionuclide-Drug Conjugates (RDCs)	Cancer
NODAGA-NHS (NODA-GA-NHS ester) is the activated ester form of the NODAGA chelator. NODAGA-NHS conjugates with Trastuzumab (HY-P9907) to form NODAGA-Trastuzumab, a conjugate that can chelate ⁶⁴Cu for the preparation of radiotracers. NODAGA-NHS covalently binds to the amino group of lactosamine derivatives to form radiotracer precursors. [ ⁶⁴Cu]NODAGA-trastuzumab enables PET imaging of tumors expressing HER2. NODAGA-NHS is used in studies of HER2-positive breast cancer and ovarian adenocarcinoma .

HY-W441013

DSPE-PEG1000-NHS	Liposome	Others
DSPE-PEG1000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG1000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG1000-NHS can be used in the study of drug delivery .

HY-150014

AMT-NHS	Others	Others
AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells .

HY-174893

*Azido-PEG20-NHS* ester**	Biochemical Assay Reagents	Others
Azido-PEG20-NHS ester is a PEG derivative that can be used for drug delivery and other research. Azido-PEG20-NHS ester is a click chemistry reagent. Azido-PEG20-NHS contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group. Azido-PEG20-NHS can also undergo ring strain driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .

HY-160773

*DBCO-PEG6-NHS* ester**	Biochemical Assay Reagents	Others
DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-164165

*Paclitaxel-2′-succinate NHS* ester**	Microtubule/Tubulin Drug Derivative	Cancer
Paclitaxel-2′-succinate NHS ester is a paclitaxel derivative with a succinic acid linker, in which the carboxyl group is activated by the NHS ester. The NHS ester group is highly reactive toward amino or hydroxyl groups and can be used to conjugate with other molecules such as peptides, proteins, antibodies, enzymes or polymers. Paclitaxel-2′-succinate NHS ester can be used in the development of nanomedicines and in the study of cancer therapy .

HY-136133

**NHS-PEG2-SS-PEG2-NHS**	ADC Linker	Cancer
NHS-PEG2-SS-PEG2-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W190908A

*Desthiobiotin-PEG4-NHS* ester**	Biochemical Assay Reagents	Others
Desthiobiotin-PEG4-NHS ester is a PEG derivative composed of desthiobiotin, 4 PEG units, and NHS ester. NHS ester can be conjugated to amino acids or other molecules containing amino groups.

HY-176879

NHS-PEG2000-Mannose	Drug Derivative Bacterial	Infection
NHS-PEG2000-Mannose is an NHS-PEG-Mannose containing PEG2000. NHS-PEG-Mannose is a D-mannose derivative and linker. NHS-PEG-Mannose can bind to phage coat proteins via amino-carboxyl reaction to form mannose-modified phage (Man-phage) .

HY-139326

NHS-MMAF	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
NHS-MMAF is a modified MMAF extracted from patent WO2012143499, intermediat 219. MMAF is a potent tubulin polymerization inhibitor and is used as a antitumor agent

HY-D2178

*AF 568 NHS* ester**	Fluorescent Dye	Others
AF 568 NHS ester is a derivative of the orange fluorescent dye AF 568. AF 568 NHS ester is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling. AF 568 exhibits maximum absorption wavelength of 579 nm and the maximum emission wavelength of 603 nm .

HY-164862

*N-(NHS* ester-PEG2)-N-bis(PEG3-azide)**	PROTAC Linkers	Others
N-(NHS ester-PEG2)-N-bis(PEG3-azide) is a PEG linker with an NHS ester group and two terminal azide groups. N-(NHS ester-PEG2)-N-bis(PEG3-azide) can be utilized in Click Chemistry .

HY-135413B

*MeCY5-NHS* ester triethylamine** 1 Publications Verification Sulfo-Cyanine5 NHS ester triethylamine	DNA Stain	Others
MeCY5-NHS ester (potassium) is a reactive dye and can be used for labeling protein nucleic acid .

HY-W441016

DSPE-PEG5000-NHS	Liposome	Others
DSPE-PEG5000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG5000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG5000-NHS can be used in the study of drug delivery .

HY-140341A

*Sulfo-NHS-Acetate sodium*	PROTAC Linkers	Others
Sulfo-NHS-Acetate sodium is an alkyl chain-based PROTAC linker. Sulfo-NHS-Acetate sodium can be used in the synthesis of PROTACs .

