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Results for "

NO

" in MedChemExpress (MCE) Product Catalog:

By Targets:	NO Synthase (113) 5-HT Receptor (5) ADC Linker (7) Adrenergic Receptor (5) Akt (4) Aldose Reductase (1) Amino Acid Derivatives (3) AMPK (1) Angiotensin Receptor (3) Antibiotic (2) Apoptosis (18) Arginase (2) Autophagy (4) Bacterial (9) Bcl-2 Family (2) Biochemical Assay Reagents (20) Calcium Channel (6) Calmodulin (1) Caspase (4) Cathepsin (1) Cholinesterase (ChE) (2) COX (21) Cytochrome P450 (3) Dengue Virus (3) DNA/RNA Synthesis (2) Drug Derivative (14) Drug Intermediate (3) Drug Metabolite (2) E3 Ligase Ligand-Linker Conjugates (1) Endogenous Metabolite (24) Environmental Pollutants (7) Epigenetic Reader Domain (1) ERK (3) Flavivirus (1) Fluorescent Dye (23) Formyl Peptide Receptor (FPR) (1) Fungal (3) FXR (1) GABA Receptor (12) GDNF Receptor (1) Glycosidase (1) Guanylate Cyclase (12) HCV (1) HDAC (3) Hemoglobin (1) HIF/HIF Prolyl-Hydroxylase (1) Histamine Receptor (1) HIV (8) HIV Protease (5) HSV (2) IFNAR (2) IKK (2) Indoleamine 2,3-Dioxygenase (IDO) (2) Influenza Virus (1) Interleukin Related (18) IRE1 (1) Isotope-Labeled Compounds (10) JAK (1) Keap1-Nrf2 (1) Lactate Dehydrogenase (1) Ligands for E3 Ligase (2) Lipase (1) Liposome (1) Lipoxygenase (2) MEK (1) Microtubule/Tubulin (2) MMP (2) MOFs (2) Monoamine Oxidase (5) mTOR (1) NF-κB (25) NOD-like Receptor (NLR) (2) Nucleoside Antimetabolite/Analog (1) Opioid Receptor (1) Oxytocin Receptor (1) P2X Receptor (1) P2Y Receptor (1) p38 MAPK (2) Paraptosis (1) Parasite (1) PCSK9 (1) Phosphodiesterase (PDE) (15) PI3K (3) PKC (1) Potassium Channel (3) PROTAC Linkers (3) Radionuclide-Drug Conjugates (RDCs) (4) Reactive Oxygen Species (ROS) (18) Reference Standards (31) REV-ERB (1) Reverse Transcriptase (1) ROS Kinase (2) Ser/Thr Protease (1) Serine Racemase (SR) (1) Small Interfering RNA (siRNA) (2) Sodium Channel (2) Src (1) STAT (2) Thrombin (2) TNF Receptor (10) Toll-like Receptor (TLR) (7) Trk Receptor (1) Tyrosinase (2) Virus Protease (3) α-synuclein (1)
By Research Areas:	Cancer (70) Cardiovascular Disease (66) Endocrinology (10) Infection (35) Inflammation/Immunology (172) Metabolic Disease (31) Neurological Disease (51)
Click Chemistry:	Azide (1) Alkynes (2)
Oligonucleotides:	Pegylated Lipids (1) CpG ODNs (2) Solubilizing Agents (1) Mouse Pre-designed siRNA Sets (1) siRNA drugs (1) siRNAs (2)

372

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

123

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: WNK Kinase NO Synthase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-121526

S-Nitroso-N-acetyl-DL-penicillamine 5+ Cited Publications SNAP	NO Synthase	Cardiovascular Disease Cancer
S-Nitroso-N-acetyl-DL-penicillamine (SNAP) is a nitric oxide donor and acts as a stable inhibitor of platelet aggregation .

HY-D0915

Brilliant Blue FCF 5 Publications Verification Acid Blue 9; FD&C Blue NO. 1; E133	Environmental Pollutants Fluorescent Dye	Others
Brilliant Blue FCF is an aromatic hydrocarbon, a synthetic dye produced from petroleum and used as a colorant for food and other substances. The solution has a maximum absorption at 628 nm.

HY-B0696A

Tiagabine hydrochloride NO050328 hydrochloride; NO328 hydrochloride; TGB hydrochloride	GABA Receptor	Neurological Disease
Tiagabine hydrochloride (NO050328; NO328; TGB) is an orally active, highly selective, and reversible GAT-1 inhibitor and anticonvulsant that crosses the blood-brain barrier. By blocking the reuptake of GABA in neurons and glial cells, tiagabine increases extracellular GABA levels to enhance inhibitory signal transduction, thereby exerting multiple activities such as anticonvulsant, neuroprotective, and antioxidant effects. Tiagabine hydrochloride exhibits linear pharmacokinetic properties. Although it is metabolized by CYP3A and has a high protein binding rate, it carries a low risk of cognitive impairment. Tiagabine hydrochloride is widely used in research on related diseases including epilepsy (including refractory partial seizures), alcohol withdrawal symptoms, and Huntington's disease .

HY-D0257

Tartrazine 1 Publications Verification Acid Yellow 23; FD&C Yellow NO. 5	Environmental Pollutants Fluorescent Dye	Cardiovascular Disease Neurological Disease
Tartrazine (Acid Yellow 23; FD&C Yellow No. 5) is an orally active azo acid dye, orange-yellow powder, soluble in water and turns yellow. Tartrazine is mainly used as a synthetic lemon yellow azo dye for food coloring. Tartrazine is the most stable colorant.Tartrazine induces mitochondria-mediated Apoptosis. Tartrazine can cause neurodevelopmental toxicity, cytotoxicity, and genotoxicity .

HY-D0914

Fast Green FCF FD&C Green NO. 3; Food green 3; C.I. 42053	Environmental Pollutants α-synuclein	Neurological Disease
Fast Green FCF is a sea green triarylmethane food dye, with absorption maximum ranging from 622 to 626 nm. Fast Green FCF inhibits α-synuclein aggregation, as well as Aβ and P2X4 receptor, and TLR4/Myd88/NF-κB. Fast Green FCF is widely used as a staining agent like quantitative stain for histones at alkaline pH after acid extraction of DNA, and as a protein stain in electrophoresis. Fast Green FCF improves cognitive impairment, depression, relieves pain allergies, and promotes reproductive function .

HY-D0717

DAF-FM DA Maximum Cited Publications 14 Publications Verification DiamiNOfluorescein-FM diacetate	Fluorescent Dye	Cancer
DAF-FM DA (Diaminofluorescein-FM diacetate) is a fluorescent probe for the detection and bioimaging of nitric oxide (NO). DAF-FM DA spontaneously crosses the plasma membrane and is subsequently cleaved by esterases to generate intracellular DAF-FM (Ex/Em=495/515 nm) .

HY-B0696

Tiagabine NO050328; NO328; TGB	GABA Receptor	Neurological Disease
Tiagabine (NO050328; NO328; TGB) is an orally active, highly selective, and reversible GAT-1 inhibitor and anticonvulsant that crosses the blood-brain barrier. By blocking the reuptake of GABA in neurons and glial cells, tiagabine increases extracellular GABA levels to enhance inhibitory signal transduction, thereby exerting multiple activities such as anticonvulsant, neuroprotective, and antioxidant effects. Tiagabine exhibits linear pharmacokinetic properties. Although it is metabolized by CYP3A and has a high protein binding rate, it carries a low risk of cognitive impairment. Tiagabine is widely used in research on related diseases including epilepsy (including refractory partial seizures), alcohol withdrawal symptoms, and Huntington's disease .

HY-123630

Allura Red AC FD&C RED NO. 40; CI 16035	Environmental Pollutants Fluorescent Dye 5-HT Receptor Interleukin Related Reactive Oxygen Species (ROS) IFNAR	Inflammation/Immunology
Allura Red AC is a food colorant, appearing as a deep red water-soluble powder or granules, used in various applications such as beverages, syrups, candies, and cereals. Allura Red AC can statically quench the intrinsic fluorescence of HSA. Additionally, Allura Red AC is a 5-hydroxytryptamine (5-HT) pathway-associated pro-inflammatory agent, capable of exacerbating experimental colitis. Allura Red AC holds potential for research in inflammatory bowel disease (IBD), intestinal barrier function, and food additive safety .

HY-N1442

Acid orange 7 Orange II; D&C Orange NO. 4	Environmental Pollutants Biochemical Assay Reagents	Others
Acid Orange 7 (Orange II; D&C Orange NO. 4) is an azo dye widely used in the textile, food and cosmetic industries. Acid Orange 7 is mainly used as a colorant by combining with fibers and other substances through azo bonds. Acid Orange 7 has a maximum absorption wavelength at 484-485 nm, and the concentration is measured using a UV-visible spectrophotometer. Acid Orange 7 is difficult to degrade and has a certain degree of toxicity. It is often used to study various sewage treatment technologies and photocatalytic degradation reactions, and to evaluate the removal effects of different treatment methods on organic pollutants .

