1 Result for "

PLEOF hydrogels

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "PLEOF hydrogels" in MCE Product Catalog:

IKVAVC
IKVAVC
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Cat. No.: HY-P11753
CAS No.: 1187540-64-2
Target:  

TGF-beta/Smad

Research Areas:  

Neurological Disease Inflammation/Immunology

IKVAVC is a derivative peptide of IKVAV with an artificially added cysteine (Cys) at its C-terminus. IKVAVC retains all the biological activities of the original IKVAV, mainly acting as a neural adhesion/differentiation signaling peptide, and is equipped with an engineered linker arm that enables covalent conjugation to molecular materials. IKVAV inhibits the migration and activation of fibroblasts, downregulates the TGF-β1 signaling pathway and endoplasmic reticulum stress, and promotes nerve repair. IKVAV regulates the phenotype of macrophages, shifting them from the pro-inflammatory M1 type to the pro-reparative M2 type .
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