HY-147117

NHS-SS-Ac	Biochemical Assay Reagents	Others
NHS-SS-Ac is an amine-reactive product synthesized from acetic acid .

HY-W012166

N-Succinimidyl bromoacetate NHS-Bromoacetate	Biochemical Assay Reagents	Infection
N-Succinimidyl bromoacetate (NHS-Bromoacetate) is a heterobifunctional crosslinking reagent, mainly used to modify the ɛ-amino group of lysine side chains. By covalently linking its bromoacetyl moiety to the ɛ-amino group of lysine in peptidomimetics, N-Succinimidyl bromoacetate enables their conjugation with thiol-modified nanoparticles via thioether bonds. N-Succinimidyl bromoacetate also performs bromoacetylation modification on carrier proteins, which then forms stable thioether bonds with the thiol groups of cysteine in peptides, thus efficiently preparing soluble peptide-protein conjugates with high substitution ratios. N-Succinimidyl bromoacetate can be used to prepare activated Sepharose derivatives for affinity chromatography, protein affinity labeling reagents, and peptide-protein immunogen conjugates with non-immunogenic linkages. N-Succinimidyl bromoacetate is applicable to studies related to HIV-1 infection and glioblastoma multiforme .

HY-D2801B

FITC-PEG3400-NHS	Fluorescent Dye	Others
FITC-PEG3400-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG3400-NHS can be used for fluorescent labeling and imaging .

HY-W190908C

*Desthiobiotin-PEG12-NHS* ester**	Biochemical Assay Reagents	Others
Desthiobiotin-PEG12-NHS ester is a PEG derivative composed of desthiobiotin, 12 PEG units, and NHS ester. NHS ester can be conjugated to amino acids or other molecules containing amino groups.

HY-W190908B

*Desthiobiotin-PEG6-NHS* ester**	Biochemical Assay Reagents	Others
Desthiobiotin-PEG6-NHS ester is a PEG derivative composed of desthiobiotin, 6 PEG units, and NHS ester. NHS ester can be conjugated to amino acids or other molecules containing amino groups.

HY-D2956

BC-GLA-NHS CLIP-GLA-NHS	Biochemical Assay Reagents	Others
BC-GLA-NHS (CLIP-GLA-NHS) is a NHS-labeled CLIP tag, which is an amine-reactive crosslinker and can achieve site-specific protein labeling. The NHS ester of BC-GLA-NHS reacts with the primary amine of the target molecule (such as antibodies, quantum dots) in a pH 7.5-8.5 buffer solution to form a stable amide bond. After coupling, the BC molecule undergoes a nucleophilic substitution reaction with the active site (Cys) of the CLIP-tagged fusion protein, releasing benzylcytosine and forming an irreversible thioether bond, achieving covalent labeling. BC-GLA-NHS can be used for click chemistry labeling .

HY-W441012

DSPE-PEG600-NHS	Liposome	Others
DSPE-PEG600-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG600-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG600-NHS can be used in the study of drug delivery .

HY-174888

*DBCO-PEG16-NHS* ester**	Biochemical Assay Reagents	Others
DBCO-PEG16-NHS ester is a PEG derivative consisting of DBCO, PEG units, and NHS ester. NHS ester can bind to amino acids or other molecules containing amino groups. DBCO-PEG16-NHS ester contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .

HY-D0167

NHS-5(6)Carboxyrhodamine	Fluorescent Dye	Others
NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions .

HY-D2291

*BODIPY TMR NHS* ester**	Fluorescent Dye	Others
BODIPY TMR NHS ester is bright, orange fluorescent dye with Ex/Em of 544/570 nm. The NHS ester (or succinimidyl ester) of BODIPY TMR NHS ester is a popular tool for conjugating the dye to a protein or antibody. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .

HY-151686

Bz-(Me)Tz-NHS	Biochemical Assay Reagents	Others
Bz-(Me)Tz-NHS is a methyltetrazine carboxylic acid NHS ester that enables conjugation of the tetrazine moiety to the 5' end of oligonucleotides via amide coupling reaction, and it is used in oligonucleotide template-mediated fluorescent bioorthogonal cycloaddition reactions. Bz-(Me) Tz-NHS is applicable to click chemistry-related studies .