HY-D0307A

Amaranth Acid Red 27; Azorubin S; FD & C Red Dye NO. 2	Environmental Pollutants Biochemical Assay Reagents	Inflammation/Immunology
Amaranth is an organic azo dye. Amaranth inhibits cellular immune response. Amaranth can be used as a food additive .

HY-D0076

4,5-Diaminofluorescein DAF-2	Fluorescent Dye	Cancer
4,5-Diaminofluorescein is a fluorescent detector for nitric oxide (NO) in cells and tissues .

HY-D1266

RB-OPD NO-red	Fluorescent Dye	Others
RB-OPD (NO-red) is a o-phenylenediamine (OPD)-locked rhodamine nitric oxide (NO) fluorescent probe with great sensitivity and selectivity (λex=550 nm, λem=590 nm) .

HY-117549

Ibrolipim NO-1886	Lipase	Cardiovascular Disease
Ibrolipim (NO-1886) is an orally active lipoprotein lipase (LPL)-promoting agent. Ibrolipim decreases plasma triglycerides, increases high-density lipoprotein cholesterol levels. Ibrolipim has renoprotective and hypolipidemic effects .

HY-103506

NNC-711 NO-711 hydrochloride	GABA Receptor	Neurological Disease
NNC-711 (NO-711 hydrochloride) is a potent and selective inhibitor of GAT-1 (GABA transporter 1) with IC₅₀ values of 0.04, 0.38, 171, 1700, 349, 622 μM for human GAT-1, rat GAT-1, rGAT-2, hGAT-3, rGAT-3, hBGT-3, respectively. NNC-711 has anticonvulsant and analgesic effect in vivo and exhibits cognition-enhancing activity .

HY-143220

SS(no Galnac)-Inclisiran sodium	PCSK9 Small Interfering RNA (siRNA) Drug Derivative	Cardiovascular Disease
SS (no Galnac)-Inclisiran sodium is the sense strand of Inclisiran (HY-132591) without GalNAc modification. Inclisiran is a double-stranded small interfering RNA (siRNA) molecule that inhibits the transcription of PCSK-9. SS (no Galnac)-Inclisiran sodium can be used in cardiovascular disease research .

HY-DY1048

DAF-FM DA (solution)	Fluorescent Dye	Cancer
DAF-FM DA (Diaminofluorescein-FM diacetate) (solution) is a fluorescent probe for the detection and bioimaging of nitric oxide (NO). DAF-FM DA spontaneously crosses the plasma membrane and is subsequently cleaved by esterases to generate intracellular DAF-FM (Ex/Em=495/515 nm) . Solvent and concentration: DMSO: 2 mM

HY-W717800A

NO2A-Azide trihydrochloride	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Others
NO2A-Azide (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Azide (trihydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W040067

Boc-Arg(NO2)-OH	Amino Acid Derivatives	Others
Boc-Arg(NO2)-OH is an arginine derivative .

HY-W014405

H-DL-Phe(4-NO2)-OH	Amino Acid Derivatives	Others
H-DL-Phe(4-NO2)-OH is a phenylalanine derivative .

HY-P5313A

Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr acetate	Dengue Virus	Infection
Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr acetate is a DEN protease substrate, which can be used in research related to dengue virus (drug development) .

HY-W507393

Dipropylenetriamine NONOate DPTA-NO	Biochemical Assay Reagents	Others
Dipropylenetriamine NONOate (DPTA-NO) is a NO donor, which spontaneously dissociates in a pH-dependent, first-order process with a half-life of three hours and five hours at 37°C and 22-25°C, pH 7.4, respectively .

HY-W587780

Sulfamethoxazole-NO SMX-NO	Biochemical Assay Reagents	Inflammation/Immunology
Sulfamethoxazole-NO (SMX-NO) is the major immunogen in sulfonamide allergy, producing modest ascorbic acid depletion and hemoglobin adduct formation. Sulfamethoxazole-NO haptens tissue proteins and is immunogenic in rodents .

HY-101757

NO-prednisolone NCX-1015	Interleukin Related	Inflammation/Immunology
NO-prednisolone is a nitric oxide (NO)-releasing derivative of Prednisolone. NO-prednisolone potently stimulates IL-10 production in vivo.

HY-W575237

Desamino lenalidomide-NO2	Ligands for E3 Ligase	Cancer
Desamino lenalidomide-NO2 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-NO2 can be linked to a target protein ligand via a linker to form a PROTAC.

HY-171995

Rf470 TFA Rotor NO.4 TFA	Fluorescent Dye Bacterial	Infection
Rf470 (Rotor NO.4) TFA is a FMR-probe-D-lysine conjugate (Max Ex: 470 nM; Max Em: 640 nM) that can be covalently incorporated into peptidoglycan by bacteria. Rf470 TFA has extremely weak fluorescence in the free state, but its fluorescence is significantly enhanced when it is catalytically incorporated into peptidoglycan by transpeptidases. Through fluorescence changes, Rf470 TFA can be used for real-time monitoring of peptidoglycan biosynthesis, detection of transpeptidase activity, and screening of antibiotics, etc .

HY-131086

Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2	ADC Linker	Inflammation/Immunology Cancer
Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W328317

Fast garnet GBC sulfate salt, 90% Azoic diazo NO. 4, 90%	Biochemical Assay Reagents	Others
Fast garnet GBC sulfate salt, 90% is a chromogenic substrate for alkaline phosphatase.

HY-120979

NO-Losartan A	Angiotensin Receptor	Cardiovascular Disease
NO-Losartan A (compound 2a) displays vasorelaxing effects, due to the release of NO, and antagonized the vasocontractile effects of Angiotensin II (HY-13948), with potency values similar to that of Losartan (HY-17512) .

HY-130783

LysoFP-NO2	Fluorescent Dye	Others
LysoFP-NO2 is a turn-on fluorescent probe for carbon monoxide (CO) that localizes to the lysosome. In the presence of lysosomal CO, lysoFP-NO2 is transformed into lysoFP-NH2, which is highly fluorescent. LysoFP-NO2 is selective for CO over various reactive nitrogen, oxygen, and sulfur species. It displays excitation/emission maxima of 440/528 nm, respectively, and is not cytotoxic to HepG2 cells for up to five hours when used at a concentration of 30 μM.

HY-103385

NCX4040 NO-Aspirin	Apoptosis	Inflammation/Immunology Cancer
NCX4040 (NO-Aspirin), a non-steroidal anti-inflammatory drug (NSAID), is a nitric oxide (NO) releasing form of Aspirin. NCX4040 induces apoptosis in PC3 metastatic prostate cancer cells. NCX4040 has anti-inflammatory and anti-cancer effects .

HY-D0307AR

Amaranth (Standard) Acid Red 27 (Standard); Azorubin S (Standard); FD & C Red Dye NO. 2 (Standard)	Fluorescent Dye Reference Standards	Others
Amaranth (Standard) is the analytical standard of Amaranth. This product is intended for research and analytical applications. Amaranth is a dark red to purple azo dye used as a food dye and cosmetics. Amaranth is an anionic dye that can be applied to natural and synthetic fibers, leather, paper, and phenol-formaldehyde resins.

HY-P3725

H-Leu-Ser-Phe(NO2)-Nle-Ala-OMe TFA	Ser/Thr Protease	Others
H-Leu-Ser-Phe(NO2)-Nle-Ala-OMe TFA is a substrate for chymosin .

HY-129876

D-NAME hydrochloride D-NG-nitroarginine methyl ester hydrochloride; H-D-Arg(NO2)-OMe hydrochloride	NO Synthase	Neurological Disease
D-NAME (D-NG-nitroarginine methyl ester) hydrochloride is a potent nitric oxide synthase (NOS) inhibitor. D-NAME hydrochloride inhibits the activity of NOS, reducing the production of nitric oxide .

HY-P4021

Mca-KKEDVV-Abu-CS-Abu-S-(NO2)F-KK-NH2	Amino Acid Derivatives	Others
Mca-KKEDVV-Abu-CS-Abu-S-(NO2)F-KK-NH2 is a L-Lysine (HY-N0469) derivative .

HY-B0696B

Tiagabine hydrochloride hydrate NO050328 hydrochloride hydrate; NO328 hydrochloride hydrate; TGB hydrochloride hydrate	GABA Receptor	Neurological Disease
Tiagabine (NO050328; NO328; TGB) hydrochloride hydrate is an orally active, highly selective, and reversible GAT-1 inhibitor and anticonvulsant that crosses the blood-brain barrier. By blocking the reuptake of GABA in neurons and glial cells, tiagabine increases extracellular GABA levels to enhance inhibitory signal transduction, thereby exerting multiple activities such as anticonvulsant, neuroprotective, and antioxidant effects. Tiagabine hydrochloride hydrate exhibits linear pharmacokinetic properties. Although it is metabolized by CYP3A and has a high protein binding rate, it carries a low risk of cognitive impairment. Tiagabine hydrochloride hydrate is widely used in research on related diseases including epilepsy (including refractory partial seizures), alcohol withdrawal symptoms, and Huntington's disease .

HY-120374

V-PYRRO/NO	Biochemical Assay Reagents	Metabolic Disease
V-PYRRO/NO is a NO donor in vivo. Following hepatic metabolism, it spontaneously decomposes with a half-life of 3 seconds to liberate NO.

HY-W071007

NO2-SPDMV	ADC Linker	Cancer
NO2-SPDMV is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-D2966

TMR-NO-BG	Fluorescent Dye	Others
TMR-NO-BG is a hybrid probe (Ex/Em: 557 nm/571 nm). TMR-NO-BG covalently connects the tetramethylrhodamine (TMR) lactone NO sensing unit with the SNAP-tag reactive benzyl guanine (BG) for achieving subcellular-specific nitric oxide (NO) detection .

HY-D1164

Pigment red 63:1 D&C Red NO. 34	Fluorescent Dye
Pigment red 63:1 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0257R

Tartrazine (Standard) Acid Yellow 23 (Standard); FD&C Yellow NO. 5 (Standard)	Fluorescent Dye Reference Standards	Others
Tartrazine (Standard) is the analytical standard of Tartrazine. This product is intended for research and analytical applications. Tartrazine is an azo acid dye, orange-yellow powder, soluble in water and turns yellow. It is mainly used as a synthetic lemon yellow azo dye for food coloring. It is the most stable colorant.

HY-123630R

Allura Red AC (Standard) FD&C RED NO. 40 (Standard); CI 16035 (Standard)	Fluorescent Dye Interleukin Related 5-HT Receptor IFNAR Reactive Oxygen Species (ROS) Reference Standards	Inflammation/Immunology
Allura Red AC (Standard) is an analytical standard of Allura Red AC. This product is intended for research and analytical applications. Allura Red AC is a food colorant, appearing as a deep red water-soluble powder or granules, used in various applications such as beverages, syrups, candies, and cereals. Allura Red AC can statically quench the intrinsic fluorescence of HSA. Additionally, Allura Red AC is a 5-hydroxytryptamine (5-HT) pathway-associated pro-inflammatory agent, capable of exacerbating experimental colitis. Allura Red AC holds potential for research in inflammatory bowel disease (IBD), intestinal barrier function, and food additive safety .

HY-U00013R

Nitroflurbiprofen (Standard) HCT 1206 (Standard); NO-flurbiprofen (Standard); Nitroxybutyl flurbiprofen (Standard)	Reference Standards COX	Cardiovascular Disease
Nitroflurbiprofen is a cyclooxygenase (COX) inhibitor with nitric oxide (NO)-donating properties, modulates the increased intrahepatic vascular tone in portal hypertensive cirrhotic rats.

HY-P10092

SP6	Akt NO Synthase PI3K	Cardiovascular Disease
SP6 exertes an antihypertensive effect through vascular NO regulation .

HY-131896

FR144420 NOR4	NO Synthase	Cardiovascular Disease
FR144420 (NOR4) is an orally active nitric oxide (NO)-releasing agent with vasodilatory and antiplatelet effects. FR144420 induces cGMP-mediated vasodilation and inhibits platelet aggregation. FR144420 is promising for research of cardiovascular diseases, particularly angina pectoris and coronary artery spasm .

HY-155224

Sulpho NONOate Sulfi/NO	NO Synthase	Others
Sulpho NONOate (Sulfi/NO) does not produce NO at physiological pH. Sulpho NONOate can be used in the experiments about other NO-donor regents as a negative control .

HY-146161

COX-2/NO-IN-1	COX NO Synthase	Inflammation/Immunology
COX-2/NO-IN-1 is an orally active nitric oxide synthase (iNOS), COX-2 expression and NO (IC₅₀ of 3.52 μM) inhibitor. COX-2/NO-IN-1 has anti-inflammatory effects .

HY-163038

Sulfamethoxazole-NO hydrate SMX-NO hydrate	Drug Metabolite	Inflammation/Immunology
Sulfamethoxazole-NO (SMX-NO) hydrate is the reactive metabolite of SMX (HY-B0322). Sulfamethoxazole-NO (SMX-NO) hydrate actis as a typical hapten and is capable of covalently modifying the MHC-peptide complex, can stimulate hapten-reactive T cells .

HY-W415104

D&C Red No. 31	Biochemical Assay Reagents	Others
D&C Red No. 31 is a biochemical assay reagent that can be used for cosmetics research .

HY-B0696AR

Tiagabine hydrochloride (Standard) NO050328 hydrochloride (Standard); NO328 hydrochloride (Standard); TGB hydrochloride (Standard)	Reference Standards GABA Receptor	Neurological Disease
Tiagabine (hydrochloride) (Standard) is the analytical standard of Tiagabine (hydrochloride). This product is intended for research and analytical applications. Tiagabine hydrochloride (NO050328; NO328; TGB) is an orally active, highly selective, and reversible GAT-1 inhibitor and anticonvulsant that crosses the blood-brain barrier. By blocking the reuptake of GABA in neurons and glial cells, tiagabine increases extracellular GABA levels to enhance inhibitory signal transduction, thereby exerting multiple activities such as anticonvulsant, neuroprotective, and antioxidant effects. Tiagabine hydrochloride exhibits linear pharmacokinetic properties. Although it is metabolized by CYP3A and has a high protein binding rate, it carries a low risk of cognitive impairment. Tiagabine hydrochloride is widely used in research on related diseases including epilepsy (including refractory partial seizures), alcohol withdrawal symptoms, and Huntington's disease .

HY-129464

NO-711ME	GABA Receptor	Neurological Disease
NO-711ME is a prodrug of NO-711. NO-711 is a potent and selective GABA uptake inhibitor .

Cat. No.	Product Name	Type

HY-D0915

Brilliant Blue FCF 5 Publications Verification Acid Blue 9; FD&C Blue NO. 1; E133	Fluorescent Dye
Brilliant Blue FCF is an aromatic hydrocarbon, a synthetic dye produced from petroleum and used as a colorant for food and other substances. The solution has a maximum absorption at 628 nm.

HY-D0257

Tartrazine 1 Publications Verification Acid Yellow 23; FD&C Yellow NO. 5	Fluorescent Dye
Tartrazine (Acid Yellow 23; FD&C Yellow No. 5) is an orally active azo acid dye, orange-yellow powder, soluble in water and turns yellow. Tartrazine is mainly used as a synthetic lemon yellow azo dye for food coloring. Tartrazine is the most stable colorant.Tartrazine induces mitochondria-mediated Apoptosis. Tartrazine can cause neurodevelopmental toxicity, cytotoxicity, and genotoxicity .

HY-D0914

Fast Green FCF

FD&C Green NO. 3; Food green 3; C.I. 42053

Fluorescent Dye

Fast Green FCF is a sea green triarylmethane food dye, with absorption maximum ranging from 622 to 626 nm. Fast Green FCF inhibits α-synuclein aggregation, as well as Aβ and P2X4 receptor, and TLR4/Myd88/NF-κB. Fast Green FCF is widely used as a staining agent like quantitative stain for histones at alkaline pH after acid extraction of DNA, and as a protein stain in electrophoresis. Fast Green FCF improves cognitive impairment, depression, relieves pain allergies, and promotes reproductive function .

HY-D0717

DAF-FM DA Maximum Cited Publications 14 Publications Verification DiamiNOfluorescein-FM diacetate	Fluorescent Dye
DAF-FM DA (Diaminofluorescein-FM diacetate) is a fluorescent probe for the detection and bioimaging of nitric oxide (NO). DAF-FM DA spontaneously crosses the plasma membrane and is subsequently cleaved by esterases to generate intracellular DAF-FM (Ex/Em=495/515 nm) .

HY-123630

Allura Red AC

FD&C RED NO. 40; CI 16035

Fluorescent Dye

Allura Red AC is a food colorant, appearing as a deep red water-soluble powder or granules, used in various applications such as beverages, syrups, candies, and cereals. Allura Red AC can statically quench the intrinsic fluorescence of HSA. Additionally, Allura Red AC is a 5-hydroxytryptamine (5-HT) pathway-associated pro-inflammatory agent, capable of exacerbating experimental colitis. Allura Red AC holds potential for research in inflammatory bowel disease (IBD), intestinal barrier function, and food additive safety .