HY-D2801

FITC-PEG400-NHS	Fluorescent Dye	Others
FITC-PEG400-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG400-NHS can be used for fluorescent labeling and imaging .

HY-177502

NHS-cBu-Cit-PAB	Drug Intermediate ADC Linker	Others
NHS-cBu-Cit-PAB is an intermediate of ADC linker. NHS-cBu-Cit-PAB can be used for synthesis of antibody-drug conjugates (ADCs) .

HY-138522

NHS-bis-PEG2-amide-Mal	PROTAC Linkers	Cancer
NHS-bis-PEG2-amide-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-157338

NHS-Ala-Ala-Asn-active metabolite	ADC Linker Kinesin	Cancer
NHS-Ala-Ala-Asn-active metabolite is a cleavable antibody-drug conjugate (ADC) linker for synthesis of kinesin spindle protein (KSP)inhibitor .

HY-141124

NHS-PEG4-(m-PEG4)3-ester	PROTAC Linkers	Cancer
NHS-PEG4-(m-PEG4)3-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-141166A

*(S,E)-TCO2-PEG3-NHS* ester**	Biochemical Assay Reagents	Cancer
(S,E)-TCO2-PEG3-NHS ester is NH₂ reactive, and can be used in chemical synthesis. (S,E)-TCO2-PEG3-NHS ester contains TCO groups, which can undergo specific "click" reactions with tetrazine groups .

HY-D2290

*Demethoxy-BODIPY TMR NHS* ester**	Fluorescent Dye	Others
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .

HY-160773A

*DBCO-C3-amide-PEG6-NHS* ester**	Biochemical Assay Reagents	Others
DBCO-C3-amide-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-C3-amide-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

Cat. No.	Product Name

HY-K0227

NHS Magnetic Beads (200nm, 10 mg/mL)
MCE NHS Magnetic Beads (200 nm, 10 mg/mL) contain N-hydroxysuccinimide (NHS) functional groups, which react with primary amines on proteins or other molecules to form stable amide linkages，can covalently immobilize proteins for the affinity purification of antibodies, antigens and other biomolecules.

HY-KD1113

Biotinylated Rapid Labeling Kit

The Biotinylation Rapid Labelling Kit enables biotinylation of proteins. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled within a pH 7-9 solution, forming stable amide bonds to achieve conjugation with the antibody/protein. Typically, a single IgG molecule can bind 2-8 molecules of biotin. The entire procedure can be completed within two hours.

HY-KD1115

DOTA Rapid Labeling Kit

The DOTA rapid labelling kit enables DOTA labelling of proteins. Based on NHS ester chemistry, NHS ester-activated fluorescent dyes react with primary amines on the antibody/protein to form stable amide bonds at pH 7–9, thereby achieving conjugation with the antibody/protein. Typically, a single IgG molecule can bind 2–8 DOTA molecules. The entire procedure can be completed within 2 hours.

HY-KD1114

Nota Rapid Labeling Kit

The NOTA Rapid Labelling Kit enables NOTA labelling of proteins. Based on NHS ester chemistry, NHS ester-activated fluorescent dyes react with primary amines on the antibody/protein to be labelled in a pH 7-9 solution, forming stable amide bonds to achieve conjugation with the antibody/protein. Typically, a single IgG molecule can bind 2–8 NOTA molecules. The entire procedure can be completed within two hours.

HY-KD1101

Green Fluorescent Rapid Labeling Kit (FITC）

Green Fluorescent Rapid Labelling Kit (FITC) enables green fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 488/515 nm. Based on NHS-ester chemistry, the NHS-ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of FITC. The entire procedure can be completed within two hours.

HY-KD1106

Deep Red Fluorescent Rapid Labeling Kit (AF647）

Red Fluorescent Rapid Labelling Kit (AF647) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 647/665 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of AF647. The entire procedure can be completed within two hours.

HY-KD1112

Blue Fluorescent Rapid Labeling Kit (AF350）

TheBlue Fluorescence Rapid Labelling Kit (AF350) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 346/442 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of AF350. The entire procedure can be completed within two hours.

HY-KD1103

Red Fluorescent Rapid Labeling Kit (CY3）

Red Fluorescent Rapid Labelling Kit (CY3) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 550/570 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation with the antibody/protein. Typically, one IgG molecule can bind 2–8 molecules of CY3. The entire experiment can be completed within 2 hours.