HY-N1442

Acid orange 7

Orange II; D&C Orange NO. 4

Fluorescent Dye

Acid Orange 7 (Orange II; D&C Orange NO. 4) is an azo dye widely used in the textile, food and cosmetic industries. Acid Orange 7 is mainly used as a colorant by combining with fibers and other substances through azo bonds. Acid Orange 7 has a maximum absorption wavelength at 484-485 nm, and the concentration is measured using a UV-visible spectrophotometer. Acid Orange 7 is difficult to degrade and has a certain degree of toxicity. It is often used to study various sewage treatment technologies and photocatalytic degradation reactions, and to evaluate the removal effects of different treatment methods on organic pollutants .

HY-D0307A

Amaranth Acid Red 27; Azorubin S; FD & C Red Dye NO. 2	Fluorescent Dye
Amaranth is an organic azo dye. Amaranth inhibits cellular immune response. Amaranth can be used as a food additive .

HY-D0076

4,5-Diaminofluorescein DAF-2	Fluorescent Dye
4,5-Diaminofluorescein is a fluorescent detector for nitric oxide (NO) in cells and tissues .

HY-126774

DAF-FM 1 Publications Verification	Fluorescent Dye
DAF-FM is a cell-impermeant diaminofluorescein, which can be used as fluorescent indicator for nitric oxide (NO) with good pH tolerance .

HY-D1266

RB-OPD NO-red	Fluorescent Dye
RB-OPD (NO-red) is a o-phenylenediamine (OPD)-locked rhodamine nitric oxide (NO) fluorescent probe with great sensitivity and selectivity (λex=550 nm, λem=590 nm) .

HY-D1509

Phenazine ethosulfate	Fluorescent Dye
Phenazine ethosulfate is a cationic dye (Ex=390 nm, Em=530 nm) and an electron acceptor that can be used in dye-linked enzyme assays. Phenazine ethosulfate is an intermediate for detecting nitric oxide reducatase (Nors) activity with the presence of ascorbic acid .

HY-DY1048

DAF-FM DA (solution)	Fluorescent Dye
DAF-FM DA (Diaminofluorescein-FM diacetate) (solution) is a fluorescent probe for the detection and bioimaging of nitric oxide (NO). DAF-FM DA spontaneously crosses the plasma membrane and is subsequently cleaved by esterases to generate intracellular DAF-FM (Ex/Em=495/515 nm) . Solvent and concentration: DMSO: 2 mM

HY-136884

DAR-4M	Fluorescent Dye
DAR-4M is a fluorescent indicator for nitric oxide (NO) based on the rhodamine chromophore (Ex/Em= 550/572 nm) .

HY-130027

HKOCl-4 1 Publications Verification BXY2142	Fluorescent Dye
HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid with excellent sensitivity and selectivity . HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. E_x: 530 nm; E_m 557 nm.

HY-D0307AR

Amaranth (Standard) Acid Red 27 (Standard); Azorubin S (Standard); FD & C Red Dye NO. 2 (Standard)	Fluorescent Dye
Amaranth (Standard) is the analytical standard of Amaranth. This product is intended for research and analytical applications. Amaranth is a dark red to purple azo dye used as a food dye and cosmetics. Amaranth is an anionic dye that can be applied to natural and synthetic fibers, leather, paper, and phenol-formaldehyde resins.

HY-D2966

TMR-NO-BG	Fluorescent Dye
TMR-NO-BG is a hybrid probe (Ex/Em: 557 nm/571 nm). TMR-NO-BG covalently connects the tetramethylrhodamine (TMR) lactone NO sensing unit with the SNAP-tag reactive benzyl guanine (BG) for achieving subcellular-specific nitric oxide (NO) detection .

HY-D1164

Pigment red 63:1 D&C Red NO. 34	Fluorescent Dye
Pigment red 63:1 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0257R

Tartrazine (Standard) Acid Yellow 23 (Standard); FD&C Yellow NO. 5 (Standard)	Fluorescent Dye
Tartrazine (Standard) is the analytical standard of Tartrazine. This product is intended for research and analytical applications. Tartrazine is an azo acid dye, orange-yellow powder, soluble in water and turns yellow. It is mainly used as a synthetic lemon yellow azo dye for food coloring. It is the most stable colorant.

HY-123630R

Allura Red AC (Standard)

FD&C RED NO. 40 (Standard); CI 16035 (Standard)

Fluorescent Dye

Allura Red AC (Standard) is an analytical standard of Allura Red AC. This product is intended for research and analytical applications. Allura Red AC is a food colorant, appearing as a deep red water-soluble powder or granules, used in various applications such as beverages, syrups, candies, and cereals. Allura Red AC can statically quench the intrinsic fluorescence of HSA. Additionally, Allura Red AC is a 5-hydroxytryptamine (5-HT) pathway-associated pro-inflammatory agent, capable of exacerbating experimental colitis. Allura Red AC holds potential for research in inflammatory bowel disease (IBD), intestinal barrier function, and food additive safety .

HY-D2729

Cy3-NO2-Tre

Fluorescent Dye

Cy3-NO2-Tre is a nitroreductase-responsive cyanine-based fluorescent probe that specifically labels Mycobacterium tuberculosis (Mtb). Cy3-NO2-tre generated fluorescence after activation by a specific nitroreductase, Rv3368c, which is conserved in the Mycobacteriaceae. Cy3-NO2-tre effectively imaged mycobacteria within infected host cells, tracked the infection process, and visualized Mycobacterium smegmatis being endocytosed by macrophages (Ex/Em= 540-550/575-625 nm) .

HY-N1442R

Acid orange 7 (Standard)

Orange II (Standard); D&C Orange NO. 4 (Standard)

Fluorescent Dye

Acid orange 7 (Standard) is the analytical standard of Acid orange 7 (HY-1442). This product is intended for research and analytical applications. Acid Orange 7 (Orange II; D&C Orange NO. 4) is an azo dye widely used in the textile, food and cosmetic industries. Acid Orange 7 is mainly used as a colorant by combining with fibers and other substances through azo bonds. Acid Orange 7 has a maximum absorption wavelength at 484-485 nm, and the concentration is measured using a UV-visible spectrophotometer. Acid Orange 7 is difficult to degrade and has a certain degree of toxicity. Acid Orange 7 is often used to study various sewage treatment technologies and photocatalytic degradation reactions, and to evaluate the removal effects of different treatment methods on organic pollutants .

HY-D0307

Amaranth free acid

Acid Red 27 free acid; Azorubin S free acid; FD & C Red Dye NO. 2 free acid

Fluorescent Dye

Amaranth free acid (Acid Red 27 free acid; Azorubin S free acid; FD & C Red Dye No. 2 free acid) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-D2279

NFL-NH2	Fluorescent Dye
NFL-NH2 is a mitochondrial-targeted near-infrared ratiometric fluorescent probe. NFL-NH2 can rapidly detect NO levels associated with the inflammatory damage degree in rheumatoid arthritis (RA) mice models by ratiometric fluorescence imaging. The excitation wavelength and emission wavelength are 650 nm and 780 nm, respectively .

HY-D2967

Golgi-NO	Fluorescent Dye
Golgi-NO is a Golgi-targeted fluorescent probe for nitric oxide (NO) (Ex/Em: 560 nm/589 nm). Golgi-NO exhibits excellent selectivity for various potential interfering substances. Golgi-NO can be used to study the function of NO within the Golgi apparatus in disease models such as Alzheimer's disease (AD) .

HY-D2731

Cy3-NO2	Fluorescent Dye
Cy3-NO2 is a cyanine-based probe. Cy3-NO2 can be excited by using a 554 nm laser and filtered with a 568 nm laser .

Cat. No.	Product Name	Type

HY-142979

DSPE-PEG 2000 10+ Cited Publications (C2H4O)nC42H82NO10P	Biochemical Assay Reagents
DSPE-PEG 2000 is a PEG polymer containing DSPE and amine end groups. DSPE-PEG 2000 can be used to form micelles as nanoparticles for drug delivery .

HY-W717800A

NO2A-Azide trihydrochloride	Biochemical Assay Reagents
NO2A-Azide (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Azide (trihydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W328317

Fast garnet GBC sulfate salt, 90% Azoic diazo NO. 4, 90%	Biochemical Assay Reagents
Fast garnet GBC sulfate salt, 90% is a chromogenic substrate for alkaline phosphatase.

HY-W749627

NO2A-Butyne	Biochemical Assay Reagents
NO2A-Butyneis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Butyne can be used for conjugation of peptides and radionuclides.

HY-W782075

p-NO2-Bn-DOTA	Biochemical Assay Reagents
p-NO2-Bn-DOTAis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-NO2-Bn-DOTA can be used for conjugation of peptides and radionuclides.

HY-W717742

p-NO2-Bn-Cyclen	Biochemical Assay Reagents
p-NO2-Bn-Cyclenis a bifunctional chelator (Bifunctional Chelator; BFC), which is a derivative of the macrocyclic ligand dodecane backbone Cyclen. p-NO2-Bn-Cyclen can be used for conjugation of peptides and radionuclides.

HY-W717833

NO2A-(t-Bu ester)	Biochemical Assay Reagents
NO2A-(t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-(t-Bu ester) can be used for conjugation of peptides and radionuclides.

HY-W749614

NO2A-Butyne-bis(t-Butyl ester)	Biochemical Assay Reagents
NO2A-Butyne-bis(t-Butyl ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Butyne-bis(t-Butyl ester) can be used for conjugation of peptides and radionuclides.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0455

L-Arginine Maximum Cited Publications 23 Publications Verification	Cardiovascular Disease Structural Classification Classification of Application Fields Amino acids Endogenous metabolite Disease Research Fields Source Classification Cancer	Environmental Pollutants Endogenous Metabolite NO Synthase
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-N0455A

L-Arginine hydrochloride Maximum Cited Publications 23 Publications Verification (S)-(+)-Arginine hydrochloride	Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	NO Synthase Endogenous Metabolite
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-N1430

Oxyresveratrol 3 Publications Verification trans-Oxyresveratrol	other families Stilbenes Classification of Application Fields Anti-aging Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Tyrosinase HSV Autophagy
Oxyresveratrol (trans-Oxyresveratrol) is a potent naturally occurring antioxidant and free radical scavenger (IC₅₀ of 28.9 µM against DPPH free radicals). Oxyresveratrol is potent and noncompetitive tyrosinase inhibitor with an IC₅₀ value of 1.2 µM for mushroom tyrosinase. Oxyresveratrol is effective against HSV-1, HSV-2 and varicella-zoster virus, and has neuroprotective effects .

HY-W074890

Palmitoylglycine 1 Publications Verification N-palmitoyl glycine	Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Calcium Channel NO Synthase
Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA .

HY-N0455R

L-Arginine (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Amino acids Endogenous metabolite Source Classification	Reference Standards NO Synthase Endogenous Metabolite
L-Arginine (Standard) is the analytical standard of L-Arginine. This product is intended for research and analytical applications. L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-N0268

Irisflorentin 4 Publications Verification	Flavonoids Iridaceae Classification of Application Fields Plants Belamcanda chinensis (Linn.) Redouté Inflammation/Immunology Disease Research Fields Isoflavones Source Classification	NO Synthase
Irisflorentin, a naturally occurring isoflavone, is an abundant active constituent in Belamcanda chinensis. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Anti-inflammatory activity .

HY-N8307

Syringaresinol	Structural Classification Dracaena cambodiana Pierre ex Gagnep. Lignans Phenols Polyphenols Phenylpropanoids Agavaceae Plants	NO Synthase NF-κB Akt AMPK Calcium Channel
Syringaresinol is a lignan-type phytochemical with anti-inflammatory activities. Syringaresinol inhibits the NF-κB and AKT signaling pathway in IL-1β-activated mouse chondrocytes. Syringaresinol increases phosphorylation of AMPK, eNOS, and intracellular Ca ²⁺ levels in HUVECs. Syringaresinol attenuates osteoarthritis progression in mice with Destabilization of the Medial Meniscus (DMM)-induced osteoarthritis. Syringaresinol can be used for the study of osteoarthritis (OA) .

HY-W011849

Phenyl β-D-glucopyranoside	Crassulaceae Rhodiola imbricata Edgew. Plants Source Classification	NF-κB COX NO Synthase MMP
Phenyl β-D-glucopyranoside is a component isolated from Phellodendron amurense, which has anti-inflammatory and anti-tumor activities. Phenyl β-D-glucopyranoside inhibits nitric oxide (NO) production, and the expression of iNOS and COX-2. Phenyl β-D-glucopyranoside also inhibits the nuclear translocation of NF-κB. Phenyl β-D-glucopyranoside inhibits the expression of pro-inflammatory cytokines and related genes .

HY-N3245

Moracin C 1 Publications Verification	Phenols Polyphenols Plants Moraceae Source Classification	Reactive Oxygen Species (ROS) COX
Moracin C, a natural product, is an anti-inflammatory agent. Moracin C inhibits LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) release from cells .

HY-W109812

Sinapyl alcohol	Monophenols Microorganisms Phenols Source Classification	COX
Sinapyl alcohol is an orally active anti-inflammatory and antinociceptive agent. Sinapyl alcohol reduces the expression level of inducible NO synthase and COX-2 .

HY-N0918

Desmethoxyyangonin Demethoxyyangonin; 5,6-Dehydrokavain	other families Classification of Application Fields Other Diseases Other Phenylpropanoids Phenylpropanoids Plants Disease Research Fields Source Classification	Monoamine Oxidase JAK IKK STAT NO Synthase Cytochrome P450
Desmethoxyyangonin is one of the six major kavalactones found in the Piper methysticum (kava) plant. Desmethoxyyangonin is a selective inhibitor of monoamine oxidase-B (MAO-B) (IC₅₀: 0.123 µM). Desmethoxyyangonin exerts anti-inflammatory effects by inhibiting Jak2/STAT3 and IKK signaling pathways. Desmethoxyyangonin induces CYP3A23 expression and leads to skeletal muscle relaxation .

HY-113469A

Cyclic GMP sodium 1 Publications Verification	Natural Products Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
Cyclic GMP (cGMP) sodium, an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP sodium occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses .

HY-W007539

2,4-Dihydroxybenzaldehyde	Monophenols Ketones, Aldehydes, Acids Phenols Polyphenols Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Drug Intermediate NO Synthase Reactive Oxygen Species (ROS) COX
2,4-Dihydroxybenzaldehyde is an endogenous metabolite. 2,4-Dihydroxybenzaldehyde is a pharmaceutical intermediate that can be used to synthesize various Schiff base compounds. 2,4-Dihydroxybenzaldehyde exhibits significant anti angiogenic, anti-inflammatory, and analgesic activities. 2,4-Dihydroxybenzaldehyde reduces the production of NO and ROS by inhibiting the expression of iNOS and COX-2. 2,4-Dihydroxybenzaldehyde is commonly used in the study of inflammatory conditions .

HY-N2620

Rutaevin	Other Terpenoids Classification of Application Fields Terpenoids Evodia rutaecarpa (Juss.) Benth. Rutaceae Plants Disease Research Fields Inflammation/Immunology Source Classification	Reactive Oxygen Species (ROS)
Rutaevin is isolated from the fruits of Euodia rutaecarpa. Rutaevin inhibits NO production in LPS-induced RAW 264.7 macrophages .

HY-125531

Dactylorhin A	Bletilla striata (Thunb. ex Murray) Rchb. f. Classification of Application Fields Ketones, Aldehydes, Acids Orchidaceae Other Diseases Plants Disease Research Fields Source Classification	Others
Dactylorhin A, a succinate derivative ester, is isolated from rhizomes of Gymnadenia conopsea. Dactylorhin A exhibits moderate inhibitory effects on NO production effects in RAW 264.7 macrophage cells .

HY-N2008

Luteolin 5-O-glucoside	Flavonoids Classification of Application Fields Flavones Vigna angularis (Willd.) Ohwi et Ohashi Plants Compositae Inflammation/Immunology Disease Research Fields	NO Synthase Reactive Oxygen Species (ROS)
Luteolin 5-O-glucoside, a major flavonoidfrom Cirsium maackii, possesses anti-inflammatory activity. Luteolin 5-O-glucoside inhibits LPS-induced NO production and t-BHP-induced ROS generation. Luteolin 5-O-glucoside suppresses the expression of iNOS and COX-2 in macrophages .

HY-W005963

Methyl 5-hydroxypyridine-2-carboxylate	Alkaloids Classification of Application Fields Pyridine Alkaloids Plants Compositae Desmodium uncinatum DC. Inflammation/Immunology Disease Research Fields Source Classification	NO Synthase
Methyl 5-hydroxypyridine-2-carboxylate is a phenolic acid that can found in the stems of Mahonia fortune. Methyl 5-hydroxypyridine-2-carboxylate exhibits NO inhibitory effects in vitro .

HY-N9337

Amaroswerin	Iridoids Classification of Application Fields Terpenoids Gentianaceae Phenols Polyphenols Metabolic Disease Swertia mussotii Franch. Plants Disease Research Fields Inflammation/Immunology Source Classification	NO Synthase
Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC₅₀ value of 5.42 μg/mL in RAW264.7 cells .

HY-N3188

Niloticin	Infection Triterpenes Phellodendron chinense Schneid. Classification of Application Fields Terpenoids Rutaceae Plants Disease Research Fields Source Classification	Akt NF-κB
Niloticin, tetracyclic triterpenoid compound, is a osteoclastogenesis inhibitor. Niloticin shows anti-viral, antioxidative, and mosquitocidal activities. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways .

HY-N3915

Futoquinol	Other Phenylpropanoids Piperaceae Phenylpropanoids Plants Piper kadsura (Choisy) Ohwi Source Classification	NO Synthase
Futoquinol is a neolignan isolated from the dried aerial parts of Piper kadsura (Piperaceae). Futoquinol potently inhibits NO production in microglia cells. Futoquinol has anti-neuroinflammatory activities .