HY-KD1107

Deep Red Fluorescent Rapid Labeling Kit (CY5）

Deep Red Fluorescent Rapid Labelling Kit (CY5) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 649/667 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2–8 molecules of CY5. The entire experiment can be completed within 2 hours.

HY-KD1111

NIR Red Fluorescent Rapid Labeling Kit (AF750）

Near-infrared Fluorescent Rapid Labelling Kit (AF750) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 750/775 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of AF750. The entire procedure can be completed within two hours.

HY-KD1102

Green Fluorescent Rapid Labeling Kit (AF488）

Green Fluorescent Rapid Labelling Kit (AF488) enables green fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 480/525 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of AF488. The entire procedure can be completed within two hours.

HY-KD1105

Red Fluorescent Rapid Labeling Kit (AF594）

Red Fluorescent Rapid Labelling Kit (AF594) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 594/617 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of AF594. The entire procedure can be completed within two hours.

HY-KD1104

Red Fluorescent Rapid Labeling Kit (AF555）

Red Fluorescent Rapid Labelling Kit (AF555) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 555/565 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds with the target antibody/protein, achieving conjugation. Typically, one IgG molecule can bind 2-8 molecules of AF555. The entire procedure can be completed within two hours.

HY-KD1109

NIR Red Fluorescent Rapid Labeling Kit (CY7）

Near-infrared Fluorescent Rapid Labelling Kit (CY7) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 750/773 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2–8 molecules of CY7. The entire experiment can be completed within 2 hours.

HY-KD1108

Deep Red Fluorescent Rapid Labeling Kit (CY5.5）

Deep Red Fluorescent Rapid Labelling Kit (CY5.5) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 678/695 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of CY5.5. The entire procedure can be completed within two hours.

HY-KD1110

NIR Red Fluorescent Rapid Labeling Kit (CY7.5）

The Near-Infrared Fluorescence Rapid Labelling Kit (CY7.5) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 788/814 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of CY7.5. The entire procedure can be completed within two hours.

Cat. No.	Product Name	Target	Research Area	Image

HY-P99239

Rosopatamab HUJ-591; TLX591	PSMA Radionuclide-Drug Conjugates (RDCs)	Cancer
Rosopatamab (HuJ591) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cancer. Rosopatamab can be linked to the low-energy beta-emitting radioisotope lutetium-177 ( ¹⁷⁷Lu) through the bifunctional chelator DOTA-NHS ester to obtain a radioimmunoconjugate that targets malignant prostate cells with high efficiency .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N16296

*Cyanine 7.5 NHS* chloride**	Structural Classification Lipid	Fluorescent Dye
Cy7.5 NHS ester chloride is a fluorescent dye. Cy7.5 NHS ester chloride can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester chloride can be used for fluorescent imaging study (Ex/Em = 780/820 nm) .

HY-D1596B

(E)-Cyanine 3.5 chloride (E)-Cy3.5 NHS ester chloride; (E)-Cy 3.5 chloride	Lipid	Fluorescent Dye
(E)-Cyanine 3.5 ((E)-Cy3.5 NHS ester) chloride is a cyanine dye functionalized with a N-hydroxysuccinimide (NHS) group. (E)-Cyanine 3.5 chloride contains NHS groups that react with ammonia to form ester bonds (Ex/Em = 586/612 nm).

HY-N15975

12:0 N-Biotinyl fatty acid, NHS	Lipid	Biochemical Assay Reagents
12:0 N-Biotinyl fatty acid, NHS is a biotinylated lipid. 12:0 N-Biotinyl fatty acid, NHS contains NHS groups that react with ammonia to form ester bonds .

Cat. No.	Product Name	Chemical Structure

HY-118431S3

*DMABA-d10 NHS* ester**
DMABA-d₁₀ NHS ester is the deuterium labeled DMABA NHS ester .

HY-118431S2

*DMABA-d6 NHS* ester**
DMABA-d₆ NHS ester is the deuterium labeled DMABA NHS ester .

HY-118431S

*DMABA-d4 NHS* ester**
DMABA-d₄ NHS ester is the deuterium labeled DMABA NHS ester .

HY-145547S

1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-d27

1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-d₂₇ (14:0 Lyso PE-d₂₇) is the deuterium labeled 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine. 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells .

Cat. No.	Product Name		Classification

HY-W441011

DSPE-NHS		Phospholipids
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .

HY-W441014

DSPE-PEG2000-NHS 3 Publications Verification		Pegylated Lipids
DSPE-PEG2000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG2000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG2000-NHS can be used in the study of drug delivery .

HY-150241

DOPE-NHS		Phospholipids
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .

HY-W591424

*m-PEG2000-NHS* ester** mPEG2000-SC; mPEG2000-Succinimidyl ester		Polymers
m-PEG2000-NHS ester (mPEG2000-SC) is a reagent with both cell adhesion inhibition and peptide conjugation functions. The *NHS* ester group of m-PEG2000-NHS ester forms stable amide bonds with primary amine-containing molecules (e.g., the N-terminus of MMP-2-cleavable octapeptide) to generate mPEG-peptide intermediates for liposome surface modification. When m-PEG2000-NHS ester is immobilized on a cystamine-modified gold surface, it can construct an in vitro model for cell adhesion kinetic studies, and higher PEG density and thicker layers correlate with lower cell adhesion rates. m-PEG2000-NHS ester can synthesize MMP-2-responsive PEGylated lipid conjugates to achieve MMP-triggered dePEGylation in the tumor microenvironment. m-PEG2000-NHS ester can be used in studies related to colon cancer and other conditions .

HY-174264

DMG-PEG2000-NHS		Pegylated Lipids
DMG-PEG2000-NHS is a polyethylene glycol lipid with a molecular weight of 2000, which can be used to construct novel drug delivery systems that confer mucoadhesive and cell-targeting capabilities to lipid nanoparticles .

HY-W441013

DSPE-PEG1000-NHS		Pegylated Lipids
DSPE-PEG1000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG1000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG1000-NHS can be used in the study of drug delivery .

HY-155909A

*m-PEG1000-NHS* ester** mPEG1000-SC; mPEG1000-Succinimidyl ester		Polymers
m-PEG1000-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-W440702

Cholesterol-PEG2000-NHS		Pegylated Lipids
Cholesterol-PEG2000-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG2000-NHS can be used in drug delivery research .

HY-W441015A

DSPE-m-PEG3400-NHS		Pegylated Lipids
DSPE-m-PEG3400-NHS is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine .

HY-157745

*m-PEG40000-NHS* ester** mPEG40000-SC; mPEG40000-Succinimidyl ester		Polymers
m-PEG-NHS ester (mPEG-SC; mPEG-Succinimidyl ester) (MW 40000) is a polyethylene glycol derivative. m-PEG-NHS ester serves as a modifying agent that reacts with free amino groups on the surface of protein or polypeptide molecules to form stable amide bonds, thereby covalently linking PEG chains to biomacromolecules, improving their antigenicity and immunogenicity, and facilitating the preparation of injectable formulations .

HY-W441016

DSPE-PEG5000-NHS		Pegylated Lipids
DSPE-PEG5000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG5000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG5000-NHS can be used in the study of drug delivery .

HY-W440697

Cholesterol-PEG1000-NHS		Pegylated Lipids
Cholesterol-PEG1000-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG1000-NHS can be used in drug delivery research .

HY-155909C

*m-PEG350-NHS* ester** mPEG350-SC; mPEG350-Succinimidyl ester		Polymers
m-PEG350-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-W441002

DSPE-succinic acid		Phospholipids
DSPE-succinic acid is a derivative of Succinic acid (HY-N0420) and an intermediate of DSPE-Doxorubicin. DSPE-succinic acid can be used to synthesize DSPE-Doxorubicin via EDC/NHS activation. DSPE-succinic acid is applicable to the research of triple-negative breast cancer .

HY-W440706

Cholesterol-PEG2000-alcohol		Pegylated Lipids
Cholesterol-PEG2000-alcohol is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.

HY-W441012

DSPE-PEG600-NHS		Pegylated Lipids
DSPE-PEG600-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG600-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG600-NHS can be used in the study of drug delivery .

HY-W440927

Stearic acid-PEG2000-NHS		Pegylated Lipids
Stearic acid-PEG2000-NHS is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The NHS ester is reactive with amine to form a stable amide bond. Reagent grade, for research purpose.

HY-W441014B

*DSPE-PEG20000-NHS* ammonium**		Pegylated Lipids
DSPE-PEG20000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles .

HY-155909

*m-PEG3400-NHS* ester** mPEG3400-SC; mPEG3400-Succinimidyl ester		Polymers
m-PEG3400-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-W440704

Cholesterol-PEG5000-NHS		Pegylated Lipids
Cholesterol-PEG5000-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG5000-NHS can be used in drug delivery research .

HY-W441014A

*DSPE-PEG10000-NHS* ammonium**		Pegylated Lipids
DSPE-PEG10000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles .

HY-155909B

*m-PEG550-NHS* ester** mPEG550-SC; mPEG550-Succinimidyl ester		Polymers
m-PEG550-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-W440926

Stearic acid-PEG1000-NHS		Pegylated Lipids
Stearic acid-PEG1000-NHS is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond.

HY-W440945

Stearic acid-PEG2000-amine		Pegylated Lipids
Stearic acid-PEG2000-amine is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The terminal amine can react with an NHS ester to form a stable amide linkage. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer. Reagent grade, for research use only.

HY-W440703

Cholesterol-PEG3400-NHS		Pegylated Lipids
Cholesterol-PEG3400-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG3400-NHS can be used in drug delivery research .

HY-174264B

DMG-PEG3400-NHS		Pegylated Lipids
DMG-PEG3400-NHS is a PEG derivative that can be used to construct drug delivery vehicles.

HY-174264C

DMG-PEG5000-NHS		Pegylated Lipids
DMG-PEG5000-NHS is a PEG derivative that can be used to construct drug delivery vehicles.

HY-W440928

Stearic acid-PEG3400-NHS		Pegylated Lipids
Stearic acid-PEG3400-NHS is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA.

HY-RS22963

Nhs Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Nhs Rat Pre-designed siRNA Set A contains three designed siRNAs for Nhs gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS16532

Nhs Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Nhs Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nhs gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-W441005

Amino-Gly-Gly-DSPE hydrochloride		Phospholipids
Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used to synthesize liposomes. The terminal amine is reactive with an NHS ester compound or carboxylic acid molecule in the presence of activator, such as HATU or EDC.

HY-172270D

DSPE-PEG5000-Mal-Cys-KTLLPTP		Pegylated Lipids
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .

HY-172270

DSPE-PEG1000-Mal-Cys-KTLLPTP		Pegylated Lipids
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .

HY-172270A

DSPE-PEG2000-Mal-Cys-KTLLPTP		Pegylated Lipids
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .

HY-W440807

Oleoyl-Gly-Lys-(m-PEG11)-NH2		Pegylated Lipids
Oleoyl-Gly-Lys-(m-PEG11)-NH2 is a PEG-lipid molecule featuring an oleoyl amide linked to a Gly-Lys dipeptide and a methoxy PEG11 chain on the C-terminus of the lysine. The lysine primary amine may be used in a wide variety of reactions with carboxylic acids, NHS esters, and carbonyl groups. The PEG linker provides aqueous solubility.

HY-145547

1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine 14:0 Lyso PE; 1-Myristoyl-2-hydroxy-sn-glycero-3-PE; 1-Tetradecanoyl-sn-glycero-3-phosphoethanolamine		Phospholipids
1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells . Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls .

HY-174264A

DMG-PEG1000-NHS		Pegylated Lipids
DMG-PEG1000-NHS is a PEG derivative that can be used to construct drug delivery vehicles.

HY-182234

NHS-Carboxy-dT		Phosphoramidites Thymine
NHS-Carboxy-dT is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-W441014C

*DSPE-PEG40000-NHS* ammonium**		Pegylated Lipids
DSPE-PEG40000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles .

HY-RS09290

NHS Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
NHS Human Pre-designed siRNA Set A contains three designed siRNAs for NHS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-172270C

DSPE-PEG3400-Mal-Cys-KTLLPTP		Pegylated Lipids
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-42972G

DBCO-acid	Biochemical Assay Reagents	Cancer
DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-W1048843AG

4-Arm PEG5000-NH2 4-Arm PEG5000-amine	Biochemical Assay Reagents	Others
4-Arm PEG5000-NH2 (GMP) (4-Arm PEG5000-amine (GMP)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048843AGL

4-Arm PEG5000-NH2 (GMP Like) 4-Arm PEG5000-amine (GMP Like)	Biochemical Assay Reagents	Others
4-Arm PEG5000-NH2 (GMP Like) (4-Arm PEG5000-amine (GMP Like)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP like guidelines. GMP like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

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