HY-N9369

Verbascose	Classification of Application Fields Polygalaceae Plants Disease Research Fields Inflammation/Immunology Polygala tatarinowii Regel Saccharides Source Classification	Others
Verbascose, an alacto-oligosac-charides (GOS), has potent immunostimulatory activity. Verbascose acts as a potential natural immunomodulatory agent .

HY-N9347

Stepharine 3 Publications Verification	Cardiovascular Disease Alkaloids other families Classification of Application Fields Plants Isoquinoline Alkaloids Disease Research Fields Source Classification	Toll-like Receptor (TLR)
Stepharine, an natural alkaloid, directly interactes with TLR4 and binds to the TLR4/MD2 complex (TLR4 inhibitor). Stepharine possesses anti-aging, anti-viral and anti-hypertensive effects .

HY-N8631

O-Acetylschisantherin L Acetylschisantherin L	Lignans Phenylpropanoids Plants Kadsura coccinea (Lem.) A. C. Smith Schisandraceae Source Classification	NO Synthase
O-Acetylschisantherin L (Acetylschisantherin L) is a natural lignan, which exhibits inhibitory effects on LPS-induced NO production in BV-2 cells with an IC₅₀ of 23.1 μM .

HY-N13184

Giraldoid B	Thymelaeaceae Daphne giraldii Nitsche Coumarins Phenylpropanoids Plants Source Classification	TNF Receptor
Giraldoid B is an active ingredient that can be isolated from Girald Daphne Bark. Giraldoid B can inhibit LPS induced NO and b>TNF-α production in RAW264.7 and has anti-inflammatory activity .

HY-N3480

Isogosferol (+)-Isogospherol; Isogospherol	Coumarins Ageratina altissima (L.) R.M.King & H.Rob. Phenylpropanoids Umbelliferae Plants Source Classification	Others
Isogosferol ((+)-Isogospherol; Isogospherol) is a potent anti-inflammatory agent. Isogosferol decreases LPS (HY-D1056)-stimulated NO and IL-1β expression. Isogosferol decreases the LPS (HY-D1056)-stimulated expression of iNOS, COX-2, NF-κB, and pERK1/2 .

HY-N10603

Praeroside Baihuaqianhuoside	Natural Products Carpesium divaricatum Siebold & Zucc. Plants Umbelliferae	Others
Praeroside (Baihuaqianhuoside), a coumarin glycoside. Praeroside can be extracted from the root of Peucedanum praeruptorum and Heracleum dissectum. Praeroside shows anti-inflammatory activity in vitro. Praeroside can be used for the research of inflammation .

HY-W074890R

Palmitoylglycine (Standard) N-palmitoyl glycine (Standard)	Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Calcium Channel NO Synthase
Palmitoylglycine (Standard) is the analytical standard of Palmitoylglycine. This product is intended for research and analytical applications. Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA[1][2][3].

HY-N3211

N-cis-Feruloyl tyramine cis-N-(4-Hydroxyphenethyl) ferulamide; cis-N-Feruloyltyramine	Annona cherimola Mill. Phenols Polyphenols Plants Annonaceae Source Classification	NO Synthase
N-cis-Feruloyl tyramine (cis-N-(4-Hydroxyphenethyl) ferulamide) is a natural phenolic compound, exhibits modest inhibitory activity on LPS-activated NO production in RAW 264.7 cells .

HY-N3550

Catalponol	Other Terpenoids Catalpa ovata G. Don Classification of Application Fields Terpenoids Bignoniaceae Plants Disease Research Fields Source Classification Cancer	Others
Catalponol is a naphthoquinone derivative. Catalponol enhances dopamine biosynthesis by inducing tyrosine hydroxylase activity. Catalponol also increases the levels of cAMP and tyrosine hydroxylase phosphorylation in PC12 cells .

HY-N7006

Timosaponin C Anemarsaponin C	Liliaceae Classification of Application Fields Anemarrhena asphodeloides Bunge Plants Disease Research Fields Inflammation/Immunology Steroids Source Classification	Others
Timosaponin C is isolated from Rhizoma Anemarrhenae . Timosaponin C shows weaker NO inhibition in N9 microglial cells .

HY-N2989

3-O-Acetyl-16α-hydroxydehydrotrametenolic acid	Other Terpenoids Classification of Application Fields Terpenoids Polyporaceae Poria cocos Plants Disease Research Fields Inflammation/Immunology Source Classification	NO Synthase
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid, an anti-inflammatory triterpenoid, inhibits NO production and iNOS expression in LPS-stimulated Raw264.7 cells .

HY-N10023

Physalin O	Physalis minima Linn. Cardiacglycosides Plants Solanaceae Steroids Source Classification	NO Synthase
Physalin O is a physalin that can be isolated from Physalis angulata. Physalin O shows cytotoxicity to Hep G2 and MCF-7 cancer cells with IC₅₀ values of 31.1 and 11.4 µM, respectively. Physalin O inhibits the production of nitric oxide (NO) and shows anti-inflammatory activities .

HY-N4190

Britannilactone diacetate 1,6-O,O-Diacetylbritannilactone; Di-O-acetylbritannilactone	Structural Classification Terpenoids Sesquiterpenes Plants Compositae Piptanthus nepalensis (Hook.) D. Don Source Classification	NO Synthase
Britannilactone diacetate (1,6-O,O-Diacetylbritannilactone; Compound 2) exhibits potential NO inhibition effect. Britannilactone diacetate exhibits activity against NO production induced by LPS in BV-2 microglial cells with the EC₅₀ value of 6.3 μM. Britannilactone diacetate exhibits a favorable blood-brain barriers (BBB) penetration and absorption, distribution, metabolism, excretion, and toxicity (ADMET) property .

HY-N12283

NF-κB-IN-13	Natural Products Thymelaeaceae Plants Aquilaria sinensis (Lour.) Spreng. Source Classification	NF-κB
NF-κB-IN-13 (compound 12) can significantly inhibit LPS-induced NF-κB activation and NO production in RAW264.7 macrophages. NF-κB-IN-13 has anti-inflammatory effects .

HY-N17678

(E)-Sinapoyl glucose Raphanusol B	Structural Classification Plants Brassica oleracea var. gongylodes L. Brassicaceae Saccharides Monosaccharides Source Classification	Drug Derivative NO Synthase
(E)-Sinapoyl glucose is an inflammatory pathway inhibitor. (E)-Sinapoyl glucose inhibits NO production in RAW 264.7 cells with an IC₅₀ value of 38.32 µM. (E)-Sinapoyl glucose is promising for research of inflammatory diseases .

HY-N7647

Methyl brevifolincarboxylate Brevifolincarboxylic acid methyl ester	Infection Natural Products Classification of Application Fields Canarium album (Lour.) Rauesch. Plants Burseraceae Disease Research Fields Source Classification	Influenza Virus
Methyl brevifolincarboxylate (Brevifolincarboxylic acid methyl ester) is a potent influenza virus PB2 cap-binding inhibitor. Methyl brevifolincarboxylate has anti-oxidant activity. Methyl brevifolincarboxylate also inhibits platelet aggregation, lipid metabolism and inflammation .

HY-N8413

Chlojaponilactone B	Terpenoids Sesquiterpenes Chloranthaceae Chloranthus japonicus Sieb. Plants Source Classification	Toll-like Receptor (TLR) Reactive Oxygen Species (ROS) NF-κB
Chlojaponilactone B is a lindenane-type sesquiterpenoid with anti-inflammatory properties. Chlojaponilactone B suppresses inflammatory responses by inhibiting TLR4 and subsequently decreasing reactive oxygen species (ROS) generation, downregulating the NF-κB, thus reducing the expression of the pro-inflammatory cytokines iNOS, NO, COX-2, IL-6 and TNF-α .

HY-N1430R

Oxyresveratrol (Standard) trans-Oxyresveratrol (Standard)	Structural Classification other families Stilbenes Phenols Polyphenols Plants Source Classification	Reference Standards Tyrosinase HSV Autophagy
Oxyresveratrol (Standard) is the analytical standard of Oxyresveratrol. This product is intended for research and analytical applications. Oxyresveratrol (trans-Oxyresveratrol) is a potent naturally occurring antioxidant and free radical scavenger (IC50 of 28.9 μM against DPPH free radicals). Oxyresveratrol is potent and noncompetitive tyrosinase inhibitor with an IC50 value of 1.2 μM for mushroom tyrosinase. Oxyresveratrol is effective against HSV-1, HSV-2 and varicella-zoster virus, and has neuroprotective effects .

HY-N8477

Isolupalbigenin	Flavonoids Maclura tricuspidata Carriere Plants Moraceae Isoflavones Source Classification	NO Synthase
Isolupalbigenin is an inhibitor of NO. Isolupalbigenin has anti-proliferative activity on HL-60 cells with an IC₅₀ of 5.1 μM .

HY-N12042

Taxamairin B	Terpenoids Taxaceae Diterpenoids Plants Source Classification Taxus wallichiana var. mairei (Lemee & H. Léveillé) L. K. Fu & Nan Li	TNF Receptor PI3K Reactive Oxygen Species (ROS) Interleukin Related
Taxamairin B is a potent anti-inflammatory agent. Taxamairin B decreases proinflammatory cytokines (TNF-α, IL-1β and IL-6) expression and the production of NO and ROS in LPS-induced RAW264.7 cells. Taxamairin B exhibits significant protective effects in LPS-induced acute lung injury in mice .

HY-N1158

Thevebioside	Apocynaceae Structural Classification Thevetia peruviana (Pers.) K. Schum. Plants Steroids Source Classification	Others
Tinospinoside C is a bioactive clerodane diterpene glycoside compound. Tinospinoside C shows inhibitory activities of NO production with an IC₅₀ value of 218 μM .

HY-N1152

threo-Guaiacylglycerol beta-coniferyl ether	Dalbergia tonkinensis Prain Lignans Phenylpropanoids Plants Compositae Source Classification	Others
threo-Guaiacylglycerol beta-coniferyl ether is a lignan that can inhibit NO production. threo-Guaiacylglycerol beta-coniferyl ether exhibits anti-neuroinflammatory activities .

HY-N7483

1-Dehydroxybaccatin IV	Structural Classification Classification of Application Fields Terpenoids Taxaceae Metabolic Disease Diterpenoids Taxus yunnanensis W.C.Cheng & L.K.Fu Plants Disease Research Fields Source Classification	Others
1-Dehydroxybaccatin IV is a taxane diterpene. 1-Dehydroxybaccatin IV shows concentration-dependent NO inhibition, with an IC₅₀ of 32.2 μM .

HY-N2794

9-Hydroxy-α-lapachone α-Dihydrocaryopterone	Quinones Catalpa ovata G. Don Monophenols Phenols Plants Bignoniaceae Naphthalene Quinones Source Classification	NO Synthase
9-Hydroxy-α-lapachone (α-Dihydrocaryopterone) is a natural phenol, exhibits potent inhibitory effects with an IC₅₀ of 4.64 µM on LPS-induced NO production in RAW 264.7 cells .

HY-113469AR

Cyclic GMP sodium (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Cyclic GMP sodium (Standard) is the analytical standard of Cyclic GMP sodium (HY-113469A). This product is intended for research and analytical applications. Cyclic GMP (cGMP) sodium, an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP sodium occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses .

HY-142100

Licoagrochalcone C	Glycyrrhiza glabra Linn. Flavonoids Leguminosae Plants Other Flavonoids Source Classification	NF-κB
Licoagrochalcone C, a flavonoid, reveals efficacious inhibitory activity on NF-κB transcription. Licoagrochalcone C shows significant inhibitory activity on LPS (HY-D1056)-induced NO production .

HY-N8174

Valeriandoid F	Valeriana jatamansi Jones Iridoids Classification of Application Fields Terpenoids Plants Valerianaceae Inflammation/Immunology Disease Research Fields Source Classification	NO Synthase
Valeriandoid F is an iridoid, which potently inhibits NO production with an IC₅₀ value of 0.88 μM. Valeriandoid F has anti-inflammatory and antiproliferative activities .

HY-124508

Lambertellin	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial Fungal p38 MAPK NF-κB
Lambertellin is an effective antibiotic that can be used as a bactericide and as a fungicide. Lambertellin exerts its anti-inflammatory effect in LPS (HY-D1056)-stimulated RAW 264.7 macrophage cells by modulating the activation of the MAPK and NF-κB signaling pathways .

HY-130787

Apterin	Carpesium divaricatum Siebold & Zucc. Plants Umbelliferae Saccharides Monosaccharides Source Classification	NO Synthase
Apterin is a natural compound with anti-inflammatory activity. Apterin shows significantly inhibitory activity on NO production in RAW264.7 cells with an IC₅₀ value of 41.8 μM .

HY-N9969

Lupulone C	Natural Products Classification of Application Fields Humulus lupulus L. Plants Moraceae Disease Research Fields Inflammation/Immunology Source Classification	Others
Lupulone C (Compound 9) is an inhibitor of NO production .

Species:	Human (3) Mouse (1) E.coli (1)
Tag:	SUMO (1) His (3) GST (4)
Source:	Sf9 insect cells (3) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P700386

	YTFE Protein, E.coli (GST) Iron-sulfur cluster repair protein YtfE; Regulator of cell morphogenesis and NO signaling; RCMNS	E.coli	E. coli
	YTFE protein is a diiron-containing molecule that is crucially involved in the repair of iron-sulfur clusters under oxidative and nitrosative stress conditions. As a homodimer, YTFE plays a key role in mitigating damage to iron-sulfur clusters, a process necessary to maintain the integrity and function of various proteins within cells. YTFE Protein, E.coli (GST) is the recombinant E. coli-derived YTFE protein, expressed by E. coli , with N-GST labeled tag.

HY-P71574

	Nucleophosmin/Npm1 Protein, Mouse (His-SUMO) Npm1; Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin	Mouse	E. coli
	The nucleophosmin/Npm1 protein is a multifunctional nucleolar phosphoprotein involved in multiple cellular processes, including ribosome assembly and transport, DNA repair, and centrosome duplication.It plays a crucial role in maintaining genome stability and regulating cell proliferation.Nucleophosmin/Npm1 Protein, Mouse (His-SUMO) is the recombinant mouse-derived Nucleophosmin/Npm1 protein, expressed by E.coli , with N-His, N-SUMO labeled tag.

HY-P705597

	WNK3 Protein, Human (Active, sf9, GST) WNK3; KIAA1566; PRKWNK3; Protein kinase lysine-deficient 3; Protein kinase with NO lysine 3; EC:2.7.11.1	Human	Sf9 insect cells

HY-P705584

	WNK4 Protein, Human (sf9, His-GST) Serine/threonine-protein kinase WNK4; Protein kinase lysine-deficient 4; Protein kinase with NO lysine 4; PRKWNK4; EC:2.7.11.1	Human	Sf9 insect cells

HY-P703072

	WNK1 Protein, Human (sf9, His, GST) Erythrocyte 65 kDa protein; p65; Kinase deficient protein; Protein kinase lysine-deficient 1; Protein kinase with NO lysine 1; HSN2; KDP, KIAA0344; PRKWNK1	Human	Sf9 insect cells
	WNK1 Protein, Human (sf9, His, GST) is the recombinant human-derived WNK1, expressed by sf9 insect cells , with N-GST, N-His labeled tag. ,

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Cat. No.	Product Name	Chemical Structure

HY-Y0882S1

Hydroxylamine-d3 hydrochloride

Hydroxylamine-d₃ (hydrochloride) is the deuterium labeled Hydroxyamine hydrochloride. Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N₂O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity .

HY-W748332

PCB118-13C12
PCB118- ¹³C₁₂ (CDE-99- ¹³C₁₂; PCB No 118- ¹³C₁₂; 2,3',4,4',5-Pentachlorobiphenyl- ¹³C₁₂) is ¹³C labeled PCB118 .

HY-B0442AS

Vardenafil-d5 hydrochloride

Vardenafil-d₅ hydrochloride is deuterated labeled Vardenafil hydrochloride (HY-B0442A). Vardenafil hydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC₅₀ of 0.7 nM. Vardenafil hydrochloride shows inhibitory towards PDE1, PDE6 with IC₅₀s of 180 nM, and 11 nM, while IC₅₀s are >1000 nM for PDE3 and PDE4 . Vardenafil hydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels . Vardenafil hydrochloride can be used for the research of erectile dysfunction, hepatitis, diabetes ^[1]-[6].

HY-15287S1

Nelfinavir-d4
Nelfinavir-d₄ is deuterated labeled Nelfinavir (HY-15287). Nelfinavir (AG-1341) is a potent and orally bioavailable HIV-1 protease inhibitor (K_i=2 nM) for HIV infection. Nelfinavir is a broad-spectrum, anticancer agent .

HY-B0696AS

Tiagabine-d4 hydrochloride

Tiagabine-d₄ hydrochloride is deuterated labeled Tiagabine hydrochloride (HY-B0696A). Tiagabine hydrochloride (NO050328; NO328; TGB) is an orally active, highly selective, and reversible GAT-1 inhibitor and anticonvulsant that crosses the blood-brain barrier. By blocking the reuptake of GABA in neurons and glial cells, tiagabine increases extracellular GABA levels to enhance inhibitory signal transduction, thereby exerting multiple activities such as anticonvulsant, neuroprotective, and antioxidant effects. Tiagabine hydrochloride exhibits linear pharmacokinetic properties. Although it is metabolized by CYP3A and has a high protein binding rate, it carries a low risk of cognitive impairment. Tiagabine hydrochloride is widely used in research on related diseases including epilepsy (including refractory partial seizures), alcohol withdrawal symptoms, and Huntington's disease .

HY-B0696S

Tiagabine-d6

Tiagabine-d₆ (NO050328-d₆) is deuterium labeled Tiagabine. Tiagabine (NO050328; NO328; TGB) is an orally active, highly selective, and reversible GAT-1 inhibitor and anticonvulsant that crosses the blood-brain barrier. By blocking the reuptake of GABA in neurons and glial cells, tiagabine increases extracellular GABA levels to enhance inhibitory signal transduction, thereby exerting multiple activities such as anticonvulsant, neuroprotective, and antioxidant effects. Tiagabine exhibits linear pharmacokinetic properties. Although it is metabolized by CYP3A and has a high protein binding rate, it carries a low risk of cognitive impairment. Tiagabine is widely used in research on related diseases including epilepsy (including refractory partial seizures), alcohol withdrawal symptoms, and Huntington's disease .

HY-W414846S

2,3,4'-Trichlorobiphenyl-d4
2,3,4'-Trichlorobiphenyl-d₄ is the deuterium labeled 2,3,4'-Trichlorobiphenyl .

HY-W750212

Acid Orange 7-13C6

Acid Orange 7- ¹³C₆ (Orange II- ¹³C₆) is the ¹³C-labeled Acid orange 7 (HY-N1442). Acid Orange 7 (Orange II; D&C Orange NO. 4) is an azo dye widely used in the textile, food and cosmetic industries. Acid Orange 7 is mainly used as a colorant by combining with fibers and other substances through azo bonds. Acid Orange 7 has a maximum absorption wavelength at 484-485 nm, and the concentration is measured using a UV-visible spectrophotometer. Acid Orange 7 is difficult to degrade and has a certain degree of toxicity. It is often used to study various sewage treatment technologies and photocatalytic degradation reactions, and to evaluate the removal effects of different treatment methods on organic pollutants .

HY-W109812S

Sinapyl alcohol-d3
Sinapyl alcohol-d₃ is the deuterated labeled Sinapyl alcohol (HY-W109812). Sinapyl alcohol is an orally active anti-inflammatory and antinociceptive agent. Sinapyl alcohol reduces the expression level of inducible NO synthase and COX-2 .

HY-158252S

Tiagabine-d5 hydrochloride

Tiagabine-d₅ (hydrochloride) is deuterium labeled Tiagabine (hydrochloride). Tiagabine hydrochloride (NO050328; NO328; TGB) is an orally active, highly selective, and reversible GAT-1 inhibitor and anticonvulsant that crosses the blood-brain barrier. By blocking the reuptake of GABA in neurons and glial cells, tiagabine increases extracellular GABA levels to enhance inhibitory signal transduction, thereby exerting multiple activities such as anticonvulsant, neuroprotective, and antioxidant effects. Tiagabine hydrochloride exhibits linear pharmacokinetic properties. Although it is metabolized by CYP3A and has a high protein binding rate, it carries a low risk of cognitive impairment. Tiagabine hydrochloride is widely used in research on related diseases including epilepsy (including refractory partial seizures), alcohol withdrawal symptoms, and Huntington's disease .

HY-B0696S1

Tiagabine-d4

Tiagabine-d₄ (NO050328-d₄) is deuterium labeled Tiagabine. Tiagabine (NO050328; NO328; TGB) is an orally active, highly selective, and reversible GAT-1 inhibitor and anticonvulsant that crosses the blood-brain barrier. By blocking the reuptake of GABA in neurons and glial cells, tiagabine increases extracellular GABA levels to enhance inhibitory signal transduction, thereby exerting multiple activities such as anticonvulsant, neuroprotective, and antioxidant effects. Tiagabine exhibits linear pharmacokinetic properties. Although it is metabolized by CYP3A and has a high protein binding rate, it carries a low risk of cognitive impairment. Tiagabine is widely used in research on related diseases including epilepsy (including refractory partial seizures), alcohol withdrawal symptoms, and Huntington's disease .

Host:	Mouse (2) Rabbit (5)
Reactivity:	Human (5) Rat (4) Mouse (5) Species independent (1) human (1)
Application:	IHC-P (4) ICC/IF (4) IP (2) IHC-F (2) WB (6) FC (1) ELISA (2)
Isotype:	IgG (5) IgG1 (1) IgG2a (1)
Conjugation:	Non-conjugated (7)
Clonality:	Polyclonal (2) Monoclonal (4) Recombinant (2)
Modification:	Unmodified (7)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P810019

	NO66 Antibody (YA9363)	WB, IP	human
	NO66 Antibody (YA9363) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NO66.

HY-P81216

	3-Nitrotyrosine Antibody 1 Publications Verification NO tyrosine; nTyr; Nitrotyrosine; nitro-Tyrosine; nitro Tyrosine.	WB, IHC-P, IHC-F, ICC/IF, FC	Species independent
	3-Nitrotyrosine Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to 3-Nitrotyrosine.

HY-P83497

	Mint3 Antibody (YA3242) Histone lysine demethylase MINA; MDIG; MINA; NO52; ROX	WB, ICC/IF	Human, Mouse
	Mint3 Antibody (YA3242) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mint3.

HY-P86052

	Nucleophosmin Antibody (YA5744) Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin;	IHC-P, ELISA	Human, Mouse, Rat
	Nucleophosmin Antibody (YA5744) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Nucleophosmin.

HY-P80725

	iNOS Antibody 3 Publications Verification NOS2; NOS2A; Nitric oxide synthase; inducible; Hepatocyte NOS; HEP-NOS; Inducible NO synthase; Inducible NOS; iNOS; NOS type II; Peptidyl-cysteine S-nitrosylase NOS2	WB, IHC-P, IHC-F, ICC/IF	Human, Mouse, Rat
	iNOS Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to iNOS.

HY-P86080

	iNOS Antibody (YA5772) NOS2; NOS2A; Nitric oxide synthase; inducible; Hepatocyte NOS; HEP-NOS; Inducible NO synthase; Inducible NOS; iNOS; NOS type II; Peptidyl-cysteine S-nitrosylase NOS2	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	iNOS Antibody (YA5772) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to iNOS.

HY-P82468

	WNK1 Antibody (YA2213) WNK1; HSN2; KDP; KIAA0344; PRKWNK1; Serine/threonine-protein kinase WNK1; Erythrocyte 65 kDa protein; p65; Kinase deficient protein; Protein kinase lysine-deficient 1; Protein kinase with NO lysine 1; hWNK1	WB, IHC-P	Human, Mouse, Rat
	WNK1 Antibody (YA2213) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to WNK1.

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Clonality
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Appearance
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SwissProt ID
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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-W717800A

NO2A-Azide trihydrochloride		Azide
NO2A-Azide (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Azide (trihydrochloride) can be used for conjugation of peptides and radionuclides.

HY-W749627

NO2A-Butyne		Alkynes
NO2A-Butyneis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Butyne can be used for conjugation of peptides and radionuclides.

HY-W749614

NO2A-Butyne-bis(t-Butyl ester)		Alkynes
NO2A-Butyne-bis(t-Butyl ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Butyne-bis(t-Butyl ester) can be used for conjugation of peptides and radionuclides.

Cat. No.	Product Name		Classification

HY-N0455

L-Arginine Maximum Cited Publications 23 Publications Verification		Solubilizing Agents
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-142979

DSPE-PEG 2000 10+ Cited Publications (C2H4O)nC42H82NO10P		Pegylated Lipids
DSPE-PEG 2000 is a PEG polymer containing DSPE and amine end groups. DSPE-PEG 2000 can be used to form micelles as nanoparticles for drug delivery .

HY-150738

ODN 2088 3 Publications Verification		CpG ODNs
ODN 2088 is a potent TLR3, TLR7 and TLR9 inhibitor. ODN 2088 shows no cytotoxic. ODN 2088 inhibits the release of IFN-α and IL-6 .

HY-143220

SS(no Galnac)-Inclisiran sodium		siRNAs siRNA drugs
SS (no Galnac)-Inclisiran sodium is the sense strand of Inclisiran (HY-132591) without GalNAc modification. Inclisiran is a double-stranded small interfering RNA (siRNA) molecule that inhibits the transcription of PCSK-9. SS (no Galnac)-Inclisiran sodium can be used in cardiovascular disease research .

HY-150738C

ODN 2088 sodium 3 Publications Verification		CpG ODNs
ODN 2088 sodium is a potent TLR3, TLR7 and TLR9 inhibitor. ODN 2088 sodium shows no cytotoxic. ODN 2088 inhibits the release of IFN-α and IL-6 .

HY-RS09434

Nos1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Nos1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nos1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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